Clinical trials: Dyspnoea
COPD
Effect of Sleep Deprivation on Breathlessness and Exercise Capacity in COPD
This is a randomized controlled cross-over trial designed to measure the effect of one night's sleep deprivation on exercise endurance, ventilation and breathlessness in outpatients with COPD.
- Trial name
- NCT04997200
- Testing
- One night's sleeplessness
- Where
- 2 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Skane University Hospital
Dyspnea
Breathlessness Relieved by Employing Medical Air to be Titrated by Hospitalized Patients to Improve Inpatient Experience
The BREATHE-easy is a randomized control trial assessing the efficacy of the novel PneumoCool device to alleviate subjective shortness of breath.
- Trial name
- BREATHE-easy (NCT05416437)
- Testing
- PneumoCool, Current supportive measures that are used in the hospital for standard of care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Ohio State University
Dyspnea, Heart Failure
The Triple A Initiative Study ("Aktionsbündnis Akute Atemnot")
Acute dyspnea is a common chief complaint of patients presenting to the emergency department. Patients with acute dyspnea display a high mortality rate.
- Trial name
- NCT02049853
- Testing
- NTproBNP measurement with point of care device "Cobash232" in the POCT group
- Where
- 6 sites in Germany
- Volunteers
- 67 people
- Sponsor
- Prof. Dr. Michael Christ
Dyspnea, Quality of Life
Gastric Sleeve-Induced Weight Loss on Shortness of Breath in Obesity
Most research to date on bariatric surgery outcomes has been about metabolic syndrome, a disorder very effectively treated by bariatric surgery.
- Trial name
- NCT05812183
- Testing
- Bariatric surgery, Medical weight loss
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Shortness of Breath, Shortness of Breath/Dyspnea
Training Strategies to Maintain Performance
Statement of the Problem and Justification Cognitive performance under physiologically stressful conditions is critical in high-demand environments such as military operations, diving, and firefighting.
- Conditions
- Shortness of Breath, Shortness of Breath/Dyspnea, Respiratory Distress
- Trial name
- NCT07128511
- Testing
- Multiple Inhalation Breathing Pattern, Tactical Breathing Technique
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Florida
COPD
Assessment of Severity and Prognosis in Elderly Patients With COPD and Complex Chronic Comorbidities
Cigarette smoking, the major risk factor for Chronic Obstructive Pulmonary Disease (COPD), causes systemic effects, such as systemic cellular and humoral inflammation, that could substantially contribute to the development of…
- Trial name
- NCT01893918
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Copd
The Effect of Salt Water Nebulization on Cough, Sputum and Quality of Life in Chronic Obstructive Pulmonary Patients
The aim of this clinical trial is to evaluate the effects of salt-water nebulization on individuals with chronic obstructive pulmonary disease.
- Trial name
- NCT06519188
- Testing
- Nebulization application with 5 ml isotonic sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Ministry of Health, Turkey
Shortness of Breath
Impact of Facemasks on Running During COVID-19 Pandemic
Randomized crossover clinical trial in which a group of runners are ask to complete a 15 minutes standardized physical test on a treadmill.
- Trial name
- NCT04958863
- Testing
- Surgical mask, Polyester reusable mask
- Where
- Colombia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinica Valle del Lili
Dyspnea; Cardiac
Contribution LUS in the Diagnosis of Acute Heart Failure (AHF) in Patients Admitted to the ED
This study assesses the potential of lung ultrasonography to diagnose heart failure.
- Trial name
- NCT03717779
- Testing
- lung ultrasound
- Where
- Tunisia
- Volunteers
- 600 people
- Sponsor
- University of Monastir
Dyspnea, Pain
Effectiveness of I COUGH Program to Dyspnea, Respiratory Parameters, Mobility and Pain After Major Abdominal Surgery
The purpose of the current study was to investigate the effect of the I COUGH care program following major abdominal surgery dyspnea, oxygen saturation, pulmonary function, mobility, and pain after major abdominal surgery (MAS)…
- Conditions
- Dyspnea, Pain, Respiratory Insufficiency, Mobility Limitation
- Trial name
- NCT06255327
- Testing
- I COUGH care program
- Where
- 3 sites in Libya
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Chronic Obstructive Pulmonary Disease
Prevalence of Undiagnosed Chronic Obstructive Pulmonary Disease Sufferers in the Region of Murcia
The purpose of this study is determine the prevalence of undiagnosed Chronic Obstructive Pulmonary Disease (COPD) in population served and with exposure to cigarettes in the Region of Murcia
- Trial name
- NCT01380470
- Where
- Spain
- Volunteers
- 1,052 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Respiratory Disease, Respiratory Insufficiency
Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room
Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room In Late Preterm And Term Infants Wıth Respiratory Distress
- Trial name
- NCT04282369
- Testing
- HHHFNC, NCPAP, NIPPV
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
COVID-19, Heart Rate
Effect of Mask Use on Hemodynamic Responses During Exertion
The use of masks is a necessity due to the current pandemic conditions. The aim of the study is to examine the effects of the use of masks during effort on dyspnea and fatigue with hemodynamic parameters.
- Conditions
- COVID-19, Heart Rate, Blood Pressure, Exercise Test
- Trial name
- NCT05401331
- Testing
- Treadmilll, mask
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Breathlessness, COPD
Sentinel - Triaging Acute Breathlessness Using Multi-Modal Biomarkers
The Sentinel-001 study aims to identify a combination of biomarkers suitable for triage of breathlessness.
- Conditions
- Breathlessness, COPD, Asthma, Asthma Chronic
- Trial name
- NCT05304494
- Testing
- Biomarker tests for participant profiling
- Sponsor
- Sanome
Respiratory Decompensation, Multiple Disabilities
Long-term Use of Intrapulmonary Percussive Ventilation for Preventing Hospitalizations Due to Respiratory Decompensation in Children With Multiple Disabilities
Chronic respiratory failure is the leading cause of morbidity and mortality in children with multiple disabilities. Musculoskeletal disorders, swallowing disorders and ventilatory control abnormalities lead to progressive…
- Trial name
- PERKINE (NCT07473856)
- Testing
- Intrapulmonary Percussive Ventilation IPV
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pericarditis
Effects of Pulmonary Rehabilitation Versus Standard Care in Patients With Pericarditis
Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life.
- Trial name
- NCT07716696
- Testing
- Pulmonary Rehabilitation, Standard Care
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Covid19
Respiratory Muscle Function, Dyspnea, Exercise Capacity and Quality of Life in Severe COVID19 Patients
Further knowledge regarding sequelae in severe COVID-19 patients who have required ICU admission for invasive mechanical ventilation is still needed.
- Trial name
- NCT04853940
- Testing
- Data collection and clinical testing of subjects
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Heart Failure, Congestive
FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for Hospitalization.
The purpose of this study is to assess the safety and tolerability of two doses of nesiritide (a recombinant form of the natural human peptide normally secreted by the heart in response to heart failure) when administered…
- Trial name
- NCT00270361
- Testing
- nesiritide, usual long term cardiac medications
- Volunteers
- 214 people
- Sponsor
- Scios, Inc.
Depression, Pain
Improving Care of Patients With Heart Failure
Heart failure (HF) affects more than 5 million Americans and is a major source of morbidity and mortality. Despite optimal management, over half of patients with HF suffer from pain, dyspnea, fatigue, and depression that diminish…
- Conditions
- Depression, Pain, Dyspnea, Quality of Life
- Trial name
- NCT01461681
- Testing
- Symptom Management Service for Heart failure
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco