Clinical trials: ENT Surgery
Reaction; Anesthesia
Clinically Relevant Asymmetry of Bispectral Index
BIS for monitoring depth of anesthesia is usually obtained unilaterally. Obtaining BIS bilaterally revealed side differences in previous studies.
- Trial name
- NCT01289613
- Where
- Germany
- Volunteers
- 88 people
- Sponsor
- University Hospital Schleswig-Holstein
Nasal Polyps, Anesthesia
Auriculotherapy for Intraoperative Blood Pressure Control
The endoscopic surgery of the paranasal sinuses (FESS) requires careful control of arterial pressure to prevent bleeding of the nasal mucosa that may lead to a reduction in the visual field.
- Conditions
- Nasal Polyps, Anesthesia, Sinusitis, ENT Surgical Result - Nose Nasal Congestion
- Trial name
- AuriFESS (NCT06182982)
- Testing
- auricolotherapy
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Otorhinolaryngologic Neoplasms
Support Pathway for ENT Cancer Patients in a Support Care Day Hospital
Cancers of the upper respiratory / digestive tract are a major public health problem, ranking 5th among the most common cancers. Surgery plays a central role in the recommended treatments for this type of pathology.
- Trial name
- PAKO-HDJ (NCT06512662)
- Testing
- Consultations with paramedics
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Clinique Pasteur Lanroze
Cervico-Facial Surgery ENT Academic Medical and Surgical Training in France, Cervico-Facial Surgery ENT Medical Residency (Auvergne-Rhône-Alpes, Grand Est, Ile de France, Nouvelle Aquitaine and Provence-Alpes-Côte d'Azur Areas)
Impact of Covid-19 on Training for ENT and Cervico-Facial Surgery Residents in France
The impact of the Covid-19 pandemic on medical education is real but little known. ENT interns were directly affected by the management of Covid-19 patients (performing surgical tracheostomies), many conferences and trainings…
- Trial name
- NCT05158790
- Testing
- Questionnaire
- Where
- 6 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Workplace Violence, Perceived Safety
Workplace Violence and Safety Perception Among ENT Physicians in Turkey
This multicenter, cross-sectional survey study aims to evaluate the perceived level of safety and security against workplace violence among otolaryngology-head and neck surgery (ENT-HNS) physicians in Turkey.
- Conditions
- Workplace Violence, Perceived Safety, Occupational Health, Otolaryngology-Head and Neck Surgery Physicians
- Trial name
- NCT07311629
- Testing
- Online Survey Questionnaire
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
General Anesthesia
Multimodal Monitoring During General Anesthesia in ENT Surgery
This study evaluated whether using several monitoring methods together during general anesthesia could improve patient safety and help anesthesiologists adjust medication doses in adults undergoing ear, nose, and throat (ENT)…
- Trial name
- NCT07895836
- Testing
- Multimodal Anesthesia Monitoring (BIS, SPI, TOF), Standard Anesthesia Monitoring
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Barbara Verro
Cancer, Mouth
Oral Care Study of Postoperative Infections
Reduce the incidence of post-operative infections after ENT surgery and flap reconstruction by performing preoperative oral and dental care
- Trial name
- NCT04163029
- Testing
- Preoperative oral care
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
Carcinologic Ear, Nose, and Throat (ENT) Surgery
Intravenous Lidocaine in Carcinologic ENT Surgery: A Trial for Evaluation of Opioid Saving Strategy and Chronic Post-surgical Pain (ELICO)
Lidocaine, local anesthetic used for more than five decades, is being intravenously administered aiming at managing pain in different types of surgeries with promising results.
- Trial name
- ELICO (NCT02894710)
- Testing
- Lidocaine 20mg/ml
- Where
- 2 sites in France
- Volunteers
- 143 people
- Sponsor
- Hospices Civils de Lyon
Hypothyroidism, Neoplasms
Levothyroxine Treatment for Subclinical Hypothyroidism After Head and Neck Surgery
Patients that require treatment for cancers of the head and neck often require a combination of surgery and/or radiation and chemotherapy.
- Conditions
- Hypothyroidism, Neoplasms, Postoperative Complications
- Trial name
- LSHT (NCT02548715)
- Testing
- Levothyroxine
- Sponsor
- University of Alberta
Anesthesia, General
The Effect of BIS-guided Propofol Induction on Hemodynamic Response in Patients With Cardiac Risk.
Anesthesia induction will be started by monitoring ECG, non-invasive artery monitoring, peripheral oxygen saturation and BIS for all patients who are taken to the operating room without sedation.
- Trial name
- NCT04729465
- Testing
- Propofol, Bispectral Index Monitor
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Postoperative, Surgery, Oral
Licorice Versus Sugar-water Gargling for Pain in Patients Recovering From Ear-Nose-Throat and Maxilla-Facial Surgery
Our primary aim is to determine whether licorice gargling provides meaningful analgesia after oral surgery. Specifically, we propose to test the primary hypothesis that gargling with licorice solution reduces pain after oral…
- Trial name
- NCT02968823
- Testing
- Licorice, Sugar water
- Where
- Austria
- Volunteers
- 127 people
- Sponsor
- Medical University of Vienna
Frailty
SCM Muscle as a Marker for Frailty in Patients Undergoing ENT Surgery
This study focuses on evaluating the relationship between physical frailty and measurements of the muscles of the neck in patients undergoing non-cancer Head and Neck surgery.
- Trial name
- NCT06704256
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anxiety State, Pain
The Effect of Acupressure on Preoperative Anxiety and Postoperative Pain and Nausea-Vomiting
The study was conducted in the ENT Clinic of Mersin Şehir Training and Research Hospital between June 1 and December 1, 2021, with a total of 60 adult patients, 30 in the study group and 30 in the control group, who met the…
- Conditions
- Anxiety State, Pain, Vomiting, Nausea
- Trial name
- Acupress (NCT06040411)
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Mucopolysaccharidosis (MPS)
Mucopolysaccharidosis (MPS) I, II, and VI Screening in a High-Risk Population With Previous Surgical Repair or Presence of Inguinal and/or Umbilical Hernia in Combination With Pediatric ENT Surgery (The HATT Project)
Mucopolysaccharidosis (MPS) type II (MPS II; Hunter syndrome) is a rare, X-linked disease caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase (I2S) and occurs almost exclusively in boys, with an incidence of…
- Trial name
- NCT02095015
- Where
- 14 sites in United States, Canada and 5 more
- Volunteers
- 159 people
- Sponsor
- Shire
Tonsil Hypertrophy
Effect of the Combination of Dexamethasone and BIS Monitoring on Reducing Postoperative Nausea and Vomiting in Children
This study will investigate the impact of combining dexamethasone and bispectral index (BIS) monitoring on the incidence of postoperative nausea and vomiting, emergence delirium and recovery trajectories in children undergoing…
- Trial name
- BISDEX (NCT07299435)
- Testing
- BIS monitoring
- Where
- 5 sites in Czechia
- Volunteers
- 1,508 people
- Sponsor
- University Hospital Ostrava
Anaesthesia, General, Anesthesia, Intravenous
Oxygenation by 100% Oxygen Via High Flow Nasal Cannula in Surgical Patients
Oxygenation with high-flow nasal cannula with 100% oxygen has only been evaluated in a limited number of studies. Although data are convincing it is of importance to evaluate this new concept in our department before implementing…
- Conditions
- Anaesthesia, General, Anesthesia, Intravenous, Ventilation
- Trial name
- NCT02706431
- Testing
- Hyperventilation
- Volunteers
- 31 people
- Sponsor
- Karolinska University Hospital
Head and Neck Cancer (H&N), Cancer of the Head and Neck
Online Perioperative Education Program on Patient Satisfaction and Clinical Outcomes for Head and Neck Surgery
CareOrbit is a digital perioperative patient-education and care navigation platform developed by the St. Louis-based venture Total Orbit in collaboration with Washington University's CORTEX Business Incubator.
- Trial name
- NCT07848841
- Testing
- CareOrbit, Standard perioperative education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Tonsillectomy
Etoricoxib in Ear Nose Throat Surgery
The aim of this study is to test the analgesic efficacy of etoricoxib (90 mg or 120 mg qd. perioperatively) for post-operative pain relief.
- Trial name
- NCT00756873
- Testing
- Administration of etoricoxib
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- University of Regensburg
Colorectal Neoplasms, Urologic Neoplasms
A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery
This is a prospective, single center, multispecialty study that aimed to evaluate the clinical feasibility and safety of single port surgery and NOTES (mainly transanal and transoral surgery) using a novel single port robotic…
- Conditions
- Colorectal Neoplasms, Urologic Neoplasms, Urologic Diseases, Nasopharyngeal Neoplasms
- Trial name
- NCT03010813
- Testing
- Robotic single port surgery and NOTES
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Chinese University of Hong Kong