Clinical trials: ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION
Bronchoscopy
Dexmedetomidine for Sedation of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Preventing hypoxemia is one of the major goal of studies for bronchoscopic sedation. Dexmedetomidine is a sedative agents via α2 adrenergic agonist, with little respiratory suppression.
- Trial name
- NCT03521505
- Testing
- Dexmedetomidine arm, Propofol arm
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Mediastinal Lymphadenopathies
Diagnostic Yield and Safety of Confocal Laser Endomicroscopy-Assisted Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
Comparison of the Diagnostic Yield and Safety Between Confocal Laser Endomicroscopy-Assisted Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration and Endobronchial Ultrasound-Guided Transbronchial Mediastinal…
- Trial name
- COLLEBERATIONⅢ (NCT07040670)
- Testing
- Confocal laser endomicroscopy-assisted endobronchial ultrasound-guided transbronchial needle aspiration, Endobronchial ultrsound-guided Mediastinal cryobiopsy
- Volunteers
- 469 people
- Sponsor
- China-Japan Friendship Hospital
Mediastinal Lymphadenopathy
EBUS-TBNA vs Acquire TBNB
This study aims to determine whether a new type of needle used for sampling lymph nodes (glands) around the airways of the lung, during a procedure called an endobronchial ultrasound (EBUS, provides more or better quality tissue…
- Trial name
- NCT04200105
- Testing
- EBUS-TBNA, Acquire TBNB
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Malignant Neoplasms of Respiratory and Intrathoracic Organs, Lung Neoplasm
Radial-Probe Endobronchial Ultrasound in Detecting Atelectasis in Patients Undergoing Peripheral Bronchoscopy
This trial studies how well radial-probe endobronchial ultrasound works in detecting the complete or partial collapse of the lung in patients undergoing peripheral bronchoscopy.
- Trial name
- NCT03523689
- Testing
- Bronchoscopy, Radial Probe Endobronchial Ultrasound
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- M.D. Anderson Cancer Center
Hemodynamic Stability, Pulmonary Diseases or Conditions
A Study Comparing Sevoflurane and Propofol in Patients Undergoing Endobronchial Ultrasound Guided Needle Aspiration
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure used to obtain samples from mediastinal and hilar lymph nodes or lung parenchymal lesions for diagnostic and staging…
- Conditions
- Hemodynamic Stability, Pulmonary Diseases or Conditions, Complication of Anesthesia
- Trial name
- NCT07338578
- Testing
- propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi
Lung Cancer
Endobronchial Ultrasound-transbronchial Needle Aspiration (EBUS-TBNA) Sample Division
EBUS-TBNA specimen are used for lung cancer diagnosing and staging, as well for molecular analysis. The purpose of this study is to evaluate if samples from on lymph node site can be divided for diagnosis and molecular analysis.
- Trial name
- NCT02157194
- Where
- Germany
- Volunteers
- 88 people
- Sponsor
- University Hospital, Essen
Lung Cancer
Feasibility of Evaluating Gene Alteration Analysis Using Samples Obtained by EBUS-TBNA in Patients With Lung Cancer
Lung cancer is the leading cause of death in the world. Overall 5-year survival rate is fewer than 10% and the effectiveness of conventional chemotherapy is limited.
- Trial name
- NCT01487603
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University Health Network, Toronto
High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION
High-Flow Nasal Oxygyen Therapy During Sedated Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration(EBUS-TBNA)
This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided…
- Conditions
- High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Sedation, Sedation Complication
- Trial name
- NCT07760727
- Testing
- High-Flow Nasal Oxygen Therapy, Conventional Oxygen Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Lymphadenopathy, Lung Cancer
EBUS-TBNA vs Flex 19G EBUS-TBNA
This is a prospective randomised diagnostic clinical study to determine whether the use of a new flexible sampling needle can improve the yield of endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA).
- Conditions
- Lymphadenopathy, Lung Cancer, Sarcoidosis, Lymphoma
- Trial name
- NCT02916459
- Testing
- 21G EBUS-TBNA needle, Flexible 19G EBUS-TBNA needle
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Heidelberg University
Mediastinal Metastases of Lung Cancer
Diagnostic Value and Safety of Combined Biopsy for Mediastinal Metastasis of Lung Cancer
The study is aimed o evaluate the diagnostic performance and treatment guidance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) combined with transbronchial mediastinal cryobiopsy (EBUS-TBMCB) in…
- Trial name
- NCT07488507
- Testing
- EBUS-TBMCB
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Third Military Medical University
Neoplasm of Lung
Multimodalitic Imaging in the N-stage of Lung Cancer
This study aims to evaluate the diagnostic efficacy and differences between 18F-FDG PET/CT and MR STIR sequences combined with EBUS-TBNA, 18F-FDG PET/CT combined with EBUS-TBNA, and MR STIR sequences combined with EBUS-TBNA …
- Trial name
- NCT05840094
- Testing
- 18F-FDG, MR STIR, EBUS-TBNA
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Midazolam, Remimazolam
Trial Evaluating the Efficacy of Remimazolam in Endobronchial Ultrasound Guided Transbronchial Needle Aspiration
Study to evaluate the efficacy and safety of remimazolam in patients undergoing endobronchial ultrasound-guided transbronchial needle aspiration Primary Outcome Evaluate and compare the success of the procedure in patients…
- Trial name
- REST (NCT06275594)
- Testing
- Byfavo, Midazolam
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Yeungnam University Hospital
Lung Cancer
Genotyping of Ebus-tbna Supernant Cell-free Dna in Nsclc
The wide uptake of "liquid biopsy" diagnostics in the care of advanced cancer patients highlights the desire for improved access to tumor allowing accurate tumor genotyping (1).
- Trial name
- CELTICS (NCT04624373)
- Testing
- Molecular analysis of surnatant
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Lymph Node Disease
22G-ProCore vs 22G-Standard Needle in Diagnosis of Lymphadenopathy by EBUS-TBNA
The aim of this study is to compare the performance of 22G-ProCore and 22G-Standard needle in diagnosis of mediastinal and hilar lymphadenopathy via EBUS-TBNA with the purpose to explore the optimal technique for obtaining…
- Trial name
- NCT03903471
- Testing
- 22G-ProCore Endobronchial Ultrasound Needle, 22G-Standard Endobronchial Ultrasound Needle
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Jiayuan Sun
Endobronchial Ultrasound
Chlorhexidine Mouthrinse Before EBUS-TBNA
The purpose of this study is to investigate whether chlorhexidine mouthrinse is effective in preventing microbial contamination during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).
- Trial name
- CHX_EBUS (NCT04718922)
- Testing
- Chlorhexidine Gluconate 0.12 % Mouthwash
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Seoul National University Hospital
Lung Neoplasms, Bronchoscopy
Feasibility and Preliminary Performance of an AI Prototype for Digital ROSE During EBUS-TBNA and Peripheral TBNA: a Prospective Pilot Study (AI-ROSE-FEAS)
Rapid On-Site Evaluation (ROSE) of cytological slides obtained during EBUS-TBNA improves diagnostic yield by providing real-time adequacy assessment and preliminary diagnostic orientation after each needle pass.
- Conditions
- Lung Neoplasms, Bronchoscopy, AI (Artificial Intelligence), Mediastinal ( Chest) Masses
- Trial name
- AI-ROSE-FEAS (NCT07662967)
- Testing
- ROSE
- Volunteers
- 65 people
- Sponsor
- Azienda Ospedaliera di Rilievo Nazionale A.Cardarelli
Lung Cancer, Sarcoidosis
Comparison of Three Different Puncture Techniques in EBUS-TBNA
The purpose of this study was to compare the accuracy and sensitivity of slow-pull capillary technique, traditional suction aspiration and non negative pressure puncture in the diagnosis of mediastinal and/or hilar lymph node…
- Conditions
- Lung Cancer, Sarcoidosis, Tuberculosis
- Trial name
- NCT05628454
- Testing
- Endobronchial ultrasound-guided transbronchial needle Slow-pull capillary sampling, Endobronchial ultrasound-guided transbronchial needle aspiration, Endobronchial ultrasound-guided transbronchial needle capillary sampling
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Beijing Friendship Hospital
Mediastinal Lymphadenopathy, Hilar Lymphadenopathy
Conventional Versus Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis of Hilar/Mediastinal Lymphadenopathies
The main purpose of the present study is to assess whether the sensitivity of Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) is superior to that of conventional TBNA in the diagnosis of hilar/mediastinal…
- Conditions
- Mediastinal Lymphadenopathy, Hilar Lymphadenopathy, Lymphoma, Lung Neoplasms
- Trial name
- NCT01658280
- Testing
- EBUS-TBNA
- Where
- Italy
- Volunteers
- 253 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Non-small Cell Lung Cancer
Endobronchial Ultrasound vs Mediastinoscopy in NSCLC
Proper staging of Lung cancer is of paramount concern when determining a treatment regime. Currently the assessment of surgical candidacy is performed with the staging process, mainly the mediastinoscopy.
- Trial name
- NCT00372203
- Testing
- Endobronchial Ultrasound Guided Transthoracic Needle Biopsy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Sarcoidosis, Pulmonary
Diagnostic Value of EBUS-Guided Transbronchial Mediastinal Cryobiopsy Versus Conventional Bronchoscopic Approaches for Stage I/II Sarcoidosis
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), combined with endobronchial biopsy (EBB) and/or transbronchial lung biopsy (TBLB), and endobronchial ultrasound-guided transbronchial mediastinal…
- Trial name
- NCT07246876
- Testing
- EBUS-TBNA-based sampling methods, EBUS-TBMC based sampling method
- Where
- China
- Volunteers
- 469 people
- Sponsor
- China-Japan Friendship Hospital