Clinical trials: Elective Abdominal Surgery
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
Surgical Site Infection
Comparison of Two Preoperative Antiseptic Solutions Alcohol Based in Abdominal Elective Surgeries
Pragmatic randomized clinical trial comparing Iodine Povacrylex based on alcohol to Chlorhexidine also based on alcohol in efficacy and security to diminish frequency of surgical site infections in major abdominal elective clean…
- Trial name
- NCT03859908
- Testing
- Iodine Povacrylex 7 MG/ML / Isopropyl Alcohol 0.74 ML/ML, Chlorhexidine Gluconate 20 MG/ML / Isopropyl Alcohol 0.7 ML/ML
- Where
- El Salvador
- Volunteers
- 18 people
- Sponsor
- Universidad de El Salvador
Inguinal Hernia, Acute Appendicitis
The Onset Time of Rocuronium in Emergency and Elective Surgery
Rocuronium, a nondepolarizing neuromuscular blocking agent, is used in general anesthesia to provide conditions for endotracheal intubating.
- Trial name
- NCT02634255
- Testing
- Rocuronium elective surgery, Rocuronium emergency surgery, Propofol
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Visceral Obesity, Colorectal Surgery
Visceral Obesity and Colorectal Surgery
While perirenal fat measurement is an easy reproducible surrogate of visceral fat, its value as independent parameter in predicting postoperative complications after colorectal resection remains poorly investigated.
- Conditions
- Visceral Obesity, Colorectal Surgery, Risk Factor
- Trial name
- NCT01620697
- Testing
- Colorectal surgery
- Where
- Switzerland
- Volunteers
- 224 people
- Sponsor
- University Hospital, Geneva
Abdominal Surgery
Remote Telemonitoring to Improve Prehabilitation and Surgical Outcomes of Patients Undergoing Elective Abdominal Surgery
There is data confirming that simple tests of physical capability, such as the timed "get-up-and-go" test and the 6-minute walk test, correlate with surgical outcomes.
- Trial name
- NCT03706963
- Testing
- Phone Call
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Washington University School of Medicine
Elective Endovascular Abdominal Aortic Surgery With an Expected Surgical Duration Exceeding 2 Hours, Elective Open Abdominal Aortic Surgery With an Expected Surgical Duration Exceeding 2 Hours
The Hypotension Prediction Index Versus Standard Advanced Haemodynamic Monitoring in Patients Undergoing Major Aortic Surgery
The standard procedure during general anesthesia is to monitor vital functions, including cardiovascular functions such as cardiac electrical activity, using continuous ECG recording, blood pressure measurement with a…
- Trial name
- HYPE-AORTA (NCT07510451)
- Testing
- HPI guided heamodynamic monitoring, Standard Heamodynamic Managament according to APCO Monitoring
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Poznan University of Medical Sciences
Anemia, Surgery
Preoperative Monoferric for Abdominal Surgery
Although there are multiple formulations of intravenous (IV) iron to choose from, a one-time dose of Monoferric would make it more feasible to integrate it in the perioperative pathway given an often-limited time between…
- Trial name
- NCT05258825
- Testing
- Monoferric
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Brigham and Women's Hospital
Abdominal Surgery
Impact of NOL Index Intraoperative Guided Remifentanil Analgesia
The Physiological Monitoring Device (PMD-200™) system is comprised of a monitor and a designated finger probe containing 4 sensors.
- Trial name
- Eu-MultiNOL (NCT04402242)
- Testing
- Bispectral index, Bispectral index + NOL index
- Where
- 3 sites in France
- Volunteers
- 90 people
- Sponsor
- Hopital Foch
Patients Ongoing Elective Abdominal Laparoscopy
Laparoscopic Surgery and Abdominal Compliance
The objective of the study is to describe factors influencing abdominal compliance during laparoscopic surgery, including neuromuscular blocking agents (NMBA).
- Trial name
- COELIOCUR (NCT02816567)
- Testing
- propofol, NMBA - cisatracurium, sufentanil
- Where
- France
- Volunteers
- 180 people
- Sponsor
- CHU de Reims
Type 2 Diabetes Mellitus, Elective Abdominal Surgery
Preoperative Carbohydrate Loading in Diabetic Patients Undergoing Elective Abdominal Surgery
This study evaluates the effect of preoperative carbohydrate loading on early postoperative recovery in patients with type 2 diabetes mellitus undergoing elective abdominal surgery.
- Conditions
- Type 2 Diabetes Mellitus, Elective Abdominal Surgery, Gastric Emptying, Postoperative Recovery
- Trial name
- CARB-DM (NCT07451015)
- Testing
- Standard Preoperative Fasting With Water, Preoperative Oral Carbohydrate Loading
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Local Anesthetic Toxicity, Regional Anesthesia Morbidity
Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery
Primary aim: observe the incidence of systemic toxicity from local anesthetic (LAST) after performing fascial blocks in patients undergoing elective cardio-thoracic and abdominal surgery.
- Conditions
- Local Anesthetic Toxicity, Regional Anesthesia Morbidity, Postoperative Pain
- Trial name
- NCT05592691
- Testing
- Fascial block
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Major Abdominal Surgery
Preoperative Measurement of Heart Rate Variability as a Predictor of Postoperative Outcome
The purpose of the study is to confirm the hypothesis that a dysfunction of the autonomic nervous system could complicate the postoperative course in the patient undergoing surgery.
- Trial name
- NCT02375412
- Testing
- Pre-operative measurement of heart rate variability
- Where
- Czechia
- Volunteers
- 65 people
- Sponsor
- University Hospital Ostrava
Wound Infection
Abdominal Wall Closure With Triclosan-coated Suture (TCS09-10)
After open colo-rectal surgery the surgical site infection (SSI) is very high among abdominal surgeries. The goal of the investigators randomized, prospective, multicentric, internet-based study is to compare rate of SSI after…
- Trial name
- NCT01123616
- Testing
- abdominal wall closure
- Where
- Hungary
- Volunteers
- 1 people
- Sponsor
- University of Pecs
Bilateral Inguinal Hernia Repair, Open Upper Abdominal Surgeries
Ultrasound-guided Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Children Undergoing Elective Open Lower Abdominal Surgeries
To compare the postoperative analgesic efficacy of ultrasound-guided Quadratus Lumborum Block (anterior approach) versus Erector Spinae Plane Block (T10-T12 level), both performed bilaterally with 0.25% bupivacaine (0.5 mL/kg per…
- Trial name
- NCT07853586
- Testing
- ultrasound guided anterior oudratus lumborum block, Ultrasound guided erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Inguinal Hernia, Postoperative Pain
Comparison of Lornoxicam and Paracetamol for Pre-emptive Intravenous Analgesia for Elective Inguinal Hernia Repair
The purpose of this study is to determine whether lornoxicam or paracetamol is more effective in providing pre-emptive analgesia for adult patients undergoing elective unilateral inguinal hernia repair under general anesthesia.
- Trial name
- NCT01069055
- Testing
- Sterile Saline, Intravenous lornoxicam, Intravenous paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Pain
A Study of the Recovery Benefits After Treatment With Parecoxib/Valdecoxib in Patients Undergoing Abdominal Surgery
The purpose of this study is to evaluate morphine intake in the first 4 hours after abdominal surgery. Morphine intake is compared between patients on placebo and patients on parecoxib/valdecoxib.
- Trial name
- NCT00651300
- Testing
- Parecoxib/Valdecoxib
- Where
- 8 sites in Australia
- Volunteers
- 91 people
- Sponsor
- Pfizer
Respiratory Mechanics
Ultrasonographic Abdominal Fat Thickness and Driving Pressure During Prone Spinal Surgery
This prospective observational study aims to evaluate the association between preoperative abdominal subcutaneous fat thickness measured by ultrasonography and intraoperative driving pressure in adult patients undergoing elective…
- Trial name
- NCT07723690
- Volunteers
- 120 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Renal Perfusion, Minimally Invasive Surgical Procedures
Assessment of Renal Perfusion Using Ultrasound and Near-Infrared Spectroscopy in Patients Undergoing Minimally Invasive Abdominal Surgery
This prospective observational study aims to evaluate renal perfusion in adult patients undergoing elective minimally invasive abdominal surgery.
- Conditions
- Renal Perfusion, Minimally Invasive Surgical Procedures, Acute Kidney Injury
- Trial name
- RRI-NIRS (NCT07635160)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Acute Kidney Injury, Postoperative Complications
Hypotension Prediction Index-guided Hemodynamic Optimization Trial to Reduce Postoperative Acute Kidney Injury (HYT).
MAIN AIM OF THE STUDY To establish whether hemodynamic management guided by the hypotension prediction index (HPI) guided by the administration of intravenous fluids and vasoactive drugs in patients undergoing elective major…
- Trial name
- HYT (NCT05569265)
- Testing
- Intraoperative hemodynamic management
- Where
- 26 sites in Spain
- Volunteers
- 958 people
- Sponsor
- Maria José Clara Colomina Soler
Laparotomy Closure After Abdominal Surgery, Suture Materials
Comparison of Vicryl Versus Prolene for Midline Rectus Sheath Closure After Elective Laparotomy
This randomized controlled trial compared two commonly used suture materials, Prolene and Vicryl, for closing the midline rectus sheath after elective laparotomy.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Suture Materials, Complications Wounds
- Trial name
- NCT07451990
- Testing
- Vicryl (Polyglactin 910) Suture, Prolene (Polypropylene) Suture
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Hayatabad Medical Complex