Clinical trials: Enhanced Recovery
Opioid Free Anesthesia
Intraoperative Retrolaminar Block as Opioid Free Anesthesia After Posterior Lumber Spine Discectomy
Opioid-free intraoperative protocols have been successfully used in specific surgical populations with equal or superior results to classic general anesthetic approaches.
- Trial name
- NCT05312866
- Testing
- Standard analgesia (paracetamol +fentanyl), Retrolaminar block with bupivacaine + magnesium sulfate + dexamethasone
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Zagazig University
ICU Survivors
Integrated Recovery Program for Critical Illness
This study aims to investigate the effects of the Integrated Critical Illness Aftercare and Recovery Enhancement (I-CARE) program on reducing healthcare burden and improving functional outcomes in ICU survivors.
- Trial name
- iCARE (NCT06997822)
- Testing
- LINE Bot-Based Remote Care Combined with In-Person Post-ICU Clinic
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- National Taiwan University Hospital
Total Knee Arthroplasty, Knee Osteoarthritis
Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty
The purpose of this study is to assess the effectivity of adductor canal block performed the day after total knee arthroplasty surgery in reducing pain and improving walking ambulation ability and muscle strength.
- Trial name
- NCT03915522
- Testing
- Single adductor canal block, Simulated adductor canal block
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Colorectal Cancer, Nutritional Deficiency
PeRioperative Omega Three and the Effect on ImmuNity
Bowel cancer is the second most common cause of cancer-related death in the UK, with 50,000 new cases and over 15,000 deaths annually.
- Conditions
- Colorectal Cancer, Nutritional Deficiency, Infected Wound, Surgical Site Infection
- Trial name
- PROTEIN (NCT03598413)
- Testing
- Omega-3
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Ileus
Intermountain Healthcare's Enhanced Recovery Protocol for Colon Surgery With and Without Alvimopan Use
The purpose of this study is to determine if the addition of alvimopan to our care process model for colon resection patients will decrease length of stay.
- Trial name
- NCT01143259
- Testing
- Alvimopam, 300 mg Polyethylene
- Where
- 9 sites in United States
- Volunteers
- 274 people
- Sponsor
- Intermountain Health Care, Inc.
Postoperative Pain, Laparoscopic Cholecystectomy
Erector Spinae Plane Block and Low-Flow Anaesthesia in Laparoscopic Cholecystectomy
This prospective randomized controlled study aims to evaluate the effects of preoperative ultrasound-guided erector spinae plane (ESP) block combined with low-flow anaesthesia on postoperative quality of recovery and opioid…
- Trial name
- NCT07653490
- Testing
- Erector Spinae Plane Block, Low Fresh Gas Flow (0.5 L/min), Standard Fresh Gas Flow (3 L/min)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Postoperative Pain, Opioid Use
Continuous Serratus Anterior Blockade for Sternotomy
This is a pilot study to assess the feasibility of a full study. The purpose is to assess the analgesic effectiveness of the serratus anterior plane (SAP) block following cardiac surgery.
- Conditions
- Postoperative Pain, Opioid Use, Quality of Life
- Trial name
- Cardiac-SAP (NCT04648774)
- Testing
- Serratus anterior plane (SAP) block
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Colorectal Surgery
Evaluation of a Preoperative Education Class for Colorectal Surgery Patients
The purpose of the study is to evaluate the value and effectiveness of a newly-implemented preoperative education class for patients undergoing colorectal surgery.
- Trial name
- NCT03237897
- Testing
- Preoperative education class, Pedometer
- Sponsor
- Wake Forest University Health Sciences
Traumatic Brain Injury (Tbi), Traumatic Meningeal Enhancement (Tme)
Imaging Characterization of the Biomechanical Coupling of Brain and Skull
Background: Traumatic brain injury (TBI) affects over 1.7 million people in the United States each year. Many cases are mild, but people with a history of TBI may have long-term symptoms; they are also known to be more…
- Trial name
- NCT05675423
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Stroke
GoHand(TM) to Enhance Recovery of Arm and Hand Function Post-Stroke
This is a proof-of-concept study aimed at contributing evidence towards the need, usability and efficacy potential of the GoHandTM sensor in people with reduced hand function post-stroke.
- Trial name
- GoHand (NCT05321446)
- Testing
- GoHand(TM)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- McGill University
Head and Neck Cancer
Optimising Microsurgical Reconstruction After Advanced Head and Neck Cancers
This study aims to improve the peri- and postoperative care regimen for patients undergoing microvascular reconstruction after head and neck cancer by introducing an enhanced recovery after surgery (ERAS) programme.
- Trial name
- NCT04308525
- Testing
- Early ambulation, Early oral feeding, Multimodal opioid-sparing analgesia
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Enhanced Recovery After Surgery, Cystectomy
Study of the Quality of Life of Patients Treated by Heavy Surgery as Part of an Enhanced Recovery at Beau Soleil Clinic- QUALICHIR
Heavy and oncological surgery is undergoing a major evolution. Some surgical dogmas are falling and care is better rationalized.
- Trial name
- QUALICHIR (NCT04028934)
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Clinique Beau Soleil
Ventilator-Induced Diaphragm Dysfunction
Study of TransAeris® System for Enhanced Recovery After Surgery in France
This study will be conducted as a randomized trial of the TransAeris system for the prevention and treatment of ventilator-induced diaphragm dysfunction (VIDD) in patients identified prior to surgery to be at greater risk of…
- Trial name
- ERAS (NCT05404477)
- Testing
- TransAeris System
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Synapse Biomedical
Osteoarthritis
Does Intraoperative Intravenous Iron Enhance Postoperative Oxygenation Profile in Total Knee Arthroplasty Surgery?
The objective of the present study is to determine the impact of intraoperative IV-iron supplementation on postoperative oxygenation profile by comparing the postoperative PaO2/FiO2 ratio with or without IV-iron supplementation…
- Trial name
- NCT02544464
- Testing
- ferric carboxymaltose 1000 mg
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Konkuk University Medical Center
Colorectal Disorders
A Mobile Device App to Improve Adherence to an Enhanced Recovery Program for Colorectal Surgery
A randomized control trial on patients undergoing laparoscopic colorectal resection in an Enhanced Recovery Program (ERP). The intervention is delivered via an electronic application containing guidelines, information, and…
- Trial name
- NCT03277053
- Testing
- Mobile application, Control.
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Dr. Liane S. Feldman
Stroke, Inpatients
A Novel Approach to Enhance True Recovery After Stroke
The purpose of this study is to elucidate pathophysiological mechanisms behind gait disturbances during the early recovery phase after hemiparetic stroke to identify targets for new treatment strategies.
- Conditions
- Stroke, Inpatients, Recovery of Function, Observational Study
- Trial name
- NCT05359367
- Testing
- Observational
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Danderyd Hospital
Cardiac Surgery, Opioid Use, Unspecified
Pecto-Intercostal Fascial Plane Block Study
This study is being done to see if bilateral pecto-intercostal fascial plane blocks (PIFB) with a mixture of liposomal and standard bupivacaine decrease pain and opioid requirements in patients undergoing cardiac surgery via…
- Trial name
- NCT04928339
- Testing
- Bupivacaine Injection, Liposomal bupivacaine, Saline
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Pelvic Floor Muscle Electrophysiologic Therapy, Fast-Track Surgery
Effect of Pelvic Floor Muscle Electrophysiologic Therapy on Enhanced Recovery After Gynecologic Surgery
This study is to evaluate the effect of pelvic floor muscle electrophysiologic therapy on enhanced recovery after gynecologic surgery,to solve muscle soreness and retention of urine after laparoscopy, and endometrial repair after…
- Trial name
- NCT03524807
- Testing
- Electrophysiologic therapy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Colorectal Cancer, Colorecatal Cancer Surgery
Enhanced Recovery After Surgery in Patients Undergoing Colorectal Cancer Surgery
This study compared an Enhanced Recovery After Surgery (ERAS) care program with conventional perioperative care in adults undergoing surgery for colorectal cancer.
- Trial name
- NCT07889934
- Testing
- Enhanced Recovery After Surgery (ERAS) Pathway, Conventional Perioperative Care
- Where
- Greece
- Volunteers
- 91 people
- Sponsor
- University of West Attica
Colon Cancer
Enhanced Recovery Program After Laparoscopic Colon Cancer Surgery
An enhanced recovery program has been developed to provide for colon cancer patients faster and more personalized postoperative treatment.
- Trial name
- NCT02399631
- Testing
- Enhanced recovery program
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Kyungpook National University Hospital