Clinical trials: Enhanced Recovery, open to volunteers
Cesarean Section (MeSH: D002585), Postoperative Pain After Cesarean Section
Esketamine Combined With Transcutaneous Electrical Acupoint Stimulation on Postoperative Recovery Quality After Elective Cesarean Section
This study is a prospective randomized controlled trial aimed at evaluating whether the combination of esketamine and transcutaneous electrical acupoint stimulation (TEAS) can improve the quality of postoperative recovery in…
- Conditions
- Cesarean Section (MeSH: D002585), Postoperative Pain After Cesarean Section, Enhanced Recovery After Surgery
- Trial name
- NCT07916051
- Testing
- Esketamine, Active TEAS, Normal Saline
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Anesthesia
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block…
- Trial name
- EKAT-TeleTPS (NCT03747146)
- Testing
- Continuous Adductor Canal Catheter (ACC)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Chronic Musculoskeletal Pain
This Project is a Three-arm RCT Evaluating Two, Single-session Behavioral Interventions for Adults With Chronic Musculoskeletal Pain (CMP) -- 1) Brief Mindfulness-Oriented Recovery Enhancement (B-MORE) vs. Empowered Relief (ER) -- Relative to the Traditional 8-week Version of MORE.
Researchers at Florida State University are investigating how the length of treatment influences outcomes for individuals with chronic musculoskeletal pain.
- Trial name
- Brief Relief (NCT07193095)
- Testing
- Brief Mindfulness Oriented Recovery Enhancement, Empowered Relief, Mindfulness Oriented Recovery Enhancement
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Florida State University
Postoperative, Pain
Effect of Erector Spinae (ESP) Block on Opioid Reduction and Enhanced Recovery After Posterior Cervical Spine Surgery
Patients undergoing spine surgery frequently experience significant pain after surgery. This can limit patient activity and hinder rehabilitation.
- Trial name
- NCT04646707
- Testing
- Erector Spinae (ESP) Block with Lidocaine/Bupivacaine
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Postoperative Cognitive Dysfunction, Postoperative Recovery
Older People's Neurocognitive Recovery After Cardiac Surgery
Society is aging and advantages in anesthesia and surgery allow more complex interventions in older persons. Old age is a significant risk factor for the development of postoperative neurocognitive decline characterized by a…
- Conditions
- Postoperative Cognitive Dysfunction, Postoperative Recovery, Cardiac Surgery
- Trial name
- ECPON (NCT06469515)
- Testing
- Elective or urgent cardiac surgery
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
Lumbosacral Radiculopathy, Sciatica
A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE
The Move-MORE study is designed to evaluate a multicomponent mindfulness and movement program for patients with lumbosacral radiculopathy.
- Conditions
- Lumbosacral Radiculopathy, Sciatica, Chronic Low Back Pain With a Neuropathic Component, Radiculopathy Lumbar
- Trial name
- Move-MORE (NCT07125027)
- Testing
- Move-MORE
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National University of Natural Medicine
Cholecystitis, Acute, Cholecystectomy, Laparoscopic
Implementation of RICA (ERAS) Guidelines in Grade II Acute Cholecystitis Undergoing Early Laparoscopic Cholecystectomy
Background Acute cholecystitis (sudden gallbladder inflammation, usually due to gallstones) is a highly frequent surgical emergency.
- Conditions
- Cholecystitis, Acute, Cholecystectomy, Laparoscopic, Enhanced Recovery After Surgery
- Trial name
- COLERICA II (NCT07695922)
- Testing
- RICA Perioperative Care Pathway
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital d'Igualada
Lung Cancer, Surgery
Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery
Objective: The adoption of Enhanced Recovery Surgery programs in lung resection is relatively recent with limited outcome data. This study aimed to determine the impact of an Enhanced Recovery Surgery pathway on short- term and…
- Conditions
- Lung Cancer, Surgery, ERAS
- Trial name
- NCT04451473
- Testing
- Enhanced Recovery After Surgery (ERAS ), Traditional perioperative management without Enhanced Recovery After Surgery (ERAS )
- Where
- China
- Volunteers
- 350 people
- Sponsor
- The Second Hospital of Shandong University
Postoperative Pain Following Knee Arthroplasty
Evaluating Suzetrigine for Pain Control Following TKA
The goal of this clinical trial is to learn if a non-opioid pain medicine called suzetrigine works to treat pain after total knee replacement surgery in adults. It will also learn about the safety of suzetrigine.
- Trial name
- NCT07357376
- Testing
- Suzetrigine
- Volunteers
- 210 people
- Sponsor
- AdventHealth
End-stage Lung Disease
Perioperative Recovery Outcomes of a Spontaneous Breathing-Preserving Strategy in Salvage Lung Transplantation
The goal of this prospective, multicenter, single-arm clinical study is to learn whether a breathing-preserved anesthesia-surgical strategy can improve early recovery and perioperative survival in adults undergoing rescue/bridge…
- Trial name
- NCT07384533
- Testing
- Lung transplantation that preserves spontaneous breathing function
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Pelvic Organ Prolapse (POP), Postoperative Pain
Effect of Paracervical Block on Postoperative Pain After vNOTES Uterosacral Ligament Suspension
This study is a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effect of paracervical block on early postoperative pain after vaginal natural orifice transluminal endoscopic…
- Trial name
- vNOTES-PB (NCT07440576)
- Testing
- Bupivacaine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Erkan Gol
Video-assisted Thoracoscopic Surgery (VATS), Postoperative Pain
Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Video-assisted Thoracoscopic Pneumonectomy
Revised-Paravertebral Nerve Block (r-PVB) is performed right after induction of general anesthesia and before lateral positioning of surgery.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Postoperative Pain, Quality of Recovery, Lung Diseases
- Trial name
- r-PVB-1 (NCT07567950)
- Testing
- Revised-Paravertebral Nerve Block, Control
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Postoperative Complication, Respiratory Complications
Real-time Evaluation and Continuous Observation of Vital Signs for Enhanced Recovery: a Study for the Early Identification of Complications in the Surgical Ward Following Surgery in Patients Not Eligible for Intensive Care Admission.
This study aims to evaluate whether continuous vital sign monitoring with wearable devices can help detect postoperative complications in surgical ward earlier than standard hospital monitoring.
- Conditions
- Postoperative Complication, Respiratory Complications, Cardiac Complications
- Trial name
- RECOVER (NCT07729891)
- Testing
- Continuous vital sign monitoring with Portrait Mobile in surgical ward
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Postoperative Care, Postoperative Complications
Nutrition to Support Postoperative Recovery
Older surgical patients commonly have malnutrition, and there is evidence these patients have increased risk for poor physical and brain recovery after surgery and anesthesia.
- Conditions
- Postoperative Care, Postoperative Complications, Cognition, Nutritional Assessment
- Trial name
- NCT07109505
- Testing
- Nutritional Shake, Nutritional Instructions Only
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Benign Gallbladder Disease, Laparoscopic Cholecystectomy
Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Laparoscopic Cholecystectomy
After laparoscopic cholecystectomy, pain remains an important problem affecting patient recovery. A revised paravertebral block (r-PVB) was developed as a single-shot, large-volume intercostal-space injection performed at the…
- Conditions
- Benign Gallbladder Disease, Laparoscopic Cholecystectomy, Postoperative Pain, Quality of Recovery
- Trial name
- REVISED-PVB II (NCT07566819)
- Testing
- Revised-Paravertebral Nerve Block
- Volunteers
- 250 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Enhanced Recovery After Anesthesia
Intraoperative Lidocaine Infusion
This study aims to evaluate the analgesic and anti-inflammatory effect of perioperative intravenous lidocaine infusion and in turn the return of gastric motility in patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- IV (NCT07150481)
- Testing
- IV Lidocaine infusion, IV normal saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Thyroid Diseases, Ambulation Time
Comparison of Post-operative Outcomes Between ERAS Protocol and Non-ERAS Local Regimen in Patients Undergoing Thyroidectomy
Patients undergoing thyroidectomy in hospital setup will be compared by applying ERAS protocol to one group and non ERAS local regimen to other group.
- Conditions
- Thyroid Diseases, Ambulation Time, Hospital Stay
- Trial name
- NCT07915960
- Testing
- ERAS protocol, Non ERAS local regimen
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Allied Hospital Faisalabad
Female, Male
Towards a Sex-specific "Female Enhanced Recovery After Cardiac Surgery'' (F-ERAS) Pathway:
The aim of this study is to evaluate the differences between men and women undergoing cardiac surgery. We will look at perioperative factors such as body weight, body surface area, previous medical history, pharmacokinetics…
- Conditions
- Female, Male, Surgery,Cardiac
- Trial name
- F-ERAS (NCT06175650)
- Testing
- Cardiac surgery
- Where
- Netherlands
- Volunteers
- 5,500 people
- Sponsor
- Jennifer Breel
Postoperative Ileus, Delayed Gastrointestinal Motility
Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients
Postoperative ileus (POI) is a frequent complication after abdominal surgery, leading to delayed gastrointestinal motility, prolonged hospital stay, and increased patient discomfort.
- Conditions
- Postoperative Ileus, Delayed Gastrointestinal Motility, Postoperative Gut Dysfunction
- Trial name
- NCT07425249
- Testing
- Chewing Gum
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Khyber Medical University Peshawar
Lung Surgery, Enhanced Recovery After Surgery, ERAS
Evaluation of the Effectiveness of Enhanced Recovery After Surgery (ERAS) Program in Pediatric Lung Surgery
This study aims to evaluate the clinical effectiveness of the Enhanced Recovery After Surgery (ERAS) program for pediatric lung surgery at our institution.
- Conditions
- Lung Surgery, Enhanced Recovery After Surgery, ERAS, Pediatric
- Trial name
- NCT07241286
- Testing
- Enhanced Recovery After Surgery, ERAS
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital