Clinical trials: Elective Abdominal Surgery
Major Abdominal Surgery
Preoperative Measurement of Heart Rate Variability as a Predictor of Postoperative Outcome
The purpose of the study is to confirm the hypothesis that a dysfunction of the autonomic nervous system could complicate the postoperative course in the patient undergoing surgery.
- Trial name
- NCT02375412
- Testing
- Pre-operative measurement of heart rate variability
- Where
- Czechia
- Volunteers
- 65 people
- Sponsor
- University Hospital Ostrava
the Effect of Intraoperative Magnesium Infusion on Postoperative Cognitive Functions in Adult Patients After Elective Pelvi-abdominal Surgeries
Effect of Intraoperative Magnesium Infusion on Postoperative Pain and Cognitive Function
The aimof this study is to observe the effect of intraoperative magnesium infusion on peri-operative pain and postoperative cognitive functions in adult patients after elective pelvi-abdominal surgeries.
- Trial name
- NCT04256057
- Testing
- Magnesium Sulfate
- Where
- 3 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Beni-Suef University
Postoperative Morbidity, Postoperative Mortality
Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study)
The primary purpose of the study is to evaluate whether the type of fluid (0.9% saline or 6% Hydroxyethyl starch 130/0.4) in the context of an individualized goal-directed fluid therapy is associated with a difference in…
- Trial name
- FLASH (NCT02502773)
- Testing
- Hydroxethyl starch
- Where
- France
- Volunteers
- 826 people
- Sponsor
- University Hospital, Clermont-Ferrand
Elective Abdominal Surgery
Comparison of the Risk of Surgical Site Infections Between Dressings Stopped at Postoperative Day 1 vs Dressings Stopped at Postoperative Day 6+/-1 After Elective Abdominal Surgery
The daily changing of postoperative dressings is a widespread practice, often continuing until the 5th-7th day after surgery. In theory, dressings aim to reduce the risk of superficial surgical site infections (SSIs).
- Trial name
- PAN-STOP (NCT06569862)
- Testing
- Postoperative day 1 dressing, Postoperative day 6+/-1 dressing
- Where
- France
- Volunteers
- 1,288 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kinesiophobia
Kinesiophobia, Postoperative Pain, and Early Mobilization After Elective Abdominal Surgery
This study examines the level of kinesiophobia (fear of movement) in patients undergoing elective abdominal surgery and its relationship with postoperative pain severity and early mobilization.
- Trial name
- NCT07834554
- Testing
- Tampa Scale for Kinesiophobia (TSK)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Volkan Gokmen
Laparotomy Closure After Abdominal Surgery, Suture Materials
Comparison of Vicryl Versus Prolene for Midline Rectus Sheath Closure After Elective Laparotomy
This randomized controlled trial compared two commonly used suture materials, Prolene and Vicryl, for closing the midline rectus sheath after elective laparotomy.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Suture Materials, Complications Wounds
- Trial name
- NCT07451990
- Testing
- Vicryl (Polyglactin 910) Suture, Prolene (Polypropylene) Suture
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Hayatabad Medical Complex
Major Abdominal Surgery, Duodenohemipancreatectomy
Intraoperative Haemodynamic Optimization Comparing Flow and Pressure Parameters
The purpose of the study is to confirm the hypothesis that flow treatment algorithm based on cardiac index trending by transesophageal Dopplerometry would result in reduced complications and reduced length of hospital stay in…
- Conditions
- Major Abdominal Surgery, Duodenohemipancreatectomy, Rectal Resection, Extensive Bowel Surgery
- Trial name
- Flow-press (NCT02104687)
- Testing
- Flow group, Press group
- Where
- Czechia
- Volunteers
- 140 people
- Sponsor
- University Hospital Ostrava
Anemia, Iron-Deficiency
Efficacy of a Preoperative Anaemia Clinic in Patients Undergoing Elective Abdominal Surgery
Efficacy of a preoperative anaemia clinic in patients undergoing elective abdominal surgery diagnosed with iron deficieny anaemia
- Trial name
- NCT05628896
- Where
- Denmark
- Volunteers
- 764 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Aortic Aneurysm, Abdominal
NExT ERA: National Expertise Based Trial of Elective Repair of Abdominal Aortic Aneurysms: A Pilot Study
Objectives. To study the feasibility of an expertise-based randomized controlled trial (RCT) testing the role of traditional surgery (OPEN) versus endovascular repair (EVAR) for abdominal aortic aneurysms (AAA). Study design.
- Trial name
- NCT00358085
- Testing
- Endovascular Repair of Abdominal Aortic Aneurysm, Conventional open repair of Abdominal Aortic Aneurysm
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Hamilton Health Sciences Corporation
Elective Endovascular Abdominal Aortic Surgery With an Expected Surgical Duration Exceeding 2 Hours, Elective Open Abdominal Aortic Surgery With an Expected Surgical Duration Exceeding 2 Hours
The Hypotension Prediction Index Versus Standard Advanced Haemodynamic Monitoring in Patients Undergoing Major Aortic Surgery
The standard procedure during general anesthesia is to monitor vital functions, including cardiovascular functions such as cardiac electrical activity, using continuous ECG recording, blood pressure measurement with a…
- Trial name
- HYPE-AORTA (NCT07510451)
- Testing
- HPI guided heamodynamic monitoring, Standard Heamodynamic Managament according to APCO Monitoring
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Poznan University of Medical Sciences
Incisional Hernia, Hernia
Comparison of Mesh Fixation Techniques in Elective Laparoscopic Repair of Incisional Hernia - ReliaTack™ v ProTack™
This study is designed to examine the effects on post operative pain after the use of a fixation device to secure a mesh in the abdomen to repair a hernia of the abdominal wall.
- Conditions
- Incisional Hernia, Hernia, Abdominal Hernia
- Trial name
- TACKoMesh (NCT03434301)
- Testing
- ReliaTack™, Protack™
- Where
- United Kingdom
- Volunteers
- 63 people
- Sponsor
- Manchester University NHS Foundation Trust
Infection
Abdominal Wall Closure With Triclosan-coated Suture
After open colorectal surgery the surgical site infection (SSI) is very high among abdominal surgeries. The goal of the investigators randomized, prospective, multicentric, internet-based study is to compare rate of SSI after…
- Trial name
- TCS09 (NCT01620294)
- Testing
- abdominal wall closure, surgical site infection
- Where
- Hungary
- Volunteers
- 1 people
- Sponsor
- University of Pecs
Anemia, Surgery
Preoperative Monoferric for Abdominal Surgery
Although there are multiple formulations of intravenous (IV) iron to choose from, a one-time dose of Monoferric would make it more feasible to integrate it in the perioperative pathway given an often-limited time between…
- Trial name
- NCT05258825
- Testing
- Monoferric
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Brigham and Women's Hospital
Abdominal Surgery
Impact of NOL Index Intraoperative Guided Remifentanil Analgesia
The Physiological Monitoring Device (PMD-200™) system is comprised of a monitor and a designated finger probe containing 4 sensors.
- Trial name
- Eu-MultiNOL (NCT04402242)
- Testing
- Bispectral index, Bispectral index + NOL index
- Where
- 3 sites in France
- Volunteers
- 90 people
- Sponsor
- Hopital Foch
Hypovolaemia Due to Acute Blood Loss
Safety and Efficacy of 6% Hydroxyethyl Starch (HES) Solution Versus an Electrolyte Solution in Patients Undergoing Elective Abdominal Surgery
The aim of the study is to investigate the safety of a 6% HES (Hydroxyethyl Starch) solution (Volulyte 6%) versus an electrolyte solution (Ionolyte) in patients undergoing elective abdominal surgery.
- Trial name
- PHOENICS (NCT03278548)
- Testing
- Volulyte 6%, Ionolyte
- Where
- 61 sites in Austria, Belgium and 8 more
- Volunteers
- 2,289 people
- Sponsor
- Fresenius Kabi
Inguinal Hernia, Postoperative Pain
Comparison of Lornoxicam and Paracetamol for Pre-emptive Intravenous Analgesia for Elective Inguinal Hernia Repair
The purpose of this study is to determine whether lornoxicam or paracetamol is more effective in providing pre-emptive analgesia for adult patients undergoing elective unilateral inguinal hernia repair under general anesthesia.
- Trial name
- NCT01069055
- Testing
- Sterile Saline, Intravenous lornoxicam, Intravenous paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Tissue Adhesions
The Effect of Adhesiolysis During Elective Abdominal Surgery on Per- and Postoperative Complication, Quality of Life and Socioeconomic Costs
Official title: LAPAD - A prospective study on the effect of adhesiolysis during elective laparotomy or laparoscopy on per- and postoperative complication, quality of life and socioeconomic costs Background: With improved…
- Trial name
- LAPAD (NCT01236625)
- Testing
- Adhesiolysis
- Where
- Netherlands
- Volunteers
- 752 people
- Sponsor
- Radboud University Medical Center
Local Anesthetic Toxicity, Regional Anesthesia Morbidity
Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery
Primary aim: observe the incidence of systemic toxicity from local anesthetic (LAST) after performing fascial blocks in patients undergoing elective cardio-thoracic and abdominal surgery.
- Conditions
- Local Anesthetic Toxicity, Regional Anesthesia Morbidity, Postoperative Pain
- Trial name
- NCT05592691
- Testing
- Fascial block
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
This Study Mainly Focus on the Eras Protocol Decreasing Time of Npo and Early Discharge From Hospital to Avoid Hospital Acquired Infections
A Comparative Study of Preoperative Carbohydrate Loading Dose and Fasting on Postoperative Recovery Time in Elective Abdominal Surgery Patients
This randomized controlled trial aims to compare the effect of preoperative carbohydrate loading versus standard overnight fasting on postoperative recovery time in patients undergoing elective abdominal surgery.
- Trial name
- NCT07562776
- Testing
- Patients will be given 400 mL of a carbohydrate-rich clear drink (10% daxtrosewater) approximately 2-3 hours before induction of anesthesia, according to ERAS guidelines., Standard pre operative fasting
- Volunteers
- 144 people
- Sponsor
- Gulab Devi Hospital
Pain
A Study of the Recovery Benefits After Treatment With Parecoxib/Valdecoxib in Patients Undergoing Abdominal Surgery
The purpose of this study is to evaluate morphine intake in the first 4 hours after abdominal surgery. Morphine intake is compared between patients on placebo and patients on parecoxib/valdecoxib.
- Trial name
- NCT00651300
- Testing
- Parecoxib/Valdecoxib
- Where
- 8 sites in Australia
- Volunteers
- 91 people
- Sponsor
- Pfizer