Clinical trials: Emergencies
Acute Pain
ESKetamine Low-dose vs Ketamine Low-dose for Severe Acute Pain in Emergency Units, Comparison of PsychodyslEptic Effects
Almost 30% of painful patients in emergency departments (ED) describe their pain as severe (i.e. a Verbal Numerical Rating Score VNRS ≥ 6 on a scale ranging from 0 to 10).
- Trial name
- ESKAPE (NCT06853041)
- Testing
- Esketamine, Ketamine
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pulmonary Disease, Chronic Obstructive
Magnesium Sulfate to Prevent Hospitalisation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
The purpose of this study is to assess whether administration of a bolus dose of MgSO4 (magnesium sulfate) plus standard therapy is superior to standard therapy alone for the management of Acute Exacerbations of Chronic Pulmonary…
- Trial name
- NCT02498496
- Testing
- Magnesium Sulfate
- Sponsor
- Hôpital de Verdun
Medical Informatics, Pediatric Emergency Medicine
Mobile Chat Service for Parents of Children in Pediatric Emergency Room
The goal of this clinical trial is to test giving all medical/non-medical information in the pediatric emergency room(ER). Main questions it aims to answer are: Does providing medical/non-medical information to parents of…
- Conditions
- Medical Informatics, Pediatric Emergency Medicine, Emergency Medicine
- Trial name
- NCT06002542
- Testing
- Information provided, Control
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Kidney Stone
An Analgesia Protocol for Acute Renal Colic in the Emergency Department
An analgesia protocol for acute renal colic will lead to faster significant reductions in pain than prior practice.
- Trial name
- NCT00504283
- Testing
- Toradol, Morphine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pain, EMERGENCY MEDICINE
Comparative Study on Acute Pain Evaluation Between Spanish and French Hospital Emergency Unit
Today, pain is a difficult affordable subject in Spain. There are however 187 units of pain care with a consultations rate in emergency center of more than 60%.For example OXYCODONE(opioid analgesic)is widely used while it's…
- Trial name
- DASAU (NCT02973568)
- Testing
- Observational Study
- Where
- France
- Volunteers
- 641 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Emergencies
the Role of Laparoscopy in Lower Gastrointestinal Surgical Emergencies in Adults.
Introduction: causes of lower abdominal pain caused by various GIT emergencies, including acute appendicitis, intestinal obstruction, acute perforated diverticulitis, obstructed hernia, and iatrogenic colon perforation.
- Trial name
- NCT05584579
- Testing
- laparoscopic surgery
- Where
- Egypt
- Volunteers
- 793 people
- Sponsor
- Zagazig University
Acute Kidney Injury KDIGO 3, Continuous Renal Replacement Therapy Initiated by the Clinician in Charge Without Emergency
Is Myocardial Stunning Induced by Continuous Renal Replacement Therapy a Reality in Critically Ill Patients?
Myocardial stunning during chronic intermittent hemodialysis is a well-described phenomenon. Little case series of patients presenting myocardial stunning during renal replacement therapy for acute kidney injury in critically ill…
- Conditions
- Acute Kidney Injury KDIGO 3, Continuous Renal Replacement Therapy Initiated by the Clinician in Charge Without Emergency, Myocardial Stunning
- Trial name
- MS-CRRT (NCT05209230)
- Testing
- Continuous renal replacement therapy, Control group
- Where
- 3 sites in France
- Volunteers
- 42 people
- Sponsor
- Hospices Civils de Lyon
Emergency, Orotracheal Intubation
Pilot Study on the Use of Video Laryngoscopy in Pre-hospital Settings
Management of the upper airways is an essential skill in pre-hospital medicine in order to protect the respiratory tract and optimise ventilation and oxygenation.
- Trial name
- VIDEOPREHOSP (NCT07630467)
- Testing
- Videolaryngoscopy in first attempt in prehospital with AirTraq
- Where
- France
- Volunteers
- 143 people
- Sponsor
- Centre Hospitalier de Valenciennes
Respiratory Tract Infections
PREDICATE Trial For Respiratory Tract Infections
Background The goal of this clinical trial is to learn if prednisolone works to treat moderate to severe respiratory tract infections in adults admitted to hospital.
- Trial name
- NCT06472219
- Testing
- Prednisolone 30 mg
- Where
- Hong Kong
- Volunteers
- 1,300 people
- Sponsor
- The University of Hong Kong
Cholecystitis, Acute, Biliary Diseases
Repeat Biliary Point of Care Ultrasound for Detecting Early Acute Cholecystitis
The goal of this interventional, prospective study is to determine the clinical utility of a repeat point-of-care ultrasound of the gallbladder in adult emergency department patients with abdominal pain for which initial imaging…
- Trial name
- NCT07792200
- Testing
- Repeat biliary point of care ultrasound
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- WellSpan Health
Severely Traumatized Patients in Emergency Wards
Interest of the Ultrasound Guidance for the Laying of Femoral Arterial and Venous Catheters in Intensive Care Unit
The femoral approach is the preferred vascular access for the set-up of emergency catheters in severely traumatized patient. This location combines simplicity and speed of installation, it allows the simultaneous set-up of…
- Trial name
- ECHOGUIDE (NCT02820909)
- Testing
- venous and arterial catheter set-up using ultrasound guidance, Anatomical guidance.
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Hospices Civils de Lyon
Gonorrhea, Chlamydia
Adolescent Sexually Transmitted Infection Screening in the Emergency Department
Sexually transmitted infections (STIs) are highly prevalent among adolescents. Clinical practices related to screening, diagnosis, treatment, and prevention of STIs among adolescents are suboptimal.
- Trial name
- STI (NCT03715335)
- Testing
- Targeted STI Screening, Universally Offered STI Screening
- Where
- 5 sites in United States
- Volunteers
- 98,413 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Severe Dyspnea, CAPD
BIOmarkers of Dyspnea IN Emergency Room
The purpose of this study is to evaluate the capacity of some novels biomarkers Procalcitonin (PCT), Midregional Proadrenomedullin (MR pro ADM), Midregional pro-atrial natriuretic peptide (MR pro ANP), Copeptin (CT pro arginine…
- Conditions
- Severe Dyspnea, CAPD, AE COPD, Acute Heart Failure
- Trial name
- BIODINER (NCT01227317)
- Testing
- Prognostic value of Biomarkers
- Where
- France
- Volunteers
- 444 people
- Sponsor
- ThermoFisher Scientific Brahms Biomarkers France
Pregnancy in Adolescence, Counseling
Reducing Adolescent Pregnancy
This multi-site study is employing a brief contraception counseling intervention in the Emergency Department (ED) to shed light on factors that affect decision making as well as barriers and facilitators to conception initiation…
- Conditions
- Pregnancy in Adolescence, Counseling, Contraception Behavior
- Trial name
- NCT04120376
- Testing
- Contraception Counseling
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Traumatic Brain Injury
Role of Combined Therapy of Propranolol and Gabapentin in Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury
Paroxysmal sympathetic hyperactivity (PSH) is a syndrome that comprises a series of signs and symptoms reflecting exacerbated sympathetic activity, including arterial hypertension, fever, tachycardia, generalized perspiration…
- Trial name
- NCT05427474
- Testing
- Propranolol , gabapentin
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Anxiety
Music in the Emergency Department (ED)
This will be a randomized controlled study evaluating the effect of a music-listening intervention compared to standard care (control) during patient visit to the emergency department (ED).
- Trial name
- NCT03047915
- Testing
- Music
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Columbia University
Trauma
Relevance of Whole-body Computed Tomography Prescription in the Emergency Department : an Identification Tool for Low Risk Patients
The whole-body scanner (SCE) is a powerful examination that guides the management of patients severely traumatized. However, the systematic use of this examination in emergency departments is responsible for a large proportion of…
- Trial name
- PRE-SCEAU (NCT05588791)
- Testing
- whole-body computed tomography
- Where
- France
- Volunteers
- 2,018 people
- Sponsor
- University Hospital, Rouen
Surgical Complication, Emergencies
Implementation of an Epidemiological and Clinical Registry of Emergency Surgery Patients in a Costa Rican Hospital
A retrospective cross-sectional study was conducted in a quaternary level university hospital of the Costa Rican public health system.
- Trial name
- NCT05930574
- Testing
- Abdominal surgery
- Where
- Costa Rica
- Volunteers
- 575 people
- Sponsor
- Caja Costarricense de Seguro Social
Gallbladder Diseases
Emergency Ultrasound of the Gallbladder
The purpose of this study is to determine whether fasting for 8 hours prior to ultrasonography for cholelithiasis (gallbladder pain) is needed.
- Trial name
- NCT00388830
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Dyspnea
Evaluation of the Impact of Lung Ultrasound on Mortality and Rehospitalization in Patients Admitted to the Emergency Department With Dyspnea
Dyspnea is a frequent reason for referral to emergency departments, leading to a 30-day mortality rate of up to 10% and a 3-month rehospitalization rate of over 30%.
- Trial name
- HOSPITALUS (NCT05787665)
- Testing
- phone call at 3 months
- Where
- France
- Volunteers
- 385 people
- Sponsor
- Hospices Civils de Lyon