Clinical trials: Driving Ability
Automobile Driving
Driving Ability Evaluation System to Improve the Conditional Driving License System: Safety and Feasibility Study.
The primary objective of this study is to verify the safety and validity of a VR driving simulator developed for evaluating the driving abilities in healthy adults.
- Trial name
- NCT06279520
- Testing
- VR Driving Simulator, Computerized Neurocognitive Function Test, Driver Test Station
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chronic Pain
Use of Driving Tests to Evaluate Patient Performance on Oral Opioids
Many patients seen at Pain Centers are advised not to drive if they are on long-term opioid medications. Although such advice is routinely given considering patients' safety, unnecessary restrictions to driving can cause…
- Trial name
- OpDrive (NCT00659035)
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Asokumar Buvanendran
Attention Deficit Hyperactivity Disorder
Driving in Adults With Attention-deficit/Hyperactivity Disorder (ADHD) Before and During Treatment With Atomoxetine
According available data individuals with ADHD are impaired in their driving ability which can be improved by stimulant medication.
- Trial name
- DrivPerfATX (NCT00938743)
- Testing
- Atomoxetine
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Insomnia
Study of an Evening Dose of Eszopiclone on Next Day Driving Ability & Psychomotor/Memory Function in Healthy Volunteers
Male and female healthy volunteers. Patients must also possess a full current driving license (for at least one year), and be a regular car driver.
- Trial name
- NCT00368160
- Testing
- Eszopiclone
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sumitomo Pharma America, Inc.
Healthy
The Effect of Codeine on Driving Abilities
20 chronic pain patients using codeine are compared with 20 chronic patients not using opioids and 20 healthy volunteers with respect to driving ability measured by neurophysiological tests and driving in a car simulator.
- Trial name
- NCT00477178
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Seasonal Allergic Rhinitis, Driving Ability
Rhinitis, Cognition and Driving Performance
This study investigates the effects of Allergic Rhinitis (AR) on driving ability and memory functions. Our group has previously shown that patients suffering from AR symptoms perform less well on tasks requiring sustained…
- Conditions
- Seasonal Allergic Rhinitis, Driving Ability, Cognition
- Trial name
- NCT01318681
- Testing
- cetirizine 10 mg, fluticasone furoate
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Mental Health, Geriatrics
Impact of Cholinesterase Inhibitors on Driving Ability in Healthy Older Adults
The goal of the study is to assess the role of cholinesterase inhibitors in affecting the driving ability of cognitively intact seniors using driving simulators.
- Trial name
- NCT00482001
- Testing
- donepezil
- Where
- 2 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes
A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women
Researchers are looking for a better way to treat vasomotor symptoms (VMS), also known as hot flashes. Hot flashes are intense and sudden feelings of heat along with sweating and reddening of the skin.
- Trial name
- NCT06219902
- Testing
- Elinzanetant (BAY3427080), Zopiclone
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bayer
Cognitive Impairment
Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and Cognition
Every participant will receive active study drug and one (1 )comparator, in two (2) stages, one after the other. Each drug will be taken one (1) time after a high fat meal.
- Trial name
- NCT06382662
- Testing
- metaxalone m640 mg, tizanidine 8mg
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Primus Pharmaceuticals
Chronic Neuropathic Pain
Effects of Gabapentin in the Treatment of Neuropathic Pain on Driving Performance and Cognition
The aim of this study was to explore the effects of pain on the one hand and the effects of treatment of pain with gabapentin (900, 1200, 1800 or 2400 mg) on the other hand on actual driving performance and several laboratory…
- Trial name
- NCT00189072
- Testing
- gabapentin
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- UMC Utrecht
Primary Insomnia
Effects of One Evening Dose of 3 mg Eszopiclone on Next Day Driving Ability
To assess next day driving ability and psychomotor/memory function following a single night time dose of eszopiclone in insomnia patients.
- Trial name
- NCT00368056
- Testing
- Eszopiclone
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Sumitomo Pharma America, Inc.
ADHD - Attention Deficit Disorder With Hyperactivity, Driving Simulator Performance
Exploring Parameters of Driving Simulation in Relation to Drug Holidays in ADHD Patients
Attention deficit hyperactivity disorder (ADHD) or syndrome (ADHS) is a symptomatically defined condition that - if untreated - is linked to a significantly increased risk of traffic accidents.
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Driving Simulator Performance, ADHD, Driving Behavior
- Trial name
- DS-ADHD1 (NCT06910605)
- Testing
- "drug holidays" (D)
- Where
- Switzerland
- Volunteers
- 26 people
- Sponsor
- Stefan Lakämper
Mild Cognitive Impairment
Driving Ability Among People With Mild Cognitive Impairment
The Purpose of this study is to assess the effect of MCI on driving ability by using on road driving test. The relationship between their driving outcome and their cognitive decline will be examined.
- Trial name
- MCI (NCT01608256)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
ADHD
Methylphenidate and Driving Ability in Adult Patients With Attention-Deficit Hyperactivity Disorder
The primary purpose of this study is to determine the effects of methylphenidate versus placebo on driving ability of adult ADHD patients.
- Trial name
- NCT00223561
- Testing
- methylphenidate
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Schizophrenia
How Can a Driving Virtual Reality Tool Improve Quality of Life and Social Autonomy in Patients With Schizophrenia
Schizophrenia is a mental health issue that affects mostly young adults. The main symptoms are hallucinations, delirium, and agitation, poor social relations, lack of motivation, thought disorganization.
- Trial name
- Schizovirt (NCT03973853)
- Testing
- Virtual reality driving stimulation program, TAU
- Where
- 2 sites in France
- Sponsor
- Hôpital le Vinatier
Cognitive Aging
Intervention Comparative Effectiveness for Adult Cognitive Training
The study will compare the effect of broad and directed (narrow) technology-based training on basic perceptual and cognitive abilities in older adults and on the performance of simulated tasks of daily living including driving…
- Trial name
- ICE-ACT (NCT03141281)
- Testing
- BrainHQ, Rise of Nations, IADL Training
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Florida State University
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil
Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans
Alcohol is abused commonly, but there is no remedy for alcohol intoxication. This project is looking at the substance iomazenil and its effect on alcohol intoxication and alcohol's effects on driving using a driving simulator.
- Conditions
- Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil
- Trial name
- NCT01590277
- Testing
- Active Ethanol, Active Iomazenil
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cerebrovascular Accident
Promote Awareness of the Driving Abilities of Post-stroke Patients.
Patients with cerebrovascular accident (CVA) may present with a deficit of awareness of the disorders which results in a lack of correct self-estimation of their own abilities and difficulties in terms of both cognition and…
- Trial name
- AUTOCAM-AVC (NCT06530134)
- Testing
- Driving situation and video feedback, Driving situation and usual recommendations (without video feedback)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Insomnia
Effects of Ramelteon on Driving Ability
The primary purpose of this study is to investigate the effects of bedtime administration of a single dose of ramelteon (8 mg), zopiclone (7.5 mg), and placebo on next-morning on-road driving performance.
- Trial name
- NCT00319215
- Testing
- Ramelteon 8 mg, Zopiclone 7.5 mg
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences