Clinical trials: E-cigarette Use
Electronic Cigarette Use
Effects of Social Media Use on Young Adults' E-Cigarette Use
The goal of this clinical trial is to test the effects of social media use on e-cigarette use in young adults who use e-cigarettes.
- Trial name
- NCT06142877
- Testing
- Social Media Use Reduction
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking
Effect of Electronic Cigarettes on Platelets, Endothelium and Inflammation
The primary purpose of this study is to evaluate the acute effects of electronic cigarette (e-cigarette) smoking on measurable biomarkers of platelet function, vascular endothelial function and inflammation in healthy active…
- Trial name
- NCT02662075
- Testing
- E-cigarette/tobacco Smoking Exposure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Healthy Smokers, Smoking Cessation
Efficacy and Safety of an Electronic Nicotine Delivery Device (E-Cigarette)
The study's major aim is to investigate the ability of a commercial Electronic Nicotine Delivery Device (E-Cigarette) to induce long-term smoking reduction/abstinence in smokers unwilling to quit.
- Trial name
- NCT01164072
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Catania
Tobacco Smoking
E-cigarette Harm Reduction Among PLWHA in South Africa
The purpose of this pilot randomized controlled trial study aims to address the unmet need for feasible and efficacious strategies for reducing combustible cigarette (CC) use among people living with HIV/AIDS (PLWHA) in South…
- Trial name
- NCT06169813
- Testing
- Nicotine Replacement Therapy (NRT), E-Cigarette (EC), Counseling
- Where
- South Africa
- Volunteers
- 106 people
- Sponsor
- NYU Langone Health
Smoking Cessation, Obesity and Obesity-related Medical Conditions
Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy
This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.
- Trial name
- CRESCENT (NCT06948058)
- Testing
- Electronic Cigarettes (EC), Nicotine replacement therapy (NRT)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brown University
Vaping
Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents
The aim of this study is to determine if graphic messages prevent future vaping use among African American and Latino adolescents.
- Trial name
- NCT04899999
- Testing
- Financial reward graphic message, Health reward graphic message, Self-efficacy graphic message
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Electronic Cigarette Use, Pulmonary Disease
Factors That Impact the Relationship Between Pulmonary Status and Actual Electronic Cigarette Use
Secondary data analysis will be performed as our approach to complete the study. A nationally representative dataset (BRFSS, 2017) will be used to answer the above hypotheses.
- Trial name
- NCT04135404
- Testing
- health-related telephone surveys
- Volunteers
- 400,000 people
- Sponsor
- University of Alabama at Birmingham
Second Hand Tobacco Smoke
Study to Evaluate Constituents in Exhaled Breath and Room Air From Use of E-vapor Products and Conventional Cigarettes
An open-label, single center, three-arm observational study to examine emissions from e-cigarettes versus conventional cigarettes under three environmental settings of typical residential, office and hospitality facilities.
- Trial name
- NCT03605641
- Testing
- JUUL, VUSE Solo, Conventional Cigarette
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Tobacco Use Disorder, Nicotine Dependence
TUBSIS 2.0 - Tobacco Use Behavioral Support and Intervention System
Background: Tobacco smoking and vaping remains public health concern, with many adults continuing to experience difficulties accessing appropriate support for smoking cessation in Switzerland and Türkiye.
- Conditions
- Tobacco Use Disorder, Nicotine Dependence, Vaping, Smoking Tobacco
- Trial name
- TUBSIS_2_0 (NCT07568483)
- Testing
- TUBSIS 2.0
- Where
- Switzerland
- Volunteers
- 406 people
- Sponsor
- University of Zurich
Smoking, Cigarette, Electronic Cigarettes
Evaluating New Nicotine Standards for Cigarettes - Project 3
This study is designed to examine how the nicotine content of cigarettes and the nicotine concentration and flavors in e-liquids influence responses to and use of these products in adolescent smokers.
- Trial name
- CENIC2-P3 (NCT03194256)
- Testing
- Spectrum Research Cigarettes
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brown University
Substance Use Disorder, Alcohol Use Disorder
Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP
Background: People who will participate in research studies need to undergo proper screening, evaluation, and assessment (SEA). SEA helps keep those who participate in studies safe. It also helps ensure accurate study results.
- Trial name
- NCT06552741
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation, Electronic Cigarette Use
The Avenues Study: Dual Use Cessation
The overarching goal of this research is to determine the most effective approach for helping dual users of cigarettes and electronic nicotine delivery systems (ENDS) quit smoking.
- Trial name
- NCT06474299
- Testing
- Varenicline, Nicotine patch, Dual Focused Cessation Counseling
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Wisconsin, Madison
Vaping
Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study
The purpose of this study is to assess the effects of non-invasive vagus nerve stimulation (nNVS) on cognitive functioning in the users of e-cigarettes or vaping products.
- Trial name
- nVNS (NCT06804109)
- Testing
- Active nVNS, Control nVNS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Temple University
Smoking, Smoking Behaviors
CSD190203: A Study to Determine Subject Puffing Patterns of an Electronic Nicotine Delivery System in an Ambulatory Setting
This study will be a single-center, randomized, controlled, open-label, parallel 2-cohort study to evaluate the puffing patterns of individuals switching from a similar usual brand (UB) Electronic Nicotine Delivery System (ENDS)…
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Trial name
- NCT04104152
- Testing
- CSD1902-11, CSD1902-12, CSD1902-13
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
Vaping and Smoking Withdrawal Project
The proposed research, which will systematically and comprehensively characterize the withdrawal among daily vapers compared to daily smokers of combustible cigarettes, filling critical gaps in the understanding of electronic…
- Trial name
- VASP (NCT05772845)
- Testing
- Acute (24-hour) abstinence, Ad libitum smoking/vaping
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Marijuana Dependence
Vaping THC From Electronic Cigarettes
This study aims to understand THC pharmacology and the safety of cannabis vaping, including the pharmacology and safety of co-administration of nicotine and THC.
- Trial name
- V-PAX (NCT02955329)
- Testing
- Nicotine, Cannabis, PAX Loose Leaf Vaporizer
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking, Healthy
In-vivo Effects of E-cigarette Aerosol on Innate Lung Host Defense
While e-cigs are commonly represented as safer alternatives to tobacco cigarettes, little is known regarding the health effects of their short- or long-term use.
- Trial name
- Cinimic (NCT03700892)
- Testing
- Cinnamaldehyde e-liquid, PG/VG e-liquid
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tobacco Smoking
E-cigarettes to Promote Smoking Reduction Among Individuals With Schizophrenia
The purpose of this study is to assess if access to an electronic nicotine delivery device, or e-cigarette, in addition to nicotine patch (21 mg) can help reduce cigarette smoking among individuals diagnosed with schizophrenia…
- Trial name
- NCT02918630
- Testing
- Nicotine Patch, E-cigarette
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The University of Texas Health Science Center, Houston
Smoking, Asthma
E-cigarettes for Harm Reduction in Adults With Asthma
Smoking is the main cause of preventable disease and death in the US and impacts respiratory illnesses including COPD and asthma.
- Conditions
- Smoking, Asthma, Electronic Cigarette Use, Cigarette Smoking
- Trial name
- SWAP (NCT05278065)
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Brown University
Vaping, Underage
Human Factors Validation and Usability Testing of the IKE Age-Gating System
A multi-center human factors validation study to demonstrate the function of the IKE Bluetooth system on a chip (SoC) and mobile applications ability to age-gate a device, accurately identify an individuals age, race/ethnicity…
- Trial name
- NCT06952569
- Testing
- IKE System
- Where
- 4 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- IKE Tech