Clinical trials: Enteral Feeding Intolerance
Very Preterm Maturity of Infant, Enteral Feeding Intolerance
Early Total Enteral Feeding Versus Convention Enteral Feeding in Preterm Infants 27-32 Weeks of Gestation
The objective of the study is to compare the time of attainment of full enteral feeds in preterm neonates between 27-32 weeks of gestation started on early total enteral feeding (ETEF) with those started on conventional enteral…
- Trial name
- ETEFVsCEF (NCT06076460)
- Testing
- Early Total Enteral Feeding, Conventional Enteral Feeding
- Where
- India
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Lady Hardinge Medical College
Enteral Feeding Intolerance
Bedside Observation by Clinical Ultrasound for Stomach Expansion
The objective of the BOCUSE study is to demonstrate a relationship between an early ultrasound measurement of the gastric antral area and the subsequent occurrence of poor gastric tolerance.
- Trial name
- BOCUSE (NCT07312890)
- Testing
- Gastric ultrasound with measurement of the antral area
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Feeding, ICU
mNEED: a Multicentre, Cluster-randomized, Controlled Trial
Project Name: Improved Feeding Regimen for Critically Ill Patients (mNEED) Based on Feeding Intolerance Prediction Model Solution version number and version date: Version 5.0; 2024.12.16 Informed consent version number and…
- Trial name
- mNEED (NCT06827275)
- Testing
- Feeding process
- Where
- 2 sites in China
- Volunteers
- 2,250 people
- Sponsor
- The First Hospital of Jilin University
Feeding Intolerance, Necrotizing Enterocolitis
Bovine Colostrum as a Human Milk Fortifier for Preterm Infants
Very preterm infants (<32 weeks gestation) show the immaturity of organs and have high nutrient requirements for growth and development.
- Conditions
- Feeding Intolerance, Necrotizing Enterocolitis, Postnatal Growth, Late-Onset Neonatal Sepsis
- Trial name
- FortiColos-Ⅱ (NCT03822104)
- Testing
- Bovine Colostrum, FM85
- Where
- 2 sites in China
- Volunteers
- 139 people
- Sponsor
- Per Torp Sangild
Children Requiring Amino Acid-based Formula Tube Feeding, Enteral Feeding Intolerance
Retrospective Review of Amino Acid Formula Use at a Children's Center
This is a retrospective review of data documented in medical records.
- Trial name
- NCT03497091
- Testing
- Enteral Formula
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Société des Produits Nestlé (SPN)
Critical Illness, Organ Dysfunction
The Effect of the Timing of Supplemental Parenteral Nutrition on the Prognosis of Critically Ill Patients (T-SPN)
This multicenter, randomized controlled trial aims to evaluate whether early initiation of supplemental parenteral nutrition (SPN) (on day 4 of ICU admission) compared to late initiation (on day 8) can reduce 28-day all-cause…
- Conditions
- Critical Illness, Organ Dysfunction, Enteral Nutrition Intolerance, Inadequate Nutritional Intake
- Trial name
- NCT07085455
- Testing
- Early Supplemental Parenteral Nutrition (SPN), Late Supplemental Parenteral Nutrition (SPN)
- Where
- 2 sites in China
- Volunteers
- 946 people
- Sponsor
- Dong Zhang
Critical Illness, Enteral Nutrition Intolerance
Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients
This study aims to explore the correlation between gastrointestinal blood flow and the incidence of enteral nutrition intolerance (ENI) and its symptoms in critically ill patients, construct and compare predictive models…
- Conditions
- Critical Illness, Enteral Nutrition Intolerance, Enteral Nutrition Feeding, Prediction Models
- Trial name
- NCT07521111
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Enteral Nutrition
The Effect of FODMAP Content in Tube Feeding Formula on Feeding Intolerance and Nutritional Status Improvement
This study aimed to investigate the effects of FODMAP contents in enteral nutrition (EN) formulas on major gastrointestinal intolerance symptoms and nutritional status in tube fed patients through the randomized, double blind and…
- Trial name
- NCT02353689
- Testing
- low FODMAP, moderate FODMAP, high FODMAP
- Volunteers
- 84 people
- Sponsor
- Oh Yoen Kim
Mechanical Ventilation Complication, Enteral Feeding Intolerance
Gastric Ultrasound to Monitor Gastric Residual Volume
It is currently recommended to start enteral nutrition early in intensive care unit children receiving invasive or non-invasive mechanical ventilation.
- Trial name
- GASTRIPED (NCT04119089)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Hospices Civils de Lyon
Refractory Enteral Feeding Intolerance, Gut Microbiota
Gut Microbiota Structure, Functional and Metabolic Profiles, and Composite Biomarkers in ICU Adults With Refractory Enteral Feeding Intolerance
Some adults in the intensive care unit (ICU) cannot receive enough nutrition through a feeding tube because of persistent digestive problems, even after standard measures to improve feeding.
- Conditions
- Refractory Enteral Feeding Intolerance, Gut Microbiota, Metabolic Profiles
- Trial name
- NCT07864844
- Testing
- Naturally Occurring Exposures
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Pain, Stress
The Effect of Feeding Positions During Tube Feeding on Stress, Pain Level and Feeding Tolerance of Preterm Infants
Premature infants have a need for an orogastric or nasogastric feeding tube because of the immaturity of coordination between suck-swallow and breathing. Tube feeding could cause feeding intolerance and stress.
- Conditions
- Pain, Stress, Enteral Feeding Intolerance
- Trial name
- NCT04156529
- Testing
- ESU position, ESRL position
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Sibel Serap Ceylan
Gastroparesis, Shock
Gastric Emptying and Enteral Nutrition Tolerance According to Vasopressor Dose in ICU Patients
This study investigates whether the dose of vasopressor medications (drugs that maintain blood pressure in shock) affects gastric emptying during tube feeding in the intensive care unit (ICU).
- Conditions
- Gastroparesis, Shock, Critical Illness, Gastric Emptying
- Trial name
- NCT07802379
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Enteral Feeding Intolerance
A Comparative Evaluation of Mosapride Versus Metoclopramide for Enteral Feeding Intolerance in Critically Ill Patients
Caring for critically ill patients in an intensive care unit (ICU) is considered a standard of care. According to the Society of Critical Care Medicine (SCCM), as a function of the complex nature of the care provided in the ICU…
- Trial name
- NCT06826443
- Testing
- Mosapride Citrate Tablets, Metoclopramide 10mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Bone Marrow Disease, Stem Cell Transplant Complications
Tube Feeding in Children Having a Bone Marrow Transplant
The purpose of this study is to assess the problems and a range of nutritional and clinical outcomes that occur with two feeding tubes used by children having a bone marrow transplant.
- Conditions
- Bone Marrow Disease, Stem Cell Transplant Complications, Enteral Feeding Intolerance, Gastrostomy
- Trial name
- NCT04804631
- Testing
- Enteral feeding tubes
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Institute of Child Health
Acute Pancreatitis (AP), Enhancing Enteral Nutrition Tolerance
Evaluating RELiZORB Use for the Treatment of Feeding Intolerance in Adults With Moderate to Severe Acute Pancreatitis
The goal of this study is to learn if Relizorb, a fat-digesting enzyme, can improve tolerance of tube feeds in adult patients with moderate to severe pancreatitis.
- Trial name
- NCT07583342
- Testing
- RELiZORB digestive enzyme (immobilized lipase) cartridge
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Northwell Health
Critically-ill Patients
Itopride in Feeding Intolerance of Critically-ill Patients Receiving Enteral Nutrition
The current study will compare the effectiveness as well as the safety of Itopride against metoclopramide as the first line treatment for feeding intolerance in critically ill patients.
- Trial name
- NCT03698292
- Testing
- Itopride, Metoclopramide 10mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Enteral Nutrition, Feeding Intolerance
Evaluation of Status of Early Reached Target Enteral Nutrition and IFABP as Biomarker of Feeding Intolerance in Critically Ill Children
Stage 1 - Evaluation of Status of Early Reached Target Enteral Nutrition in critically ill children in the PICU (ERTEN in PICU).
- Conditions
- Enteral Nutrition, Feeding Intolerance, Intestinal Fatty Acid Binding Protein
- Trial name
- ERTENIFABPICU (NCT02598375)
- Testing
- Feeding intolerance
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Gazi University
Critically Ill Patients Who Are Not Allowed to Eat Orally But Can Initiate Enteral Nutrition Within 48 Hours of ICU
Association of Biomarkers and Gastric Antral Motility Index With Feeding Intolerance in Critically Ill Patients
When the subjects are admitted to the department, the researchers will monitor potential biomarkers of gastrointestinal injury before administering enteral nutrition (a small amount of blood is drawn, serum is separated by…
- Trial name
- NCT07178626
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First Hospital of Jilin University
Septic Shock
Splanchnic Perfusion Monitoring in Septic Shock Using Doppler Ultrasound
evaluation whether splanchnic Doppler ultrasound indices (SMA resistive index, portal vein pulsatility fraction, hepatic artery resistive index/flow parameters) can: 1.
- Trial name
- NCT07698834
- Volunteers
- 80 people
- Sponsor
- Assiut University
Preterm, Feeding Behavior
Feeding Readiness and Oral Feeding Success in Preterm Infants
To examine the effects of sensorimotor interventions applied to in preterm infants on readiness for feeding and oral feeding success.
- Conditions
- Preterm, Feeding Behavior, Enteral Feeding Intolerance
- Trial name
- NCT04946045
- Testing
- Sensorimotor Interventions (Tactile/Kinesthetic Stimulation+Nonnutritive Sucking)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University