Clinical trials: Dissection, Aortic
Aortic Aneurysm, Aortic Dissection
Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study
The registry study aims to determine serial biomarkers to diagnosis and prognosis of aortic aneurysm/aortic dissection.
- Trial name
- NCT03233087
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Aortic Aneurysm, Aortic Dissection
Cerebral Protection in Aortic Arch Surgery
Aortic arch repair surgery is a technically complex and challenging procedure to treat aortic pathologies. Despite advancements in perioperative care, detrimental neurological complications occur during or after surgery.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Aortic Arch, Aortic Diseases
- Trial name
- NCT04966247
- Testing
- Microdialysis
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Barts & The London NHS Trust
Dissection, Aortic Diseases
Aortic Dissection fAlse enlarGement radIomics predictiOn
The objective of this study is to find, in acute phase of aortic dissection, CT scans characteristics through radiomics features, that can help us to predict a significant growth of dissected descending aorta or a false lumen…
- Conditions
- Dissection, Aortic Diseases, Aortic Dissection
- Trial name
- ADAGIO (NCT07117825)
- Testing
- AORTIC DISSECTION CT SCAN ANALYSIS
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Aorta Thoracic Ascending Dissection, Dissection of Descending Aorta
Clinical Profiles and Outcomes of Acute Aortic Dissection in the Chinese Patients
Clinical profiles and outcomes of patients with acute aortic dissection have not yet been evaluated in China. The aim of this study is to establish clinical registry of acute aortic dissection in China and to analyze clinical…
- Trial name
- CPOAADCP (NCT01606943)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xijing Hospital
Aortic Dissection, Biomarkers and Early Diagnosis
Potential Biomarkers for Early Diagnosis of Acute Aortic Dissection
Acute aortic dissection (AAD) is an acute vascular lesions with high early misdiagnosis rate(31.8%), and mortality rate was 38%. In recent years, the incidence is rising and serious threat to human health.
- Trial name
- NCT01860768
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Coronary Artery Disease, Arrhythmias, Cardiac
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear.
- Conditions
- Coronary Artery Disease, Arrhythmias, Cardiac, Heart Valve Diseases, Aortic Dissection
- Trial name
- PROSPECT (NCT06001073)
- Testing
- Observational; No Interventions were given.
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Aortic Dissection, Lung Infection
Population Pharmacokinetics of Lassila Tazobactam in Patients After Aortic Dissection
The individualized drug use research on optimizing piperacillin tazobactam for CRRT of hospital-acquired pulmonary infection after cardiopulmonary bypass is still in the initial stage at home and abroad, lacking systematic…
- Trial name
- NCT05349305
- Testing
- continuous renal replacement therapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
Thoracic Aorta
Aortic Elongation and Dissection
Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.
- Trial name
- NCT02722889
- Where
- Netherlands
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chest Pain Center, STEMI - ST Elevation Myocardial Infarction
Current Status and Determinants of Care for Patients With Acute Chest Pain in China: A Retrospective Analysis of Data From the China Chest Pain Center Registry
Chinese Cardiovascular Association is an association dedicated to establishing Chest Pain Centers in hospitals that have basic qualifications and meet pre-designed quality control targets.The vision of Chinese Cardiovascular…
- Conditions
- Chest Pain Center, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI), Unstable Angina (UA)
- Trial name
- NCT04014972
- Volunteers
- 3,000,000 people
- Sponsor
- China Cardiovascular Association
Distal Aortic Dissection, Dissection, Aortic Acute
ACute Uncomplicated Type b Aortic Dissection: Endovascular Repair vs. Best Medical Therapy
The purpose of the study is to conduct a randomized controlled trial comparing best medical therapy (BMT) alone to BMT with thoracic endovascular aortic repair (BMT+TEVAR) for uncomplicated acute type B aortic dissection.
- Conditions
- Distal Aortic Dissection, Dissection, Aortic Acute, Acute Type B Aortic Dissection (Uncomplicated)
- Trial name
- ACUTE-B (NCT02622542)
- Testing
- BMT+TEVAR, BMT
- Where
- 2 sites in United States
- Volunteers
- 436 people
- Sponsor
- The University of Texas Health Science Center, Houston
Aortic Aneurysm, Thoracic
Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Thoracic Aortic Aneurysms and Chronic Dissections
To ensure adequate seal of currently available stent grafts, a proximal 20 mm of healthy aorta is recommended. Extending the proximal landing zone into the arch by intentional covering of the left subclavian artery (LSA) without…
- Trial name
- MONA-LSA (NCT03738124)
- Testing
- Valiant Mona LSA Thoracic Stent Graft System
- Where
- 2 sites in France
- Sponsor
- University Hospital, Toulouse
Aortic Aneurysm and Dissection
Guo's Endovascular Aortic Arch Replacement of Aortic Dissection by WeFlow-Tribranch Endoprothesis: a Multicenter Pilot Study(GRAFT Study)
To explore the effect and prognosis of endovascular interventional therapy in high-risk patients with aortic arch dissection and aneurysm
- Trial name
- NCT05754541
- Testing
- WeFlow-Tribranch Aortic Arch Stent Graft System
- Where
- 4 sites in China
- Volunteers
- 20 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
CAD - Coronary Artery Disease, CABG
Soft Foam Dressings for Pressure Injury Prevention of Cardiac Surgery
The purpose of this study is to evaluate whether the application of soft foam dressings can reduce the occurrence of surgery-related pressure injuries among patients undergoing cardiac surgery.
- Conditions
- CAD - Coronary Artery Disease, CABG, Valve Disease, Heart, Aortic Diseases
- Trial name
- NCT07379294
- Testing
- CONVAFoam Hydrofiber Dressing, Standard Pressure Injury Prevention Care
- Volunteers
- 80 people
- Sponsor
- Shih,Wen-Chi
Aortic Dissection
Nordic Consortium for Acute Type A Aortic Dissection-2
The Nordic Consortium for Acute Type A Aortic Dissection-2 (NORCAAD-2) is a multicenter research collaboration involving up to 19 units in the Nordic countries and one in The Netherlands.
- Trial name
- NORCAAD-2 (NCT06862583)
- Testing
- surgery, endovascular intervention
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Karolinska Institutet
Aortic Dissection Type B, Intramural Hematoma
CRATOS - Evaluation of Cratos™ Branch Stent Graft System in Treatment of Descending Aorta Lesions
The goal of this prospective, interventional, multicentre, single-arm performance objective study is to evaluate efficacy and safety of Cratos™ Branch Stent Graft System in treatment of lesions (dissection, IMH and PAU in…
- Conditions
- Aortic Dissection Type B, Intramural Hematoma, Penetrating Aortic Ulcer
- Trial name
- NCT05874206
- Testing
- Cratos™ Stent Graft
- Where
- Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shanghai MicroPort Endovascular MedTech（Group）Co., Ltd
Aortic Aneurysm and Dissection
A Prospective Study of Discomfort Symptoms in Patients With Aortic Disease After Endovascular Intervention
The incidence and severity of post-procedural discomfort were evaluated in patients undergoing endovascular repair for aortic disease across six symptom-related dimensions: immobilization-related issues, puncture site discomfort…
- Trial name
- NCT07114185
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Type A Aortic Dissection
Safety and Efficacy of Aortic Root Reinforcement Combined With Vascular Grafts Eversion and built-in Procedure (XJ-procedure) in Patients With Acute Type A Aortic Dissection (ADVANCED-XJ )
This is a retrospective study based on the data available in our hospital database for ATAAD patients from January 2020 to December 2021.
- Trial name
- NCT05751200
- Testing
- No Intervention.
- Where
- China
- Volunteers
- 183 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Aortic Dissection
Prospective Study of Tailored Management Strategies for Malperfusion Syndrome
Management strategy of malperfusion syndrome in acute type A aortic dissection (ATAAD) patients remains controversial, with different views on when the surgery should be offered.
- Trial name
- NCT05517356
- Testing
- Tailored management strategies
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xiamen Cardiovascular Hospital, Xiamen University
Aortic Dissection, Aortic Aneurysm
Long-term Benefit of Aortic Stent-graft in Patients With Distal Aortic Dissection
Background: Aortic stent-graft is useful to occlude intimal tear and prevent further dilatation of the false lumen in patients with aortic dissection.
- Conditions
- Aortic Dissection, Aortic Aneurysm, Stent-graft
- Trial name
- NCT01354119
- Testing
- Aortic stent-graft
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Asan Medical Center
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
European Aortic Data Collection Project
The purpose of this study is to evaluate the safety and performance of Cook's various Custom-Made Stent-graft Devices (CMD) used for endovascular treatment of the aorta and related diseases by collecting information on the…
- Conditions
- Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Chronic Aortic Dissection
- Trial name
- EADC (NCT05896397)
- Testing
- Endovascular Aortic Treatments
- Where
- 18 sites in Denmark, France and 4 more
- Volunteers
- 600 people
- Sponsor
- Cook Research Incorporated