Clinical trials: Donor Nephrectomy
Laparoscopic Nephrectomy
Comparison of Ventilation Distribution Between Tidal Volume 6ml/kgBW and 10ml/kgBW
This study aims to compare the ventilation Distribution between tidal Volume 6ml/kgBW and tidal volume 10ml/kgBW in laparoscopic nephrectomy patients
- Trial name
- NCT02834039
- Testing
- Tidal volume 6 ml/kgBW, Tidal volume 10 ml/kgBW
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Postoperative Pain
Transversus Abdominis Plane Block Versus Wound Infiltration for Pulmonary Function Preservation Following Laparoscopic Living Donor Nephrectomy
This study compares two pain control techniques in patients undergoing laparoscopic kidney donation surgery: transversus abdominis plane (TAP) block versus wound infiltration with local anesthetic.
- Trial name
- TAPWIN (NCT06837909)
- Testing
- Transversus abdominis plane (TAP) block, Wound infiltration
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Renal Transplantation, Transplant Donation
Effect of a Preoperative Sensory Modulation Room on Pain, Anxiety, and Sleep in Kidney Transplant Patients
The goal of this prospective study is to evaluate whether preoperative exposure to a sensory modulation room can influence postoperative pain, anxiety, and sleep outcomes in adult living kidney donors and recipients.
- Conditions
- Renal Transplantation, Transplant Donation, Donor Nephrectomy
- Trial name
- SMRT-KT (NCT07533669)
- Testing
- Preoperative Sensory Modulation Session
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Living Donors, Nephrectomy
Use of Financial Incentives to Increase Live Kidney Donor Follow-up Compliance
This study evaluates whether using small financial incentives increases patient compliance with nationally-mandated living kidney donor follow-up at 6-months, 1-year, and 2-years after donation.
- Conditions
- Living Donors, Nephrectomy, Kidney
- Trial name
- NCT03090646
- Testing
- Financial Incentive
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Johns Hopkins University
Analgesia, Donor Nephrectomy
PQLB vs TFPB in HALDN
This prospective randomized non-inferiority trial is designed to compare postoperative analgesic effect of transversalis fascia plane block and posterior quadratus lumborum block in hand assisted laparoscopic donor nephrectomy.
- Conditions
- Analgesia, Donor Nephrectomy, Postoperative Pain, Fascial Plane Block
- Trial name
- NCT07852663
- Testing
- Quadratus Lumborum Block type 2, Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Koc University Hospital
Kidney Transplantation
Live Donors for Kidney Transplants
On a yearly basis there are approximately 12,000 kidney transplants in the United States. Presently there are approximately 40,000 patients awaiting a transplant with only 5,000 available donors.
- Trial name
- NCT00001856
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
End Stage Renal Disease
Assessment of Poles' Attitudes Towards Living Kidney Donation
The main goal of the project is to examine the public opinion on living kidney donation and to assess the knowledge of Poles in this field.
- Trial name
- NCT04789122
- Testing
- Attitude assessment
- Where
- Poland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
End Stage Renal Disease, Transplantation
Live Kidney Donor Study - Cross-Sectional and Historical Cohort Study
Kidney transplantation from living donors has been shown to carry many benefits over deceased donor transplantation. Because of benefits such as shorter waiting times and improved outcome for transplant recipients, living kidney…
- Trial name
- NCT00951977
- Where
- 3 sites in United States
- Volunteers
- 7,029 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Renal Transplant Donor of Left Kidney, Renal Transplant Donor of Right Kidney
Lowering Uric Acid in Live Kidney Donors
Recently there was described an increase in left ventricular mass after kidney donation. It is uncertain whether this is reversible or not.
- Trial name
- AL-DON (NCT03353298)
- Testing
- Allopurinol 300 mg
- Where
- Norway
- Volunteers
- 71 people
- Sponsor
- Oslo University Hospital
Healthy
The Effect of Lower Intraabdominal Pressure on Syndecan-1, sVEGF-R2, Occludin, KIM-1, and IL-6 on Living Donor Laparoscopic Nephrectomy
This study aimed to evaluate the increase of intraabdominal pressure 12- 14 mmHg caused by pneumoperitoneum resulted from carbon dioxide (CO2) insufflation induce glycocalyx endothelial injury that cause kidney tubular injury on…
- Trial name
- NCT03219398
- Testing
- Pneumoperitoneum pressure
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Chronic Kidney Disease
Culturally Sensitive Behavioral Interventions to Enhance Living Kidney Donation / Living Kidney Transplantation
Title: Culturally tailored behavioral interventions to enhance living kidney donation/living kidney transplantation Applicants: Johns Hopkins Medical Institutions, National Kidney Foundation of Maryland Principal Investigator…
- Trial name
- TALK (NCT00932334)
- Testing
- TALK PLUS, TALK Standard, Usual Care
- Volunteers
- 145 people
- Sponsor
- Johns Hopkins University
Kidney Donation/Transplantation
"Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail
To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients…
- Trial name
- NCT01248871
- Testing
- procedure:sevoflurane-remifentanil/sufentanil, volatile agent only during reperfusion, propofol-remifentanil/sufentanil
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- University Medical Center Groningen
Atelectasis, Postoperative, Pulmonary Complication
Evaluation of Perioperative Lung Ultrasound Scores (LUS) in Living Donor Nephrectomy Surgeries
Living donor nephrectomy surgeries can be performed in lateral position with laparoscopic technique which necessitates pneumoperitoneum. Considering the position and the pneumoperitoneum, lungs can be affected macroscopically.
- Trial name
- NCT05815888
- Testing
- Lung Ultrasound Score
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Living Donor Nephrectomy, Living Kidney Donation
Long-term Risk of Cardiovascular Disease in Living Kidney Donors
The investigative team will conduct a population-based, matched retrospective cohort study across Ontario, Alberta, and British Columbia using linked administrative healthcare databases to evaluate the long-term risk of major…
- Conditions
- Living Donor Nephrectomy, Living Kidney Donation, Living Kidney Donor, Living Kidney Donors
- Trial name
- NCT07431515
- Testing
- Nephrectomy
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Renal Transplant Donor of Left Kidney
Enhanced Recovery Open Versus Laparoscopic Donor Nephrectomy
A phase III randomized trial conducted to compare recovery outcomes between laparoscopic and open donor nephrectomy within a specified enhanced recovery protocol
- Trial name
- MEnROL (NCT02699489)
- Testing
- Laparoscopic donor nephrectomy, Open donor nephrectomy
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Kidney Transplant Donor
Modifiable Factors Affecting Racial Disparities in Kidney Donation
While many people offer to be evaluated at transplant centers as potential living donors to donate one kidney to someone they know, few ultimately donate. Racial/ethnic minorities are less likely to become living donors.
- Trial name
- NCT07793877
- Testing
- Not applicable- observational study
- Volunteers
- 2,332 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Renal Failure, Kidney Donors
BOne Dysfunction in Donor NEphrectomieS
Most dialysis patients die from vascular disease, which is statistically associated with changes related to chronic kidney disease associated mineral bone disorder (CKD-MBD)3-9.
- Trial name
- BONES (NCT04674397)
- Testing
- Radioisotope GFR test
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Manchester University NHS Foundation Trust
Organ Donor
Healthcare Access and Utilization Among Living Kidney Donors
This is a mailed survey to persons who served as living kidney donors at Saint Barnabas Medical Center. The experimental component of this study (the clinical trial) is a randomized trial of two monetary incentives for the living…
- Trial name
- NCT01009125
- Testing
- $2 cash, $5 cash
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- St. Barnabas Medical Center
Kidney Transplantation, Graft Failure
Evaluation of the Safety of Use of Anti-IL6 Receptor Antibodies to Reduce Allo-sensitization Post Allograft Nephrectomy
Graft nephrectomy is associated with massive allo-sensitization following this event. The occurrence of anti-HLA antibodies is a major barrier to perform a second kidney transplantation.
- Trial name
- RAIPONS (NCT04779957)
- Testing
- Tocilizumab
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse
Kidney Donation, Robotic Surgery
Comparison of Robot-assisted Donornephrectomy vs Hand-assisted Laparoscopic Donornephrectomy
The aim of this retrospective study was to analyze donor and recipient outcomes after robotic-assisted donor nephrectomy and hand-assisted laparoscopic donornephrectomy.
- Trial name
- NCT05194280
- Testing
- Robotic surgery
- Where
- Netherlands
- Volunteers
- 186 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)