Clinical trials: Endothelial Cell Density
Metabolic Syndrome X
Effect of Exercise Training on the Function of the High Density Lipoprotein (HDL)-Cholesterol, Endothelial Function and Endothelial Progenitor Cells in Patients With Metabolic Syndrome(HERMET-Study)
The purpose of the present study is to characterize the quality of HDL-Cholesterol in patients with metabolic syndrome and reduced blood HDL-Cholesterol levels and to examine the effect of exercise training on the…
- Trial name
- HERMET (NCT00515476)
- Testing
- physical exercise
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Amount of Corneal Flattening (Kmax Flattening), Change in the Endothelial Cell Count
Topo-Pachymetric Customized Accelerated Epi-On Vs Accelerated Epi-Off Corneal Cross Linking in Keratoconus Management
The objective of this study is to compare the clinical effectiveness and safety of Topo-Pachymetric Customized Accelerated Epithelium-On (aCFXL) to Standard Accelerated Epithelium-Off (aCXL) Corneal Collagen Cross-Linking in the…
- Trial name
- NCT06549387
- Testing
- Corneal cross linking
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Glaucoma, Endothelial Cell Loss, Corneal
Changes in Corneal Endothelial Cell Density After Transscleral ab Interno Glaucoma Gel Stent Implantation
The objective of this study is to evaluate the change of endothelial cell count after XEN45 in patients with or without cataract operation.
- Trial name
- NCT04547036
- Testing
- XEN45
- Where
- Austria
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Healthy
Corneal Endothelial Cell Density Changes In Healthy Subjects, When Administered ISV-403 for 5 Days
The objective of this study is to evaluate the effect on corneal endothelial cell density changes when ISV-403 is administered for five (5) days compared to no drug treatment, in healthy subjects.
- Trial name
- NCT01120418
- Testing
- Besifloxacin Ophthalmic Suspension 0.6%
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Metabolic Syndrome
The High Density Lipoprotein and Endothelial Function, Niacin and Nitric Oxide Study (The High-Ennd Study)
The aim of the present study is to characterize novel mechanisms whereby HDL may exert potent vasculoprotective effects independent of reverse cholesterol transport, in particular the effect of HDL on the regulation of the…
- Trial name
- NCT00346970
- Testing
- Extended-Release Niacin
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Corneal Endothelial Cell Changes
Corneal Endothelial Cell Density Changes, When Mapracorat Ophthalmic Suspension 3%, is Administered for 14 Days
The objective of this study is to evaluate the effect on corneal endothelial cell density (cells/mm²) changes at 3 months when mapracorat ophthalmic suspension, 3% is administered QID (four times daily), for 14 days in healthy…
- Trial name
- NCT01736462
- Testing
- Mapracorat
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Uveitis, Posterior
Corneal Endothelial Cell Density in Eyes Treated With a Fluocinolone Acetonide Intravitreal Implant
An Observational Change-From-Baseline Evaluation of Corneal Endothelial Cell Density in Eyes Treated with a Fluocinolone Acetonide Intravitreal Implant
- Trial name
- NCT03145025
- Testing
- Retisert, Fluocinolone Acetonide Intravitreal Implant
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Corneal Endothelial Cell Loss, Ozone Therapy
Effect of Systemic Ozone Therapy on Corneal Endothelium
This study evaluates the safety of systemic ozone therapy on the corneal endothelium, a vital non-renewable tissue that maintains corneal transparency.
- Trial name
- OZON-CORNEA (NCT07718100)
- Testing
- Systemic Ozone Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Endophthalmitis
Evaluation of Efficacy and Safety of Intracameral Moxifloxacin for Prevention of Postcataract Endophthalmitis.
There has thus far been only one randomized and masked clinical trial in the world to evaluate the efficacy of the intraoperative intracameral injection of antibiotics with the objective of preventing endophthalmitis following…
- Trial name
- NCT02770729
- Testing
- Moxifloxacin, No injection of moxifloxacin
- Where
- Brazil
- Volunteers
- 3,640 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Pseudoexfoliation Syndrome
The Endothelial Count in Pxf
Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.
- Trial name
- NCT03265457
- Testing
- Specular microscopy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pterygium
Pterygium Head Body MMC1: Two Different Surgical Procedures and Their Effect on Endothelial Cell Count.
To evaluate changes in endothelial cell count after pterygium surgery with mitomycin C (MMC) 0.02%
- Trial name
- PHB-MMC1 (NCT02641132)
- Testing
- Mitomycin C 0.02%, Pterygium surgery
- Where
- 2 sites in Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Retinal Diseases
Measuring Corneal Cells With Specular Microscopy
Assess changes in the corneal cell count using Specular Microscopy following tretments with Anti-VEGF injections
- Trial name
- NCT01792154
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Retina Institute of Hawaii
Corneal and Endothelial Cell Measurements
Comparative Study of the TOMEY Specular Microscope EM-4000 and the Konan CellChek XL
The Tomey EM-4000 Specular Microscope is designed to observe and analyze corneal endothelium.
- Trial name
- NCT02977793
- Testing
- Tomey EM-4000 Specular Microscope, Konan CellChek XL Specular Microscope
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Tomey Corporation
Endothelial Cell Density Loss
Study of Endothelial Cell Condition After Cataract Surgery Performed Using Capsulorhexis or ZEPTO
This study will use images of the subjects' corneal endothelium obtained using non-invasive specular microscopy to obtain corneal endothelial cell density, the coefficient of variation in endothelial cell size, and the percentage…
- Trial name
- ZEPTO (NCT04882189)
- Testing
- Imaging
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centricity Vision, Inc.
Pseudoexfoliation
Corneal Endothelium Evaluation After Phacoemulsification in Diabetec and Non-diabetic Patients With Pseudoexfoliation
Our study is a comparative study, that was conducted to evaluate the corneal endothelial cells changes and central corneal thickness after uncomplicated phacoemulsification and intra ocular lens (IOL) implantation in normal…
- Trial name
- NCT04965168
- Testing
- phacoemulsification of the lens
- Where
- Egypt
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Minia University
Silicon Oil Effect on Cornea, Corneal Biomechanics
Silicone Effect on Corneal Endothelium and Corneal Biomechanics Using Corvis ST
Brief Summary The goal of this observational study is to investigate the effects of silicone oil tamponade on corneal endothelial cell density (ECD), morphology, and biomechanics in patients undergoing vitrectomy for retinal…
- Trial name
- NCT06861946
- Testing
- Corvis ST, Conrneal endothelial cell density
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Effect of Cataract Surgery on Corneal Endothelium; About 2 Techniques
Qualitative and Quantitative Endothelium Changes After Cataract Surgery: Ultrasound Phacoemulsification vs Nanolaser Technique
Purpose: The aim of this study was to evaluate corneal endothelial cell density and morphology, central corneal thickness, and best visual acuity using US phacoemulsification or Nanosecond laser technique.
- Trial name
- NCT05886283
- Testing
- phacoemulsification, utrasound phacoemulsification, nanolaser phacoemulsification
- Where
- Tunisia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Corneal and Endothelial Cell Measurements
Comparative Study of Specular Microscope for Cell Density, Coefficient of Variation, Hexagonality and Corneal Thickness
The primary objective of this clinical study is to collect clinical data to support an FDA 510(k) submission for the Nidek Specular Microscope CEM-530.
- Trial name
- NCT01729975
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.