Clinical trials: Electrophysiology
Atrial Fibrillation, Atrial Tachyarrhythmia
LEAF - Low Energy In Atrial Fibrillation
The purpose of the study is to demonstrate the efficiency on AT / AF prevention and termination of a new algorithm contained in the Medtronic AT500 Antitachycardia device in patients with conventional pacemaker indications.
- Trial name
- NCT00157781
- Testing
- Medtronic AT500
- Volunteers
- 237 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Atrial Fibrillation, Atrial Fibrillation Paroxysmal
Early Diagnosis of Atrial Fibrillation in the Wait-Time Prior to Seeing a Cardiologist
A randomized patient-oriented trial to investigate whether continual symptomatic use of the Kardia Mobile monitoring device is a superior strategy for diagnosing Atrial Fibrillation (AF) in comparison to normal ambulatory…
- Conditions
- Atrial Fibrillation, Atrial Fibrillation Paroxysmal, Arrhythmias, Cardiac, Cardiovascular Diseases
- Trial name
- CATCH-AF (NCT04302311)
- Testing
- Holter monitoring, Kardia/AliveCor monitoring
- Where
- Canada
- Volunteers
- 73 people
- Sponsor
- Victoria Cardiac Arrhythmia Trials
Fear, PTSD
Investigations of Amygdala Function Using Neurophysiological Recording and Stimulation
This study aims to specifically examine the in vivo electrophysiology and effects of direct stimulation of the human amygdala during conditioned and evoked fear.
- Conditions
- Fear, PTSD, Panic Disorder
- Trial name
- NCT03958903
- Testing
- Amygdala recording and stimulation using Neuropace RNS, Behavioral tasks
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Stanford University
Ventricular Tachycardia, Cardiovascular Diseases
Genetic Substudy of the Alternans Before Cardioverter Defibrillator (ABCD) Trial
The ABCD clinical study (ClinicalTrials.gov Identifier NCT00187291) was designed to determine if a T-Wave Alternans (TWA) test is equivalent to an Electrophysiology Study (EPS) in predicting life-threatening heart rhythms in…
- Conditions
- Ventricular Tachycardia, Cardiovascular Diseases, Arrythmia, CVD
- Trial name
- ABCD (NCT00583297)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- CardioDx
Electrical Stimulation of Nerves Produces Muscle Reflexes
Effects of Uremia on Brachial Plexus Electrophysiology and Brachial Plexus Block
As a late stage of renal failure, uremia not only leads to severe impairment of renal function in patients, but also often leads to a variety of complications, among which multiple peripheral neuropathy is particularly common.
- Trial name
- NCT06931756
- Testing
- Neural Stimulator
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Cardiac Arrhythmias
The Efficacy of Adapted Yoga in Managing Psychosocial Risk in Implantable Cardioverter Defibrillator (ICD) Patients
Psychosocial risks are significant in the management of patients with cardiovascular disease and implantable cardioverter defibrillators (ICD) devices. This is a randomized, controlled, clinical study.
- Trial name
- NCT01716351
- Testing
- Adapted Yoga Intervention for Implantable Cardioverter Defibrillator (ICD) Recipients
- Volunteers
- 55 people
- Sponsor
- Yale University
Dark-adapted ERG
Electroretinography: Investigation of a Protocol Change
The study evaluates whether an eye test called an electroretinogram (ERG) can be shortened and still produce the same diagnostic results.
- Trial name
- SHERG (NCT03275441)
- Testing
- Electroretinography
- Volunteers
- 262 people
- Sponsor
- NHS Greater Glasgow and Clyde
Supraventricular Tachycardia
Using Non-Fluoroscopic Imaging Devices to Decrease Radiation Exposure During Ablation of Supraventricular Tachycardia
The purpose of this study is to determine whether the additional use of non-fluoroscopic imaging modalities can decrease the use of radiation exposure during standard ablation procedures for supraventricular tachycardia (SVT) in…
- Trial name
- NCT00979303
- Testing
- Intracardiac echocardiography and 3D navigational system
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Boston Children's Hospital
Telemedicine, Heart Failure
Electronic Device Implantation Through Remote Guidance
Implantable cardioverter defibrillators (ICD) and cardiac resynchronization therapy defibrillator (CRT-D) implants are limited by availability and costs of field clinical specialist (FCS) bioengineers.
- Conditions
- Telemedicine, Heart Failure, Defibrillators
- Trial name
- NCT06404021
- Testing
- interventional cardiology procedures with proctoring system, interventional cardiology procedures with engineer in the electrophysiology laboratory
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Calabria
Atrial Fibrillation, Ischemic Ventricular Tachycardia
Study of a New Catheter Using Force Sensing Capabilities for the Treatment of Atrial Fibrillation and Ventricular Tachycardia
The purpose of this study is to study the treatment of Atrial Fibrillation and ischemic Ventricular Tachycardia using a RF ablation catheter with contact force sensing capabilities.
- Trial name
- EZCF-125 (NCT01032317)
- Testing
- Radiofrequency Catheter Ablation
- Where
- Czechia
- Volunteers
- 22 people
- Sponsor
- Biosense Webster, Inc.
Sentence Stimulus, Auditory Noise
Effects of Listening Effort on Sentence Processing and Memory (Study 1)
Sensorineural hearing loss (SNHL) is among the most prevalent chronic conditions in aging and has a profoundly negative effect on speech comprehension, leading to increased social isolation, reduced quality of life, and increased…
- Trial name
- NCT05584514
- Testing
- Sentence Stimulus, Auditory Noise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Utah
Brain Ischemia, Hemiplegic Patients With Stroke
Using fMRI and sEMG to Evaluate the Effects and Mechanism on Abdominal Acupuncture Combined With Upper Limb Rehabilitation Training on Brain Plasticity of Hemiplegic Patients With Stroke
Using random number method to categorize the selected first onset patients with stroke who meet the inclusion criteria into 3 groups.The patients were randomly divided into treatment group A(abdominal acupuncture+upper limb…
- Conditions
- Brain Ischemia, Hemiplegic Patients With Stroke, Image Science, Electrophysiology of Neuromuscular
- Trial name
- NCT03712085
- Testing
- Abdominal acupuncture
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 66 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Electrophysiology
Study of the Long-Term Effect of Frequent Anti-VEGF Dosing on Retinal Function in Patients With Neovascular AMD
THis study aims to determine whether frequent dosing of intravitreal injections of Ranibizumab (Lucentis) or Bevacizumab (Avastin), which act as VEGF inhibitors, has a deleterious effect on the retina, studied by…
- Trial name
- NCT00533689
- Testing
- Electroretinography (ERG), Visual Evoked Potentials (VEP)
- Where
- Israel
- Volunteers
- 2,008 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Myofascial Trigger Points
A Clinical Observation on Electrophysiology in Headache Patients With Myofascial Trigger Points
Through an observational, cross-sectional study, muscle activity was compared among 21 subjects with episodic headache, 17 subjects with chronic headache and 17 age-matched healthy controls.
- Trial name
- NCT03890393
- Testing
- Electromyography
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Child Development
Follow up of Long Term Neurodevelopmental Impact of the Type of Feeding During the First Year of Life at 10 Years Old
The Chilean infant Nutrition Trial was a prospective, randomized, double-blind, controlled study conducted in Santiago, Chile, between 2016 and The study aimed to evaluate growth and body composition changes between birth and two…
- Trial name
- NCT06917625
- Testing
- Imaging
- Where
- Chile
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Corporación de Apoyo de la Investigación Científica en Nutrición
Cardiac Arrhythmia
Novel Cardiac Signal Processing System
This study is designed to collect parallel intracardiac signal data during pre-defined periods of clinical interest from the PURE EP system and the existing signal recording and mapping systems.
- Trial name
- NCT04112433
- Testing
- PURE EP 2
- Where
- 3 sites in United States
- Volunteers
- 104 people
- Sponsor
- BioSig Technologies, Inc.
Glioma, Glioblastoma (GBM)
Pilot IntraOperative Neuronal Electrophysiology in Tumor rElatEd suRgery
INTRODUCTION AND RATIONALE Aggressive brain tumors like glioma have the ability to infiltrate the surrounding healthy brain tissue, disrupting normal neuronal activities and leading to impaired motor and cognitive functions, as…
- Conditions
- Glioma, Glioblastoma (GBM), Brain Tumor-Glioma, Brain Metastasis
- Trial name
- PIONEER (NCT06617208)
- Testing
- Neuropixel probe recording
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Erasmus Medical Center
Parkinson Disease
Minimal Electrophysiology and Imaging Enhanced Deep Brain Stimulation
The goal of this study is to learn if Deep Brain Stimulation (DBS) surgery can be streamlined for patients being treated for Parkinson's disease.
- Trial name
- MIXT-DBS (NCT06572150)
- Testing
- Deep Brain Stimulation - Minimal Electrophysiology, Deep Brain Stimulation - Standard
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Parkinson
Electrophysiological Activity of the Subthalamic Nucleus During the Processing of Emotional and Motivational Information
The role of the basal ganglia in the processing of information with emotional or motivational content has been demonstrated by several lesion and functional imaging studies in humans and animals.
- Trial name
- EMOPHYSIO (NCT01537224)
- Testing
- Measure of the electrophysiological activity of the subthalamic nucleus
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Rennes University Hospital
Non Specific Chronic Low Back Pain
Clinical Electrophysiology Assessment for Low Back Pain
Non specific chronic low back pain (LBP) is a debilitating disorder characterized by tremendous personal and socioeconomic impact, with long-term sick leave, low quality of life, and very high financial costs.
- Trial name
- LBP (NCT03511404)
- Testing
- physiotherapy rehabilitation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong