Clinical trials: Endoscopy
Colon Cancer, Surgery
Evaluation the Safety of Indocyanine Green Guided Treatment of Henle Trunk
Laparoscopic right hemicolectomy D3 dissection or complete mesocolic excision (CME) has become the standard treatment for right hemi-colon cancer, and the treatment of Henle trunk is one of the difficulties of the operation.
- Trial name
- SIGHELC (NCT05125393)
- Testing
- Laparoscopic linear stapler
- Volunteers
- 128 people
- Sponsor
- Shanghai East Hospital
Low-output External Gastrointestinal Fistula
Glue Sealing for Patients With Low-Output ECFs
Adjuvant use of fibrin glue (FG) in the fistula tract has been shown to promote closure of low-output ECFs. The primary objectives of this study are to compare the clinical efficacy, safety of autologous platelet-rich fibrin glue…
- Trial name
- Glue-sealing (NCT01672593)
- Testing
- Endoscopy exploration and glue application, Anti-Bacterial Agents, Nutrition support
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jinling Hospital, China
Sinusitis
Manuka Honey Irrigation After Sinus Surgery
All adult (over 19 years) patients undergoing sinus surgery for chronic rhinosinusitis (CRS) or allergic fungal sinusitis (AFS) that do not meet the exclusion criteria will be included in the study.
- Trial name
- NCT01350193
- Testing
- Manuka Honey, Saline Irrigation
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- St. Paul's Hospital, Canada
Neoplasms, Biliary Stricture
The Diagnostic Value of Combinatory EUS and ERCP in Unclear Lesions
ERCP with brush cytology has a poor to moderate accuracy in unclear biliary lesions. Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) for cytology may override some of these shortcomings.
- Conditions
- Neoplasms, Biliary Stricture, Biliary Tract Neoplasms, Biliary Tract Diseases
- Trial name
- NCT03504293
- Testing
- Combinatory EUS and ERCP
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Sahlgrenska University Hospital
Malignant Colorectal Polyp, Colorectal Cancer
A Prospective Registry of Patients With Endoscopically Resected Malignant Colorectal Polyps (pT1 Colorectal Cancer)
The purpose of this study is to learn more about malignant colorectal polyps (early colorectal cancers removed during colonoscopy) and the risk that cancer remains, comes back, or spreads after the polyp is removed.
- Conditions
- Malignant Colorectal Polyp, Colorectal Cancer, T1 Colorectal Cancer
- Trial name
- NCT07619079
- Testing
- Questionnaires
- Where
- 7 sites in United States
- Volunteers
- 500 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Esophageal Motility Disorders
Monopolar and Bipolar Current RFA Knife in POEM
Per Oral Endoscopic Myotomy (POEM) is performed for various esophageal muscular disorders, including achalasia and other spastic esophageal conditions.
- Trial name
- NCT05272046
- Testing
- Per-oral Endoscopic Myotomy, Speedboat (Bipolar electrocautery knife)
- Where
- 3 sites in United States, India and 1 more
- Volunteers
- 104 people
- Sponsor
- Baylor College of Medicine
Sinusitis
Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery
Sinusitis is a common medical problem, which significantly decreases patients' quality of life (QOL). Patients may have symptoms such as headaches, sinus pressure, nasal congestion and drainage, decreased sense of smell, and…
- Trial name
- NCT02900794
- Testing
- Gold Laser, Microdebridement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Siewert Type II Adenocarcinoma of Esophagogastric Junction
Comparison of Different Operations for Siewert Type II Adenocarcinoma of Esophagogastric Junction
The incidence of esophagogastric junction has been increasing in recent years, and surgery is an important method for the treatment of adenoma at the esophagogastric junction.
- Trial name
- NCT05356520
- Testing
- Endoscopy Ivor-lewis, Laparoscopic transabdominal enlarged gastrectomy
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Chronic Pancreatitis
The PASTEC Study: Endoscopic Stenting Versus Surgery for the Treatment of Bile Duct Stricture in Chronic Pancreatitis
Biliary obstruction complicates the course of chronic pancreatitis in 3%-23% of patients and in these cases, endoscopy and surgery are the treatment modalities of choice.
- Trial name
- PASTEC (NCT02366988)
- Testing
- Endoscopic Biliary Stenting, Surgical treatment Bilio-enteric anastomosis
- Where
- 7 sites in France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Lille
Colorectal Neoplasms, Colonic Polyps
Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study
This prospective randomized controlled study aims to evaluate the diagnostic accuracy of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for detection and optical characterization of…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma, Serrated Polyps
- Trial name
- INSIGHT (NCT07797361)
- Testing
- White Light Endoscopy, Versatile Intelligent Staining Technology, Spectral Flexible Imaging
- Where
- Brazil
- Volunteers
- 990 people
- Sponsor
- Alexandre Vontobel Padoin
Anastomosis; Complications, Colon Disease
Computed Tomography vs. Endoscopy Study
Patients undergoing elective surgery for left-sided colon resection are asked to participate in this study: Every patient undergoes two types of examinations (endoscopy, CT scan) on day 3, 4 or 5 postoperatively.
- Conditions
- Anastomosis; Complications, Colon Disease, Leak, Anastomotic
- Trial name
- NCT03148054
- Testing
- Computer Tomography and Endoscopy
- Where
- Switzerland
- Volunteers
- 416 people
- Sponsor
- Spital Limmattal Schlieren
Otolaryngological Disease, Artificial Intelligence
To Develop and Validate a Nasoendoscopic Intelligent Diagnostic System for Nasopharyngeal Carcinoma
Nasopharyngeal carcinoma (NPC) occurs at a high frequency in southern China, northern Africa, and Alaska, with a reported incidence of 30 cases per 100 000 in Guangdong Province.
- Trial name
- NCT04547673
- Testing
- rigid nasal endoscopes
- Where
- 3 sites in China
- Volunteers
- 1,000 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Pancreas Adenocarcinoma
Establishment of Pancreas Cancer and Cancer-associated Fibroblast Using EUS-guided Biopsy Samples
Organoid has emerged as the novel platform for preclinical anticancer drug testing in pancreatic ductal adenocarcinoma (PDA). However, most organoid models are not reconstituted with a tumor microenvironment.
- Trial name
- NCT05571956
- Testing
- Pancreatic ductal adenocarcinoma organoids and cancer-associated fibroblasts establishment group
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Ajou University School of Medicine
Portal Hypertension
Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary Prophylaxis
Background: Both endoscopic variceal ligation (EVL) and propranolol are valuable methods for secondary prophylaxis of variceal bleeding. Addition of ISMN to propranolol improves the efficacy of drug therapy.
- Trial name
- Secondary (NCT00766805)
- Testing
- EVL + Propranolol + Isosorbide 5 mononitrate, EVL alone
- Where
- India
- Volunteers
- 177 people
- Sponsor
- Govind Ballabh Pant Hospital
Gastric Polyps, Intestinal Polyps
Recurrence After Gastric and Intestinal Polyp Resection
This is a retrospective and prospective cohort study designed to evaluate the recurrence rate and identify risk factors after endoscopic resection of gastric and intestinal polyps.
- Conditions
- Gastric Polyps, Intestinal Polyps, Colon Polyps, Colorectal Polyps
- Trial name
- RAGIP (NCT07314554)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- LanZhou University
Crohn's Disease
Endoscopic Relapse Risks Evaluation After Ileocolic Resection for Crohn's Disease
Aim of the study: To evaluate risk factors of endoscopic relapse after ileocolic resection in a cohort of Crohn's disease patients treated with anti-TNF agents.
- Trial name
- RIC-1 (NCT06299631)
- Testing
- Ileocolic resection
- Where
- France
- Volunteers
- 133 people
- Sponsor
- University Hospital, Montpellier
Pancreatic Fistula
Ultrasound Elastography for Prediction of Postoperative Pancreatic Fistula
The purpose of this study is to assess the value of preoperative objective modalities such as endoscopic ultrasound elastography and magnet resonance imaging in predicting development of postoperative pancreatic fistula in…
- Trial name
- PMPPOPF (NCT02589379)
- Testing
- Pancreatic Resection
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- University of Zurich
Gastric Cancer, Proximal Gastric Adenocarcinoma
Surveillance Endoscopy After Proximal Gastriectomy With Double Tract Reconstruction.
The primary purpose of surveillance endoscopy after gastric cancer surgery is to detect malignancy recurrence in the remnant stomach.
- Trial name
- NCT06477562
- Testing
- Endoscopy
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Saint Vincent's Hospital, Korea
Hydrocephalus, Normal Pressure
A Study Comparing Shunt Placement Versus Endoscopic Third Ventriculostomy in the Treatment of Hydrocephalus
The main purpose of this study is to compare two types of treatment of hydrocephalus: placement of a ventriculoperitoneal (VP) shunt versus an endoscopic third ventriculostomy (ETV).
- Trial name
- NCT01115270
- Testing
- Non-invasive measures
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- University of California, Los Angeles
Colorectal Adenoma, Colorectal Polyp
To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard Colonoscopy Without Artificial Intelligence Software Assistance in Participants Between 45 and 75 Years of Age
The aim of this study is to assess the efficacy of Ultivision Artificial Intelligence (AI) Software in detecting adenomas in screening colonoscopy procedures. The safety of Ultivision AI Software will also be assessed.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colorectal Adenocarcinoma, Colorectal SSA
- Trial name
- AIDA (NCT04196088)
- Testing
- Ultivision Artificial Intelligence Software, No Artificial Intelligence Software enhancement
- Where
- 9 sites in United States
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Docbot, Inc.