Clinical trials: Engagement
Ischemic Stroke
Community Engagement for Early Recognition and Immediate Action in Stroke
The investigators plan to develop and adapt a community-partnered intervention using community health promoters ("Stroke Promoters") to deliver messaging regarding stroke symptom awareness and the need for calling 911 after…
- Trial name
- CEERIAS (NCT02301299)
- Testing
- Community-based Stroke Awareness Program
- Where
- United States
- Volunteers
- 1,322 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Skin Cancer
Engaging Moms on Teen Indoor Tanning Through Social Media
A sample of mothers in Tennessee are recruited to a group-randomized pretest-posttest controlled trial evaluating the effect of a social media campaign to decrease mothers' permissiveness for daughters to indoor tan.
- Trial name
- NCT02835807
- Testing
- Health Chat including Indoor Tanning, Health Chat excluding Indoor Tanning
- Where
- 4 sites in United States
- Volunteers
- 1,607 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
ST Elevation Myocardial Infarction
CArdiac Brief INtervention: A Feasibility Study to Promote Engagement With Cardiac Rehabilitation
Background: An ST-elevation myocardial infarction (STEMI) is a specific type of heart attack. In a previous study, patients requested more mental and emotional support after a STEMI.
- Trial name
- CABIN (NCT05848674)
- Testing
- CArdiac Brief INtervention (CABIN), Refined version of CABIN
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Queen's University, Belfast
Hiv
Pharmacist-led Intervention for Injectable HIV Treatment for Women With Health-related Social Needs
This study addresses real-world use of long-acting injectable cabotegravir/rilpivirine (CAB/RPV LA) by evaluating implementation and clinical outcomes of a pharmacist-led collaborative drug therapy management model (CDTM+) that…
- Trial name
- NCT06411223
- Testing
- Collaborative drug therapy management model, Cabotegravir/Rilpivirine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Psychogenic Non-epileptic Seizures, Motivational Interviewing
Motivational Interviewing to Enhance Adherence of Patients With Psychogenic Non-epileptic Seizures
All subjects will attend an initial clinic visit with the neuropsychiatrist and epileptologist. At the end of this visit, those subjects randomized to motivational interviewing will be questioned using standardized motivational…
- Trial name
- NCT02598076
- Testing
- motivational interviewing, standard psychotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brigham and Women's Hospital
Parkinson's Disease
Terazosin And Metabolic Engagement in Parkinson's Disease
To assess target engagement of terazosin (TZ) at multiple doses (1 mg/day, 3 mg/day, and 5 mg/day) and to assess sustained target engagement over 6 months relative to placebo in patients with Parkinson's Disease (PD).
- Trial name
- TAME-PD (NCT07288450)
- Testing
- Terazosin Hydrochloride
- Sponsor
- Nandakumar Narayanan
Lymphomas Non-Hodgkin's B-Cell, Diffuse Large B-cell Lymphoma (DLBCL)
ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)
This Phase 1, single centre, open label dose escalation study aims to identify a safe dose of third-generation anti-CD19 CAR T-cells (WZTL-002) in the treatment of patients with relapsed or refractory (r/r) B-cell Non Hodgkin…
- Conditions
- Lymphomas Non-Hodgkin's B-Cell, Diffuse Large B-cell Lymphoma (DLBCL), Primary Mediastinal B-cell Lymphoma (PMBCL), Transformed Follicular Lymphoma (TFL)
- Trial name
- ENABLE-1 (NCT04049513)
- Testing
- WZTL002-1 (1928T2z CAR-T cells), Cyclophosphamide and Fludarabine lymphodepleting chemotherapy
- Where
- New Zealand
- Volunteers
- 30 people
- Sponsor
- Malaghan Institute of Medical Research
Healthy Lifestyle
Impact of Breathing Exercise Intervention on Breathing Sectors Engagement in Adolescent Runners During Load
Forty-six endurance runners, 23 males (age = 16.4±1.1) and 23 females (age=16.8±1.1) participated in our study. The contribution of abdominal, thoracic, and subclavian musculature to respiration and ventilation parameters during…
- Trial name
- breathing (NCT04950387)
- Testing
- Breathing exercises
- Where
- Czechia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of South Bohemia
Patient and Family Engagement
Family Procedural Presence
This study seeks to determine the effect of a quality improvement policy regarding allowing family members to remain in a patient's room during ICU procedures.
- Trial name
- NCT03808350
- Testing
- Families Invited to Be Present at Procedures
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Intermountain Health Care, Inc.
Patient Engagement, Patient Preference
Increasing Decision Quality for Men With Lower Urinary Tract Symptoms
In this study, the investigators show that by upskilling of primary care physicians (PCPs) in SDM and leveraging on a novel pictorial Visual Analogue Uroflowmetry Score (VAUS), they can enhance older men's recognition of LUTS and…
- Trial name
- NCT04851275
- Testing
- Physicians trained in shared decision making, Physicians were not trained in shared decision making
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SingHealth Polyclinics
Smoking Cessation
Latinos Kick Buts: Mobile Engagement and Cessation Support for Latino Smokers
Latino Kick Buts (LKB) is a smoking cessation treatment program available to patients identified as smokers at the University of Rochester Medical Center.
- Trial name
- NCT05278481
- Testing
- Reward Message with standard introduction, Reward Message with culturally tailored introduction, Threat/Self-efficacy with standard introduction
- Where
- United States
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Family Engagement
Improving Family Engagement in Acute Cardiovascular Care: The NGAGE Trial
The objective of this study is to assess if the NGAGE real-time feedback tool improves family engagement in family members of people admitted to an acute cardiac care unit The investigators will randomize 88 family members of…
- Trial name
- NGAGE (NCT05939427)
- Testing
- NGAGE tool
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Hypertension
Engaging Native Hawaiian/Pacific Islanders and Activating Communities to Take Steps (ENACTS)
Our Specific Aims are: 1. At the individual level, to compare within-person change in BP and secondary outcomes between the intervention and control groups. 2.
- Trial name
- ENACTS (NCT03484364)
- Testing
- ENACTS
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Washington State University
Improving Perceptions of HIV Risk, Improving Uptake of Pre-exposure Prophylaxis for HIV
Manicaland PrEP Uptake Through Interactive Counselling Trial
Primary Objective: The purpose of this trial is to evaluate the impact of an interactive tablet based counselling session correcting risk perception and addressing ambiguity around availability, usability and effectiveness of…
- Trial name
- NCT03565575
- Testing
- Interactive tablet-based quiz
- Where
- 8 sites in Zimbabwe
- Volunteers
- 1,055 people, healthy volunteers welcome
- Sponsor
- Simon Gregson
Neurodevelopmental Disorders
Evaluation of the Effectiveness of Child-oriented Goal-setting in Paediatric Rehabilitation (the ENGAGE Approach)
Children with disabilities often access rehabilitation services to improve their abilities to participate in everyday activities.
- Trial name
- NCT05017363
- Testing
- ENGAGE
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- University of Alberta
Breast Cancer
Elevate! : An Elderly Breast Cancer Cohort Study
This study is focused on understanding how the investigators can improve upon breast cancer and health outcomes for older participants with breast cancer.
- Trial name
- NCT03818087
- Testing
- Observational cohort
- Where
- 4 sites in United States
- Volunteers
- 253 people
- Sponsor
- Dana-Farber Cancer Institute
Depressive Disorder, Major Depressive Disorder
A Randomized Neuroimaging Trial of Psilocybin in Depression
The goal of this neuroimaging clinical trial is to test whether psilocybin produces significant immediate changes in functional brain activity in networks associated with mood regulation and depression compared to placebo in…
- Trial name
- EMBRACE (NCT06072898)
- Testing
- Psilocybin, Microcrystalline cellulose, Supportive psychotherapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Sunnybrook Health Sciences Centre
Refractory Cancer, Recurrent Cancer
IMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors
The goal of this clinical trial is to evaluate the safety, tolerability and anti-tumor activity of IMA402 in patients with recurrent and/or refractory solid tumors.
- Conditions
- Refractory Cancer, Recurrent Cancer, Solid Tumor, Adult, Cancer
- Trial name
- NCT05958121
- Testing
- IMA402, IMA402 and checkpoint inhibitor, IMA402 and chemotherapy
- Where
- 29 sites in Germany, Netherlands
- Volunteers
- 400 people
- Sponsor
- Immatics Biotechnologies GmbH
Smoking, Problem Drinking
A Medical Assistant-Based Program to Promote Healthy Behaviors in Primary Care
The purpose of the study is to determine whether a program of screening and intervention for four health risk behaviors (smoking, problem drinking, sedentary lifestyle, unhealthy diet) carried out by medical assistants in primary…
- Conditions
- Smoking, Problem Drinking, Sedentary Lifestyle, Unhealthy Diet
- Trial name
- NCT00273806
- Testing
- Intervention for 4 behavioral risks by medical assistants.
- Where
- 6 sites in United States
- Volunteers
- 864 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Cervical Cancer Screening, Human Papilloma Virus
Developing and Implementing HPV SCREENED
This study will assess the feasibility of implementing HPV self-sampling as a primary cervical cancer screening strategy for under-screened women in the emergency department (ED).
- Trial name
- NCT07657104
- Testing
- HPV Self-collection in the ED
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey