Clinical trials: Entrapment Neuropathy
Carpal Tunnel Syndrome
The Effect of Carpal Tunnel Syndrome Phenotyping on Response to Treatment
The aim of this study was to evaluate the effect of Carpal Tunnel Syndrome (CTS) phenotyping on responsiveness to clinical interventions in individuals with CTS.
- Trial name
- NCT07754708
- Testing
- Standard Rehabilitation Protocol
- Volunteers
- 50 people
- Sponsor
- Kutahya Health Sciences University
Carpal Tunnel, Carpal Tunnel Syndrome
Comparing Superficial vs. Deep Local Anesthetic Infiltration to Improve Patient Experience During Carpal Tunnel Release
Hypothesis: When comparing superficial infiltration of local anesthetic to superficial and deep infiltration of local anesthetic in the setting of carpal tunnel release, the null hypothesis is that there will be no significant…
- Trial name
- NCT04201652
- Testing
- Superficial local anesthetic infiltration, Deep local anesthetic infiltration
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- University of Saskatchewan
Inclusion Body Myositis, Myotonic Dystrophy
Development and Validation of the FBIndex to Determine the Risk of Falls for Patients With Neuromuscular Disorders
Currently, there are no standardised fall risk scores or guidelines on when to use appropriate assistive gait devices (AGDs) for people with neuromuscular disorders (NMDs).
- Conditions
- Inclusion Body Myositis, Myotonic Dystrophy, Limb-girdle and Facioscapulohumeral Muscular Dystrophies, Pompe Disease
- Trial name
- FBIndex (NCT06605612)
- Testing
- FBIndex
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- LMU Klinikum
Median Nerve Entrapment, Carpal Tunnel Syndrome
Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome
The purpose of this study is to examine: 1. The effect of neurodynamic mobilization on the sensory and motor median nerve conduction velocity in carpal tunnel syndrome. 2.
- Trial name
- NCT05788471
- Testing
- conventional Treatment, Neurodynamic mobilization
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carpal Tunnel Syndrome (CTS), Glucocorticoid
Glucocorticoid, Ozone and 5% Dextrose Local Injection for Pain Relief in Carpal Tunnel Syndrome
This study aims to compare the efficacy and outcomes of perineural injection with 5% dextrose, local ozone and glucocorticoid injection in the management of carpal tunnel syndrome.
- Conditions
- Carpal Tunnel Syndrome (CTS), Glucocorticoid, Pain, Dextrose
- Trial name
- NCT07498998
- Testing
- Perineural injection with 5% dextrose (D5W)., Local ozone injection, Local glucocorticoid injection (dexamethasone).
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Piriformis Syndrome
Effects of Global Hip Versus Isolated Abductors Strengthening Exercises in Patients Withsecondary Piriformis Syndrome
The study will be a randomized controlled trial. Twenty-four subjects will be assigned randomly by using the lottery method into two groups.
- Trial name
- NCT05848063
- Testing
- Global hip muscles strengthening exercises, Hip abductors strengthening exercises
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Peroneal Nerve Entrapment
Follow-up and Outcome of Operative Treatment With Decompressive Release Of The Peroneal Nerve
The FOOT DROP trial is a prospective, multi-center, randomized controlled trial to assess if decompressive surgery for peroneal nerve entrapment is superior to maximal conservative treatment.
- Trial name
- FOOTDROP (NCT04695834)
- Testing
- Neurolysis peroneal nerve, Maximal physiotherapy
- Where
- 18 sites in Belgium, Netherlands
- Volunteers
- 182 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hereditary Spastic Paraplegia
A Prospective Cohort Study of ITB Treatment for HSP
The investigators conduct a prospective cohort study to explore the treatment effectiveness of continuous infusion of intrathecal baclofen (ITB) for hereditary spastic paraplegia (HSP) in China, delve into the optimal timing for…
- Trial name
- ITB-HSP (NCT06844734)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai 6th People's Hospital
Carpal Tunnel Syndrome, Depressive Symptoms
The Relationship of Psychological Factors and Sleep Quality With the Severity of Carpal Tunnel Syndrome
The most common entrapment neuropathy symptoms, the diagnosis of CTS, is determined by examination findings and by means of the results of electro-diagnostic test.
- Conditions
- Carpal Tunnel Syndrome, Depressive Symptoms, Sleepiness, Anxiety
- Trial name
- NCT05047367
- Testing
- cross-sectional survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people
- Sponsor
- Cumhuriyet University
Carpal Tunnel Syndrome (CTS)
Efficacy And Tolerability Of Alpha Lipoic Acid And Vitamin B Preparation In Carpal Tunnel Syndrome
The goal of this clinical trial is to assess the effectiveness and safety of an oral combination of alpha lipoic acid (ALA) and vitamin B complex in treating mild to moderate carpal tunnel syndrome (CTS) in adults.
- Trial name
- NCT06940557
- Testing
- Bionerv
- Where
- Malaysia
- Volunteers
- 70 people
- Sponsor
- Universiti Putra Malaysia
Duchenne Muscular Dystrophy, Fascioscapulohumeral Muscular Dystrophy
Assessments in Patients With Muscular Pathology and in Control Subjects : The ActiLiège Next Study
The objective of the ActiLiège Next study is to collect longitudinal data from patients and control subjects using a wearable magneto-inertial device.
- Conditions
- Duchenne Muscular Dystrophy, Fascioscapulohumeral Muscular Dystrophy, Myotonic Dystrophy 1, Charcot-Marie-Tooth
- Trial name
- NCT05982119
- Testing
- ActiMyo/Syde
- Where
- 8 sites in Belgium, Czechia and 5 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Carpal Tunnel Syndrome, Psoriatic Arthritis
Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis
This study aimed to investigate median nerve hypervasculatitation in psoriatic arthritis (PsA) patients with CTS or without CTS by using SMI, then compare them with normal people.
- Trial name
- NCT05086029
- Testing
- Superb Microvascular Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Lymphedema
Effect Of Complete Decongestive Therapy On Carpal Tunnel Syndrome Post Upper Limb Lymphedema
this study will be conducted to investigate the therapeutic effect of complete decongestive therapy on carpal tunnel syndrome post-upper limb lymphedema.
- Trial name
- CDT (NCT05932381)
- Testing
- Complete decongestive therapy, Medical treatment
- Volunteers
- 60 people
- Sponsor
- Cairo University
Trapeziometacarpal Arthrosis, Carpal Tunnel Syndrome
A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome
The investigators plan a prospective randomized controlled study that compares the treatment decisions made by patients who receive decision aids, as compared to patients treated with usual care and the American Society for…
- Conditions
- Trapeziometacarpal Arthrosis, Carpal Tunnel Syndrome, Cubital Tunnel Syndrome, Distal Radius Fractures
- Trial name
- NCT01693094
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Massachusetts General Hospital
Hereditary Spastic Paraplegia
Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia
Hereditary spastic paraplegias constitute a heterogeneous group of diseases with the common predominant feature of spasticity of the lower limbs.
- Trial name
- SPASTOX (NCT02604186)
- Testing
- Botulinum Toxin Injections
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Campinas, Brazil
Piriformis Syndrome
Comparative Effects of PIR and PFS on Pain, Hip ROM, and Disability in Piriformis Syndrome
This randomized clinical trial evaluates the effectiveness of Post-Isometric Relaxation (PIR) and Post-Facilitation Stretching (PFS) for managing pain, improving hip abduction and internal rotation, and enhancing functional…
- Trial name
- PIR-PFS RCT (NCT07255053)
- Testing
- Post Isometric Relaxation (PIR), Post Facilitation Stretching (PFS)
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Faisalabad
CTS, Carpal Tunnel Syndrome (CTS)
Comparative Efficacy of Neuromobilization, Tendon Gliding Exercises, and Combined Techniques in Mild to Moderate Carpal Tunnel Syndrome
focuses on the comparative efficacy of Neuromobilization techniques, tendon gliding exercises, and their combined application in the management of mild to moderate Carpal Tunnel Syndrome through a randomized controlled trial (RCT)
- Trial name
- NCT07653789
- Testing
- Combined Intervention Group, Neuromobilization Group, Tendon Gliding Exercise Group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ibadat International University, Islamabad
Amyotrophic Lateral Sclerosis (ALS)
Developing New Ways to Detect Respiratory Impairment Early in ALS
The goal of this observational study is to develop new ways to detect early changes associated with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
- Trial name
- NCT07844590
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Carpal Tunnel Syndrome, Peripheral Neuropathies
Effect of Exercise on Ultrasound SWV in CTS Patients
Carpal tunnel syndrome (CTS) is the most common peripheral neuropathy, and studies suggest exercises can be used for symptom management.
- Trial name
- NCT07281573
- Testing
- Nerve and tendon gliding exercises and strength exercises
- Where
- Slovenia
- Volunteers
- 91 people
- Sponsor
- University Medical Centre Ljubljana
Charcot-Marie-Tooth Disease Type 1A
Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT)
The purpose of this study is to determine whether PXT3003 is effective and safe in the treatment of Charcot-Marie-Tooth disease - Type 1 A (CMT1A).
- Trial name
- PLEO-CMT (NCT02579759)
- Testing
- PXT3003 dose 1, PXT3003 dose 2
- Where
- 30 sites in United States, Belgium and 6 more
- Volunteers
- 323 people
- Sponsor
- Pharnext S.C.A.