Clinical trials: Emergency Surgery
Emergency Inguinal Hernia Repair, Emergency Ventral Hernia Repair
Emergency Hernia Repair
Emergency hernia repairs are associated with significantly higher morbidity and mortality compared with elective hernia surgery.
- Trial name
- NCT07314398
- Testing
- Emergency hernia repair
- Volunteers
- 600 people
- Sponsor
- Oulu University Hospital
Emergency Colorectal Surgery in Ultra 80 Patients
Colorectal Emergencies in Elderly Patients.
Colon diseases can turn in a clinical emergency with the onset of some important complications. Some critical conditions are more common in aged patients because they are more frails.
- Trial name
- NCT05443386
- Testing
- colorectal surgery
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Foggia
Surgery, Anesthesia
Surgical Capacity in Zimbabwean Public Hospitals
This study aimed to understand how ready Zimbabwe's public hospitals are to perform essential surgeries, which are critical for treating a wide range of health issues from emergencies like car accidents to planned procedures such…
- Trial name
- NCT06358183
- Testing
- No intervention
- Where
- Zimbabwe
- Volunteers
- 80 people
- Sponsor
- Parirenyatwa Hospital
Postoperative Complications, Surgical Site Infection
Hierarchy of Effects of Laboratory Markers and Their Interaction With Comorbidity Concerning Outcome and Personalized Treatment of Trauma Patients in Emergency Care and Rehabilitation
At least ten percent of trauma patients suffer from any sort of complication. The study aims to identify a risk factor profile to early identify trauma patients at risk.
- Conditions
- Postoperative Complications, Surgical Site Infection, Wound Infection, Non-healing Wound
- Trial name
- HELICOPTER (NCT06758427)
- Where
- Germany
- Volunteers
- 2,300 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Postoperative Morbidity, Postoperative Mortality
Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study)
The primary purpose of the study is to evaluate whether the type of fluid (0.9% saline or 6% Hydroxyethyl starch 130/0.4) in the context of an individualized goal-directed fluid therapy is associated with a difference in…
- Trial name
- FLASH (NCT02502773)
- Testing
- Hydroxethyl starch
- Where
- France
- Volunteers
- 826 people
- Sponsor
- University Hospital, Clermont-Ferrand
Surgery, Emergencies
Laparoscopic Versus Open Repair of Peptic Ulcer Perforation
Although laparoscopic repair (LR) of perforated peptic ulcers (PPUs) has long been accepted, clinical evidence comparing LR versus open repair (OR) remains lacking.
- Conditions
- Surgery, Emergencies, Peptic Ulcer Perforation
- Trial name
- LOREPUP (NCT04447170)
- Testing
- Simple repair or Graham technique
- Where
- 13 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Gianluca Costa
Acute Cholecystitis, Biliary Complications
Acute Cholecystitis Biliary Complications - ICG
Acute cholecystitis is a common indication for emergency laparoscopic cholecystectomy. Inflammatory changes and distorted anatomy may increase the risk of biliary complications, including bile duct injury and bile leak, which are…
- Trial name
- ICG-ACBC (NCT07481760)
- Testing
- ICG
- Where
- Spain
- Volunteers
- 296 people
- Sponsor
- Hospital del Mar
Severe Sepsis, Emergency
Impact of Early Goal-directed Fluid Therapy in Septic Patients Undergoing Emergency Surgery
This study wants to compared the safety and efficacy of GDTs using standard pressure-related parameters vs. dynamic hemodynamic indices associated with fluid compartment monitoring, in septic patients requiring emergency surgery.
- Conditions
- Severe Sepsis, Emergency, Surgery
- Trial name
- NCT01654003
- Testing
- CONTROL, OPTIMIZED
- Where
- 2 sites in Switzerland
- Volunteers
- 20 people
- Sponsor
- University Hospital, Geneva
Colorectal Cancer
Emergency Surgery Versus Colorectal Stents for the Management of Malignant Colonic Obstructions
The study evaluates and compares effect of emergency surgery and colonic stents for treatment of malignant colonic obstructions.
- Trial name
- NCT04449822
- Testing
- Emergency surgery, Colonic stenting
- Where
- Georgia
- Volunteers
- 40 people
- Sponsor
- Zaza Demetrashvili
Acute Appendicitis, Acute Appendicitis With Rupture
Modified Enhanced Recovery Program in Emergency Surgery (MERES)
Laparoscopic appendectomy (LA) is a widespread surgical procedure. Patients may develop considerable postoperative pain and dyspepsia resulting in prolong in-hospital stay.
- Conditions
- Acute Appendicitis, Acute Appendicitis With Rupture, Acute Appendicitis With Peritonitis, Acute Appendicitis Without Peritonitis
- Trial name
- MERES (NCT03754777)
- Testing
- Laparoscopic appendectomy
- Where
- Russia
- Volunteers
- 122 people
- Sponsor
- Pirogov Russian National Research Medical University
Pain, Postoperative, Abdominal Surgery
Erector Spinae Plane Block Versus Oblique-Subcostal Transversus Abdominis Plane Block in Emergency Abdominal Surgery with Midline Incision
Most of the recommendations regarding pain management in emergency abdominal surgery are extracted from data from elective abdominal surgery.
- Conditions
- Pain, Postoperative, Abdominal Surgery, Emergency
- Trial name
- NCT06448299
- Testing
- TAPB, ESPB
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Kasr El Aini Hospital
Airway Complication of Anesthesia
Prevalence of Major Vessels Underlying the Potential Incision Site for Emergency Front of Neck Airway Access in Adult Surgical Patients With Impalpable Neck Anatomy
Patients undergoing general anesthesia require assistance with their breathing and with the delivery of oxygen to their lungs. To achieve this, an anesthesiologist inserts a type of plastic breathing tube into the airway via the…
- Trial name
- NCT06637319
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Emergency Surgery, Full Stomach
Assessment of Prokinetic Effects of Erythromycin in Emergency Patients With a Full Stomach
The aims of the study is to assess whether the intravenous infusion of 3 mg/kg erythromycin has a significant gastrokinetic effect leading to empty the stomach in less than 90 minutes in non-fasting patients undergoing emergency…
- Trial name
- NCT02296866
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Lionel Bouvet
Surgery--Complications, Abdomen Disease
Use of Wearables for Early Detection of Complications After Major Acute Abdominal Surgery
The purpose of the study is to investigate whether glucose profile, sleep disturbances and heart rate variability measured with wearable devices is associated with postoperative recovery and complications within 30 days after…
- Trial name
- NCT04257344
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital
Mortality, Pediatric
Operative Duration as a Predictor of Mortality in Pediatric Emergency Surgery
Introduction Operative duration is an important but under-studied predictor of mortality in emergency laparotomies. Aims \& Objectives The objective of this study was to quantify the effect of duration of emergency laparotomy in…
- Conditions
- Mortality, Pediatric, Laparotomy, Emergencies
- Trial name
- NCT03270930
- Testing
- Emergency laparotomy
- Volunteers
- 213 people
- Sponsor
- Jawaharlal Nehru Medical College
Surgical Wound
Comparison of Interrupted Suturing Versus Continuous Suturing in Laparotomy Wound Closed.
Emergency laparotomy is associated with high morbidity, particularly due to wound dehiscence and infection. Choosing an optimal suturing technique can significantly impact patient outcomes, but data on the comparison of…
- Trial name
- NCT07601919
- Testing
- Interrupted Closure, Continuous Closure
- Where
- Pakistan
- Volunteers
- 184 people
- Sponsor
- Muhammad Aamir Latif
Educational Problems, Orthopedic Disorder
Assessment of an Orthopedic Surgery Rotation on Musculoskeletal Competency in Emergency Medicine Residency Training
Patient commonly present with orthopedic injuries in the emergency department. Musculoskeletal education has not historically been emphasized in American medical schools, and the effectiveness of an orthopedic surgery rotation…
- Conditions
- Educational Problems, Orthopedic Disorder, Emergencies
- Trial name
- NCT03944746
- Testing
- Education Curriculum
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Jared L. Cohen
Emergency Surgery
Preoperative Rapid Pou Ultrasound Assessment in Critically Ill Patients Undergoing Emergency Surgery
With the development of society, the number of emergency critical operations is increasing year by year. Traditionally, the patient's systemic and circulatory status is indirectly assessed by testing and blood pressure heart…
- Trial name
- NCT04111783
- Testing
- POU protocol ultrasound
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shenzhen People's Hospital
Laparotomy, Dehiscence Wound
Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT
This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory…
- Conditions
- Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen
- Trial name
- NCT06043414
- Testing
- triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Southern California
Acute Diverticulitis
The COLD2B Multicenter, Two-arm Prospective Cohort Study
Since it is still debated whether 2b acute diverticulitis (AD), according to the World Society of Emergency Surgery (WSES) classification, should be initially treated surgically or conservatively, the COLD2B study has been…
- Trial name
- COLD2B (NCT06388538)
- Testing
- Conservative treatment (non-operative treatment), Surgical treatment (operative treatment)
- Where
- 4 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Azienda Sanitaria di Firenze