Clinical trials: Energy Metabolism
Obesity
Effects of Consuming Protein Shakes, Varying in Protein Source, on Appetite, Satiety and Energy Intake
Background: Consistent data from acute, single preload studies demonstrate improvements in perceived appetite and satiety following the consumption of high-protein preloads compared to normal protein preloads.
- Trial name
- NCT03132376
- Testing
- Water Preload Drink, Whey Protein Isolate Drink, Micellar Casein Protein Drink
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Purdue University
Metabolic Health, Gut Hormones
Breaking Sitting and Metabolic Health in Sedentary Lean Adults
The purpose of this project is to investigate the effects of breaking up prolonged sitting on postprandial metabolic responses, gut hormones secretion and energy balance in sedentary lean adults.
- Conditions
- Metabolic Health, Gut Hormones, Energy Balance
- Trial name
- NCT05306613
- Testing
- Prolonged sitting, Breaking sitting
- Where
- Taiwan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Resting Metabolic Rate
Energy Cost for Holding a MedGem® Indirect Calorimeter
The goal of this clinical protocol is to perform a randomized crossover study to determine the energy cost of holding the MedGem® device above a person's normal resting metabolic rate (RMR) compared to not holding the MedGem®…
- Trial name
- MEDGEM (NCT03035903)
- Testing
- Not holding, then holding the MedGem®, Holding, then not holding the MedGem®
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Lipid Overnutrition, Constitutional Thinness
Adaptation of Lipid and Energy Metabolism During a Lipid Overnutrition in Constitutional Thinness
For a given food intake, fat and energy metabolism in adipose tissue and muscle adapt to nutrient intakes. This adaptation to nutrition may be impaired in susceptible individuals or in obese patients by promoting weight gain…
- Trial name
- Surnutrition (NCT01224561)
- Testing
- Lipid overnutrition
- Where
- 3 sites in France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cold Exposure
The Effect of Cold Exposure on Energy Expenditure
Cold-induced thermogenesis, or the increase in energy expenditure upon cold exposure, indicates metabolic stress, as such, cold-induced thermogenesis may signal an appropriate stimulus to improve metabolic health.
- Trial name
- NCT05107570
- Testing
- Cold exposure
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Obesity
Probiotic for Weight Management in Overweight and Obese Adults
To evaluate the impact of pasteurized Akkermansia muciniphila Akk11 capsules versus placebo on body composition (including body weight, BMI, body fat percentage, waist-to-hip ratio, wrist circumference, visceral fat area, and…
- Trial name
- NCT07507929
- Testing
- Probiotic
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Obesity
Functional Lipids and Appetite Regulation
To evaluate the short-term effects of structured lipids on appetite regulation.
- Trial name
- NCT00259259
- Testing
- SALATRIM
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Narcolepsy
Body Weight Regulation in Patients With Narcolepsy
This study will measure energy expenditure (the rate at which the body burns calories), physical activity and caloric intake in people with narcolepsy to learn more about how the risk of becoming overweight or diabetic may be…
- Trial name
- NCT00283894
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Body Weight
Beverage Consumption and Fine Motor Control
The aim of this study will be to compare the effects of daily consumption of aspartame, rebaudioside a, saccharin, sucralose, and sucrose on body weight and composition in a standardized protocol.
- Trial name
- LCS (NCT02928653)
- Testing
- Beverage
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Purdue University
Energy Metabolism
Maximal Fat Oxidation During Exercise
It is well known that, even in quite homogenous populations, inter-individual variability in fat oxidation during exercise, in particular MFO, is quite large.
- Trial name
- FatMaxx (NCT04935983)
- Testing
- High CHO, Low CHO
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Heart Septal Defects, Ventricular
Study of Energy Expenditure in Infants With Ventricular Septal Defects
OBJECTIVES: I. Compare the total daily energy expenditure in infants with ventricular septal defects vs healthy control infants.
- Trial name
- NCT00006272
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Mobility Limitation
HealthySteps: Exercise for Older Adults With Mobility Limitation
This study will compare three different exercise programs in older adults who report difficulty walking and will determine if the programs improve walking.
- Trial name
- HealthySteps (NCT01740505)
- Testing
- Timing and Coordination, Aerobic Walking, Stretching and Relaxation
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Reinforcing Value of Food
Food Reinforcement, Weight Status, and Energy Density
The investigators previous studies have shown that obese and non-obese individuals respond differently to daily intake of snack food.
- Trial name
- NCT03981172
- Testing
- Daily snack food intake
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Obesity
Weight Loss Composition and Metabolic Adaptation During Hypocaloric Dieting
Weight loss induced by hypocaloric dietary interventions is commonly accompanied by reductions in resting metabolic rate (RMR), a phenomenon often described as metabolic adaptation.
- Trial name
- NCT07627256
- Testing
- Hypocaloric Diet
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Depression
Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram
This study will evaluate changes in brain energy metabolism due to treatment with escitalopram in people with major depressive disorder.
- Trial name
- NCT00183677
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Food Selection, Obesity
Changing Portion Size Descriptions in a Cafeteria
The goal of this this intervention is to test the degree to which a portion size labeling intervention influences consumer selection of smaller portions at two large cafés.
- Conditions
- Food Selection, Obesity, Weight Gain, Food Preferences
- Trial name
- NCT06263621
- Testing
- Intervention "Standard"
- Where
- 2 sites in United States
- Volunteers
- 101,481 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sports Physical Therapy
WB-EMS Increase Energy Expenditure at Rest and During Uphill Walking Exercise
Whole-body electrical stimulation (WB-EMS) has become increasingly popular as a tool to provide additional benefits compared to conventional exercise.
- Trial name
- NCT05218512
- Testing
- WB-EMS
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Poor Energy Levels, Poor Metabolism
A Clinical Trial to Evaluate the Effects of a Supplement on Supporting Signs of a Healthy Metabolism
This study evaluates the effects of Love Wellness Energize, a dietary supplement, on supporting signs of a healthy metabolism in women aged 25-45 who report poor energy levels, perception of poor metabolism, difficulty with…
- Conditions
- Poor Energy Levels, Poor Metabolism, Difficulty With Weight Management, Bloating
- Trial name
- NCT07765407
- Testing
- Love Wellness Energize
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Energy Intake, Energy Metabolism
Mass Balance of Orally Administered [14C] (3S,4S,5R)-1,3,4,5,6-pentahydroxy-hexan-2-one
Worldwide almost 40% of the adult population is overweight (including >10% obese), and more than 350 million children (up to the age of 19) are overweight.
- Trial name
- TrueCal (NCT06230900)
- Testing
- (3S,4S,5R)-1,3,4,5,6-pentahydroxy-hexan-2-one, 14C-(3S,4S,5R)-1,3,4,5,6-pentahydroxy-hexan-2-one
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Obesity; Drug
The Effect of Weekly Semaglutide Treatment on Energy Expenditure
This study will test the effects of weekly injections of the glucagon like peptide-1 (GLP-1) agonist semaglutide on energy expenditure and metabolic parameters in a 24 week double-blind, placebo-controlled dose escalation…
- Trial name
- NCT06390501
- Testing
- Semaglutide
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences