Clinical trials: ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION
Lung Cancer
Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Lymph Node Staging in Patients With Non-small Cell Lung Cancer Pursuing Stereotactic Body Radiotherapy (SBRT)
It is reported that more than 90,000 patients died of lung cancer and more than 20% of them were older than 80 years in North America.
- Trial name
- NCT01786590
- Testing
- EBUS-TBNA
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University Health Network, Toronto
Non Small Cell Lung Cancer
Risk Factors of Medistinal Metastasis in Endoscopic Staging of Lung Cancer
The purpose of this study is to investigate risk factors for mediastinal lymph node metastasis in potentially operable non-small cell lung cancer in order to find indications for endoscopic mediastinal staging.
- Trial name
- NCT02991924
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- National Cancer Center, Korea
Mediastinum
EBUS-TBNA vs EUS-B-FNA for Needle Aspiration of Mediastinal Lesions
Endobronchial Ultrasound Guided Transbronchial Needle aspiration (EBUS-TBNA) is a firmly established modality for diagnostic evaluation of mediastinal lesions.
- Trial name
- TEAM (NCT02704078)
- Testing
- EBUS-TBNA, EUS-B-FNA
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
EBUS-TBNA Training Methods
Evaluation of Clinical Endobronchial Ultrasound Skills Following Clinical Versus Simulation Training.
Bronchoscopy is a procedure whereby a small flexible camera is used to inspect and biopsy abnormalities in the lungs. Linear endobronchial ultrasound with transbronchial needle aspiration (EBUS-TBNA) is a revolutionary diagnostic…
- Trial name
- NCT01269931
- Testing
- EBUS-TBNA
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Non Small Cell Lung Cancer, Non Small Cell Lung Cancer (NSCLC)
Liquid Biopsy Assay of EBUS-TBNA Supernatant Fluid for Diagnosing Lung Cancer
Background and aim: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the gold standard of lung cancer staging, yet up to 15% of procedures produce inadequate samples for definite diagnosis or…
- Conditions
- Non Small Cell Lung Cancer, Non Small Cell Lung Cancer (NSCLC), Lung Cancer (NSCLC), Lung Cancer - Non Small Cell
- Trial name
- NCT06889467
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Barzilai Medical Center
Ultrasound, Complication
Safety of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration : A Prospective Study
The purpose of this study is to find all kinds of complications and it's frequency related to the Endobronchial Ultrasound- Transbronchial Needle Aspiration (EBUS-TBNA) and to evaluate associated risk factors in patients who…
- Trial name
- NCT01597869
- Testing
- Endobronchial ultrasound
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Samsung Medical Center
Sedation Complication, EBUS Guided Transbronchial Needle Aspiration
The Decisiveness of MFI-11 in Predicting Complications in Patients > 65 Years Who Underwent EBUS-TBNA Under Sedation
The aim is to evaluate the feasibility of MFI-11, one of the comprehensive frailty tests, before EBUS-TBNA. The secondary aim is to evaluate the usefulness of MFI-11 in predicting complications in risk assessment before EBUS-TBNA.
- Conditions
- Sedation Complication, EBUS Guided Transbronchial Needle Aspiration, Monitored Anesthesia Care, Elderly Patients
- Trial name
- NCT06174168
- Testing
- Modified Frailty Index -11
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Lung Cancer
Mutation Detection of EBUS-TBNA Specimens Using NGS
The objective of the study was to compare the value of routine gene testing and next-generation sequencing (NGS) in detecting gene mutations of small specimens obtained by endobronchial ultrasound transbronchial needle aspiration…
- Trial name
- NCT02420405
- Testing
- Routine gene testing, Next-generation sequencing
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jiayuan Sun
Lung Cancer With Mediastinal Lymph Node Involvement
Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging
A DNA hypermethylation of the gene locus SHOX2 can be frequently found in lung cancer tissue. The purpose of this study is to determine whether the assessment of the hypermethylation level of SHOX2 in specimens obtained by…
- Trial name
- NCT01653002
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Essen
Sarcoidosis, Lymphoma
Effect of Needle Size in Diagnostic Yield of EBUS-TBNA in Sarcoidosis and Lymphoma
The guided FNA by endobronchial ultrasound ( Endobronchial Ultrasound guided transbronchial Needle Aspiration or EBUS-TBNA) is a minimally invasive technique with an established role in the staging of lung cancer 1, and in the…
- Conditions
- Sarcoidosis, Lymphoma, Adenopathy Hilar
- Trial name
- NCT03573362
- Testing
- ViziShot FLEX 19G needle, Vizishot 22G needle (standard)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lymphadenopathy Hilar, Lymphadenopathy Mediastinal
The Comparison of EBUS-TBNA, TBMC Via a Tunnel, and TBFB Via a Tunnel in Diagnosing Mediastinal Lymphadenopathy.
The goal of this prospective, multi-centre, randomised controlled clinical study is to compare the diagnostic yield and safety of the three biopsy techniques (EBUS-TBNA, EBUS-TBMC via a tunnel, and EBUS-TBFB via a tunnel) in…
- Trial name
- NCT06262620
- Testing
- EBUS-TBNA, EBUS-TBMC via a tunnel, EBUS-TBFB via a tunnel
- Where
- China
- Volunteers
- 552 people
- Sponsor
- China-Japan Friendship Hospital
Intrathoracic Lymphadenopathy
Rapid On-site Evaluation of Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Samples by Pulmonologists
The study is aimed at verifying if a pulmonologist in training can reliably assess the adequacy of EBUS-TBNA samples from intrathoracic lymphadenopathy after a period of training provided by an experienced pathologist.
- Trial name
- NCT03232684
- Testing
- Rapid on-site evaluation
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Sarcoidosis
A Study Evaluating the Diagnostic Yield and Safety of the ProCore vs Conventional EBUS-TBNA Needle in Subjects With Suspected Sarcoidosis
This study evaluates the yield and safety of two different needles for performing endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) in patients with sarcoidosis.
- Trial name
- NCT03656003
- Testing
- Procore biopsy needle, Conventional biopsy needle
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Lung Cancer, Lung; Node
Remifentanil Target Controlled Infusion Versus Standard of Care for Conscious Sedation During EBUS-TBNA
Background: endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure for diagnosing and staging mediastinal lymph node lesions in lung cancer.
- Conditions
- Lung Cancer, Lung; Node, Sedation Complication, Endoscopy
- Trial name
- NCT06033729
- Testing
- Remifentanil TCI, Midazolam injection, Fentanyl
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Scarlata, Simone, M.D.
Mediastinum
Value of Rapid on Site Evaluation During EBUS-guided TBNA in the Diagnosis of Mediastinal Lesions
This prospective study will include 30 patients with hilar/mediastinal lymph nodes detected by thoracic CT either there was a known lung malignancy (for staging purpose) or not (for diagnosing purpose).
- Trial name
- NCT02690610
- Testing
- EBUS TBNA of mediastinal lesions or lymph nodes
- Where
- Egypt
- Volunteers
- 67 people
- Sponsor
- Tanta University
Sarcoidosis
An RCT of 19G EBUS-TBNA Needle in Suspected Sarcoidosis
Sarcoidosis is an idiopathic disorder characterized by granulomatous inflammation involving various organ systems. The lung and mediastinal lymph nodes are the most commonly involved structures in sarcoidosis.
- Trial name
- GUESS (NCT04770948)
- Testing
- 19 gauge needle, 22 gauge needle
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Lung Neoplasm
RCT Comparing 19Ga vs 22Ga EBUS-TBNA Needles in Carcinoma.
EBUS-TBNA is often the sole diagnostic test applied in patients with stage IV lung cancer. A limitation of the TBNA needle when using a 22 Gauge needle is the limited ability to procure adequate histological samples.
- Trial name
- NCT02906280
- Testing
- EBUS-TBNA needle
- Where
- Belgium
- Volunteers
- 78 people
- Sponsor
- KU Leuven
Lung Neoplasms
One Step Nucleic Acid Amplification in Endobronchial Ultrasound-guided Needle Aspiration Samples
The aim of our study is to investigate if CK19 mRNA-detection via OSNA can accurately detect lymph node metastases in lung cancer patients using EBUS-TBNA samples.
- Trial name
- NCT02157857
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital, Essen
Sarcoidosis Lung, Pulmonary Sarcoidosis
Comparative Diagnostic Yield of Endobronchial Cryo Biopsy vs Forceps Biopsy in Patients With Suspected Sarcoidosis
Sarcoidosis is a multi-systemic granulomatous disease of unknown cause that is characterized by the formation of non-caseous epithelioid cell granulomas.
- Trial name
- CREBS (NCT06853834)
- Testing
- Cryobiopsy with liquid nitrogen, Endobronchial Forceps Biopsy
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Lung Cancer
Incidence of SCLN Metastasis in Patients Referred for EBUS-TBNA
Evaluation of the anatomic extent of a primary lung cancer and presence of metastasis are essential for selection of an appropriate management strategy.
- Trial name
- NCT03087305
- Testing
- Supraclavicular lymph node ultrasound
- Where
- United States
- Sponsor
- University of Minnesota