Clinical trials: Endocarditis Infective
Infective Endocarditis, Cardiac Sarcoidosis
Evaluation of the Impact of a Patient Education Protocol on the Quality of 18F-FDG PET Imaging Indicated for Investigation of Cardiac Inflammation
The aim of this study is to assess the impact of implementing a patient education and preparation protocol for FDG PET (18F-FDG PET) imaging on the quality of imaging results.
- Trial name
- CARTEP (NCT07029295)
- Testing
- Sending a link to the video, Compliance questionnaire, Determination of beta-hydroxybutyrate (BHB) in capillary blood
- Where
- 2 sites in France
- Volunteers
- 138 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Implantable Electronic Device Infections, Infective Endocarditis
Oritavancin for CIED Infections With MDR Gram-positive Cocci
The study aimed to conduct a randomized, non-inferiority controlled trial to compare the short- and medium-term efficacy and safety of two antibiotic dosage regimens in cardiac implantable electronic devices (CIED) infections…
- Conditions
- Cardiac Implantable Electronic Device Infections, Infective Endocarditis, Multidrug-resistant Bacteria Screening, Gram Positive Bacterial Infection
- Trial name
- ORI-4-CIEDi (NCT07013552)
- Testing
- Administration of a single or repeated dose of a long half-life antibiotic - oritavancin, Administration of a repeated dose of a short half-life antibiotic - vancomycin
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Silesia
Infective Endocarditis
Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study
Introduction. Comprehensive data on infective endocarditis in developing countries are scarce. Objectives: Description of the characteristics (clinical and microbiological) and assessment of the outcomes of infective endocarditis…
- Trial name
- EndoDev (NCT02128139)
- Where
- 6 sites in Fiji, Laos and 3 more
- Volunteers
- 300 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Endocarditis Infective
Prognosis and Management of Infective Endocarditis Using the Clinical Data Warehouse From AP-HP
"Infective endocarditis (IE) is a rare but severe condition with significant morbidity and mortality, with in-hospital mortality reaching 20% and 1-year mortality up to 40%.
- Trial name
- ENDO-EDS (NCT06957119)
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infective Endocarditis
Hemoadsorption for Prevention of Vasodilatory Shock in Cardiac Surgery Patients With Infective Endocarditis
Infective endocarditis (IE) is associated with high hospital mortality for various reasons; one of them is circulatory failure in patients who undergo cardiac surgery for IE.
- Trial name
- REMOVE (NCT03266302)
- Testing
- hemoadsorber for removal of cytokines
- Where
- 14 sites in Germany
- Volunteers
- 288 people
- Sponsor
- Jena University Hospital
Infective Endocarditis
PET/MR Imaging In Patients With Infective Endocarditis
PET scanning (positron emission tomography) is a well-established technique used to identify areas of interest within the body. It involves injecting a radioactive tracer which highlights abnormal areas.
- Trial name
- NCT03626571
- Testing
- 18F-FDG
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Edinburgh
Sepsis, Infective Endocarditis
Study of Leukocyte Immunophenotype and the Lipid Transport System as Predictive Biomarkers of Severe Bacterial Infections
Current study evaluates the relationship between cell immunity and lipid transport systems in patients with severe bacterial infections (on the model of pneumonia, infective endocarditis, sepsis) in order to develop new methods…
- Conditions
- Sepsis, Infective Endocarditis, Pneumonia, Bacterial
- Trial name
- NCT04178915
- Testing
- Bood leukocyte subsets, The cholesterol content of the cell membrane of T-cells and monocytes
- Where
- Belarus
- Volunteers
- 100 people
- Sponsor
- The Republican Research and Practical Center for Epidemiology and Microbiology
Congenital Heart Disease (CHD), Infective Endocarditis (IE)
Electronic Archive of Patients With Congenital Heart Disease and Diagnosis of Infective Endocarditis
The objective of the study is to create an electronic archive in which to census all newly diagnosed or already diagnosed cases of infective endocarditis and congenital heart disease after 01 January 2022 at the IRCCS AOU Bologna…
- Trial name
- IE-CHD (NCT06777615)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Infective Endocarditis, Native Valve Endocarditis
Impact of FDG-PET/CT on Management of Patients with Native Valve Infective Endocarditis
The proposed study is a multicentric prospective observational cohort study of patients with suspected NVE. The study population includes those with Possible IE according to the modified Duke criteria and investigated at one of…
- Trial name
- PET-NAVIE (NCT04792281)
- Where
- 6 sites in Canada
- Volunteers
- 97 people
- Sponsor
- Montreal Heart Institute
Endocarditis Infective
Antibiotics Vs Antibiotics and Surgical ThERapy for Infective Endocarditis
Infective endocarditis (IE) is a deadly disease and the incidence is increasing. An important initial assessment of patients with IE includes whether surgical treatment is indicated; yet, appropriate data to guide this assessment…
- Trial name
- ASTERIx (NCT05061355)
- Testing
- Heart valve surgery
- Where
- 15 sites in Denmark, Germany and 2 more
- Volunteers
- 496 people
- Sponsor
- Emil Loldrup Fosbol
Infective Endocarditis
Early Feasibility Study of Somatostatin Receptors PET Imaging for the Diagnosis of Infective Endocarditis
Study hypothesis: 68Ga-DOTATOC PET/CT could detect cardiac foci of infective endocarditis regardless of the type of valve (native or prosthetic) and also extracardiac localizations related to this pathology (infection…
- Trial name
- DOTENDO (NCT05183555)
- Testing
- 68Ga-DOTATOC PET/CT
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Central Hospital, Nancy, France
Infective Endocarditis
Management of Anemia in Patients with EndocaRditis Infectious Candidates for Cardiac Surgery: the AMERICA Study
Infective endocarditis (EI) is an extremely serious disease requiring prolonged hospitalisation, complex management by multidisciplinary teams and high healthcare costs.
- Trial name
- AMERICA (NCT06583902)
- Testing
- Intravenous iron, Retrospective case-control analysis
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Infective Endocarditis
Prognosis of Patients With Infective Endocarditis and Risk Stratification Value of Biomarkers (ENDEAVOR）
In this study, by establishing a clinical cohort of infective endocarditis, we observed the natural prognosis and influencing factors in the process of disease development and regression; we used multi-omics technology to…
- Trial name
- ENDEAVOR (NCT05965362)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Infective Endocarditis
The Incidence, Clinical Characteristics and Outcome of Infective Endocarditis Among Intravenous Drug Abusers Versus Non-Drug Abusers.
We aim to describe the incidence of IVDA among patients presented with IE, describe their clinical, psychiatric and microbiological characteristics in comparison to non - IVDA, as well as the rate and types of complications and…
- Trial name
- NCT06194409
- Testing
- Echocardiography, Urine analysis , blood culture
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Assiut University
Bacteremia, Infective Endocarditis
Impact of the Blood Culture Technique on the Diagnosis of Infective Endocarditis
To evaluate the performance of a single high volume blood culture sampling strategy versus the actually used multiple sampling strategy for the diagnosis and categorization of infective endocarditis according to the Duke-Li…
- Trial name
- UniEndo (NCT03153384)
- Testing
- Blood Culture
- Where
- 8 sites in France
- Volunteers
- 269 people
- Sponsor
- Central Hospital, Nancy, France
Infective Endocarditis
Partial Oral Antimicrobials to Treat Infective Endocarditis in People Who Inject Drugs
Infective endocarditis (IE) is a serious infection associated with significant morbidity and mortality. Recent studies demonstrated an increased risk of infective endocarditis in people who inject drugs (PWIDs).
- Trial name
- NCT04544306
- Testing
- Partial oral antimicrobial therapy
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Infective Endocarditis
The Predictive Value of Lubricin in Patients With Infective Endocarditis
The main goal of this study is to evaluate the predictability of the disease by measuring the serum lubricin levels in patients with infective endocarditis and in non-patients
- Trial name
- NCT06266741
- Testing
- Lubricin
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Aydin Adnan Menderes University
Infective Endocarditis
Evaluation of a Metabolic Preparation by a Low-carbohydrate Diet as Atkins-diet to Help in Detecting Infective Endocarditis by 18F-FDG PET
Infectious endocarditis (IE) is a pathology where the mortality rate of between 20 and 25%, but a higher morbidity since 50% of the patients are treated by a valvular surgical procedure.
- Trial name
- TEPEIR (NCT03465098)
- Testing
- Strict low carbohydrate diet (< 3gr/day of carbohydrate) before a 18F-FDG PET/CT
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Central Hospital, Nancy, France
Infective Endocarditis, End Stage Renal Disease
Incidence of Infective Endocarditis in End Stage Renal Disease Patients on Hemodialysis by Transesophageal Echocardiography in Assuit University Hospital
1. To detect in more detail the incidence of infective endocarditis in patients with end stage renal disease (ESRD) on hemodialysis. 2.
- Trial name
- NCT05692089
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Infective Endocarditis
Infective Endocarditis in the Elderly
ELDERL-IE is a multicenter national prospective observational study. The main objective is to describe geriatric characteristics (comorbidities, cognitive status, autonomy, nutritional status, balance and walking) in patients…
- Trial name
- ELDERL-IE (NCT02910856)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Central Hospital, Nancy, France