Clinical trials: Endometrial Sampling
Biopsy Wound, Endometrial Hyperplasia
Effect of Stress Ball Use on Anxiety Level During Endometrial Biopsy Procedure
The aim of this study is to determine the effect of stress ball application on the anxiety level during the endometrial biopsy procedure. This research is planned as a randomised controlled study.
- Conditions
- Biopsy Wound, Endometrial Hyperplasia, Endometrial Neoplasms
- Trial name
- NCT06171581
- Testing
- stress ball, control
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Sterility, Female
Endometrial Local Injury Before First IVF : Evaluation of Pregnancy Rate
In spite of all progress realized in the field of assisted reproduction the pregnancy rate by In vitro fertilization (IVF) in France, across indications, is only 23% after IVF cycle.
- Trial name
- BEONE (NCT02522806)
- Testing
- endometrial biopsy
- Where
- France
- Volunteers
- 315 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Infertility, Recurrent Implantation Failure
Endometrial Biopsy Protocol for In Vitro Fertilization (IVF)
Endometrial biopsy has been shown to improve IVF pregnancy and live birth rates. The optimal time of performing the biopsy is yet to be established.
- Trial name
- NCT01278706
- Testing
- endometrial biopsy/ies
- Where
- 2 sites in Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Office-based Endometrial Sampling Procedures
Effectiveness of Paracervical Block in Endometrial Sampling Procedures for Pain Control
Office-based endometrial procedures are preferred over diagnostic dilation and curettage, nowadays. Paracervical block is single-shot nerve block that involve a one-time injection of local anesthetic adjacent to the utero-vaginal…
- Trial name
- NCT04572828
- Testing
- Paracervical Block, 550 mg Naproxen Sodium 60 minutes before the procedure, The capped needle
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ege University
Pain
Endometrial Biopsy Instrument Comparison Study
The purpose of this study is to determine the level of pain women experience during an endometrial biopsy and the effect that the biopsy tool might have on that pain.
- Trial name
- NCT00613925
- Testing
- Pipelle de Cornier, Explora curette
- Where
- 2 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain
EMLA Cream as Analgesic for Outpatient Gynecological Procedures
The goal of this clinical trial is to compare pain perception in the study participant population undergoing the following gynecological procedures: Intra Uterine Device (IUD) insertion, hysteroscopy, and endometrial biopsy and…
- Trial name
- NCT05970354
- Testing
- EMLA Cream, VersaPro Cream Base for Compounding
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Infertility, Female
Clinical Efficacy of Virtual Reality During Office Hysteroscopy and Endometrial Biopsy in Subfertility
This study is a comparison between the current standard practice of performing a diagnostic hysteroscopy and a relatively recently developed technology that is added to the standard diagnostic hysteroscopy.
- Trial name
- HYSVIR (NCT04438759)
- Testing
- Oncomfort, commercially available Virtual Reality headset
- Where
- Belgium
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Embryo Implantation
Assessment of Endometrial Receptivity in Recipients of Donated Oocytes
The purpose of this study is to determine whether endometrial receptivity markers obtained by endometrial sampling are effective in prediction of in vivo human embryo implantation.
- Trial name
- ERPOD (NCT00506480)
- Testing
- endometrial sampling
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Endometrial Cancer, Lynch Syndrome
Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire
The goal of this study is to find out if self-collected vaginal swabs can be used to detect early signs of uterine cancer or related conditions in people with Lynch syndrome (LS) who still have their uterus.
- Trial name
- Lynch-SCAN (NCT07194551)
- Testing
- Vaginal DNA swab, microbiome swab and pH test
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Abnormal Uterine Bleeding
Comparison of Manual Vacuum Aspiration and Dilatation and Curettage for Endometrial Sampling Adequacy in Women With Abnormal Uterine Bleeding
This randomized controlled trial was conducted in the Department of Obstetrics and Gynecology, Sheikh Zayed Hospital, Rahim Yar Khan, to compare two commonly used methods for obtaining endometrial tissue in women aged 30 to 60…
- Trial name
- NCT07349108
- Testing
- Manual Vacuum Aspiration, Dilatation and Curettage
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Sheikh Zayed Medical College
Infertility
Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women
The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.
- Trial name
- NCT02219425
- Testing
- endometrial biopsy
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Implantation Failure, Infertility
Endometrial Biopsy Prior to IVF in Those Patients With Prior Implantation Failure
This proposed research is a single center, prospective, single-blinded, randomized controlled trial, designed to evaluate IVF pregnancy outcomes following endometrial injury in 254 patients with implantation failure.
- Trial name
- EMBX/IVF (NCT01800513)
- Testing
- Endometrial Biopsy
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Endometrial Cancer, Lynch Syndrome
Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (called the endometrium) to help screen for endometrial cancer.
- Conditions
- Endometrial Cancer, Lynch Syndrome, Screening, Early Detection of Cancer
- Trial name
- SCREEN-CUP (NCT07220239)
- Testing
- Menstrual cup use
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Jessica D. St. Laurent, MD
Endometrium, Biopsy
Tenaculum in Endometrial Sampling Procedure
Most of gynecological office procedure such as endometrial sampling procedure, hysterosalpingography, hysteroscopy, insertion of contraceptive intrauterine device, difficult intrauterine insemination or embryo transfer procedures…
- Trial name
- Tenaculum (NCT01506778)
- Testing
- Tenaculum
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Cukurova University
Women in the Reproductive Age Group, Undergoing Laparoscopy for Pelvic Pain and/or Infertility
Endometrial Biopsy as Diagnostic Method for Endometriosis and Endometrioma
Our aim was to evaluate the efficacy of examining endometrial biopsy specimens for nerve fibers as a diagnostic test for endometriosis and endometrioma in a double-blind comparison with diagnostic laparoscopy.
- Conditions
- Women in the Reproductive Age Group, Undergoing Laparoscopy for Pelvic Pain and/or Infertility, Not Currently Receiving Hormonal Treatment for at Least 3 Months Prior to Laparoscopy.
- Trial name
- NCT01022372
- Testing
- Endometrial biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Infertility
Endometrial Biopsy in Infertile Patients
When a woman becomes pregnant, the fertilized egg attaches itself to the lining of the uterus (endometrium). The endometrium is constantly changing throughout a woman's menstrual cycle in response to the female hormones estrogen…
- Trial name
- NCT00064935
- Testing
- Endometrial biopsy
- Where
- 8 sites in United States
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometrial Diseases
The Effect of Progressive Muscle Relaxation Exercise Applied Before Endometrial Biopsy on Pain, Anxiety Level and Patient Comfort in Premenopausal Women
This study was designed to determine the effect of progressive muscle relaxation exercises performed before endometrial biopsy on pain, anxiety levels, and patient comfort in premenopausal women.
- Trial name
- NCT07694037
- Testing
- progressive muscle relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Pain in Endometrial Biopsy, Abnormal Uterine Bleeding
The Effect of the Valsalva Maneuver in Endometrial Biopsy: A Randomized Controlled Trial
Endometrial sampling with a pipelle is a common procedure used to collect a small sample from the lining of the uterus. During the procedure, the cervix is sometimes held with a surgical instrument called a tenaculum, which may…
- Trial name
- NCT07496905
- Testing
- endometrial biopsy, Tenaculum Application, Valsalva Maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Menorrhagia, Endometrial Neoplasms
Evaluation of the Goldstein SonoBiopsy™ Catheter for Diagnosing Endometrial Pathology
To assess the adequacy of an endometrial biopsy sample obtained using sonohysterography.
- Conditions
- Menorrhagia, Endometrial Neoplasms, Polycystic Ovary Syndrome, Uterine Neoplasms
- Trial name
- NCT01969396
- Testing
- SonoBiopsy Catheter, Endometrial biopsy catheter
- Where
- Panama
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated