Clinical trials: EEG Brain Oscillations
Alzheimer Disease, Working Memory
Induction and Stabilization of Gamma Oscillations With 40 Hz External Brain Stimulation
The goal of the present studies is to develop and validate novel stimulation protocols for the entrainment of gamma oscillations, which are associated with many cognitive functions and critically involved in cognitive impairment…
- Conditions
- Alzheimer Disease, Working Memory, EEG Brain Oscillations
- Trial name
- NCT06680154
- Testing
- Transcranial alternating current stimulation, Theta burst stimulation
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Alzheimer's Disease, 40 Hz Stimulation
Effects of Combined 40 Hz Audio-visual Stimulation and Cognitive Games on Alzheimer's Disease
In addition to ongoing drug treatments for Alzheimer Disease (AD), protective approaches that can halt the progression of the disease are of particular importance.
- Conditions
- Alzheimer's Disease, 40 Hz Stimulation, EEG Brain Oscillations
- Trial name
- NCT06595511
- Testing
- Sensory Entrainment-Integrated Cognitive Game Kit
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Alzheimer Disease, Early Onset
The Resting-state EEG Gamma Oscillations in Alzheimer's Disease
The literature suggests a strong association between amyloid accumulation and gamma alterations, emerging gamma activity as a biomarker candidate for Alzheimer's pathology.
- Trial name
- EEG (NCT05989087)
- Testing
- CSF
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Görsev Yener, MD, PhD
Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic
Acoustic Stimulation During Sleep: Effects on Memory and p-tau217 in MCI
The goal of this clinical trial is to determine whether acoustic stimulation during sleep can enhance slow-wave sleep (SWS), improve cognitive function, and reduce AD-related pathology in individuals with mild cognitive…
- Conditions
- Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic, Cognitively Unimpaired
- Trial name
- PAS-MCI (NCT07529015)
- Testing
- Plase-Locked Acoustic Stimulation during slow-wave sleep
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Chronic Pain, Neck Pain
Examining the Effect of Lateralization Imagery Training on EEG Brain Oscillations in Individuals With Chronic Neck Pain
In this study, it was planned to investigate the effectiveness of lateralization and imagery training in individuals with chronic neck pain.
- Trial name
- NCT06679335
- Testing
- Lateralization Imagery Training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
mTBI
Detection and Amelioration of Gamma Oscillation Abnormalities in Blast-Related Brain Injury
Combat Veterans of post-9/11 conflicts have experienced serious cognitive and emotional problems resulting from exposure to blasts.
- Trial name
- DAGABBI (NCT03836976)
- Testing
- Auditory gamma sensory stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
EEG Brain Oscillations, Alzheimer's Disease (AD)
Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults
This study aims to evaluate the effects of endogenous gamma non-flickering light stimulation on resting-state EEG rhythms and cognitive function in cognitively healthy older adults.
- Conditions
- EEG Brain Oscillations, Alzheimer's Disease (AD), Cognitively Normal Older Adults
- Trial name
- NCT06715995
- Testing
- Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Terminal Illness, End-of-Life Care
Non-Invasive Detection and Preservation of Neurocognitive Signals in the Peri-Death Period Using Brain-Computer Interface and Artificial Intelligence
Background: Recent electroencephalography (EEG) data indicate that the transition from clinical death to cellular death is marked by highly organized neurophysiological events, including significant surges in gamma-band power…
- Conditions
- Terminal Illness, End-of-Life Care, Death, Brain Death
- Trial name
- NeuroCogPresv (NCT07477028)
- Volunteers
- 20 people
- Sponsor
- Noah Tech, Corp.
Schizophrenia, Schizoaffective Disorder
Clonazepam Effects on Brain Oscillations and Cognition in Schizophrenia
Cognitive deficits are some of the most prominent and disabling symptoms of schizophrenia. Evidence suggests that schizophrenia involves alterations to the functioning of a neural system under the control of a brain chemical…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- KGB (NCT03061136)
- Testing
- Clonazepam
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Obsessive Compulsive Disorder (OCD), Treatment Resistant Obsessive Compulsive Disorder
Brain-Oscillation Synchronized Stimulation of the DMPFC
This trial aims to obtain initial evidence about the clinical efficacy and modulation of neurophysiological markers in obsessive compulsive disorder (OCD) using personalized (i.e., electroencephalography (EEG)-triggered)…
- Trial name
- BOSS-OCD (NCT06942559)
- Testing
- EEG-Triggered Repetitive Transcranial Magnetic Stimulation (rTMS), Non-EEG Triggered Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Centre for Addiction and Mental Health
Stroke
Stroke Therapy With Brain Oscillation Synchronized Stimulation
This randomized, controlled, double-blind clinical pilot trial investigates the therapeutic potential of a novel personalized therapeutic brain-stimulation protocol in chronic stroke patients with spasticity.
- Trial name
- STROKEBOSS (NCT05005780)
- Testing
- Negative peak triggered 100 Hz triplet burst TMS, 1 Hz rTMS
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Tuebingen
Schizophrenia
Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia
People with schizophrenia often have problems with attention, learning and memory and other cognitive abilities that interfere with their work and school performance.
- Trial name
- NCT04267003
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Cognitive Deficit
Studying the Effects of Brain Stimulation on Cognitive Control and Associated EEG in Human Subjects.
This is a basic neuroscience study of modulating brain oscillations involved in cognitive control. We will record brain signals and stimulate specific regions of the brain in human participants who are undergoing monitoring for…
- Trial name
- NCT05251454
- Testing
- Brain Stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Cincinnati