Clinical trials: Distress
Acute Respiratory Distress Syndrome
A Realworld Study of Acute Respiratory Distress Syndrome in China
ARDS is a critical respiratory disease caused by endogenous and exogenous factors. The mortality of ARDS varies from 30 to 70%. In 2012, a new international diagnostic criterion has been put forward.
- Trial name
- CHARDSnet (NCT02975908)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China-Japan Friendship Hospital
Obesity
Trauma Exposure, Emotion Regulation and Eating Pathology in Obese Patients
The purpose of this study is to investigate the associations between lifetime exposure to traumatic events, emotion regulation strategies, and eating pathology of patients with obesity.
- Trial name
- TrOma (NCT03009825)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University of Paris 5 - Rene Descartes
Colorectal Cancer
An mHealth Symptom Management Intervention for Colorectal Cancer Patients (mCOPE)
The investigators have developed an innovative mobile health (mHealth) coping skills training protocol, mCOPE, that is adapted to meet the multiple symptom needs and stage-of-life challenges faced by young and middle-aged adults…
- Trial name
- NCT04763174
- Testing
- mHealth Coping Skills Training for Symptom Management (mCOPE)
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Duke University
Pneumonia, Viral
Assessment of the Risk of Pulmonary Embolism and Coagulation Profile in Patients With COVID-19 Lung Disease
The current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is complicated by pneumonia (15 to 20% of cases) requiring hospitalization with oxygen therapy.
- Trial name
- COVIDEP (NCT04479540)
- Testing
- Angiography scanner
- Where
- France
- Volunteers
- 117 people
- Sponsor
- Hopital Foch
Prematurity, Respiratory Distress Neonatal
Effect of Automated Oxygen Control on Early-childhood Lung Mechanics
Preterm infants are at higher risk of long-term respiratory problems and abnormal lung function in childhood. Respiratory support including mechanical ventilation, that is the use of a machine to move air into and out of the…
- Conditions
- Prematurity, Respiratory Distress Neonatal, Oxygen Delivery
- Trial name
- NCT07866820
- Testing
- Forced oscillometry technique
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College Hospital NHS Trust
Acute Respiratory Distress Syndrome, Mechanical Ventilation, Respiratory Mechanics, Ventilator-induced Lung Injury
A Modified Mathematical Model to Calculate Power Received by Mechanically Ventilated Patients With Different Etiologies
Ventilator-induced lung injury is a common complication. The latest and most noticeable theory of its pathogenesis is called 'ergotrauma' by Gattinoni in 2016.
- Trial name
- NCT04046380
- Testing
- work of breath measurement and calculation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Changhua Christian Hospital
Moral Injury, Moral Distress
A Study of Moral Distress, Moral Injury and Post-Traumatic Stress for Nurses
The goal of this descriptive study is to examine levels of moral distress (MD), moral injury (MI), \& post-traumatic stress (PTS) levels among nursing staff at Mayo Clinic. The main questions this study aims to answer are: 1.
- Conditions
- Moral Injury, Moral Distress, Post-Traumatic Stress, Nurse Well-being
- Trial name
- MDMIPTS (NCT07455370)
- Testing
- Surveys
- Where
- 3 sites in United States
- Volunteers
- 21,300 people
- Sponsor
- Mayo Clinic
Acute Respiratory Distress Syndrome
Stratification of the Acute Respiratory Distress Syndrome - A Second Phase Study
Current definitions of the Acute Respiratory Distress Syndrome (ARDS) could be adequate for epidemiological studies but are not adequate for inclusion of patients into therapeutic clinical trials.
- Trial name
- STANDARDS-2 (NCT02836444)
- Where
- 16 sites in Spain
- Volunteers
- 422 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Emotional Distress, Emotional Disorder
Mechanisms of Mindfulness Intervention: Distress Tolerance Dose Manipulation
This study hopes to: 1. explore whether an increase in the dosage of distress tolerance intervention corresponds to greater effectiveness of mindfulness intervention in alleviating emotional distress. 2.
- Trial name
- NCT06056232
- Testing
- Mindfulness Intervention for Emotional Distress(MIED)-normal version, Mindfulness Intervention for Emotional Distress(MIED)-increase distress tolerance, Mindfulness Intervention for Emotional Distress(MIED)-decrease distress tolerance
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University
Fetal Health Anxiety, Prenatal Distress
The Use of Virtual Reality Glasses in Women With Premature Rupture of Membranes
The Effect of Virtual Reality Glass Use on Fetal Health Anxiety, Prenatal Distress, and Maternal-Fetal Attachment in Women with Premature Rupture of Membranes: A Randomized Controlled Trial
- Conditions
- Fetal Health Anxiety, Prenatal Distress, Prenatal Attachment
- Trial name
- NCT07660393
- Testing
- Standard prenatal care, Nature-themed video
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Respiratory Distress Syndrome, Adult
Carbon Monoxide to Prevent Lung Inflammation
This study will examine in healthy volunteers how breathing carbon monoxide (CO) affects lung inflammation. Severe lung inflammation sometimes develops in patients with pneumonia or patients who develop serious blood stream…
- Trial name
- NCT00094406
- Testing
- Bronchoscopy, Bronchoalveolar lavage, Endotoxin
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
SARS-CoV Infection
VERU-111 in the Treatment of SARS-Cov-2 Infection by Assessing Its Effect on the Proportion of Patients Who Die on Study
To demonstrate the efficacy of VERU-111 in the treatment of SARS-Cov-2 Infection by assessing its effect on the proportion of patients who die on study (prior to Day 60).
- Trial name
- VERU-111 (NCT04842747)
- Testing
- VERU-111
- Where
- 58 sites in United States, Argentina and 4 more
- Volunteers
- 204 people
- Sponsor
- Veru Inc.
Burnout, Professional
Wellness and Distress in Health Care Professionals Dealing With End of Life and Bioethical Issues
Burnout, fatigue, distress and negative issues are in health care providers with different percentages. To date, little is known about the experience of burnout, fatigue and distress related with end of life and bioethical…
- Trial name
- WeStressHELL (NCT04434755)
- Testing
- health care professionals' exposure to bioethical issues
- Where
- 3 sites in Italy
- Volunteers
- 317 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Respiratory Distress Syndrome of Prematurity
Cerebral and Renal Oximetry Study in Preterm Patients Who Require Surfactant Administration
Respiratory distress syndrome of prematurity (RDSP) is an acute respiratory condition that occurs in preterm infants due to pulmonary surfactant deficiency.
- Trial name
- NCT05091840
- Testing
- oximetry monitoring
- Volunteers
- 40 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
First Pregnancy
The Effect of Prenatal Haptonomy on Anxiety, Distress and Psychological Well-being
Introduction:Anksiyete experienced during prenatal can increase Distress, cause negative perinatal outcomes, and adversely affect the psychological well-being.
- Trial name
- NCT05494840
- Testing
- Haptonomy
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Hilal Özbek
Acute Respiratory Distress Syndrome (ARDS), Microbiome Dysbiosis
Multi-Omics Integrative Analysis of Serum and Sputum to Uncover Key Determinants of Prognosis in Patients With ARDS
This study is a prospective observational investigation designed to systematically characterize key microbial signatures, metabolite profiles, and gene-expression features in serum and sputum from patients with acute respiratory…
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Microbiome Dysbiosis, Multiomics Analysis, Metabolomics
- Trial name
- NCT07380997
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Irritable Bowel Syndrome, Fibromyalgia
Psychological Risk Factors for Functional Somatic Disorders
The objective of this study is to explore the role of neuroticism, perceived stress, and adverse life events, respectively, in the development and perpetuation of functional somatic disorders.
- Conditions
- Irritable Bowel Syndrome, Fibromyalgia, Chronic Fatigue Syndrome, Somatoform Disorders
- Trial name
- NCT05631860
- Volunteers
- 7,493 people
- Sponsor
- University of Aarhus
Newborn Distress
A Pilot Study Using Laser Speckle Imaging of Neonate Cerebral Vasculature
The researcher want to know whether reflections of light can be used to provide real-time pictures of blood vessel formation around infants' heads. This approach is called laser speckle imaging
- Trial name
- NCT01166880
- Testing
- Laser Speckle Imaging
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Noninvasive Ventilation, Covid19
Predictors of Non-invasive Respiratory Support Failure in COVID-19 Pneumonia
The main objective of the current study is to search predictors of non-invasive respiratory support failure, like high -flow oxygen system (HFO) and pressure systems, Bilevel positive airway pressure (BiPAP) and continuous…
- Conditions
- Noninvasive Ventilation, Covid19, Distress; Respiratory Syndrome, Adult
- Trial name
- RUTIROX (NCT05094661)
- Testing
- BiPAP, CPAP
- Where
- Spain
- Volunteers
- 135 people
- Sponsor
- Germans Trias i Pujol Hospital
Acute Respiratory Distress Syndrome
Treatment of ARDS With Sivelestat Sodium
Neutrophil elastase (NE) released by neutrophils play an important role in inflammatory cascade and lung tissue injury of ARDS.Inhibition of NE is expected to prevent the pathophysiological process of ARDS and alleviate lung…
- Trial name
- TOAWSS (NCT04909697)
- Testing
- Sivelestat sodium, Saline
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Sichuan Provincial People's Hospital