Clinical trials: Edema Arm
Healthy Subject
Effect of Pneumatic Tourniquet on Arm Swelling After Lymph Node Removal
The purpose of the proposed study is to evaluate the acute impact of swelling caused by low-pressure tourniquet use in the setting of ipsilateral prior axillary lymph node dissection and the change in swelling reduction following…
- Trial name
- NCT03584100
- Testing
- Tourniquet 8000
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Stanford University
Branch Retinal Vein Occlusion With Macular Edema
Bevacizumab Versus DEX Implant Followed by Bevacizumab in ME Secondary to BRVO
To evaluate the efficacy of sequential therapy with intravitreal dexamethasone implant followed by bevacizumab compared with bevacizumab monotherapy for macular edema (ME) secondary to retinal vein occlusion (RVO).
- Trial name
- NCT03892434
- Testing
- Intravitreal bevacizumab and dexamethasone implant Injection, Intravitreal dexamethasone implant
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yeungnam University College of Medicine
Distal Radius Fracture
Complex Decongestive Therapy on Distal Radius Fracture
Trauma results in inflammatory reactions accompanied by high protein edema. Trauma can also reduce the carrying capacity of the lymphatic system below normal lymphatic load, leading to exposure of lymphedema.
- Trial name
- NCT04484584
- Testing
- complex decongestive therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Distal Radius Fractures, Instrument-assisted Soft Tissue Mobilization
Effectiveness of Instrument-Assısted Soft Tissue Mobılızatıon in Patients With Operated Distal Radius Fracture
Distal radius fractures are the most common fractures when looking at upper extremity fractures . The incidence of distal radius fractures is increasing day by day, and when looking at the databases of various countries, the…
- Trial name
- NCT06194604
- Testing
- Instrument-assisted soft tissue mobilization, Routine rehabilitation programe
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Proliferative Diabetic Retinopathy (PDR)
High Dose Eylea for Proliferative Diabetic Retinopathy Outcomes
The purpose of this Phase 4 study is to evaluate the safety of aflibercept 8mg in patients with proliferative diabetic retinopathy without center-involved diabetic macular edema.
- Trial name
- HERO (NCT07118670)
- Testing
- Aflibercept 8mg
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Edward Wood, MD
Diabetic Macular Edema
To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema
The purpose of this study was to evaluate the efficacy and safety of brolucizumab in treatment of Chinese patients with visual impairment due to Diabetic Macular Edema.
- Trial name
- KINGLET (NCT04058067)
- Testing
- Brolucizumab, Aflibercept
- Where
- 24 sites in China
- Volunteers
- 266 people
- Sponsor
- Novartis Pharmaceuticals
Liposuction, Bruising
EFFECTS OF TRANEXAMIC ACID IN TUMESCENT SOLUTION FOR LIPOSUCTION PROCEDURES
The goal of this trial is to evaluate the effect of adding Tranexamic Acid (TXA) to the tumescent solution used in arm liposuction on postoperative outcomes.
- Conditions
- Liposuction, Bruising, Inflammation, Skin Condition
- Trial name
- ARMTXA (NCT06648265)
- Testing
- Tranexamic Acid (Topical), Tumescent solution with dilute lidocaine and epinephrine
- Where
- Colombia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Stereotactic Body Radiation Therapy
Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases With Perilesional Edema in NSCLC
The purpose of this study is to determine whether stereotactic radiosurgery combination with Anlotinib is safe, effective in the treatment of limited brain metastases with Perilesional edema in non-small cell lung cancer.
- Trial name
- Rvision-001 (NCT04147728)
- Testing
- Anlotinib, Stereotactic Radiosurgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Branch Retinal Vein Occlusion with Macular Edema
Eylea and Lucentis for Macular Edema in Branch Retinal Vein Occlusion
Comparing time to recurrence of macular edema after an initial loading dose of at least three monthly anti VEGF injections (aflibercept or ranibizumab) for macular edema in BRVO.
- Trial name
- NCT03709745
- Testing
- Aflibercept Injection [Eylea], Ranibizumab Injection [Lucentis]
- Where
- Sweden
- Volunteers
- 110 people
- Sponsor
- St. Erik Eye Hospital
Breast Cancer Lymphedema
Effect of the Axillary Lymphatic /Vein Reflux Ratio on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the difference in the incidence of upper limb edema and dysfunction between the Preponderant lymphatic reflux group (high ratio of axillary lymphatic reflux to axillary vein reflux) and the…
- Trial name
- PLEDGE-R (NCT05246592)
- Testing
- Branches Sparing, None Branches Sparing
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Cirrhosis
A Study to Investigate Pharmacodynamics and Pharmacokinetics of OPC-41061 in Patients With Hepatic Edema
OPC-41061 at 3.75 mg/day or 7.5 mg/day will be orally administered once daily for 7 days to cirrhosis patients with ascites despite having received treatment with conventional diuretics and pharmacodynamics, pharmacokinetics…
- Trial name
- NCT01114828
- Testing
- OPC-41061
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Branch Retinal Vein Occlusion
Intravitreal Triamcinolone for Acute Branch Retinal Vein Occlusion
The purpose of this study is to determine whether intraocular injection of triamcinolone is effective in the treatment of macular edema in acute branch retinal vein occlusion.
- Trial name
- NCT00370266
- Testing
- Triamcinolone
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Diabetic Retinopathy, Macular Edema
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)
Researchers are looking for new ways to treat diabetic macular edema (DME). In this trial, researchers want to learn if a trial medicine called MK-8748 can treat DME.
- Trial name
- NCT07705607
- Testing
- MK-8748, Aflibercept
- Where
- 19 sites in United States
- Volunteers
- 1,104 people
- Sponsor
- Merck Sharp & Dohme LLC
Distal Radius Fractures, Edema Arm
Fluidotherapy in Patients With Distal Radius Fractures
Distal radius fractures are the most common fractures when looking at upper extremity fractures. The incidence of distal radius fractures is increasing day by day, and when looking at the databases of various countries, its…
- Conditions
- Distal Radius Fractures, Edema Arm, Pain
- Trial name
- NCT06272877
- Testing
- Fluidotherapy, conventional rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Venous Retinal Branch Occlusion, Central Retinal Vein Occlusion
Impact of Lucentis on Psychological Morbidity in Patients With Retinal Vein Occlusion
This is a prospective, single-center, non-randomized clinical study on the impact of intravitreally administered ranibizumab (Lucentis) treatment on vision-related functioning and emotional well-being in subjects with central or…
- Conditions
- Venous Retinal Branch Occlusion, Central Retinal Vein Occlusion, Retinal Vein Occlusion, Depression
- Trial name
- NCT01011374
- Testing
- ranibizumab (Lucentis)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Retina Associates of Cleveland, Inc
Macular Edema, Branch Retinal Vein Occlusion
A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Branch Retinal Vein Occlusion
This is a Phase III, multicenter, randomized, double-masked, active comparator-controlled, parallel-group study evaluating the efficacy, safety, and pharmacokinetics of faricimab administered by intravitreal (IVT) injection at…
- Trial name
- BALATON (NCT04740905)
- Testing
- Faricimab, Aflibercept
- Where
- 150 sites in United States, Argentina and 20 more
- Volunteers
- 553 people
- Sponsor
- Hoffmann-La Roche
Breast Cancer Lymphedema
Effect of ALND With Vein Branches Reservation on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the effects of axillary lymph node dissection with or without axillary vein branches reservation on the affected upper limb edema and dysfunction in breast cancer patients, and to explore…
- Trial name
- PLEDGE-Surgery (NCT05120180)
- Testing
- axillary lymph node dissection with vein branches reservation, axillary lymph node dissection without vein branches reservation
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Retinal Vein Occlusion
Efficacy and Safety of Ranibizumab in Japanese Patients With Retinal Vein Occlusion
The purpose of this study is to provide efficacy and safety data of 3 consecutive monthly intravitreal injections with 0.5 mg ranibizumab in Japanese patients with visual impairment due to macular edema secondary to retinal vein…
- Trial name
- RVO in Japan (NCT01377597)
- Testing
- ranibizumab
- Where
- 8 sites in Japan
- Volunteers
- 47 people
- Sponsor
- Novartis Pharmaceuticals
Branch Retinal Vein Occlusion
Study to Assess the Clinical Efficacy and Safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) in Patients With Branch Retinal Vein Occlusion (BRVO)
This is a phase III, double-masked, randomized, active-controlled, parallel-group, 52-week study to assess the efficacy and safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) compared to laser treatment in…
- Trial name
- VIBRANT (NCT01521559)
- Testing
- Macular Laser Photocoagulation, Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321)
- Where
- 56 sites in United States, Canada and 1 more
- Volunteers
- 183 people
- Sponsor
- Regeneron Pharmaceuticals
Retinal Vein Occlusion
Extended Follow-up of Patients With Macular Edema Due to Retinal Vein Occlusion
This study evaluates long-term safety in patients with macular edema due to Retinal Vein Occlusion (RVO) originally enrolled in the BRAVO \& CRUISE trials and subsequently followed in the HORIZON extension trial.
- Trial name
- RETAIN (NCT01198327)
- Testing
- ranibizumab, Peripheral Laser
- Where
- 6 sites in United States
- Volunteers
- 66 people
- Sponsor
- Peter A Campochiaro, MD