Clinical trials: Elderly Adults
HIV Seropositivity
Telephone Counseling to Enhance the Quality and Safety of Romantic and Sexual Relationships in People Living and Aging With HIV
The purpose of this study is to determine if a brief behavioral intervention delivered over the telephone is effective at reducing occasions of condomless sex in persons living and aging with HIV.
- Trial name
- NCT03004170
- Testing
- Telephone-Administered Motivational Interviewing Plus Behavioral Skills Training, Telephone-Administered Coping Effectiveness Training
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- Oregon Health and Science University
Physical Activities, Elderly
Effectiveness of a Physical Activity Program
study with multicomponent exercise
- Conditions
- Physical Activities, Elderly, Adults
- Trial name
- EPAP (NCT07662551)
- Testing
- Balance exercise, Multicomponent exercises
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Pará
Influenza
Safety, Immunogenicity, and Relative Efficacy of H1N1 Vaccines in Adults Aged 18 Years and Older
The purpose of this study is to characterize the safety, immunogenicity, and relative efficacy of the H1N1 (swine) flu vaccines GSK2340273A and GSK2340274A in adults 18 years of age or older.
- Trial name
- NCT00979602
- Testing
- GSK2340274A, GSK2340273A
- Where
- 38 sites in United States, Canada
- Volunteers
- 4,048 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Frailty, Fall Risk, Fall Prevention
Physical Function and Fall Risk in Older Adults in the Lalín Frailty Prevention Program
This prospective observational study will describe changes in physical function and fall risk among adults aged 70 years or older who participate in the routine Frailty and Falls Prevention Program at the Centro Integral de Saúde…
- Trial name
- FRAIL-Lalin (NCT07848802)
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- University of Vigo
Critically Ill Intensive Care Unit Patients, Physician-Family Communication in Intensive Care Units
The Four Supports Study: Family Support Intervention in Intensive Care Units
The purpose of this study is to test the effectiveness of a multi-faceted communication intervention for family members of critically ill patients to reduce the family members' long-term symptoms of depression and anxiety.
- Conditions
- Critically Ill Intensive Care Unit Patients, Physician-Family Communication in Intensive Care Units, Surrogate Decision-making for Critically Ill Patients
- Trial name
- NCT01982877
- Testing
- Four Supports Intervention, Educational Control Intervention
- Where
- United States
- Volunteers
- 546 people
- Sponsor
- University of Pittsburgh
Accidental Falls
Fall Prevention Program for Older Adults
The purpose of this study is to test the effectiveness of a fall prevention program for older adults. Participants assigned to the intervention group will train weekly on a special treadmill that will simulate tripping.
- Trial name
- NCT00714051
- Testing
- fall prevention training, Attention Control
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- US Department of Veterans Affairs
Cognitive Enhancement, Aging
Training to Enhance Cognition in Older Adults
This is a planning project with a clinical trial pilot to prepare for a larger fully powered clinical trial. Goals of this pilot project are: to identify and address any modifications of the games required for adaptation to…
- Trial name
- NCT03900702
- Testing
- Gaze-driven training games
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jeanne Townsend, PhD
Hearing Loss, Cognitive Impairment
Auditory-Cognitive Optimization Care Program for Older Adults With Hearing Loss and Cognitive Impairment
Hearing loss and cognitive impairment are common and interrelated health problems that may affect communication, information processing, attention, psychological well-being, daily functioning, and quality of life.
- Trial name
- A-COP (NCT07869745)
- Testing
- Auditory-Cognitive Optimization Care Program (A-COP), Hearing Management and Newspaper-Reading Activities
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Taipei Medical University
Aging
Age-independent Decline in Manual Dexterity of Middle-aged and Older Adults
The objective of the clinical trial is to evaluate the mediating influence of force control on the pegboard times of adults (50-89 years) who are stratified into groups of faster and slower pegboard times.
- Trial name
- NCT03803566
- Testing
- Pegboard practice, Force control practice
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Sleep
A Personalized Behavioral Intervention to Improve Physical Activity, Sleep and Cognition in Sedentary Older Adults
Cognitive decline and sleep complaints are prevalent in older adults and severely affect older adults' physical health and quality of life.
- Trial name
- NCT03959202
- Testing
- ELDERFITNESS, Control
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Phase I Study of MLN 9708 in Addition to Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia in Older Adults
This research study is evaluating a combination of drugs considered standard treatment for children and young adults with acute lymphoblastic leukemia (ALL), in combination with a new drug called MLN 9708.
- Conditions
- Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, B-cell Adult Acute Lymphoblastic Leukemia, T-cell Adult Acute Lymphoblastic Leukemia
- Trial name
- NCT02228772
- Testing
- MLN 9708, Vincristine, Cytarabine
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts General Hospital
Overweight, Obesity and Other Hyperalimentation
Nutritional and Physical Activities for Overweight and Obese Older Adults
This cluster randomized trial aims to test nutritional and physical activity interventions in older adults in nursing homes. The overall research question are: o What are the effects of nutritional and physical activity…
- Trial name
- IFEBO (NCT05804019)
- Testing
- Nutritional and physical interventions
- Where
- 6 sites in Denmark
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University College Absalon
Discharge Planning, Emergency Medicine
Use of a Brief Phone Call After ED Discharge
The purpose of this study is to determine whether a phone call from a nurse within 1-3 days after discharge from the Emergency Department (ED) decreases return visits to the ED/ hospital admissions/ death (combined outcome) in…
- Conditions
- Discharge Planning, Emergency Medicine, Geriatrics, Patient Readmission
- Trial name
- NCT01893931
- Testing
- ED Discharge & Medication Call
- Where
- United States
- Volunteers
- 2,003 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Respiratory Infection
Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory Infection
This study will evaluate whether an expanded diagnostic strategy can reduce antibiotic use in patients aged 65 years or older who are hospitalized with community-acquired acute respiratory infection, without negatively affecting…
- Trial name
- NeuBluMul (NCT07883902)
- Testing
- Expanded Diagnostic Strategy, Conventional Diagnostic Strategy
- Where
- Spain
- Volunteers
- 406 people
- Sponsor
- Santiago Lopez Gil
Postural Balance, Aging
Immediate Effects of Vojta Therapy on Postural Control in Older Adults
This exploratory randomized assessor-blinded study aimed to determine whether a single session of Reflex Locomotion Therapy according to Vojta produces immediate changes in postural control in community-dwelling older adults…
- Conditions
- Postural Balance, Aging, Frailty
- Trial name
- VOJTABALANCE (NCT07829172)
- Testing
- Reflex Locomotion Therapy according to Vojta, Educational Session
- Where
- Chile
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Marianela Alejandra Valenzuela Sandoval
Healthy Aging
The Effects of Different Intensity Training on Dynamic and Static Balance of Elderly
In this study, investigators tried to find a useful and safe way of training for the elderly population which can help this population to improve their fitness factors as fast as possible.
- Trial name
- NCT04901520
- Testing
- High Intensity Training, Moderate Intensity Training, Low Intensity Training
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Fall, Balance
Effect of Single-task, Dual-task and Analogy Training During Gait Rehabilitation
The study aims to examine the effect of single-task, dual-task and analogy training during gait rehabilitation on conscious motor processing propensity, balance, walking ability and fear of falling by older adults at risk of…
- Conditions
- Fall, Balance, Reinvestment Propensity, Gait Rehabilitation
- Trial name
- NCT03811782
- Testing
- Single-task Training, Dual-task Training, Analogy Training
- Where
- Hong Kong
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Critical Illness
Multi-component Family Support Tool Intervention (FST)
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually or survive…
- Trial name
- FST (NCT05019261)
- Testing
- Multi-component Family Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sarcopenia
Vitamin D and Physical Activity for Prevention of Sarcopenia in Osteoporosis
In the present study the aim was to determine the prevalence of sarcopenia and to evaluate the effectiveness of an exercise program and vitamin D supplementation in enhancing muscle mass and strength in community-dwelling older…
- Trial name
- NCT01666522
- Testing
- Vitamin D, Physical activity
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- University of Alexandria
Aging, Undernutrition
Determination of In-vivo Plasma AA Appearance From Plant Protein Fibre Products
This study aims to assess the digestibility and efficacy of the study groups previously developed innovative plant-based protein and fibre products.
- Conditions
- Aging, Undernutrition, Appetite Loss, Age-Related Sarcopenia
- Trial name
- NCT05420142
- Testing
- Net peripheral AA appearance following ingestion of 3 selected PPF products compared to whey
- Where
- 2 sites in Ireland, Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University College Dublin
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