Clinical trials: Emergency Surgery Patients
Hemorrhage
Reversal of Dabigatran Anticoagulant Effect With Idarucizumab
Evaluate the reversal of the anticoagulant effects of dabigatran by IV administration of 5.0g idarucizumab in patients treated with dabigatran etexilate who have uncontrolled bleeding or require emergency surgery or procedures.
- Trial name
- NCT02104947
- Testing
- idarucizumab
- Where
- 176 sites in United States, Argentina and 31 more
- Volunteers
- 503 people
- Sponsor
- Boehringer Ingelheim
Anxiety
The Effect of Virtual Reality Glasses Applied During Emergency Surgical Intervention
This randomized controlled trial evaluates the effect of virtual reality glasses applied during emergency surgical intervention with local anesthesia on patients anxiety.
- Trial name
- Virtual (NCT05253274)
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Mersin University
Patient Presented With Acute Abdomen, Patient Undergoing Urgent GIT Surgery
Conventional VS Enhanced Recovery After Surgery Protocols in Emergency GIT Surgery
Although the ERAS program is widely used in elective procedures in many surgical subspecialties, the place of this program in emergency surgery remains uncertain probably because of the significant challenges in applying all ERAS…
- Trial name
- NCT04584060
- Testing
- ERAS protocols, Early oral feeding, Prophylaxis against DVT
- Volunteers
- 60 people
- Sponsor
- Assiut University
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Surgery, Emergency
Emergency Surgery in the Elderly: Comparison of Frailty Index and Surgical Risk Score
EMERGENCY GENERAL SURGERY IN GERIATRIC PATIENTS: EPIDEMIOLOGY, AND EVALUATION OF FACTORS AFFECTING MORBIDITY AND MORTALITY
- Trial name
- FRAILESEL (NCT02825082)
- Testing
- Abdominal emergency surgery
- Where
- 43 sites in Italy
- Volunteers
- 2,200 people
- Sponsor
- University of Roma La Sapienza
Microcirculatory Diffusion, Microcirculatory Convection Capacity
Association of Microcirculation, Vexus Score and Femoral Vein Doppler in Patients on the ICU After Non-emergency Cardiac Surgery
The aim of the VeMic study is to explore if venous congestion is linked with microcirculatory impairment in elective cardiac surgery patients in the postoperative ICU stay.
- Conditions
- Microcirculatory Diffusion, Microcirculatory Convection Capacity, Venous Congestion, Postoperative Cardiac Surgery
- Trial name
- VeMic (NCT07052461)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland
Cholecystitis, Acute, Cholecystectomy, Laparoscopic
Implementation of RICA (ERAS) Guidelines in Grade II Acute Cholecystitis Undergoing Early Laparoscopic Cholecystectomy
Background Acute cholecystitis (sudden gallbladder inflammation, usually due to gallstones) is a highly frequent surgical emergency.
- Conditions
- Cholecystitis, Acute, Cholecystectomy, Laparoscopic, Enhanced Recovery After Surgery
- Trial name
- COLERICA II (NCT07695922)
- Testing
- RICA Perioperative Care Pathway
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital d'Igualada
Pregnancy Complications, Acute Appendicitis
Fetal Outcomes Among Pregnant Emergency General Surgery Patients
Approximately 1 in 500 pregnant women require non-obstetric surgery. Surgical care for the pregnant woman raises concern for complications adversely affecting pregnancy outcomes.
- Conditions
- Pregnancy Complications, Acute Appendicitis, Acute Cholecystitis, Biliary Pancreatitis
- Trial name
- NCT05085353
- Testing
- non-obstetric acute general surgical disease
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Methodist Health System
Ultrasonography, Lung Diseases
Surgery and Lung Ultrasound in COVID-19 Infection
The first case of COVID-19 was identified on December 19 and the world is actually experiencing a pandemic. The surgical procedure in patients with SARS-CoV-2 infection involves the exposure of other patients and the group of…
- Conditions
- Ultrasonography, Lung Diseases, Surgical Procedure, Covid19
- Trial name
- SOUNDS (NCT04661631)
- Testing
- Lung ultrasound
- Where
- Colombia
- Volunteers
- 451 people
- Sponsor
- Fundacion Clinica Valle del Lili
Aortic Aneurysm, Thoracic, Endothelial Dysfunction
Vasculopathic Injury and Plasma as Endothelial Rescue - OCTAplas Trial (EudraCT no. 2014-000452-28)
Effects of OctaplasLG® on endothelial integrity in patients undergoing emergency surgery for thoracic aortic dissections - a randomized, controlled, single-blinded investigator-initiated pilot trial
- Trial name
- VIPER-OCTA (NCT02253082)
- Testing
- OctaplasLG®, Fresh frozen plasma
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Brain Injuries
Evaluation of Factors That Cause Secondary Brain Damage on Mortality and Morbidity in Patients Undergoing Emergency Surgery Due to Head Trauma.
Traumatic brain injury is combination damage that occurs as a result of a chain reaction of various metabolic events that develop after primary damage caused by trauma.
- Trial name
- NCT04555772
- Testing
- factors evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Hip Fractures, Elderly
Patient Reported Experience Measures Following Hip Fracture Surgery in the Elderly
With an ageing population, hip fractures are likely to become a significant public health burden. Hip fracture surgery is associated with significant morbidity and mortality.
- Conditions
- Hip Fractures, Elderly, Emergency Surgery
- Trial name
- NCT02842996
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Preoperative Screen for Substance Abuse in in Patients Undergoing Emergency Operation
Observational Study of Preoperative Screen for Substance Abuse
Substance abuse is a growing problem world wide, and treatment of substance abusers in the perioperative period, especially for emergency operation is challenging.
- Trial name
- NCT02621411
- Testing
- Substance use
- Where
- China
- Volunteers
- 1,031 people
- Sponsor
- West China Hospital
Emergencies
Validation of Emergency Surgery Score (ESS) in Egyptian Patients Undergoing Emergency Laparotomy
To assess the accuracy of Emergency Surgery Score in predicting postoperative morbidity and mortality in emergency laparotomy.
- Trial name
- NCT05639920
- Testing
- Scoreing
- Volunteers
- 138 people
- Sponsor
- Assiut University
Sepsis
Circulating Stem Cells, SDF-1, HIF-1 and Sepsis's Indices in Emergency Abdominal Surgical Patients
Septic shock is a systemic inflammatory response syndrome with acute circulatory failure secondary to a documented infection. It is the most feared complication in ICU patients, with a 50% mortality rate.
- Trial name
- NCT02589535
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Abdomen, Acute
Clinical Outcomes and Equality in Healthcare for Emergency General Surgery Patients Undergoing Emergency Laparotomy
The goal of this observational cohort study is to evaluate the standard of care for general surgerical patients undergoing emergency laparotomy and assess factors affecting clinical outcomes, as well as evaluating the quality of…
- Trial name
- LAPTOP (NCT05623176)
- Testing
- Standardised laparotomy care
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm
Inguinal Hernia, Acute Appendicitis
The Onset Time of Rocuronium in Emergency and Elective Surgery
Rocuronium, a nondepolarizing neuromuscular blocking agent, is used in general anesthesia to provide conditions for endotracheal intubating.
- Trial name
- NCT02634255
- Testing
- Rocuronium elective surgery, Rocuronium emergency surgery, Propofol
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Surgical Complication, Emergencies
Implementation of an Epidemiological and Clinical Registry of Emergency Surgery Patients in a Costa Rican Hospital
A retrospective cross-sectional study was conducted in a quaternary level university hospital of the Costa Rican public health system.
- Trial name
- NCT05930574
- Testing
- Abdominal surgery
- Where
- Costa Rica
- Volunteers
- 575 people
- Sponsor
- Caja Costarricense de Seguro Social
Covid19, Emergencies
Effect of Covid-19 Pandemic in Non Covid-19 Patients at the Emergency Surgical Department
Introduction Most countries imposed mandatory lockdowns that were rapidly lifted, however Argentina holds the record for one of the longest quarantines in the world.
- Conditions
- Covid19, Emergencies, Appendicitis, Surgical Procedure, Unspecified
- Trial name
- NCT04900233
- Testing
- surgery
- Where
- Argentina
- Volunteers
- 651 people
- Sponsor
- Hospital Italiano de Buenos Aires
Splenic Abscess, Sarcopenia
Sarcopaenia is a Useful Risk Stratification Tool for Surgeons to Prognosticate Splenic Abscess Patients
Sarcopaenia is associated with poor prognoses of in-hospital mortality in splenic abscess patients. Investigators recommend its use by surgeons in the ED to rapidly risk stratify and identify patients requiring urgent and…
- Trial name
- NCT03967041
- Testing
- radiological defined sarcopenia
- Where
- Taiwan
- Volunteers
- 99 people
- Sponsor
- Chang Gung Memorial Hospital