Clinical trials: Effect of Sleep Deprivation
Epilepsy
The Effect of Sleep Hygiene Given to Epilepsy Patients on Seizure Frequency and Sleep Quality
Epilepsy is a disease that can be seen in everyone, including neurological, chronic, elderly and children. An estimated 50 million people in the world have epilepsy, patients have a history of two or more seizures, the exact…
- Trial name
- NCT06352476
- Testing
- Sleep Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marmara University
Alcohol Intake, Sleep Deprivation
Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.
Although the effects of acute alcohol intake and sleep deprivation on exercise performance lacks evidence in the literature, in many situations, they occur simultaneously.
- Trial name
- NCT02117193
- Testing
- Alcohol intake, Sleep deprivation
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Effect of Sleep Deprivation
Laparoscopic Skills and Cognitive Function Are Not Affected by Night Shifts in Surgeons
The aim of the study was to asses the effect of sleep deprivation during nightshift by monitoring 30 surgeons in unit of surgical gastroenterology in 4 consecutive days.
- Trial name
- NCT01623674
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Sleep Deprivation
The Neurocognitive Effects of Total and Partial Sleep Deprivation in Younger Adults.
This study aims to examine how total and partial sleep deprivation affect brain function, cognitive performance, and biomarkers related to stress and inflammation in the same participants using a crossover design.
- Trial name
- NCT07822009
- Testing
- Total sleep deprivation, Partial sleep deprivation, Normal sleep
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Sleep Deprivation, Hypoxia
Effect of Acute Sleep Restriction on Responses to Hypoxia
At altitude, humans are exposed to environmental hypoxia induced by the decrease in barometric pressure. On duty or in training, mountain troops, paratroopers or aircrew are regularly exposed to altitude.
- Trial name
- HypSom (NCT05563688)
- Testing
- Hypoxia exposure, Sleep deprivation, Cognitive tasks
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Sleep Deprivation
Effect of Work Load and Sleep Deprivation on Medical Staff's Driving Skills
Long and unorthodox working hours (e.g. 24 hours or 23pm-07am shifts for doctors and nurses respectively) combined with sleep deprivation, may affect cognitive functions such as response time and concentration.
- Trial name
- NCT00849706
- Testing
- Study participants will work their regular shifts, and tested after night shifts.No shifts will be added because of the study.
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Sleep Deprivation, Sleep
Effects of Napping in Sleep-Restricted Adolescents
To examine the neurobehavioural responses to two successive cycles of sleep restriction and recovery in adolescents, and to determine the benefits of napping on cognitive performance, alertness, and mood.
- Trial name
- NCT02838095
- Testing
- Nap
- Where
- Singapore
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Sleep Quality
Examining the Differential Effects of Traditional Float-REST and Dry Float on Subjective and Objective Health Outcomes
The objective of this research study is to assess how the implementation of various modern strategies for augmented recovery affect sleep quality, subjective wellness and other indices of general well-being.
- Trial name
- NCT04628910
- Testing
- Simulated Flotation Therapy, Traditional Float-REST Therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Major Depressive Disorder, Bipolar Disorder
The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients
This study evaluates the efficacy of sleep deprivation treatment in accelerating antidepressant responses when administered during the first week of medications and augmenting a sustained response with chronobiological…
- Trial name
- NCT00581009
- Testing
- chronobiological augmentation, sertraline, lithium, one night of sleep deprivation and two FDG PET scans
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Sleep Deprivation, Military Activity
Can Ammonium Inhalants Maintain Performance in Sleep Deprived Soldiers?
This study aims to examine the effectiveness of ammonia inhalants in countering the effects of total sleep deprivation on cognitive and physical performance tests relevant to military personnel.
- Conditions
- Sleep Deprivation, Military Activity, Sleep, Cognitive Change
- Trial name
- NCT05868798
- Testing
- Ammonia Inhalant
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jan Malecek
Sleep Disorder, Sleep, Inadequate
Measuring Sleep Quality In Patients That Posterior Spinal Instrumentatıon Plannıng
Postoperative sleep disorders have serious problems with cognition, pain perception, sustained circadian rhythm, psychomotor function, metabolic function, catabolic responses, and continuity.
- Conditions
- Sleep Disorder, Sleep, Inadequate, Total ıntravenous Anesthesia, Inhalation Anesthesia
- Trial name
- NCT06269328
- Testing
- Total ıntravenous anesthesia with propofol and remifentanil for anesthetic maintenance, Inhalation anesthesia with sevoflurane for anesthetic maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Uludag University
Healthy, Cognition
Reliability of Standardized IQ Testing Under Modafinil, Racetam-Class Compounds, Sleep Restriction and Daily Activity
This study examined whether standardized IQ test scores in healthy adults aged 18-35 are stable measures of cognitive ability and evaluated whether standardized cognitive-test performance and response-initiation measures vary…
- Conditions
- Healthy, Cognition, Sleep Deprivation
- Trial name
- NCT07852130
- Testing
- Modafinil, Oxiracetam, Pramiracetam
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abdulraheem Mohamed Gouda
Sleep Deprivation
Quantifying and Developing Countermeasures for the Effect of Fatigue-Related Stressors on Automation Use and Trust During Robotic Supervisory Control
This project proposes to both develop and test adaptive automation countermeasures for the effects of stressors such as sleep deprivation (SD) on human performance related to robotic tasks, and investigate the relationship…
- Trial name
- NCT02755493
- Testing
- Sleep deprivation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy Volunteers
Sleep Deprivation : Effects on Driving Performance and Central Fatigue
The effects of sleep deprivation (SD) on performance, while contradictory at first glance, are in reality rather clear when exercise duration is considered, i.e. intense/supramaximal versus prolonged exercises.
- Trial name
- PrivSom (NCT01606020)
- Testing
- sleep deprivation, No intervention
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sleep Deprivation, Healthy Volunteers
Effects of Sleep Deprivation on Diaphragm Command During an Inspiratory Endurance Trial in Healthy Volunteers.
The purpose of this study is to assess the impact of sleep deprivation on subjective inspiratory endurance in healthy subjects.
- Conditions
- Sleep Deprivation, Healthy Volunteers, Diaphragm
- Trial name
- NoSleepDiaph (NCT02725190)
- Testing
- Sleepless night, Normal sleep night
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Sleep Deprivation
Protective Effects of Exercise Training
Rationale. Sleep loss is a risk factor for cardiovascular events mediated through endothelial dysfunction. Objective. To determine if 7 weeks of exercise training can limit cardiovascular dysfunction induced by total sleep…
- Trial name
- SOMEX (NCT02820649)
- Testing
- Sleep deprivation
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Sleep
Stable Sleep Pattern Before Sleep Loss
Sleep is now recognized as important for disease prevention. Too little or too much sleep contributes to cardiovascular disease. Leading health organizations recommend adults sleep 7-9 hours per night for optimal health.
- Trial name
- NCT06201390
- Testing
- Sleep consistency
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Alzheimer Disease
Effects of Sleep Deprivation on Cerebrospinal Fluid (CSF) Amyloid-beta (Aβ) Dynamics
Introduction: Alzheimer's disease (AD) is characterized by neurodegeneration of the brain in the form of neurofibrillary tangles and plaques containing the amyloid-beta protein (Abeta).
- Trial name
- AWAKE (NCT01194713)
- Testing
- Sleep deprivation
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Medical Center Nijmegen
Sleep Deprivation
The Effect of Partial and Complete Sleep Deprivation on Heat Tolerance
The purpose of the present study is to evaluate the effect of partial and complete sleep deprivation on exercise heat tolerance. Twelve healthy young male volunteers will participate in the study.
- Trial name
- NCT01596543
- Testing
- partial and complete sleep deprivation
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Histamine, Cowhage
Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep deprivation on itch: To investigate similarity and differences between itch and pain by comparing the effect of sleep…
- Conditions
- Histamine, Cowhage, Sleep Deprivation
- Trial name
- NCT06081998
- Testing
- Histamine, Cowhage
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University