Clinical trials: Emesis
Nausea Gravidarum, Vomiting of Pregnancy
The Effect of Plaster on Nausea-Vomiting During Pregnancy
Hormonal and physical changes during pregnancy can cause nausea and vomiting. Nausea and vomiting are common, especially in the first trimester. The incidence of nausea and vomiting during pregnancy varies between 50% and 80%.
- Conditions
- Nausea Gravidarum, Vomiting of Pregnancy, Pregnancy Related, Acupressure
- Trial name
- NCT05788796
- Testing
- Band-aid application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Abdominal Obesity
The Effect of Intravenous Nalbuphine on PONV With Intrathecal Morphine in Abdominoplasty.
How effectively intravenous nalbuphine can reduce the incidence of PONV after intrathecal administration of morphine in abdominoplastic surgery.
- Trial name
- NCT03786562
- Testing
- Intrathecal Morphine, Intrathecal Morphine + Intravenous Nalbuphine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Neuromuscular Block, Residual, Pain
Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults
This randomized controlled trial aims to compare the effects of intravenous methylprednisolone and dexamethasone on the reversal time of rocuronium by sugammadex in adult patients undergoing elective septoplasty or rhinoplasty.
- Conditions
- Neuromuscular Block, Residual, Pain, Postoperative Nausea
- Trial name
- NCT07187037
- Testing
- Methylprednisolone (MP), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Postoperative Nausea and Vomiting
Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Patients who present for scheduled (non-emergent) cesarean section will be given either intravenous dexamethasone or placebo prior to receiving a duramorph containing spinal anesthetic.
- Trial name
- NCT01734161
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Prolonged QTc Interval
Granisetron Versus Ondansetron: Comparative Effects on ECG, QTc
Postoperative nausea and vomiting [PONV] are common and distressing symptoms after surgery performed under general anaesthesia. 5HT3 antagonists are routinely used for prevention as well as treatment of PONV.
- Trial name
- NCT01352130
- Testing
- Ondansetron, Granisetron
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Tata Memorial Hospital
PONV
Effect of Combination Dexmedetomidine Added to Fentanyl-based Intravenous Patient-controlled Analgesia on Nausea Vomiting in Highly Susceptible Patients Undergoing Lumbar Spinal Surgery: Prospective Double Blinded Randomized Controlled Trial
The aim of this study is to test the hypothesis that addition of dexmedetomidine to fentanyl-based intravenous patient controlled analgesia (PCA) reduces requirement of fentanyl bolus and consequent postoperative nausea and…
- Trial name
- NCT01840254
- Testing
- dexmedetomidine, normal saline
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Peripheral Vascular Disease
Lower Extremity Regional Anesthesia and Infrainguinal Bypass Grafting
In this investigation, the investigators will attempt to demonstrate that patients who have received nerve blocks (regional anesthesia) prior to open surgical vascular bypass of the lower extremities (infrainguinal bypass…
- Trial name
- NCT01803165
- Testing
- Single shot femoral and sciatic nerve block
- Sponsor
- University of Nebraska
Breast Cancer, Drug-induced Nausea and Vomiting
Acupressure in Treating Nausea in Women Receiving Combination Chemotherapy for Breast Cancer
RATIONALE: Acupressure may help to reduce or prevent nausea in patients who are undergoing chemotherapy. It is not yet known whether acupressure plus standard care for nausea is more effective than standard care alone for nausea…
- Trial name
- NCT00046865
- Testing
- acupressure therapy, management of therapy complications, nausea and vomiting therapy
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- M.D. Anderson Cancer Center
Nausea Post Chemotherapy, Vomiting
Pharmacokinetic and Pharmacodynamic Evaluation of Formulations of Δ9-THC
Study based on the pharmacokinetic, pharmacodynamic, safety and stability evaluation of 3 standardized formulations of THC, to be used in healthy volunteers and post-chemotherapy patients as an adjuvant in the symptomatic…
- Conditions
- Nausea Post Chemotherapy, Vomiting, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05272865
- Testing
- Pharmacokinetic and pharmacodynamic profile of THC oral formulations with Dronabinol as comparator
- Where
- Colombia
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- LaSanta S A S
Pain, Nausea
A Study in Opioid-Experienced, Non-Dependent Recreational Drug Users to Determine the Abuse Potential and Safety of CL-108 Tablets Administered Via the Oral Route
The purpose of this study is to assess the abuse potential of CL-108 tablets, including the abuse deterrent effects of promethazine, following oral administration, relative to hydrocodone/acetaminophen (APAP) tablets and placebo…
- Conditions
- Pain, Nausea, Vomiting
- Trial name
- NCT02712554
- Testing
- CL-108, M366
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charleston Laboratories, Inc
Hyperemesis Gravidarum
Does Thiamine Help Vomiting and Nausea in Pregnancy?
There are different treatments for nausea and vomiting in pregnancy. According to the ACOG recommendations, promethazine is the first line of parenteral treatment after oral treatment had failed.
- Trial name
- NCT00861523
- Testing
- thiamine & promethazine
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Nausea and Vomiting Post-foregut Surgery
Reletex Versus Standard of Care Therapy for Post-Operative Nausea Control in Patients Undergoing Foregut Surgery
The effect a ReletexTM device has on postoperative nausea and vomiting when used with ondansetron after foregut surgery will be studied.
- Trial name
- Reletex (NCT01510379)
- Testing
- Reletex, IV ondansetron 4 mg q 6 hours for a total of 4 doses, IV promethazine 25 mg q 6 hours prn
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kyle A Perry
Hematemesis, Portal Hypertension
Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope
Band ligation and injection sclerotherapy are two modalities of treatment that are applied using the endoscope. The purpose of this study is to determine which of two methods is better for controlling bleeding from the upper gut.
- Trial name
- NCT01131962
- Testing
- Endoscopic control of hematemesis
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- University of Alexandria
Nausea, Vomiting
Scopolamine Patch and Acupressure Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean Section
The purpose of this study is to compare the effectiveness of reducing intra-cesarean section nausea and vomiting with regional anesthesia in subjects who will receive scopolamine patch with acupressure point P6 stimulation versus…
- Conditions
- Nausea, Vomiting, Satisfaction
- Trial name
- NCT02960113
- Testing
- scopolamine patch, acupressure point P6
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Cancer Pains
Change the Dose Frequency of Controlled-Release Oxycodone to Refractory Pain
Many patients with cancer experience moderate to severe pain that requires treatment with strong opioids, of which oxycodone and morphine are examples, they are widely applied in clinical treatment because of sustained-released…
- Trial name
- NCT03639415
- Testing
- Increasing the Controlled-Release Oxycodone dose frequency
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Pain, Vomiting
The 4-7-8 Breathing Technique on Pain and Nausea-Vomiting
This study is planned as a randomized controlled trial to determine the effect of the 4-7-8 breathing technique applied to patients after bariatric surgery on pain and nausea and vomiting.
- Conditions
- Pain, Vomiting, Nausea, Post Operative Pain
- Trial name
- Pain (NCT06439121)
- Testing
- 4-7-8 Breathing Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Postoperative Pain, Acute, Postoperative Nausea and Vomiting
The Impact of Breath Exercise Training on Postoperative Pain, Anxiety, and Nausea-Vomiting in General Surgery Patients
This study was conducted to determine the effect of breath exercise on post-operative anxiety level, pain, and nausea-vomiting after general surgery. This was a randomized, controlled experimental study.
- Conditions
- Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Patient Relations, Nurse
- Trial name
- NCT06546514
- Testing
- Breath Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Position Differences, Nutrition
Effect of Cradle Position During Orogastric Tube Feeding on Comfort, Physiological Parameters and Vomiting
The study was planned to determine the effect of the cradle position applied during orogastric tube feeding in premature newborns on comfort, physiological parameters and vomiting frequency.
- Conditions
- Position Differences, Nutrition, Nursing Care
- Trial name
- CRADLE (NCT06759285)
- Testing
- Experimental (cradle position)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Selcuk University
Total Joint Replacement Surgery, Postoperative Nausea and Vomiting
Aromatherapy in Reducing PONV for Total Joint Replacement Patients
This study investigates the effectiveness of aromatherapy in reducing postoperative nausea and vomiting (PONV) among patients undergoing total joint replacement surgery, as these complications can lead to patient discomfort and…
- Trial name
- RCT PONV (NCT07281885)
- Testing
- Aromatherapy patches, Control (Standard treatment)
- Where
- Hong Kong
- Volunteers
- 159 people
- Sponsor
- Hong Kong Buddhist Hospital
Motion Sickness, Postoperative Nausea and Vomiting
Gynecologic Endoscopic Surgery of Female Motion Sickness Patients
The goal of this clinical trial is to compare the analgesic effect of sufentanil and ibuprofen and the incidence of vomiting, and to choose better postoperative analgesic drugs for motion sickness patients.in describe participant…
- Conditions
- Motion Sickness, Postoperative Nausea and Vomiting, Ibuprofen
- Trial name
- NCT06232785
- Testing
- Ibuprofen, sufentanil
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Jilin University