Clinical trials: Entrapment Neuropathy
Carpal Tunnel Syndrome
Mechanisms of Neural Mobilization in the Treatment of Chronic Pain
The purpose of this study was to determine the effect of a manual therapy technique (neural mobilization) on measures of clinical pain and function, experimental pain sensitivity, and on the function of the median nerve in…
- Trial name
- NCT00929123
- Testing
- neural mobilization, healthy controls
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Charcot-Marie-Tooth, CMT1A
Studying Nerve Function and Structure in Charcot-Marie-Tooth Disease, Anti-MAG Neuropathy and CIDP
The project aims to perform both conventional nerve-conduction studies and axonal-excitability assessments using the TRONDF protocol in patients with selected forms of Charcot-Marie-Tooth disease, with comparison to individuals…
- Conditions
- Charcot-Marie-Tooth, CMT1A, Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Polyneuropathy Associated With Anti-MAG Antibodies (Anti-MAG Polyneuropathy)
- Trial name
- CMT-NFS (NCT07461896)
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Charcot-Marie-Tooth Disease, Type Ia
High Dose Ascorbic Acid Treatment of CMT1A
This study will look at the impact of ascorbic acid (Vitamin C) on the progression of disease in people with CMT1A as compared to volunteers receiving a placebo.
- Trial name
- NCT00484510
- Testing
- Ascorbic acid (Vitamin C)
- Where
- 3 sites in United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Carpal Tunnel Syndrome
Comparison of %5 Dextrose and Betamethasone Injections in Patients With Carpal Tunnel Syndrome
The aim of the study is to compare the effectiveness of ultrasound-guided betamethasone and 5% dextrose injection, which is routinely applied in clinical practice, in patients with mild and moderate carpal tunnel syndrome (CTS).
- Trial name
- NCT06360510
- Testing
- %5 dextrose injection, betamethasone injection
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Piriformis Syndrome, Corticosteroid Injection
Effect of Ultrasound-guided Piriformis Muscle Corticosteroid Injection Versus Extracorporeal Shock Wave Therapy for Piriformis Syndrome: a Randomized Control Trial
In this study, the investigators aim to compare the effect of extracorporeal shockwave therapy with ultrasound-guided piriformis coticosteroid injection in treatment of PS.
- Conditions
- Piriformis Syndrome, Corticosteroid Injection, Extracorporeal Shockwave Therapy, Therapeutic Exercise
- Trial name
- NCT04684537
- Testing
- Extracorporeal shockwave therapy (ESWT), Ultrasound-guided piriformis steroid injection
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Bardet Biedl Syndrome (BBS), Alström Syndrome (AS)
Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity
This pivotal, phase 3 study is designed to confirm the efficacy and safety of setmelanotide, a potent melanocortin receptor type 4 (MC4R) agonist, for the treatment of obesity and hyperphagia in participants with Bardet Biedl…
- Trial name
- NCT03746522
- Testing
- Setmelanotide
- Where
- 12 sites in United States, Canada and 4 more
- Volunteers
- 52 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Carpal Tunnel Syndrome (CTS)
Photobiomodulation for Median Nerve Neuroplasticity in Carpal Tunnel Syndrome: A Randomized Controlled Trial
Carpal Tunnel Syndrome (CTS) is the most common peripheral entrapment neuropathy, causing pain, paresthesia, and hand dysfunction due to median nerve compression at the wrist.
- Trial name
- PBM-CTS-RCT (NCT07714720)
- Testing
- Photobiomodulation (Low-Level Laser Therapy), Routine Physiotherapy Programme
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Lahore
Carpal Tunnel Syndrome, Entrapment Neuropathy
High Intensity Laser Therapy in Carpal Tunnel Syndrome
This research aims to investigate the effect of high-intensity laser therapy on pain, function, nerve conduction studies and grip strength in patients with idiopathic carpal tunnel syndrome.
- Conditions
- Carpal Tunnel Syndrome, Entrapment Neuropathy, Median Neuropathy, Musculoskeletal Diseases
- Trial name
- NCT04949373
- Testing
- High-intensity laser therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Hereditary Spastic Paraplegia
STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies
Our goal is to create a solid and harmonious disease registry of patient affected by hereditary spastic paraplegia (HSP) that facilitates the collection and management of patients' data over time encouraging the research and the…
- Trial name
- NCT06572046
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS Fondazione Stella Maris
Piriformis Syndrome
Kinesio Taping Technique and Trigger Point
Kinesio taping is a novel method which recently has emerged as a viable option to treat of various musculoskeletal and neuromuscular deficits.
- Trial name
- KT (NCT01752179)
- Testing
- kinesio Tape : Width 5cm ,Length 35cm Y shape
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Carpal Tunnel Syndromes
The Role of the Cervical Spine in Carpal Tunnel Syndrome
This randomized clinical trial will investigate changes in hand function, active cervical range of motion and pinch grip force after the application of physical therapy in women with carpal tunnel syndrome (CTS).
- Trial name
- NCT02233660
- Testing
- Physical Therapy Group, Surgical Group
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome: Diagnosis and Treatment Trial
The Carpal Tunnel Syndrome Diagnosis and Treatment Trial is project #1 of the Multidisciplinary Clinical Research Center focused on upper extremity pain.
- Trial name
- NCT00032227
- Testing
- Early Carpal Tunnel Release for Mild or Moderate CTS, MR Nerve Imaging for CTS
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Washington