Clinical trials: Emotional Depression
Depressive Symptoms, Anxiety Disorders
Messaging Therapy for Depression and Anxiety: A Longitudinal Effectiveness Study
Therapies delivered via technology have been developed to improve accessibility, however, there is limited research regarding messaging therapy in particular, and none that we know of utilizing a longitudinal effectiveness…
- Trial name
- NCT03699488
- Testing
- psychotherapy via asynchronous message
- Volunteers
- 12,980 people
- Sponsor
- Talkspace
Post-Intensive Care Syndrome, Depressive Symptoms
Pilot Study of a Multidisciplinary Intervention in ICU Survivors at Risk for Psychological or Physical Morbidity
Pilot study of the feasibility and utility of an early, in-hospital multidisciplinary intervention in ICU survivors at risk for psychological and physical problems post-ICU stay
- Conditions
- Post-Intensive Care Syndrome, Depressive Symptoms, Anxiety, Physical Disability
- Trial name
- IMPRESS (NCT06118606)
- Testing
- Case-manager led multidisciplinary follow-up after intensive care
- Where
- 2 sites in Sweden
- Volunteers
- 41 people
- Sponsor
- Region Stockholm
PTSD, Depression
Synchronized Transcranial Magnetic Stimulation for PTSD
The investigators propose a small, two-site, sham-controlled pilot study of synchronized Transcranial Magnetic Stimulation (sTMS) in patients with comorbid post-traumatic stress disorder (PTSD) and depression.
- Trial name
- sTMS (NCT02981381)
- Testing
- NEST-1, NEST-2
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Providence VA Medical Center
Premature Birth, Low Birth Weight
Pilot Trial of CenteringPregnancy With Mindfulness Skills
In the U.S., rates of preterm birth and low birth weight have increased over the past 30 years. Poor birth outcomes are especially high among racial/ethnic minority populations.
- Conditions
- Premature Birth, Low Birth Weight, Postpartum Depression
- Trial name
- NCT01646463
- Testing
- CenteringPregnancy, CenteringPregnancy with Mindfulness Skills
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Post Traumatic Stress Disorder, Adjustment Disorder
Psychological First Aid With Children in a High Risk Group - a Repeated Single Case Design
The purpose of this pilot-study is to evaluate a cognitive behavioral method "Psychological First Aid" used with a group of children (11-16 years) in high risk of developing psychological problems.
- Trial name
- NCT01612104
- Testing
- Psychological First Aid
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- NORCE Norwegian Research Centre AS
Diabetes Mellitus, Stress
Expressive Writing for Reducing Stress and Diabetic Symptoms in Diabetes Patients
This study will determine whether the psychological benefits of expressive writing extend to diabetic patients, how long the benefits will last, and whether additional expressive writing "booster" sessions will lead to greater…
- Conditions
- Diabetes Mellitus, Stress, Depression
- Trial name
- NCT00233142
- Testing
- Expressive writing, Neutral writing
- Where
- 4 sites in United States
- Volunteers
- 187 people
- Sponsor
- Syracuse University
Anxiety Disorder, Depressive Disorder
Efficacy of the Unified Protocol for the Transdiagnostic Treatment (UP-A; Ehrenreich-May et al., 2018) for Adolescents With Moderate Emotional Symptoms in Educational Settings
The main goal is to assess the efficacy of the Unified Protocol for the Transdiagnostic Treatment (UP-A; Ehrenreich-May et al., 2018) for Adolescents with moderate emotional symptoms in educational settings The goal is to prevent…
- Conditions
- Anxiety Disorder, Depressive Disorder, Emotional Problem, Emotional Disorder
- Trial name
- PSICE (NCT05322642)
- Testing
- UPA, Active control condition (Progressive Relaxation Training)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Eduardo Fonseca Pedrero
Depressive Symptoms, Expectations
Combined N-of-1 Trials to Assess Open-Label Placebo Treatment for Antidepressant Discontinuation Symptoms
It has been widely recognized that the placebo effect has a profound impact on treatment outcome in many different conditions. Recent studies imply that this effect appears even if placebos are openly administered; so called…
- Conditions
- Depressive Symptoms, Expectations, Antidepressants
- Trial name
- FAB (NCT05051995)
- Testing
- No-treatment
- Where
- 2 sites in Germany
- Volunteers
- 25 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depression
The Effects of JNJ-39393406 on Psychometric Performance and Residual Depressive
To evaluate the effects of the nicotinic allosteric modulator JNJ-39393406 on psychometric performance and residual depressive symptoms in patients who have been diagnosed with unipolar and bipolar depression but currently DO NOT…
- Trial name
- JNJ-DEP (NCT02677207)
- Testing
- JNJ-39393406
- Where
- 4 sites in Moldova, Romania
- Volunteers
- 80 people
- Sponsor
- Tangent Data
Depressive Symptoms, Quality of Life
Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS
Despite its significant impact on individuals and healthcare systems, substantial gaps remain in the clinical and rehabilitative management of depression in oncology patients.
- Conditions
- Depressive Symptoms, Quality of Life, Cognitive Impairment
- Trial name
- INCEPT (NCT06589544)
- Testing
- Virtual Reality-based Cognitive Remediation (VR-COG) + Treatment as Usual (TAU), Repetitive transcranial magnetic stimulation (rTMS) + Treatment as usual (TAU), Treatment as Usual (TAU)
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University Hospital of Ferrara
Depression, Alcohol, Drinking
Expressive Writing for Co-Occurring Depression and Alcohol Misuse
***Please note that this study does not offer comprehensive treatment program for alcohol abuse or depression. Please do not contact the study staff if you are seeking psychological treatment.
- Trial name
- NCT00818636
- Testing
- Expressive writing (in addition to group therapy as usual).
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Baylor College of Medicine
Emotional Disorders, Childhood Anxiety
Efficacy Study of a Child-centered Version of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Children
The UP-C is a manualized, cognitive-behavioral, and emotion-focused group intervention with a transdiagnostic approach aimed at the treatment of emotional problems (i.e., anxiety and depression) in children aged 7 to 12 years…
- Conditions
- Emotional Disorders, Childhood Anxiety, Childhood Depression
- Trial name
- UP-C/C (NCT05798299)
- Testing
- Arm 1: Transdiagnostic intervention, Arm 2: Anxiety-focused intervention
- Where
- Portugal
- Volunteers
- 94 people
- Sponsor
- University of Lisbon
Stroke, Post-stroke Depression
The Research Team Aims to Elucidate the Impact of ITBS (intermittent Theta Burst Stimulation) on the HPA Axis and Post-stroke Negative Emotions/depression by Conducting Human Experiments That Target Various Brain Regions.
The project team will categorize stroke patients into three groups receiving iTBS stimulation targeting distinct brain regions: the cerebellum, the dorsolateral prefrontal cortex (DLPFC), and the primary motor cortex (M1), with…
- Trial name
- NCT06899893
- Testing
- iTBS
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Stress, Psychological Stress
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
The aim of the Everyday Moments of Mindfulness (EMMI) study is to test whether brief mindfulness-based practices will improve daily psychological stress responses in women (age 30-60) who report a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMI (NCT04606199)
- Testing
- Mindfulness-based intervention, up to 5 minutes 0-3 times/day
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Respiratory Insufficiency, Depression
Behavioral Activation-Rehabilitation to Improve Depressive Symptoms & Physical Function After Acute Respiratory Failure
More and more people are surviving after receiving life support for respiratory failure in the intensive care unit, but these patients often experience problems with depression and physical functioning that lead to reduced…
- Conditions
- Respiratory Insufficiency, Depression, Rehabilitation, Critical Care
- Trial name
- BEHAB (NCT03431493)
- Testing
- Behavioral Activation - Rehabilitation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Johns Hopkins University
Emotional Dysregulation, Therapeutic Alliance
Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth
Emotional dysregulation in justice-involved youth (JIY) is a condition that significantly impacts young people, their families, and juvenile justice and public health systems.
- Conditions
- Emotional Dysregulation, Therapeutic Alliance, Depression Disorder, Anxiety Disorders
- Trial name
- HEAL-SLOJSC (NCT07364799)
- Testing
- Multi-sensory emotional regulation intervention (Heal)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- SoundHeal
Depression, Inflammation
Simvastatin and Emotional Processing (OxSTEP)
Simvastatin is being employed because it is a 'statin'. As a drug class, statins have broad anti-inflammatory properties. Low-level inflammation is thought to be a potentially important mediator of the effects of psychosocial…
- Trial name
- OxSTEP (NCT04973800)
- Testing
- Simvastatin 20mg
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Cognitive Behaviour Therapy
A Clinical Trial of Cognitive Behavior Therapy for Depression, Stigmatization, Excessive Worries, and Emotional Management Among Women Facing Partner Violence
1. Aim to investigate the effectiveness of Cognitive Behavior Therapy for Depression, Stigmatization, Excessive Worries, and Emotional Management among Women Facing Partner Violence 2.
- Trial name
- NCT06208111
- Testing
- cognitive behavioral therapy
- Where
- Pakistan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong
Depressive Symptoms
Ecological Momentary Intervention for Depressive Symptoms in a Community Sample in Hong Kong
The key aim of the study is to test the efficacy of a 4-week ecological momentary intervention (EMI), as compared with the regular weekly-based intervention (control group), in reducing (1) symptoms of depression and (2)…
- Trial name
- NCT04985422
- Testing
- Smartphone-based Daily Ecological Momentary Intervention, Smartphone-based Weekly-delivered Information
- Where
- Hong Kong
- Volunteers
- 262 people
- Sponsor
- The University of Hong Kong