Clinical trials: Efficacy
Esophageal Squamous Cell Carcinoma, Efficacy
Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma
This is an open-label, randomized, controlled phase II study evaluating induction immuno-chemotherapy and concurrent chemoradiotherapy with or without apatinib in unresectable, locally advanced esophageal squamous cell carcinoma
- Conditions
- Esophageal Squamous Cell Carcinoma, Efficacy, Toxicity
- Trial name
- NCT06281886
- Testing
- Induction Immunotherapy-Toripalimab, Induction Chemotherapy-Albumin-paclitaxel combined with cisplatin, Radiotherapy
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Sun Yat-sen University
Efficacy and Safety of Short-course Radiotherapy in Total Neoadjuvant Therapy Combined With Enlonstobart for pMMR Locally Advanced Rectal Cancer
Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC
Efficacy and safety of short-course radiotherapy in total neoadjuvant therapy combined with enlonstobart for pMMR locally advanced rectal cancer
- Trial name
- NCT07448077
- Testing
- Experimental: short-course radiotherapy and immunotherapy, Chemoradiotherapy
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Hebei Medical University Fourth Hospital
Anesthetic Efficacy
Comparison of Anesthetic Efficacy OF 2% Lidocaine Inferior Alveolar Nerve (IANB) Block Versus Primary Buccal Infilteration With 4% Articaine in Symptomatic Irreversible Pulpitis(SIP) IN Mandibular First Molars
This randomized controlled trial aims to compare the anesthetic efficacy of 2% lignocaine administered through an inferior alveolar nerve block (IANB) in one group of participants with 4% articaine delivered via primary buccal…
- Trial name
- IANB SIP EPT (NCT07409896)
- Testing
- INTERVENTION 1: 2% Lignocaine 1:80,000 epinephrine, INTERVENTION 2 : 4%Articaine 1:100,000 epinephrine
- Where
- Pakistan
- Volunteers
- 330 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Assessment of Physical Examination Skills for the Cardiovascular System, Determining Levels of Academic Self-Efficacy
Examining the Effects of ARCS-Based Education on Cardiovascular System Physical Examination Skills, Motivation, and Self-Efficacy Levels in Nursing Students
Objective: The purpose of this study is to determine the effect of ARCS-based nursing education on skill levels, motivation, and self-efficacy in the physical examination of the cardiovascular system.
- Conditions
- Assessment of Physical Examination Skills for the Cardiovascular System, Determining Levels of Academic Self-Efficacy, Determining Motivation Levels, Evaluation of the Effectiveness of the ARCS Intervention
- Trial name
- NCT07733479
- Testing
- ARCS Model Education, Structured Supplementary Training Based on the ARCS Motivation Model
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Analgesic Efficacy
Suzetrigine Frame Trial Comparing Suzetrigine and Acetaminophen
Local anesthetic infiltration is a primary source of acute pain during stereotactic procedures.
- Trial name
- NCT07525219
- Testing
- Suzetrigine, acetaminophen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Burnout, Professional, Occupational Stress
Factors Affecting Burnout in Physiotherapists in Turkey
This cross-sectional descriptive study aims to identify the demographic, occupational, organisational and individual psychological factors that predict burnout among physiotherapists working in active clinical practice in Turkey.
- Conditions
- Burnout, Professional, Occupational Stress, Psychological Resilience, Self Efficacy
- Trial name
- PT-BURNOUT-TR (NCT07722858)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Safety, Efficacy
Tamsulosin Monotherapy Versus Combination Therapy With Tadalafil (2.5 mg vs 5 mg) in Managing Male LUTS Secondary to BPH
This study aims to evaluate the short-term impact and clinical outcomes of tamsulosin monotherapy versus combination therapy with tamsulosin plus tadalafil (2.5 mg vs.
- Conditions
- Safety, Efficacy, Tamsulosin, Monotherapy
- Trial name
- NCT07722884
- Testing
- Tamsulosin 0.4 mg + Tadalafil 2.5 mg, Tamsulosin 0.4 mg + Tadalafil 5 mg, Tamsulosin 0.4 mg
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Menstrual Health Intervention, Product Use Issue
An MHH Intervention in Bangladesh Health Systems
Over 50% of Bangladeshi women and girls use old cloths as menstrual absorbents due to cost, comfort, and familiarity. A substantial proportion, comprising 52% of adolescent girls and 62% of women washed the cloths with soap and…
- Conditions
- Menstrual Health Intervention, Product Use Issue, Hygiene Practices and Knowledge, Menstrual Hygiene Management
- Trial name
- NCT07723885
- Testing
- Menstrual health and hygiene intervention
- Where
- Bangladesh
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Suicide Prevention, Suicide Threat
Psychoeducational Course for Suicide Prevention
The plan is to include patients with a history of increased risk of suicide. In the aftermath of an episode of imminent suicide risk, patients will receive a psychoeducational course that entails information on different aspects…
- Conditions
- Suicide Prevention, Suicide Threat, Self Efficacy, Stress, Psychological
- Trial name
- NCT06466356
- Testing
- Psychoeducational Course for Suicide Prevention, Individual therapy session, Treatment as usual
- Where
- 2 sites in Norway
- Volunteers
- 80 people
- Sponsor
- St. Olavs Hospital
Supplementation Efficacy in Health Adults on Plasticizer Removal
Evaluation of an Oat Fiber Supplement on Health
The purpose of the study is to determine whether short-term use of an oat fiber supplement reduces exposure to your urine levels of dietary chemicals like bisphenol A (BPA).
- Trial name
- NCT07714135
- Testing
- Oat Fiber
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Efficacy, Self, Fatigue; Muscle, Heart
Neuromodulation of the Autonomic Nervous System in Athletes
There are few studies in the literature that have evaluated the effects of using percutaneous stimulation of the auricular branch of the vagus nerve for sports purposes (to accelerate recovery after physical exertion).
- Conditions
- Efficacy, Self, Fatigue; Muscle, Heart, Fatigue, Mental, Fatigue; Combat
- Trial name
- NANSA (NCT06281795)
- Testing
- tVNS
- Where
- Russia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Tracheostomized Patients, Decanulation
Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients
The goal of this study (exploratory sequential design; mixed-methods study) is to evaluate whether a PERMA-H model mobile-based rehabilitation support program delivered to post-tracheostomy oral cancer patients can improve…
- Conditions
- Tracheostomized Patients, Decanulation, Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Rehabilitation Outcome
- Trial name
- NCT07714967
- Testing
- PERMA-H model mobile-based rehabilitation support program
- Where
- 2 sites in China, Malaysia
- Volunteers
- 100 people
- Sponsor
- Hainan Medical College
HbA1c, Self-Efficacy
IMPACT OF DIABETES HEALTHCARE PROGRAM ON GLYCEMIC CONTROL, SELF-EFFICACY AND DIABETES KNOWLEDGE AMONG TYPE-II DIABETICS IN ISLAMABAD PAKISTAN
Type-II Diabetes Mellitus is a significant public health challenge in Pakistan, characterized by a growing prevalence and substantial economic burden.
- Conditions
- HbA1c, Self-Efficacy, Diabetes Knowledge
- Trial name
- NCT06719076
- Testing
- Diabetes Healthcare Program (DHCP)
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Health Services Academy, Islamabad, Pakistan
Caregivers, Community Health Workers
Intervention to Help Orient Men to Excel (IN-HOME) Phase II Study
The goal of the study is to examine the effect of outreach from IN-HOME-trained CHWs on changes in male informal caregiver knowledge/skills, positive attitudes, self-efficacy, and intentions about caregiving topics.
- Conditions
- Caregivers, Community Health Workers, Knowledge, Attitude
- Trial name
- IN-HOME (NCT07704060)
- Testing
- Intervention to Help Orient Men to Excel (IN-HOME), Supplying Useful Perimenopause Through Post-menopause Online Resources and Tools (SUPPORT)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- KDH Research & Communication
Health Behavior, Health Literacy
Social Cognitive Theory-Based Education for Improving Health Outcomes in Older Adults
This study aims to evaluate the effectiveness of a Social Cognitive Theory-based education program on self-efficacy, healthy lifestyle behaviors, and health literacy in older adults aged 65 years and over attending primary care…
- Conditions
- Health Behavior, Health Literacy, Self Efficacy, Aging
- Trial name
- SCT-OLD (NCT07566143)
- Testing
- Social Cognitive Theory-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Muhammet Faruk Yigit
Nursing Education, Medication Administration
Effect of a Chatbot on Nursing Students' Self-Efficacy in Pediatric Medication Administration
This study looked at whether a chatbot can help nursing students feel more confident about giving medicines to children. Giving medicines to children is difficult because doses depend on the child's weight, and mistakes can be…
- Conditions
- Nursing Education, Medication Administration, Self-Efficacy, Patient Safety
- Trial name
- CHATPED (NCT07700290)
- Testing
- Chatbot-supported training
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Tugba KARAKUS TURKER
Yoga, Yoga Exercises
Yoga Asana Chandra Harmoni on Psychological Well-being and Learning Readiness Among Medical Students
The goal of this trial is to learn if the Yoga Asana Chandra Harmoni intervention can improve psychological well-being and learning readiness in medical students.
- Conditions
- Yoga, Yoga Exercises, Well Being, Self Efficacy
- Trial name
- NCT07171268
- Testing
- Yoga Asana Chandra Harmoni
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Breastfeeding Self-efficacy, Maternal Attachment
The Effect Of Postpartum Therapeutıc Touch On Breastfeedıng Self-Effıcacy, Maternal Attachment, And Postpartum Depressıon In Prımıparous Women: A Randomızed Controlled Study
The postpartum period, also known as the fourth trimester, begins with the birth of the baby and lasts approximately 6-8 weeks, varying from person to person.
- Trial name
- NCT07693010
- Testing
- therapeutic touch, terapötik dokunma
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Falls, Fall Injury
Electronic Strategies for Tailored Exercise to Prevent FallS
The objectives of this proposal are to evaluate the eSTEPS CDS (eSTEPS) in a cluster randomized controlled trial. The intervention includes the following: 1) A machine learning-based fall injury risk screening algorithm to…
- Conditions
- Falls, Fall Injury, Exercise Self-Efficacy, Falls Self-Efficacy
- Trial name
- eSTEPS (NCT04993781)
- Testing
- eSTEPS CDS
- Where
- United States
- Volunteers
- 11,945 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Type 1 Diabetes (Juvenile Onset), Type 1 Diabetes
Effect of a Structured Educational Intervention Through Mobile App on Hemoglobin A1c (HbA1c), Self-Efficacy and Self- Care in Adolescent With Type 1 Diabetes (T1DM)
This study aims to evaluate the effectiveness of a mobile health (mHealth) educational intervention for adolescents with Type 1 Diabetes Mellitus (T1DM).
- Conditions
- Type 1 Diabetes (Juvenile Onset), Type 1 Diabetes, Type 1 Diabetes Mellitus, HbA1c
- Trial name
- (T1DM) (NCT07689318)
- Testing
- educational intervention via mobile app
- Volunteers
- 84 people
- Sponsor
- Shifa Tameer-e-Millat University