Clinical trials: Docosahexaenoic Acid
Healthy
PET Imaging of DHA Metabolism
This study will examine the use of positron emission tomography (PET) for measuring docosahexaenoic acid (DHA) absorption from the blood into the brain. DHA is a type of fatty acid found in fish and other seafood.
- Trial name
- NCT00074503
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Social Anxiety Disorder
An Open Label Trial of Omega 3(o3mega+Joy)in the Treatment of Social Phobia
The primary objective is to evaluate the efficacy of an enteric-coated, eicosapentaenoic acid-concentrated fish oil in the treatment of social phobia.
- Trial name
- OMEGA3SP (NCT00485615)
- Testing
- Omega 3 Joy enteric coated concentrated fish oil
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- START Clinic for Mood and Anxiety Disorders
Healthy Volunteers
Bioavailability of EPA + DHA Enriched Canned Tuna and Its Acute Effects
Evidence has suggested that omega-3 fatty acids, namely eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have an important role in promoting cardiovascular health.
- Trial name
- NCT03742492
- Testing
- Meal containing canned tuna + fish oil (5 g EPA + DHA), Meal containing canned tuna + soybean oil
- Where
- Portugal
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Cancer Cachexia, Omega 3
Effects of Dietary Supplementation With omega3-fatty Acids (Fish Oil) and Progressive Resistance Training on Skeletal Muscle Status in Gynaecological, Gastrointestinal and Urological Cancer Patients
Cancer cachexia is a common and prognostically relevant complication of advanced malignancies, characterized by systemic inflammation, increased catabolism, and reduced nutritional intake, leading to a progressive loss of…
- Conditions
- Cancer Cachexia, Omega 3, Resistance Training, Cancer
- Trial name
- SUPPORT (NCT07643558)
- Testing
- Omega 3 FA (Fish Oil), Training
- Where
- Germany
- Volunteers
- 288 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
COVID-19 Disease
Study of LAU-7b for the Treatment of Coronavirus Disease 2019 (COVID-19) Disease in Adults
A randomized, double-blind, placebo-controlled Phase 2/3 Study of LAU-7b against confirmed COVID-19 Disease in hospitalized patients at a higher risk of complications.
- Trial name
- RESOLUTION (NCT04417257)
- Testing
- LAU-7b
- Where
- 29 sites in United States, Canada
- Volunteers
- 351 people
- Sponsor
- Laurent Pharmaceuticals Inc.
Nutrition, Healthy
A Dose Response Investigation of Docosahexaenoic Acid (DHA)
Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid (n-3 PUFA), commonly consumed from fish, that regulates many critical functions within the body including the brain, eye, and heart.
- Trial name
- DRI-DHA (NCT06294067)
- Testing
- docosahexaenoic acid (DHA)
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Chronic Obstructive Pulmonary Disease
Hydrolyzed Casein and Whey Protein Supplementation and the Addition of Leucine to Induce Protein Anabolism in Malnourished COPD Patients
The aim of this study is the first aim of a NIH project that consists of 3 aims. The first aim examines the acute effects of two high-quality milk proteins (casein vs.
- Trial name
- NCT01154400
- Testing
- Casein protein hydrolysates, Whey protein hydrolysates, Casein protein hydrolysates + LEU
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Texas A&M University
Type 2 Diabetes
Effects of Docosahexaenoic Acid (DHA) on Cardiovascular Disease on Diabetic Patients
Aim: to determine the effects of DHA supplementation: on the platelet function through their aggregation and the pathway of arachidonic acid metabolism on redox status on cells and plasma on inflammation in 16 type 2 diabetic…
- Trial name
- NCT01150292
- Testing
- First period DHA, Second period DHA
- Where
- 2 sites in France
- Volunteers
- 16 people
- Sponsor
- Hospices Civils de Lyon
Vegetarian Diet
Effects of the Consumption of a Supplement Rich in Docosahexaenoic Acid (DHA) From Algae
Vegetarian diets are increasing worldwide. To prevent nutritional deficiencies, supplementation with nutrients that are only present in animal food can be needed.
- Trial name
- NCT04278482
- Where
- Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Heart Disease
Eicosapentaenoic Acid (EPA)and Docosahexaenoic Acid Study
The goal of the study is to test the efficacy of an EPA-enriched oil made by DuPont versus a DHA-enriched oil, a standard fish oil preparation, and olive oil placebo in a double-blind, randomized, placebo-controlled trial.
- Trial name
- NCT01400490
- Testing
- EPA-DHA Study
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Research Associates
Prematurity, Subcutaneous Adipose Tissue
Fatty Acid Composition of Subcutaneous Adipose Tissue in Infants: A Prospective and Observational Study
The fatty acid composition in blood and subcutaneous adipose tissue of infants that have an clinical indicated operation is studied.
- Trial name
- NCT03785990
- Testing
- adipose tissue, blood, PEAPOD
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- University Hospital Tuebingen
Obesity, Inflammation
Effects of DHA on Pro-resolving Anti-inflammatory Mediators in Obese Patients Undergoing Weight-loss Treatment
Comparative, randomized, placebo-controlled, single-centre, single-blind clinical trial to assess the effectiveness of providing additional DHA omega-3 fatty acids supplements to increase the levels of pro-resolving and…
- Trial name
- NCT01865448
- Testing
- Omega-3 DHA
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Protein Supplies SL
Metabolic Syndrome, Overweight
Systematic Review and Meta-analysis of the Differential Effects of DHA and EPA on Inflammation
According to the World Health Organization, cardiovascular diseases (CVDs) are the number 1 cause of death globally. Systemic and local tissue inflammation is now recognized as a key etiological process leading to CVD.
- Conditions
- Metabolic Syndrome, Overweight, Obesity, Chronic Inflammation
- Trial name
- NCT03520556
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Laval University
Docosahexaenoic Acid Content of the Participants, Docosahexaenoic Acid Content of the Breast Milk
Effectiveness of Nutritional Resources for Milk Donors
Maternal diet influences breast milk nutritional profile; however, a national survey undertaken by the researchers revealed that non-for-profit donor milk banks in the U.K. do not provide specific dietary information to donors.
- Trial name
- VITAMIN (NCT07042009)
- Testing
- Nutritional resources, Milk docosahexaenoic acid levels
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Necrotizing Enterocolitis
Enteral Administration of Docosahexaenoic Acid to Prevent Necrotizing Enterocolitis in Preterm Neonates
The purpose of this study is to determine whether docosahexaenoic acid is effective in the prevention or reducing severity of necrotizing enterocolitis (NEC) in preterm neonates < 1500 g at birth who are starting enteral feeding.
- Trial name
- NCT01745510
- Testing
- Docosahexaenoic acid (DHA)
- Where
- Mexico
- Volunteers
- 225 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Breast Cancer, Obesity
A Pilot Study of Docosahexaenoic Acid (DHA) in Obese Menopausal Women
This study aims to determine if a supplement of an omega-3-fatty acid (docosahexaenoic - DHA) lowers inflammation in human fat tissue thereby lowering estrogen production and the potential risk for breast cancer.
- Trial name
- NCT01127867
- Testing
- dietary intervention
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Healthy
Effect of an Alpha-linolenic Acid-rich Supplement on Ketogenesis and Plasma Fatty Acids
Background: As the main alternative fuel to glucose for the brain, increased plasma ketones could potentially help compensate for brain glucose hypometabolism occurring during aging.
- Trial name
- NCT02410161
- Testing
- alpha-linolenic acid-rich supplement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Infant, Premature, Diseases
Enteral Supplementation With Docosahexaenoic Acid and Arachidonic Acid (DHA-AA) in Preterm Infants
Docosahexaenoic acid (DHA) and arachidonic acid (AA) have a critical effect on the health and neuronal development of the fetus and newborn.
- Trial name
- NCT06366893
- Testing
- DHA/AA emulsion supplement for preterm infant
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Cholesterol, Triglycerides
AlmegaPL CV Health Open Label Study
The aim of this study is to assess the effectiveness of Almega PL, a Nannochloropsis algae-derived extract rich in eicosapentaenoic acid (EPA), on improving blood markers associated with heart health of iwi customers.
- Conditions
- Cholesterol, Triglycerides, Omega-3, Eicosapentaenoic Acid
- Trial name
- NCT05267301
- Testing
- AlmegaPL (FDA NDIN # 826)
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Qualitas Health
Cancer Cachexia
A Pilot Study of Eicosapentaenoic Acid (EPA) in Patients With Cancer Cachexia
The data collected through this pilot study will allow us to increase our understanding of cancer cachexia and the effect of Eicosapentaenoic Acid (EPA) on cancer cachexia.
- Trial name
- NCT00815685
- Testing
- Eicosapentaenoic Acid
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute