Clinical trials: Energy Metabolism
Obesity
Effect of Dihydrocapsiate on Energy Expenditure in Women
The objective of this study is to test the effect of dihydrocapsiate on energy expenditure in women.
- Trial name
- NCT01773356
- Testing
- Dihydrocapsiate
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ellen Evans
Resting Energy Expenditure, Peritoneal Dialysis
Novel Equation for Estimating Resting Energy Expenditure in Dialysis Patients
The energy and nutrition states are closely associated with dialysis patients' complications and outcomes. To reach the energy balance target, we need the accurate resting energy expenditure level of patients.
- Conditions
- Resting Energy Expenditure, Peritoneal Dialysis, Equation
- Trial name
- NCT04947839
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Obesity and Overweight, Leptin Resistance
Reprogramming Energy Homeostasis in Overweight Individuals Via Exercise, Cognitive, and Social Training
The RESILIENT project is a clinical trial investigating leptin sensitivity in both children and adults with overweight or obesity.
- Conditions
- Obesity and Overweight, Leptin Resistance, Childhood Obesity
- Trial name
- Resilient (NCT06931730)
- Testing
- Nutritional Intervention, Physical Activity training, Cognitive training
- Where
- 2 sites in Italy
- Volunteers
- 240 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Brown Adipose Tissue
Effect of Glyceroltrinitrate on Human Energy Expenditure and Brown Adipose Tissue Thermogenesis
The aim of this study is to evaluate the efficacy of glyceroltrinitrate (Nitroderm® TTS) to activate and expand human BAT as compared to mild cold exposure.
- Trial name
- NEXT (NCT05711199)
- Testing
- Glyceroltrinitrat
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity, PreDiabetes
ADI-PEG20, Obesity and Prediabetes
Th purpose of this study is to determine whether ADI-PEG20 (PEGylated arginine deiminase), an arginine catabolizing enzyme preparation, improves insulin sensitivity, mitochondrial respiration, and energy utilization in…
- Trial name
- NCT05829239
- Testing
- ADI-PEG20
- Where
- United States
- Sponsor
- Washington University School of Medicine
Obesity
The Effects of Mastication on Energy Release From Walnuts
With an emphasis on oral processing, this study seeks to characterize the mechanisms that account for the high satiation properties of walnuts and low energy yield during digestion.
- Trial name
- NCT02927028
- Testing
- Chewing
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Purdue University
Depression
Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram
This study will evaluate changes in brain energy metabolism due to treatment with escitalopram in people with major depressive disorder.
- Trial name
- NCT00183677
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy
Study of the Effects of Temperature on Metabolism in Human Muscle
This study will examine the role of temperature in changing energy metabolism in human muscle. In order to do this, researchers will use magnetic resonance imaging (MRI) to provide information about how parts of muscle operate…
- Trial name
- NCT00001753
- Testing
- Magnetic resonance imaging
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Normal Physiology
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
Background: Diet-induced thermogenesis (DIT) is the amount of energy one's body uses to eat food, absorb the nutrients from the food, and process those nutrients.
- Conditions
- Obesity, Normal Physiology, Healthy Volunteers
- Trial name
- NCT05545306
- Testing
- +200% of dietary requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, fasting, -50% of energy balance requirements. 50% of calories from carbohydrates, 20% from protein, and 30% from fat
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Sleep, Sleep Deprivation
Sleep Loss and Energy Metabolism in People With Family History of Type 2 Diabetes.
The use of energy from food changes when people sleep. However, it is still not known if differences in the amount of nighttime sleep have an effect on the amount of energy that people who have a relative with type 2 diabetes…
- Conditions
- Sleep, Sleep Deprivation, Insulin Resistance, Type 2 Diabetes
- Trial name
- NCT00724087
- Testing
- 5.5-hour bedtime, 8.5-hour bedtime
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Energy Metabolism, Heart Rate
Effects of a Thermogenic Dietary Supplement on Metabolic, Hemodynamic, and Mood Responses
This a randomized, double blind, placebo controlled, crossover design study which measures the effect of an available thermogenic dietary supplement on resting energy expenditure (REE), blood pressure and heart rate, and mood…
- Conditions
- Energy Metabolism, Heart Rate, Blood Pressure, Mood
- Trial name
- NCT03678116
- Testing
- Caffeine (plus Teacrine and Cayenne), Caffeine (plus Teacrine)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Hypothyroidism
Hypothyroidism, Metabolism and Food Intake
This project has the following primary aims: To measure changes in appetite and food intake in newly diagnosed hypothyroid patients during the first six months after starting levothyroxine (L-T4) substitution therapy Secondary…
- Trial name
- Hypomafia (NCT02993562)
- Testing
- Levothyroxine
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Herlev Hospital
Pediatric Obesity
Neural Mechanisms Underlying Children's Responses to Food Portion Size and Energy Density
Increased portion sizes of foods high in energy density (calories per gram of food) have been implicated in the obesity epidemic.
- Trial name
- NCT02759523
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity, Overweight
RCT to Describe the Effects of Colon Delivered Acetate, Propionate and Butyrate on Satiety and Glucose Homeostasis
Obesity, with its associated co-morbidities, is a major public health challenge. It is estimated that by 2050, 60% of men and 50% of women will be clinically obese.
- Trial name
- PRO-ESTER (NCT02451189)
- Testing
- Inulin acetate ester, Inulin propionate ester, Inulin butyrate ester
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Scottish Universities Environmental Research Centre
Iron, Cerebral Blood Flow
16 Weeks' Dietary Supplementation With Iron and Iron + Vitamin C on Cerebral Blood Flow and Energy Expenditure in Women of Reproductive Age
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Conditions
- Iron, Cerebral Blood Flow, Energy Metabolism, Cognitive Function
- Trial name
- NCT04477018
- Testing
- Iron bis-glycinate chelate and vitamin C, Iron bis-glycinate chelate
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Sleep Apnea Syndromes
Effects of CPAP on Diet, Physical Activity, and Cardiovascular Risk
Obstructive sleep apnea (OSA) is characterized by recurrent episodes of partial or complete loss of airflow during sleep, due to narrowing or closure of the upper airway.
- Trial name
- NCT01944020
- Testing
- CPAP
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Columbia University
Type 2 Diabetes, Obesity
Diabetes Virtual Trek: Obesity and Diabetes Prevention Through Science Enrichment
The purpose of this study was to evaluate the effectiveness of a school-to-home education program for it's ability to increase knowledge about, and ability to prevent type two diabetes in children and parents.
- Trial name
- DvtENERGY (NCT00542113)
- Testing
- DvtProgram ENERGY, DvtProgramENERGY
- Where
- 2 sites in United States
- Volunteers
- 1,703 people, healthy volunteers welcome
- Sponsor
- Colorado State University
PreDiabetes, Obesity, Morbid
Metabolic Effects of a Low Carbohydrate Versus a Standard Diet in Morbidly Obese With Prediabetes
To investigate the metabolic effects of a low carbohydrate versus energy-matched standard diet in morbidly obese individuals with prediabetes awaiting bariatric surgery.
- Conditions
- PreDiabetes, Obesity, Morbid, Bariatric Surgery Candidate
- Trial name
- CaPrO (NCT03880162)
- Testing
- Low carbohydrate diet, Energy-matched standard diet
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gut Microbiota Diversity and Composition, Gut Microbiota Modulation
Effects of Barley and Kefir on Gut Microbiota in Physically Active Adults
The purpose of this randomized controlled clinical trial is to investigate whether a four-week dietary intervention consisting of a daily meal with barley and kefir can influence gut microbiota diversity and composition in…
- Conditions
- Gut Microbiota Diversity and Composition, Gut Microbiota Modulation, Probiotic, Prebiotic
- Trial name
- GUTS (NCT07864779)
- Testing
- Barley, Kefir
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western Norway University of Applied Sciences
Healthy
Energy Expenditure in Golf
Structured exercise and physical activity are well known to not only improve physical fitness, but also alter various health parameters in a positive fashion.
- Trial name
- NCT04496323
- Testing
- EE Golf
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
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