Clinical trials: Ejaculatory Dysfunction
Premature Ejaculation
Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation
This study is designed to evaluate the efficacy and safety of DA-8031 and to decide the optimal dose of DA-8031 in male patients with premature ejaculation after oral administration on-demand.
- Trial name
- NCT01798667
- Testing
- DA-8031
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
Healthy
Drug-Drug Interaction of Clomipramine HCl and Sildenafil Citrate in Healthy Males
The purpose of this study is to evaluate the safety and pharmacokinetics/pharmacodynamics of co-administration of Clomipramine HCl 15mg and Sildenafil citrate 100mg compared to the effects after single oral administration in…
- Trial name
- NCT02028598
- Testing
- Treatment 1, Treatment 2, Treatment 3
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CTC Bio, Inc.
Erectile Dysfunction, Premature Ejaculation
A Study to Evaluate Efficacy of Investigational Product HeezOn Ultra -1/ HeezOn Ultra-2 on Male Sexual Health
Sexual function is a part of a normal healthy life and considered to be essential for mental, physical and marital well-being. Any derangement in normal function though is a distressing situation for the individual, is often not…
- Trial name
- HeezOn-Ultra (NCT02794454)
- Testing
- HeezOn Ultra-1, HeezOn Ultra-2
- Volunteers
- 15 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Premature Ejaculation
Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial
This is a controlled study of patients with and without primary premature ejaculation. It is based on near-infrared spectroscopy (NIRS) functional brain imaging to detect and compare changes in brain activity in resting and task…
- Trial name
- NCT06570135
- Testing
- Detecting Brain Activity with Functional Near Infrared Spectroscopy
- Where
- 2 sites in China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Premature Ejaculation
Safety and Efficacy of Escitalopram in the Treatment of Premature Ejaculation
Escitalopram has been claimed to have the highest selectivity for the human serotonin transporter relative to the noradrenaline or dopamine transporters. This might be associated with greater clinical efficacy.
- Trial name
- NCT00656552
- Testing
- Escitalopram
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Premature Ejaculation, Erectile Dysfunction
The Efficacy and Safety of Dapoxetine/Sildenafil Combination Therapy
The purpose of this study is to evaluate the efficacy and safety of Dapoxetine/Sildenafil 30/50 mg film-coated tablet in the treatment of men with premature ejaculation and erectile dysfunction.
- Trial name
- DAP-SPEED (NCT02939495)
- Testing
- Dapoxetine/Sildenafil 30/50 mg film coated tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
Erectile Dysfunction, Urinary Incontinence
Male Pelvic Floor Muscle Rehabilitation Exercises
Phase I G128 Study Objective The ischiocavernosus (IC) and bulbospongiosus (BS) muscles are vital components of the superficial perineal layer, serving as the foundation for male sexual health and performance.
- Conditions
- Erectile Dysfunction, Urinary Incontinence, Premature Ejaculation
- Trial name
- NCT07451808
- Testing
- Male Pelvic Floor Rehabilitation #1
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dream Video LLC
Premature Ejaculation
A New Treatment for Premature Ejaculation?
The aim of study is to determine if they can produce increases in the IELT using a masturbator in subjects with premature ejaculation, producing improvements in the quality and satisfaction of the sexuality of the patient.
- Trial name
- NCT02297152
- Testing
- FLIP HOLE
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Instituto Sexológico Murciano
Diabetes Mellitus
Retrograde Ejaculation and Sexual Dysfunction in Men With Diabetes Mellitus
Diabetic men and controls are examined for retrograde ejaculation, and erectile dysfunction is registered with a validated questionaire (International Index of Erectile Function-15).
- Trial name
- NCT01743599
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Odense University Hospital
Premature Ejaculation, Lifelong Premature Ejaculation
Pelvic Floor Therapies for Lifelong Premature Ejaculation
This randomized controlled trial will compare three pelvic floor-based treatment modalities in men with lifelong premature ejaculation: electromagnetic pelvic floor stimulation, biofeedback-assisted pelvic floor muscle training…
- Conditions
- Premature Ejaculation, Lifelong Premature Ejaculation, Male Sexual Dysfunction
- Trial name
- PE-PFMT (NCT07627438)
- Testing
- Electromagnetic Pelvic Floor Stimulation, Biofeedback-Assisted Pelvic Floor Muscle Training, Conventional Pelvic Floor Muscle Training
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Sexual Dysfunction, Ejaculation
A Study of Withdrawal Effects With Dapoxetine in the Treatment of Premature Ejaculation
The primary purpose of the study is to assess the possible withdrawal effects after abruptly stopping daily therapy with dapoxetine compared with continuing daily therapy in men with premature ejaculation (PE).
- Trial name
- NCT00210613
- Testing
- Dapoxetine
- Volunteers
- 199 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Premature Ejaculation
A Study To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Two Oral Doses of GSK557296 in a Study in Men With Premature Ejaculation
To determine if an on demand dosing of 50 mg or 150 mg of GSK557296 demonstrates superior efficacy with respect to duration of intra vaginal ejaculatory latency time (IELT) during an 8 week study period compared to placebo in men…
- Trial name
- NCT01021553
- Testing
- GSK557296
- Where
- 8 sites in United States, Netherlands
- Volunteers
- 77 people
- Sponsor
- GlaxoSmithKline
Male Sexual Dysfunction, Ejaculatory Dysfunction
Emsella Chair vs Sham for Male Sexual Dysfunction
We will be performing this study in 2 phases: Phase 1 will be an open label pilot study of 10 male participants. All participants in the pilot study will receive active treatment.
- Trial name
- Emsella_EJD (NCT05370651)
- Testing
- BTL Emsella Chair
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Corewell Health East
Spinal Cord Diseases, Disorder of Ejaculation
Pilot Study of Ejaculatory Dyssynergia by Electronic Microsensors of Sphincters
The objective of this research is to study the sphincter activity during ejaculation in patients with spinal cord injury in order to detect an ejaculatory dyssynergia.
- Trial name
- EDGE (NCT02974673)
- Testing
- Ejaculatory test
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- Lille Catholic University
Premature Ejaculation
Phase 2 Trial of PED-1 and PED-2 in Male Patients With Premature Ejaculation
The purpose of this study is to evaluate whether PED-1 (15mg) and PED-2 (30mg) are tolerable and effective in the treatment of premature ejaculation.
- Trial name
- NCT01203202
- Testing
- Clomipramine
- Where
- 2 sites in South Korea
- Volunteers
- 104 people
- Sponsor
- Symyoo
Erectile Dysfunction, Premature Ejaculation
Efficacy and Safety of Toronto Association in the Treatment of Erectile Dysfunction and Premature Ejaculation
The purpose of this study is to evaluate the efficacy and safety of Toronto association in the treatment of both sexual dysfunction: erectile dysfunction and premature ejaculation.
- Trial name
- NCT05052879
- Testing
- Toronto association, Tadalafil
- Volunteers
- 232 people
- Sponsor
- EMS
Erectile Dysfunction, Coronary Artery Disease
Erectile and Ejaculatory Function Following Coronary Revascularization
This observational, cross-sectional study aims to compare erectile and ejaculatory function between men with a history of coronary revascularization and men without known coronary artery disease.
- Conditions
- Erectile Dysfunction, Coronary Artery Disease, Ejaculation Disorders
- Trial name
- NCT07878260
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Premature Ejaculation
Hyaluronic Acid vs Botulinum Toxin Injection in Treatment of Lifelong Drug-Resistant Premature Ejaculation: Randomized Study
Premature ejaculation (PE) is one of the most common male sexual dysfunctions, often resistant to conventional pharmacological and behavioral treatments.
- Trial name
- NCT07236632
- Testing
- Botulinum toxin type A, Hyaluronic acid
- Volunteers
- 80 people
- Sponsor
- Benha University
Erectile Dysfunction, Sexual Dysfunction
Erectile Dysfunction, Psychological Disorders, and Sexual Performance Among Men Seeking Medical Help for Fertility
According to the World Health Organization (WHO) and the World Association for Sexual Health (WAS), sexual health is directly related to everyone's mental health and quality of life.
- Conditions
- Erectile Dysfunction, Sexual Dysfunction, Premature Ejaculation, Infertile Men
- Trial name
- NCT04941690
- Testing
- A questionnaire method was used.
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The First Hospital of Jilin University
Erectile Dysfunction
A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation
The primary purpose of the study is to demonstrate that dapoxetine can prolong intravaginal ejaculatory latency time (IELT) compared with placebo in men with premature ejaculation (PE).
- Trial name
- NCT00210704
- Testing
- Dapoxetine
- Volunteers
- 1,067 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.