Clinical trials: Dyspepsia
Constipation and Dyspepsia
The Effects of Tegaserod vs. Placebo on Whole Gut Transit Time in Patients With Chronic Constipation and Dyspepsia
To demonstrate the effects of tegaserod on gastrointestinal scintigraphic orocecal transit in female patients with CC and upper GI symptoms of dyspepsia
- Trial name
- NCT00277550
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novartis
Dyspepsia, Functional Dyspepsia
A Long-term, Open-label, Uncontrolled Trial of YM443 (Z-338) in Patients With Functional Dyspepsia
To examine the safety and efficacy of Z-338 (YM443) after long-term administration in patients with functional dyspepsia, and also to examine the pattern of long-term administration.
- Trial name
- NCT00764374
- Testing
- YM443
- Where
- 4 sites in Japan
- Volunteers
- 412 people
- Sponsor
- Astellas Pharma Inc
Knee Osteoarthritis
Amtolmetin Gaucil in Knee Osteoarthritis
This study is conducted to study the efficacy and safety of Niselat in patients with osteoarthritis.
- Trial name
- AGATA (NCT02865161)
- Testing
- NISELAT
- Volunteers
- 220 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Indigestion Acid, Indigestion
A Clinical Study to Assess the Effectiveness of ENO Lime in Participants With Ajeerna Vyadhi (Acidity, Acid Indigestion, Indigestion, and Associated Nausea)
The primary purpose of this study is to assess the efficacy of ENO Lime (fruit salt) in participants with Ajeerna vyadhi (acidity, acid indigestion, indigestion, and associated nausea) at 15-minutes after administration of dose.
- Conditions
- Indigestion Acid, Indigestion, Nausea
- Trial name
- NCT07140341
- Testing
- ENO Lime
- Where
- 3 sites in India
- Volunteers
- 40 people
- Sponsor
- HALEON
Dyspepsia
Study of Motilitone to Treat Functional Dyspepsia
This study is to evaluate efficacy of the investigational drug Motilitone at 90 mg in patients with Functional Dyspepsia as measured by change in maximum tolerated volume and aggregate symptom score on the nutrient drink test.
- Trial name
- NCT02365701
- Testing
- Motilitone 30mg
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Dong-A ST Co., Ltd.
Dyspepsia, Helicobacter Pylori Infection
ERADICATE Hp - Treating Helicobacter Pylori With RHB-105
The "test and treat" strategy for treating dyspeptic patients who are H. pylori positive is rapidly becoming the standard of care. This study will test the effectiveness of RHB-105, a new triple therapy to treat H.
- Trial name
- ERADICATE Hp (NCT01980095)
- Testing
- RHB-105
- Where
- 12 sites in United States
- Volunteers
- 119 people
- Sponsor
- RedHill Biopharma Limited
Gastroesophageal Reflux Disease, Heartburn
Rubber Band Ligation and Mucosectomy for Gastroesophageal Reflux Disease (GERD)
The purpose of this study is to determine the safety and effectiveness of two separate procedures to treat gastroesophageal reflux disease (GERD) also known as heartburn.
- Conditions
- Gastroesophageal Reflux Disease, Heartburn, Regurgitation, Dyspepsia
- Trial name
- GERD (NCT01199679)
- Testing
- Mucosectomy, Rubber Band Ligation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cook Group Incorporated
Digestive System Disorders
Protocol: Phytomedicine-AMARGOL®, Clinical Trial for Efficacy Proof on Therapeutics
This is a Phase 3: Efficacy Study for AMARGOL® a phytomedicine used for asymptomatic digestive complaints.
- Trial name
- AMARGOL (NCT01485328)
- Testing
- AMARGOL®
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laboratorio Saude Ltda.
Post-cholecystectomy Gastrointestinal Spasms
Effectiveness of Duspatalin® in Patients With Post-cholecystectomy Gastrointestinal Spasm
Prospective, multicenter, non-comparative, observational program designed to assess the effectiveness of a 2-6 weeks treatment with Duspatalin® 200mg bis in die = twice a day (BID) and changes in quality of life in patients with…
- Trial name
- ODYSSEY (NCT02260154)
- Testing
- Mebeverine
- Where
- 21 sites in Russia
- Volunteers
- 220 people
- Sponsor
- Abbott
Indigestion, Nausea
YM443 in Subjects With Functional Dyspepsia
The primary objective of this study will be to characterize the dose response profile of YM443 in subjects with functional dyspepsia (FD) to enable the selection of doses for the Phase 3 clinical trial.
- Trial name
- NCT00102310
- Testing
- YM443
- Where
- 59 sites in United States
- Volunteers
- 416 people
- Sponsor
- Astellas Pharma Inc
Digestive Health, Indigestion
Efficacy of a Digestive Enzyme Blend
The purpose of this study is to investigate the effect of a digestive enzyme supplement (three times per day for 30 days) on gastrointestinal distress (GID) and body composition (body mass and body fat percentage) in healthy men…
- Conditions
- Digestive Health, Indigestion, Protein Digestion, Carbohydrate Digestion
- Trial name
- MULO (NCT04917913)
- Testing
- Digestive enzyme blend
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes
GERD (Heartburn, Regurgitation, and Dyspepsia), Gastroesophageal Reflux (GERD)
A Pre-market, Two-stages Interventional Clinical Investigation to Evaluate the Safety and the Performance of Fibroin Syrup in Reducing the Gastroesophageal Reflux Disease (GERD) Symptomatology in Nonerosive Reflux Disease (NERD) Patients
This study involves a medical device in the form of syrup, not yet on the market and tested for the first time in humans, named "FIBROIN SYRUP".
- Trial name
- NCT07563790
- Testing
- Syrup made by hyaluronic acid
- Where
- Italy
- Volunteers
- 47 people
- Sponsor
- Rose Pharma SA
Gastroesophageal Reflux, Heartburn
HEARD (Long Term) Study - Histology of the Esophagus in Acid-Related Disease
Determine if different levels of acid-suppression with esomeprazole for 6 months on chosen histological markers of esophageal epithelial acid-related disease in patients with upper GI symptoms.
- Conditions
- Gastroesophageal Reflux, Heartburn, Dyspepsia
- Trial name
- NCT00243724
- Testing
- Esomeprazole
- Where
- 10 sites in Canada
- Volunteers
- 350 people
- Sponsor
- AstraZeneca
Dyspepsia
Preliminarily Evaluate the Efficacy of Domperidone in Adult Chinese Participants With Functional Dyspepsia
The main purpose of the study is to assess the efficacy of domperidone in treatment of functional dyspepsia (FD) in Chinese participants and identify sub-populations (subtype of the disease) who are sensitive to domperidone…
- Trial name
- NCT03617016
- Testing
- Domperidone
- Where
- 5 sites in China
- Volunteers
- 160 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Dyspepsia
The Role of Tegaserod Therapy in the Management of Dyspeptic Symptoms in Female Patients on Proton Pump Inhibitors for the Treatment of Heartburn.
Study to provide initial data to assess the safety and efficacy of tegaserod use in patients with dyspepsia that are being treated with proton pump inhibitors (PPI's) for heartburn.
- Trial name
- NCT00171470
- Testing
- Tegaserod
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Novartis
Functional Gastrointestinal Disorders, Abdominal Pain
Pepsin in Patients With Functional Dyspepsia
This non-interventional, observational study investigates the course of symptoms in patients with functional dyspepsia under treatment with a fixed combination of pepsin and amino acid hydrochloride over a period of approximately…
- Conditions
- Functional Gastrointestinal Disorders, Abdominal Pain, Dyspepsia, Nausea
- Trial name
- NCT03076411
- Testing
- Pepsin
- Where
- Germany
- Volunteers
- 97 people
- Sponsor
- Nordmark Arzneimittel GmbH & Co. KG
Postprandial Distress Syndrome
Acotiamide vs Itopride in Postprandial Distress Syndrome
The goal of this study is to "To compare the efficacy and safety of Acotiamide versus Itopride in patient with post prandial distress syndrome type of functional dyspepsia"
- Trial name
- NCT07174297
- Testing
- Acotiamide
- Volunteers
- 152 people
- Sponsor
- Getz Pharma
Functional Dyspepsia
A Study to Evaluate the Efficacy and Safety of DA-9701 in Patients With Functional Dyspepsia
This study will evaluate the efficacy and safety of DA-9701 in patients with functional dyspepsia
- Trial name
- NCT07686679
- Testing
- DA-9701, DA-9701-R
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Dong-A ST Co., Ltd.
Gastroesophageal Reflux Disease With Dyspepsia Symptoms
Lansoprazole Tablets Special Drug Use Surveillance Gastroesophageal Reflux Disease With Dyspepsia Symptoms
To evaluate the efficacy of 4-week lansoprazole (Takepron) therapy for subjective symptomatic improvement in gastroesophageal reflux disease patients with dyspepsia symptoms
- Trial name
- LEGEND (NCT01990339)
- Testing
- Lansoprazole
- Volunteers
- 14,965 people
- Sponsor
- Takeda
Biliary Dyspepsia
A Study to Evaluate the Efficacy and Safety of CnU Cap. 500 mg in Patients With Biliary Dyspepsia
The objective of this clinical trial is to evaluate the efficacy and safety of CnU capsule 500 mg administration in patients with biliary dyspepsia
- Trial name
- NCT07016269
- Testing
- CnU capsule 500 mg(250mg 2 capsule)
- Where
- 8 sites in South Korea
- Volunteers
- 358 people
- Sponsor
- Myungmoon Pharma. Co. Ltd.