Clinical trials: Environmental Exposure
Smoking, Tobacco, Smoking
GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments
The purpose of the study is to learn more about the relationships between the brain, behavior, and natural daily exposure to particular environments, including the places where smokers regularly spend time and specific retail…
- Conditions
- Smoking, Tobacco, Smoking, Smoking, Cigarette
- Trial name
- NCT04279483
- Testing
- Tobacco retailer, Non-tobacco retailer
- Where
- United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Sars-CoV2
Longitudinal Study of Covid-19 Infection Among HCW in a French University Hospital
The aim of the study is to determine the incidence o of SARS-cov2 infection among health care workers highly exposed to covid 19 during 10 weeks et to analyze the determinants of their occupational and environmental exposure.
- Trial name
- PRECOVIA (NCT04362267)
- Testing
- self-administered questionnaire, SARS-Cov2 testing
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Prostate Cancer, Leukemia
Natural History Study of Early Life Exposures in Agriculture (ELEA)
Study Description: ELEA is an observational cohort study that will collect exposure information and biospecimens from the adult children of the Agricultural Health Study (AHS) cohort (https://aghealth.nih.gov/about; Protocol…
- Conditions
- Prostate Cancer, Leukemia, Breast Cancer, Melanoma
- Trial name
- NCT07328516
- Where
- United States
- Volunteers
- 64,277 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Smoking, Passive Smoking
Prevent Exposure to Tobacco Smoke at Home [Gesunde Atemluft zu Hause]
Background: Infants are at risk for tobacco-attributable diseases by being exposed to environmental tobacco smoke (ETS). International literature has shown that a home smoking ban can reduce ETS.
- Conditions
- Smoking, Passive Smoking, Exposure to Environmental Smoke
- Trial name
- GESA (NCT00647413)
- Testing
- bio-chemical feedback and expert system intervention ETS
- Where
- Germany
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Nevi and Melanomas
Assessing Gene-Environment Interactions in Clinical Presentation of Nevi and Melanoma
This research study is designed to better understand the role of genetics, sun-exposure and phenotypic factors in melanoma.
- Trial name
- NCT03783325
- Testing
- UV Counseling, UV Photo, Biological Sample
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Breast Cancer
Studying The Association Between Environmental Exposure to PFAS and Breast Cancer in Assiut Governorate- Egypt
1. Measuring serum level of PFAS in breast cancer female patients and healthy participants. 2. Studying the correlation between serum level of PFAS and breast cancer risk through statistical modeling and analysis. 3.
- Trial name
- NCT06457282
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assiut University
Allergic Rhinitis, Rhinoconjunctivitis
Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects
To assess the reproducibility of the allergic response in the cat allergic subjects, measured as the change from baseline of the Total Nasal Symptom Score (TNSS) on the two challenge days.
- Conditions
- Allergic Rhinitis, Rhinoconjunctivitis, Exposure
- Trial name
- NEC (NCT03414801)
- Testing
- Allergen Exposure
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Red Maple Trials Inc.
Disease, Cardiovascular Diseases
Biomarkers of Acrylamide, Glycidol, POPs, PFAS and Disease Outcomes and OMICs Signatures
The aim of the project is to assess the associations between biomarkers of acrylamide and glycidol exposure and disease outcomes in a case-cohort study based on two prospective cohorts with biobanks.
- Conditions
- Disease, Cardiovascular Diseases, Cancer, Environmental Exposure
- Trial name
- NCT05930626
- Testing
- Biomarkers of acrylamide, glycidol, POPs, PFAS
- Volunteers
- 9,254 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Congenital Malformation
Pregnancy Environment and Newborn Malformations
Congenital malformations rate is about 3% in France. There are already 5 registries in France, covering about 16% of French births: Paris Registry, (about 38 000 births /year), Alsace Registry, (about 23 000 births/year)…
- Trial name
- PENEW (NCT01613638)
- Testing
- meconium samples + maternal self-questionnaire
- Where
- 11 sites in France
- Volunteers
- 1,657 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Cardiovascular Diseases
Novel Strategies for Reducing Heart Disease Risk Disparities
This Western Pennsylvania-based study will (1) improve cardiovascular risk stratification to identify high-risk populations, (2) identify differences in cardiovascular risk, (3) evaluate mechanisms for population differences in…
- Trial name
- HeartSCORE (NCT00143923)
- Testing
- Nutrition, Exercise, Stress Management Counseling, usual care
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Smoking, Healthy
Environments as Smoking Cues: Imaging Brain Substrates, Developing New Treatments (CameraCue)
The overarching goals of this proposal are to 1) identify the network of brain regions specifically activated by personal smoking environment cues and 2) to evaluate the effects of exposure to these cues on smoke…
- Trial name
- NCT01840111
- Testing
- Quit Smoking 6 hours, Quit Smoking 24 hours
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Duke University
Chronic Disease
Brief Interventions to Create Smoke-Free Home Policies in Low-Income Households: Texas Effectiveness Trial
The burden of tobacco use falls disproportionately on low-income populations, through high rates of primary smoking and exposure to secondhand smoke.
- Trial name
- SFH (NCT02097914)
- Testing
- Educational print materials and coaching call
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Congenital Heart Disease
Study on the Relationship Between Maternal Exposure to Environmental Factors and Fetal Congenital Heart Disease
The objective of this study is to research the relationship between maternal exposure to environmental factors and fetal congenital heart disease in a community-based case-control study.
- Trial name
- NCT02914392
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Diabetes, Heart Disease
Environmental Polymorphisms Registry Health and Exposures Survey
The Environmental Polymorphisms Registry (EPR) Health and Exposure Survey is designed to gather health, family history of disease, environmental exposures and lifestyle data on adult EPR subjects.
- Conditions
- Diabetes, Heart Disease, Asthma
- Trial name
- NCT01688986
- Where
- United States
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Infertility
Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes
The purpose of the study is to investigate the relationship between environmental agents and reproductive health. Environmental agents of interest include exposure to chemicals such as polychlorinated biphenyls (PCBs), flame…
- Trial name
- EARTH (NCT00011713)
- Testing
- Completion questionnaires/providing biological samples
- Where
- United States
- Volunteers
- 1,474 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pollution; Exposure, Glucose Intolerance
Environmental Toxicants Avoidance Study
This study is designed to test whether non-persistent environmental chemicals (PECs) are elevated in people with glucose dysregulation.
- Conditions
- Pollution; Exposure, Glucose Intolerance, Glycemic Control
- Trial name
- NPETA-GD (NCT04821752)
- Testing
- Avoidance Education
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Pulmonary Function
Service and Health Among Deployed Veterans
The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), or Operation New Dawn (OND) and other…
- Trial name
- SHADE (NCT02825654)
- Where
- 6 sites in United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Exposure to Environmental Pollution, Non-occupational
The Interaction of Social Factors With Air Pollution
Purpose: The purpose of this protocol is to understand how social factors such as psychosocial stress may modify how people respond to air pollution.
- Trial name
- SOZIAL (NCT02206750)
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Exposure to Pollution
Chemometers to Determine the Environmental and Human Exposome by Mixtures of Pollutants
Motivation of this study Human life is full of chemicals: They support the provision of cure, clothes, shelter, transportation and even nourishment of the world population.
- Trial name
- EXPOSO-METER (NCT05927077)
- Testing
- planned surgery for weight reduction
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Helmholtz Centre for Environmental Research - UFZ
Nasal Allergies, Allergies
Safety and Efficacy of AL-53817 Nasal Spray Solution
The purpose of this study was to determine the maximum tolerated dose of AL-53817 (Stage A) and evaluate the safety and efficacy of AL-53817 for the treatment of allergic rhinitis (Stage B).
- Trial name
- NCT01454505
- Testing
- AL-53817 nasal spray solution, Vehicle nasal spray
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alcon Research