Clinical trials: Dissociative Disorder
Non Epileptic Seizures, Functional Neurological Symptom Disorder
Ketogenic Diet Effects on the Frequency of Non Epileptic Seizures
The objective of this study is to determine the effects of the ketogenic diet on the frequency of non-epileptic seizures in patients with functional neurological symptoms disorder compared to a healthy diet.
- Conditions
- Non Epileptic Seizures, Functional Neurological Symptom Disorder, Conversion Disorder, Ketogenic Dieting
- Trial name
- NCT05219006
- Testing
- ketogenic dieting, healthy dieting
- Where
- Mexico
- Volunteers
- 17 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Dissociation, Depersonalization
Dissociation CBT Studies
Dissociation involves distressing feelings of unreality and disconnection. Evidence suggests it is particularly common amongst people with existing mental health difficulties, where it has been linked with greater clinical…
- Conditions
- Dissociation, Depersonalization, Dissociative Disorder
- Trial name
- DisCS (NCT06054009)
- Testing
- Brief CBT
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Birmingham
Globus Pharyngeus
Bump the Lump - Intervention for the Treatment of Globus Pharyngeus
To develop a standardized speech-language pathology treatment protocol to systematically address Globus pharyngeus (GP) as a proof of concept
- Trial name
- NCT06762444
- Testing
- Speech-language pathologist (SLP) protocol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Fibromyalgia
Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia
Previous studies of intravenous ketamine, which is a non-competitive N-methyl-D aspartate receptor antagonist, for fibromyalgia pain relief are limited to three studies.
- Trial name
- NCT06916403
- Testing
- Intravenous Ketamine Infusions
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Wilderman Medical Clinic
Posttraumatic Stress Disorders, Dissociative Identity Disorder
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.
- Trial name
- NCT02757339
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depressive Disorder
Phenomenological Explorations of the Esketamine-Induced Transient Dissociative State
Ketamine is an anaesthetic used in low doses to treat depressive disorders. A related molecule, Esketamine, has recently been launched on the market for the treatment of resistant depression.
- Trial name
- EXPEDIE (NCT06133309)
- Testing
- Experiential Phenomenological Interview
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Hepatocellular Carcinoma
Watch and Wait and Surgical Treatment for Clinical Complete Responders After Non-Curative Therapy for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) accounts for more than 90% of primary liver cancers and is the sixth most common cancer in the world and ranked third in mortality.
- Trial name
- WATCH (NCT05349331)
- Testing
- Liver Resection
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Sun Yat-sen University
Schizophrenia, Schizoaffective Disorder
24-Hour Time Course of Striatal Dopamine D2 Receptor Occupancy of Ziprasidone: A PET Study
Ziprasidone is recommended to be dosed twice daily for the treatment of schizophrenia, based on peripheral pharmacokinetics and a knowledge of its half life in plasma level (5-10 hours).
- Trial name
- NCT00818298
- Testing
- ziprazidone
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Centre for Addiction and Mental Health
Functional Movement Disorder
Study of the Ability of a New Technique to Effectively Diagnose Movement Disorders
Sante Fe is an investigation of a new technique to distinguish between different types of movement disorders, specifically organic versus functional, by observing changes in involuntary movements in two different situations.
- Trial name
- Sante-Fe (NCT03661021)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Acute Stress Reaction
Promoting Improved Functioning Among People Experiencing Stressful Situations
The iCOVER intervention was developed to rapidly restore functioning in individuals experiencing an Acute Stress Reaction (ASR). iCOVER is undergoing widespread adoption but has not been tested for efficacy.
- Trial name
- iCOVER (NCT06482567)
- Testing
- iCOVER, Physical Presence with Reassurance
- Where
- 5 sites in United States
- Volunteers
- 450 people
- Sponsor
- University of North Carolina, Chapel Hill
Functional Neurological Disorder
Feasibility of Remotely Measured Activity Behavior for Individuals With Functional Neurologic Disorder
This study evaluates whether remotely measured daily activity behavior, captured through a thigh-worn accelerometer, can serve as a reliable and ecologically valid indicator of symptom impact in individuals with Functional…
- Trial name
- NCT07478666
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Posttraumatic Stress Disorder, Depression
Efficacy of Narrative Exposure Therapy (NET) in Treating Women After Human Trafficking or Forced Prostitution
The purpose of this study is to perform an evaluation of a trauma-focused short-term intervention (Narrative Exposure Therapy; Schauer, M., Neuner, F.
- Conditions
- Posttraumatic Stress Disorder, Depression, Dissociation
- Trial name
- NCT00717548
- Testing
- Narrative Exposure Therapy
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University of Konstanz
Cancer
Neurophysiological Correlates of Dissociation Induced by Virtual Reality Hypnosis (VRH) in a Clinical Population
Hypnosis and virtual reality are potential tools for treating acute. Nevertheless, the neurophysiological correlates of such tools used together, i.e.
- Trial name
- NCT05362708
- Testing
- Clinical - Hypnosis with VR (VRH)
- Volunteers
- 40 people
- Sponsor
- University of Liege
Conversion Disorder, Parkinson Disease
Observational Study on "Functional Overlay" in Patients With Movement Disorders
The goal of this observational study is to learn about functional neurological disorders in patients with common non-functional movement disorders ("functional overlay").
- Conditions
- Conversion Disorder, Parkinson Disease, Tremor, Dystonia
- Trial name
- NCT05943652
- Testing
- Neurological examination, Anamnesis, Neuropsychological testing
- Where
- Austria
- Volunteers
- 216 people
- Sponsor
- Medical University of Graz
Functional Neurological Disorder
Pain Assessment and Transcranial Magnetic Stimulation Tolerability in Patients With a Functional Neurological Disorder
Functional neurological disorders (FND) are motor, sensory or cognitive symptoms without an identified lesion. This is a very common reason for consultation in neurology.
- Trial name
- NCT06149728
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Explorations Fonctionnelles Avicenne
Amblyopia
A Comparative Study Between Dissociative Treatment and Binocular Interactive Treatment in Amblyopia
Amblyopia is a unilateral or, infrequently, a bilateral reduction of best corrected visual acuity which cannot be attributed to coexisting eye or visual pathway disease.
- Trial name
- NCT03255707
- Testing
- eye patch, dichoptic treatment
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Functional Neurological Disorders
Functional Neurological Disorders in Patients Admitted in Stroke Units
Functional neurological disorders are an important subgroup of patients with stroke mimics admitted to stroke unit.Their clinical profile and outcome are poorly known.
- Trial name
- NEUROFON (NCT04662372)
- Testing
- Description
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pain, Acute
Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain
The objective of this study is to evaluate the potential opioid-sparing effect associated with the novel combination of fentanyl and sub-dissociative ketamine in adult patients with moderate to severe pain in the emergency…
- Trial name
- NCT03959852
- Testing
- Fentanyl, Fentanyl and Ketamine, Ketamine
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Dissociative Seizures, Functional Seizures
Assessing the Impact of Brief CBTi on Dissociative Seizures: SCED
Some people experience a temporary change in behaviour and consciousness, that often involves a collapse and/or shaking limb movements. These are referred to as 'Dissociative seizures'.
- Conditions
- Dissociative Seizures, Functional Seizures, Psychogenic Nonepileptic Seizures, Insomnia
- Trial name
- CBTi 4 DS:SCED (NCT06145971)
- Testing
- brief Cognitive Behavioural Therapy for Insomnia (bCBTi)
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- University of Glasgow
Functional Neurological Disorder
Psychoeducation Group Intervention for FND
This study aims to assess the feasibility of running a brief psychoeducation group intervention in an outpatient setting to assess the practicalities and benefits of offering this type of intervention for both clinicians and…
- Trial name
- NCT03857347
- Testing
- Psychoeducation Group for FND
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh