Clinical trials: Emergency Medicine, open to volunteers
Insomnia, Nightmares Associated With Trauma and Stress
Restorative Early Sleep Treatment After the Emergency Department
The goal of this randomized controlled trial is to pilot the virtual delivery of cognitive behavioral therapy for insomnia (CBT-I) and nightmares (CBT-I\&N) via telehealth as an early intervention for treating posttraumatic sleep…
- Conditions
- Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
- Trial name
- RESTED (NCT07121270)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Healthy Volunteers
Ultrasound to View Abdominal Wall Muscle Layers
The American College of Emergency Physicians (ACEP) views ultrasound-guided nerve blocks to be a core skill for emergency medicine physicians.
- Trial name
- NCT06955013
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Pneumonia, Fungal Pneumonia
Derivation and Validation of the Fungal Pneumonia Assessment and Likelihood Predictor Score
The FUNGAL-P study is a single-center observational study designed to derive and validate a clinical prediction score for the early identification of fungal pneumonia in adult patients presenting with pneumonia.
- Conditions
- Pneumonia, Fungal Pneumonia, Aspergillosis Pneumonia, Pulmonary Aspergillosis
- Trial name
- FUNGAL-P (NCT07681583)
- Testing
- FUNGAL-P Score Assessment
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Charcoal, Decontamination, Poisoning
Activated CHARcoal in Poisoned Patient - Pilot Trial
The goal of this clinical pilot trial is to determine the feasibility of the clinical trial. Then the large-scale CHARPP will be conducted in order to determine the efficacity of activated charcoal as a treatment for acute…
- Trial name
- CHARPP-Pilot (NCT05471479)
- Testing
- Activated Charcoal, No activated charcoal
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Infarction
Myocardial Infarction Safe Emergency Medicine Accompanying Study: Providing Reperfusion Therapy Within the Recommended Time Limits
The project is a prospective observational study with the aim of system improvement. It represents accompanying research in connection with the implementation of Safe Emergency Medicine , - an initiative under the auspices of the…
- Trial name
- NCT07092904
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University Hospital of North Norway
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Craniocerebral Trauma, Brain Injuries, Traumatic
Socio-Cultural Level, Health Literacy, and Parental CT Demand in Paediatric Minor Head Trauma
Minor head trauma is one of the most frequent reasons for paediatric emergency department visits worldwide. The PECARN (Paediatric Emergency Care Applied Research Network) clinical decision rule stratifies children with minor…
- Conditions
- Craniocerebral Trauma, Brain Injuries, Traumatic, Head Injuries, Closed
- Trial name
- NCT07655310
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Opioid-use Disorder, Opioid Dependence
Young Houston Emergency Opioid Engagement System
The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral…
- Conditions
- Opioid-use Disorder, Opioid Dependence, Opioid Overdose, Opioid Use
- Trial name
- YHEROES (NCT04811014)
- Testing
- Buprenorphine, Naloxone Drug Combination, Individual Counseling, Peer Recovery Support Services
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- The University of Texas Health Science Center, Houston
Emergency Medicine, POCUS
Point-of-Care Ultrasound for Diagnosing Abdominal Pain in the Emergency Department
The goal of this clinical trial is to learn if adding an abdominal ultrasound scan to the standard examination helps emergency physicians make a correct diagnosis in adults with acute abdominal pain in the emergency department.
- Conditions
- Emergency Medicine, POCUS, Abdominal Pain (AP), Acute Abdominal Pain
- Trial name
- AbdoPOCUS (NCT07849569)
- Testing
- Point of care ultrasound
- Where
- 3 sites in Denmark
- Volunteers
- 508 people
- Sponsor
- University of Aarhus
Cardiac Arrest, Out-Of-Hospital, Cardiac Arrest Due to Underlying Cardiac Condition
AID-OMIE - Artificial Intelligence in Detection of Occlusive Myocardial Infarction in Emergency Medicine
Study Objective and Hypothesis The study hypothesizes that artificial intelligence (AI)-assisted interpretation of the 12-lead electrocardiogram (ECG) can improve the care of patients resuscitated after out-of-hospital cardiac…
- Trial name
- AID-OMIE (NCT06767709)
- Volunteers
- 200 people
- Sponsor
- Institute of Mountain Emergency Medicine
Pulmonary Embolism, D-dimer
Emergency Medicine Pulmonary Embolism Testing Multicentre Study
It is important to diagnose pulmonary embolism in a timely manner to prevent death and long-term disability. More than half a million people (4-5% of emergency department patients) are tested for pulmonary embolism, although the…
- Conditions
- Pulmonary Embolism, D-dimer, Diagnosis
- Trial name
- EMPET (NCT06320236)
- Testing
- Adjust-Unlikely
- Where
- 4 sites in Canada
- Volunteers
- 4,000 people
- Sponsor
- Dr. Kerstin de Wit
Atrial Fibrillation (AF)
Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation
The goal of this observational study is to better understand the role of measuring troponin (a protein measured by a blood test) and coronary imaging in patients presenting with rapid atrial fibrillation (AF) The main questions…
- Trial name
- Mi-AF (NCT06951100)
- Testing
- CT coronary angiography
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Edinburgh
Anemia
Phenotyping Acute Non-Severe Anemia in the Emergency Department
Anemia is traditionally diagnosed and managed using circulating hemoglobin concentration ([Hb]). However, [Hb] is influenced by plasma volume and may not accurately reflect the total amount of hemoglobin available for oxygen…
- Trial name
- PHENOEMEMIA (NCT07761104)
- Testing
- Total hemoglobin mass measurement, Focused transthoracic echocardiography, Near-infrared spectroscopy
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Hospices Civils de Lyon
Fever, Triage
Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department
This multicenter prospective observational cohort study evaluates how well the initial triage category assigned by the Turkish Ministry of Health three-level color-coded triage system (Red-Yellow-Green) predicts serious clinical…
- Conditions
- Fever, Triage, Pediatric Emergency Medicine, Serious Bacterial Infection
- Trial name
- PEDTRIAGE (NCT07739004)
- Testing
- Ministry of Health three-level color-coded triage
- Where
- 10 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people
- Sponsor
- TC Erciyes University
Tracheal Intubation, Medical Education
Application of PDCA Cycle in Tracheal Intubation Training for Emergency Medicine Residents
Tracheal intubation is a critical but technically demanding procedure in emergency airway management. Junior emergency medicine residents often struggle to achieve proficiency, leading to increased risks of complications.
- Trial name
- PACT (NCT07146984)
- Testing
- Behavioral (Educational Training Program)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou Panyu Central Hospital
Asthmatic Patients, MDI
Assessment of Emergency Spacers Versus Traditional Spacers for Delivery of Aerosolized Drugs
The goal of this clinical trial is to evaluate the performance, feasibility, and safety of emergency spacers compared to traditional spacers for the delivery of aerosolized drugs using pMDI.
- Conditions
- Asthmatic Patients, MDI, Aerosol Generating Procedure
- Trial name
- NCT06816342
- Testing
- Ventoline® Evohaler® 100 µg/inhalation pMDI alone, Ventoline® Evohaler® 100 µg/inhalation pMDI connected to Able spacer, Ventoline® Evohaler® 100 µg/inhalation pMDI connectec to Tips-Haler spacer
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Pediatric Emergency Medicine, Therapeutic Turnaround Time
Effectiveness of a Mobile App in Reducing Therapeutic TAT in an Emergency Department
This study is a single center, non-equivalent comparison group, pre-post study in a tertiary pediatric emergency department in Switzerland.
- Trial name
- NCT05557331
- Testing
- PIMPmyHospital (mobile app)
- Where
- 2 sites in Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Renal Colic
Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation and Dexketoprofen in Renal Colic
The aim of this study was to compare the analgesic efficacy of transcutaneous electrical nerve stimulation (TENS) and dexketoprofen trometamol in patients presenting to the emergency department due to renal colic.
- Trial name
- NCT07176572
- Testing
- TENS, Dexketoprofen Trometamol
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Adiyaman University Research Hospital
Point of Care Ultrasound (POCUS), Ultrasound Exam in Emergency/Medical Care
Evaluation of an Online Application for Point of Care Ultrasound Training in General Internal Medicine Residents
This study compares Point of Care Ultrasound (POCUS) training in two hospitals, one that uses an online application for supervision and one that does not use the application.
- Conditions
- Point of Care Ultrasound (POCUS), Ultrasound Exam in Emergency/Medical Care, Ultrasound Evaluation
- Trial name
- NCT07372053
- Where
- 2 sites in Switzerland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Baden
Emergency Department Visit
Automatic Detection of Eligible Patients to RAUC Protocol (RAUCISABLE)
The augmented rehabilitation of emergency surgeries (ARES, RAUC in French) is a research program supported by Amiens-Picardy University Hospital and the University of Picardy Jules Verne.
- Trial name
- RAUCISABLE (NCT07037719)
- Where
- France
- Volunteers
- 300,000 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens