Clinical trials: Energy Regulation
Cardiovascular Diseases, Natriuretic Peptides
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes…
- Conditions
- Cardiovascular Diseases, Natriuretic Peptides, Cardiometabolic Diseases, Energy Expenditure
- Trial name
- NCT05216042
- Testing
- Study diet, Exercise capacity VO2 max determination, Exercise Challenge
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Type 2 Diabetes, Obesity
Obesity and Diabetes Prevention Through Science Enrichment
Type 2 diabetes and obesity in children continue to increase at alarming rates with devastating results. However, both these metabolic diseases are largely preventable through adoption of a healthy lifestyle, an understanding of…
- Trial name
- DKENERGY (NCT00541879)
- Testing
- Program ENERGY, comparison
- Where
- United States
- Volunteers
- 2,909 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Healthy
Short-term Regulation of Energy and Macronutrient Balance: Impact of Energy Flux
Aim of the study is to investigate the impact of energy flux (achieved by changes in physical activity) under the conditions of energy balance, caloric restriction and overfeeding in healthy subjects.
- Trial name
- EF (NCT03361566)
- Testing
- physical activity, energy intake
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Energy Balance, Physiology - Regulation of Appetite and Food Intake
The Role of Estradiol and Progesterone on Appetite Regulation and Energy Balance
The goal of this study is to determine if estradiol and progesterone are involved in appetite regulation and energy balance. The study aims to complete a 13 day randomized controlled trial (RCT) where oral supplementation of…
- Trial name
- E2 & P4 in EB (NCT07620587)
- Testing
- Estradiol Only, Progesterone Only, Estradiol and Progesterone Combination
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Appetitive Behavior
Effect of Oral Lactate Ingestion on Appetite Regulation
The goal if this study is to determine how oral lactate ingestion affects markers of appetite regulation. Researchers will compare oral lactate ingestion to a sodium chloride placebo.
- Trial name
- NCT06379815
- Testing
- Sodium Lactate, Sodium Chloride
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Narcolepsy
Body Weight Regulation in Patients With Narcolepsy
This study will measure energy expenditure (the rate at which the body burns calories), physical activity and caloric intake in people with narcolepsy to learn more about how the risk of becoming overweight or diabetic may be…
- Trial name
- NCT00283894
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Appetite Regulation, Energy Intake
Impact of Sourdough Bread Consumption on Long-term Energy Intake: A Pilot Study of Feasibility
The present study is a pilot study examining whether long-term sourdough bread consumption reduces energy intake and blood lipids levels over a period of 4 weeks in free-living normalweight and overweight participants.
- Conditions
- Appetite Regulation, Energy Intake, Body Weight Changes, Eating Behavior
- Trial name
- SOBER (NCT05590611)
- Testing
- Dietary Intervention with Brown Bread, Dietary Intervention with Sourdough Bread
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Obesity, Diet
Effect of Carbonated Soft Drinks on Appetite-Regulation
Compared to solid foods, the nutritional energy of drinks may bypass the appetite regulation leading to obesity development. Although drinks sweetened with aspartame are available the anticipated positive effect of these drinks…
- Trial name
- NCT00776971
- Testing
- Sugar-sweetened soft drink, Aspartame-sweetened soft drink, Semi-skimmed milk
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Children, Exogenous Obesity
The Feeding Dynamic Intervention: Self Regulation of Intake in Preschoolers
In this study the investigators will examine the Feeding Dynamic Intervention (FDI) as a tool to prevent obesity in young children.
- Conditions
- Children, Exogenous Obesity, Eating Behavior
- Trial name
- FeeDIn (NCT01515254)
- Testing
- lifestyle counseling, parental feeding
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Pulmonary Disease, Chronic Obstructive
Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)
More patients with chronic obstructive pulmonary disease (COPD) die from cardiovascular disease than direct pulmonary complications.
- Trial name
- NCT01398943
- Testing
- Tetrahydrobiopterin (BH4), Antioxidant Cocktail
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Augusta University
Healthy, Diabetes Mellitus Type 1
The Effect of Light Therapy on Cellular Energy and Oxidative Stress in Healthy Adults and Type 1 Diabetic Patients
The goal of this clinical trial is to evaluate the effects of low-level light therapy on cellular energy and oxidative stress in healthy adults and patients with Type 1 diabetes.
- Trial name
- PBM-T1D (NCT07833865)
- Testing
- Red and Near-Infrared Light Therapy Pad
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thi-Qar
Overweight and Obesity
Dairy Foods and Weight Loss
Obesity is a national epidemic with multiple causes and complex solutions. Research in both animals and humans has suggested that the inclusion of dairy foods into a moderate calorie restricted diet can increase weight loss and…
- Trial name
- NCT00858312
- Testing
- high dairy diet, Low Dairy
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Obesity, Appetitive Behavior
Regulation of Energy Balance and Metabolism - Mechanisms Behind and Beyond Obesity and Weight Loss
The study aims to investigate homeostatic and hedonic mechanisms regulating appetite, energy balance and metabolism in obesity and the effects of three distinct obesity treatments on these regulatory mechanisms.
- Trial name
- BALANCE (NCT03550339)
- Testing
- SURG, DIET, HAES
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Energy Balance, Energy Expenditure
Effect of Resistance Exercise on Energy Balance and Appetite Regulation in Males and Females
There is growing evidence that males and females may exhibit different acute responses and long-term adaptations to exercise training.
- Conditions
- Energy Balance, Energy Expenditure, Males and Females, Resistance Exercise
- Trial name
- NCT07444021
- Testing
- resistance exercise (males), resistance exercise (females)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Overweight and Obesity
Effects of Oral vs Intravenous Glucose Administration on Novel Candidates of Energy Regulation
Energy regulation in humans is controlled through complicated mechanisms involving among others hormones secreted from different tissues, such as gut, muscle and adipose tissue.
- Trial name
- NCT04888325
- Testing
- Oral glucose, Intravenous glucose
- Where
- Greece
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Metabolic Flexibility
Human Metabolic Flexibility: Its Role in Energy Regulation and Obesity
Obesity is commonly described as a consequence of excess calorie intake. Conventionally, the physiological variables that have been of extensive interest are food intake and energy expenditure.
- Trial name
- NCT04773132
- Testing
- Low Protein
- Where
- Singapore
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Appetite Self-regulation, Pediatric Obesity
Food Form & Energy Intake
This study primarily aims to examine how food presented in various forms (i.e., solid, semi-solid, and liquid) affects children's ability to self-regulate energy intake at a subsequent meal.
- Trial name
- NCT05258097
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity, Underweight
Experimental Approach to Test Predictions of Body Weight Regulation Models
The regulation of human body weight and fatness is not fully understood. Although some models of regulation have been proposed (set point, dual-intervention point, others), no studies have been designed to test their predictions.
- Trial name
- DIP (NCT06309576)
- Testing
- Fasting-refeeding cycle
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Anorexia of Ageing
Impaired Regulation of Energy Balance in Elderly People (Balance Study)
Over the past century life expectancy has risen rapidly. As a result, the proportion of elderly people continues to grow. Elderly people probably have an impaired regulation of energy balance (energy intake versus energy…
- Trial name
- Balance (NCT00561145)
- Testing
- Energy restriction period
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Obesity
Promoting The Self-Regulation Of Energy Intake
The goal of this study is to develop and test the efficacy of a scientifically-based, culturally competent seven-session parent directed, obesity prevention program focused on parental feeding strategies that support young…
- Trial name
- SEEDs (NCT01513343)
- Testing
- Parent and child groups focused on self-regulation of eating
- Where
- 2 sites in United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine