Clinical trials: Emergencies
Ebola Virus Disease
Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola)
The purpose of this study is to evaluate the efficacy and safety of amiodarone in the treatment of patients afflicted with Ebola virus disease.
- Trial name
- EASE (NCT02307591)
- Testing
- Best Supportive Care, Best Supportive Care + Amiodarone
- Sponsor
- Emergency NGO Onlus
Social Determinants of Health
Social Needs Screenings in ED
This study will determine whether existing Health Information Technology can be leveraged to 1) implement a universal, patient-centered social needs assessment and referral process during routine Emergency Department care; 2)…
- Trial name
- NCT04630041
- Testing
- 211 Referral
- Where
- United States
- Volunteers
- 5,081 people
- Sponsor
- Andrea Wallace
Fall, Fall Injury
Geriatric Emergency Department Fall Injury Prevention Project
This prospective randomized study will assess an emergency department (ED) based prevention strategy in geriatric patients at high risk for recurrent falls and injury.
- Conditions
- Fall, Fall Injury, Emergencies
- Trial name
- GREAT-FALL (NCT05807724)
- Testing
- Phone-based fall-prevention strategy, Home-visit fall prevention strategy
- Where
- United States
- Volunteers
- 644 people
- Sponsor
- Florida Atlantic University
Asthma
Evaluation of the Written Information Delivered by the General Practitioner of the Patients Presenting to the Emergency Room for an Aggravation of Asthma
Asthma is a common pathology (prevalence 6.4% in 2018, in France), currently managed by the general practitioner in general practice. It is a chronic disease at risk of exacerbation, which can lead to the use of care.
- Trial name
- ASTHMAVILLE (NCT04048746)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Asthma Exacerbation, Emergency Department
Efficacy of High-Dose Continuous Intravenous Magnesium Sulfate Infusion vs Standard Intravenous Magnesium Sulfate Therapy in Status Asthmaticus in the ED
The goal of this clinical is to compare treatment outcomes between high dose continuous IV Magnesium and standard therapy in the management of acute exacerbation of asthma in the emergency department.
- Conditions
- Asthma Exacerbation, Emergency Department, Magnesuim Sulfate, High Dose
- Trial name
- HIMAG-ED-STAT (NCT07795970)
- Testing
- ้High-dose Magnesium sulphate, standard-dose Magnesium Sulfate
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Information Structuring Skills, Empathy Skills
Improving Discharge Communication in the Emergency Department Through Information Structuring
The goal of the proposed study is to assess the potential of information structuring for improving discharge communication. Specifically, the investigators aim to examine the advantages of an information-structuring skills…
- Trial name
- NCT02468869
- Testing
- Communication skills training "empathy skills", Communication skills training "information structuring skills"
- Where
- Switzerland
- Volunteers
- 196 people
- Sponsor
- University Hospital, Basel, Switzerland
Heart Failure
Improving Risk Stratification of Emergency Department Patients With Acute Heart Failure
The primary goal is to build and test a previously developed and validated risk model and clinical decision support tool embedded within the electronic health record to improve risk stratification of emergency department (ED)…
- Trial name
- NCT06065761
- Testing
- Comprehensive ED heart failure management tool
- Where
- 21 sites in United States
- Volunteers
- 17,459 people
- Sponsor
- Kaiser Permanente
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Elective Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after elective surgery.
- Trial name
- NCT04929886
- Where
- 5 sites in China
- Volunteers
- 1,000,000 people
- Sponsor
- Huazhong University of Science and Technology
Geriatrics
Continuity of the Therapeutic Limitation Code: Analysis of the Variables of Admission in the Emergency Service That Are Associated With a Therapeutic Limitation Upon Exit
Demographically, the geriatric population is expanding. It is also increasingly found in the emergency services.However, emergency services are not designed to accommodate these patients, whose needs are specific.
- Trial name
- NCT02682979
- Testing
- Medical files analysis
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Brugmann University Hospital
Opioid Dependence
Comparing Interventions for Opioid Dependent Patients Presenting in Medical Emergency Departments
This study will compare the effects of brief strengths-based case management (SBCM) to the effects of screening, assessment and referral alone (SAR) in opioid-dependent patients.
- Trial name
- NCT02586896
- Testing
- Strengths-based Case Management (SBCM), Screening, Assessment, and Referral (SAR)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- NYU Langone Health
Emergency Department Visit
Wisconsin Evaluation of Emergency Department Care Coordination
The State of Wisconsin is now expanding its investment in care coordination models as an effort to reduce inappropriate hospital emergency department (ED) use, improve health outcomes, and reduce Medicaid expenditures.
- Trial name
- NCT04550169
- Testing
- Intensive Care Coordination
- Where
- 4 sites in United States
- Volunteers
- 3,405 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Severe Traumatic Pain, Numeric Pain Rating Scale > 5 / 10
Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting
Intranasal (IN) administration of opiates is an appealing non-invasive way of treating acute traumatic pain in prehospital and Emergency departments (ED).
- Trial name
- ALGOFINE-2 (NCT02095366)
- Testing
- Morphine, Sufentanil
- Where
- 6 sites in France
- Volunteers
- 194 people
- Sponsor
- University Hospital, Grenoble
Emergencies, Trauma
Traumatic Characteristics of the Forensic Cases Admitted to Emergency Department and Errors in the Forensic Reports
Objectives: to detect the mistakes and deficiencies of the forensic reports which was written and to detect the injury characteristics of the forensic cases applied to emergency service of a tertiary hospital.
- Trial name
- NCT03133702
- Testing
- Forensic cases
- Where
- Turkey (Türkiye)
- Volunteers
- 4,300 people
- Sponsor
- Adiyaman University Research Hospital
Anxiety, Lacerations
Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department
Laceration repair can cause significant anxiety in children. As open wounds account for 21-25% of injuries in children presenting to the emergency department, the management of anxiety is of great importance.
- Trial name
- NCT02618772
- Testing
- Midazolam, Saline
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Medication Reconciliation, Emergency Department
Medication Histories Conducted by Nurses (RNs), Pharmacy Techs (CPhTs) & Pharmacists (RPhs)
Up to 50% of medication errors and 20% of adverse drug reactions (ADRs) in the hospital setting are estimated to be related to communication issues regarding patient medications at various transition points of care from admission…
- Trial name
- NCT01065675
- Testing
- Medication reconciliation completed by a RN, CPhT, or RPh
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Wesley Medical Center
Gynecologic Disease
Evaluation of the Rate of Consultations in Gynecological Emergencies Under "Non-urgent" Management
The difference between the demand and the current medical supply poses a real public health problem in terms of the organization of health care systems.
- Trial name
- URGO_CARE (NCT05325619)
- Where
- France
- Volunteers
- 809 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Intubation in Intensive Care Units
Delayed Against Rapid Sequence Induction in Adults With Medical Diseases Undergoing Emergency Endotracheal Intubation.
The goal of this clinical trial is to learn if it is feaseble to conduct a superiority trial comparing two methods for endotracheal intubation in critically ill patients.
- Trial name
- DARSITUBE (NCT06940219)
- Testing
- Delayed Sequence Induction, Modified Rapid Sequence Induction
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Leipzig University Medical Center
Pain, Diabetes Mellitus
Cold Spray for Insulin-Injection Pain in the Emergency Department
This randomized, double-blind, placebo-controlled, within-patient crossover trial evaluated whether a vapocoolant (cold) spray applied before subcutaneous insulin injection reduces injection pain compared with a placebo…
- Trial name
- NCT07728162
- Testing
- Cold (vapocoolant) spray
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Abant Izzet Baysal University
Fever, Respiratory Tract Infections
Diagnostic Accuracy of a Host-response Based Diagnostic Tool for Distinguishing Between Bacterial and Viral Etiologies in Pediatric Patients
This is a prospective clinical validation study of a novel regulatory approved (CE-IVD) diagnostic assay called ImmunoXpert™ that will enroll 1222 pediatric patients.
- Trial name
- AutoPilot (NCT03052088)
- Where
- 2 sites in Germany, Italy
- Volunteers
- 1,140 people
- Sponsor
- MeMed Diagnostics Ltd.
Ankle Sprains
Evaluation of the Recovery Experienced by Patients After an Ankle Sprain Treated in the Emergency Department of Nantes University Hospital
To evaluate the recovery experienced by patients with ankle sprains treated in the adult emergency department of Nantes University Hospital.
- Trial name
- ANKHEAL (NCT06657937)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Nantes University Hospital