Clinical trials: Drinking Behavior
Fetal Alcohol Spectrum Disorders, Pregnancy
CARRII Native Intervention Optimization Trial
The purpose of this study is to identify the best combination of new intervention components to use with CARRII, the first automated online intervention for alcohol-exposed pregnancies (AEP).
- Conditions
- Fetal Alcohol Spectrum Disorders, Pregnancy, Alcohol-Related Disorders, Drinking, Alcohol
- Trial name
- NCT07547696
- Testing
- CARRII Native Cores
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Alcohol Exposed Pregnancy, Unplanned Pregnancy
Optimizing a Digital AEP Risk Intervention With Native Women and Communities
The purpose of Aim 1 of the study is to gather quantitative and qualitative information to inform the development of a digital app tailored for Native American women to help them avoid a pregnancy affected by alcohol.
- Conditions
- Alcohol Exposed Pregnancy, Unplanned Pregnancy, Alcohol Use, Unspecified, Contraception Use
- Trial name
- CARRIINative (NCT06324929)
- Testing
- CARRII Native Rapid Pilot Testing
- Where
- United States
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Alcohol Drinking, Binge Drinking
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers.
- Conditions
- Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence
- Trial name
- NCT05522075
- Testing
- Exercise Training, Alcohol Abstinence Intervention
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Alcohol Use, Alcohol Drinking
Multi-Component Breath Alcohol Intervention Phase 3
This is the third stage of a three-stage, NIH-funded study to develop and test a multi-modal intervention concerning blood/breath alcohol concentration for young adults who drink heavily.
- Conditions
- Alcohol Use, Alcohol Drinking, Drinking Behavior
- Trial name
- BAMTECH (NCT06994962)
- Testing
- Alcohol-related mobile health technologies, Motivational interview and psychoeducation on blood/breath alcohol concentration, Lower tech facilitation
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Alcohol Use, Alcohol Drinking
Multi-Component Breath Alcohol Intervention
This is the first stage of a three-stage, NIH-funded study to develop and test initially a multi-modal intervention concerning blood/breath alcohol concentration for young adults.
- Conditions
- Alcohol Use, Alcohol Drinking, Drinking Behavior
- Trial name
- BAMTECH (NCT06124898)
- Testing
- Alcohol-related mobile health technologies, Motivational interview and psychoeducation on blood/breath alcohol concentration, Lower tech facilitation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Binge Drinking
Afferent Neurocardiac Signals, Cue Reactivity, and Cognitive Control
Conscious attempts to regulate alcohol use are often undermined by automatic attention and arousal processes activated by alcohol cues, as well as by diminished ability to inhibit in-the-moment behaviors.
- Trial name
- NCT05369169
- Testing
- Resonance breathing, Low demand cognitive task
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Alcohol Drinking, Tobacco Use
Journey of Transformation Curriculum for Native American Youth
The investigators will conduct a waitlist control trial to test the efficacy of the Journey of Transformation-Native Youth Health Leadership Program (JOT) in terms of delaying or reducing tobacco and other substance use and…
- Conditions
- Alcohol Drinking, Tobacco Use, Substance Use, Sexual Behavior
- Trial name
- JOT (NCT05731713)
- Testing
- Journey of Transformation-Native Youth Health Leadership Program curriculum
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Washington
Risky Health Behavior, Substance Use Disorders
The STop UNhealthy Substance Use Now Trial
The STop UNhealthy (STUN) Substance Use Now Trial (STUN II) is a multisite trial aiming to evaluate the comparative effectiveness of the following strategies for improving the implementation of screening and interventions for…
- Conditions
- Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder
- Trial name
- STUN II (NCT06524232)
- Testing
- Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI)
- Where
- 3 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Drinking Behavior, Drinking Excessive
Barbershop Talk: Reducing Excessive Alcohol Consumption Among Men
Unhealthy drinking is considered one of the top 10 public health concerns in the United States. Not only has heavy drinking been linked to poorer overall health and the chances of getting cancer and cardiovascular diseases, but…
- Conditions
- Drinking Behavior, Drinking Excessive, Drinking
- Trial name
- NCT05609344
- Testing
- SBIRT
- Where
- United States
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Heavy Drinking, Alcohol Drinking
A Brief Intervention for Young Adult Substance Users With Interpersonal Trauma
This proposal seeks to improve a mobile-based brief intervention for young adults who engage in heavy alcohol use and have experienced interpersonal trauma.
- Conditions
- Heavy Drinking, Alcohol Drinking, Substance Use, Drinking Behavior
- Trial name
- NCT07118826
- Testing
- Standard Brief Intervention, Trauma-Informed and Peer-Supported Brief Intervention
- Where
- United States
- Sponsor
- Western Kentucky University
Hypertension, Diabetes
A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti
Investigators will establish a longitudinal cohort of ~3,000 adults >18 years in Port-au-Prince using multistage random sampling, and follow them longitudinally to evaluate the prevalence and incidence of cardiovascular disease…
- Conditions
- Hypertension, Diabetes, Obesity, Kidney Diseases
- Trial name
- NCT03892265
- Testing
- Observational Study
- Where
- Haiti
- Volunteers
- 3,005 people
- Sponsor
- Weill Medical College of Cornell University
Lifestyle (Sedentary Behavior and Physical Activity), Mental Health
Lifestyle and Its Association With Maintaining Health
This study is part of the LIFEHEALTH project and will be carried out in five Mediterranean European Union countries: Croatia, Greece, Italy, Slovenia, and Spain.
- Conditions
- Lifestyle (Sedentary Behavior and Physical Activity), Mental Health, Nutrition, Sleep
- Trial name
- LifeHealth-OBS (NCT07309484)
- Where
- Croatia
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Zadar
Tobacco Smoking, Alcohol-Related Disorders
Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease
Many Veterans who have chronic conditions like cardiovascular disease or diabetes smoke or drink too much alcohol, which can worsen the condition.
- Trial name
- MINDSET (NCT07039175)
- Testing
- MINDSET, Usual Care
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
Semaglutide Therapy for Alcohol Reduction - Tulsa
The purpose of this research study is to determine if semaglutide, when compared to placebo, is safe and may reduce alcohol drinking in individuals who endorse symptoms consistent with alcohol use disorder.
- Trial name
- STAR-T (NCT05891587)
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Oklahoma State University Center for Health Sciences
Adolescent Drinking, Adolescent Substance Use
Optimizing and Advancing SBIRT in Schools
The goal of this clinical trial is to establish whether brief interventions for alcohol use can be delivered in schools for both indicated prevention and selected prevention, determine if an expanded workforce is an effective…
- Conditions
- Adolescent Drinking, Adolescent Substance Use, Risk Behavior, Health
- Trial name
- OASIS (NCT06206161)
- Testing
- Indicated Prevention, Clinical Staff, Selective Prevention, Expanded Paraprofessional Workforce
- Where
- United States
- Volunteers
- 21,000 people
- Sponsor
- Massachusetts General Hospital
Alcohol Use Disorder
Brain Connectivity Between Networks Implied in Inhibition and Cue-reactivity in Alcohol Use Disorder
Research about patients with alcohol use disorder has shown that task-related brain activation patterns as well as resting-state connectivity (measured with functional magnetic resonance imaging) change with clinical parameters…
- Trial name
- NIQA (NCT05843435)
- Testing
- Go-Nogo-task during functional magnetic resonance imaging, Resting-state functional magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Bern
Drinking Behavior
BC179 Relieves Discomfort After Drinking
To assess the effectiveness and safety of probiotic strain BC179 in reducing alcohol absorption in the gut, thereby lowering health risks.
- Trial name
- NCT06899620
- Testing
- Probiotic group
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Alcohol Use Disorder, Alcohol Abuse
Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder
Alcohol Use Disorders are currently positioned as the third leading cause of preventable death in the United States, constituting a humanitarian crisis with substantial financial burden on society and medical facilities.
- Conditions
- Alcohol Use Disorder, Alcohol Abuse, Alcoholism, Drinking Behavior
- Trial name
- NCT06415721
- Testing
- Active Transcranial Magnetic Simulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Palo Alto Health Care System
Alcohol Use, Unspecified, Substance Use
ANCHORS Alcohol & Sexual Health Study: UH3 Project
80 young adult men will complete an initial survey and receive 1 of 2 types of alcohol and sexual health education and information to encourage prevention of alcohol-related problems, HIV and other sexually transmitted infections…
- Conditions
- Alcohol Use, Unspecified, Substance Use, Sex Behavior
- Trial name
- NCT04331704
- Testing
- PrEP acronym (pre-exposure prophylaxis), Initial Web Survey, Interactive Voice Response (IVR) monitoring
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Florida