Clinical trials: Disorder of Upper Gastrointestinal Tract
Cholelithiasis, Epigastric Hernia
Using Pre-op Incentive Spirometer Reduces Chances of Basal Atelectasis in Patients Undergoing Upper Abdominal Surgeries
ABSTRACT Objective: To compare frequency of basal atelectasis in patients undergoing upper abdominal surgery who are provided pre-operative incentive spirometry versus those not provided pre-operative incentive spirometry
- Conditions
- Cholelithiasis, Epigastric Hernia, Duodenal Perforation
- Trial name
- NCT06115941
- Testing
- Pre-Op Incentive Spirometer
- Where
- Pakistan
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Dr. Muhammad Naeem
Lymphocytic Enteritis (Disorder), Healthy Volunteers
Evaluation of the Lymphocyte Subpopulations in the Normal Mucosa of the Upper Digestive Tract
The macro and microscopic findings of the upper gastrointestinal tract are useful in the differential diagnosis of digestive diseases such as Crohn's or celiac diseases.
- Trial name
- GUTproject (NCT05084807)
- Testing
- Endoscopy
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Mutua de Terrassa
Esophageal Neoplasms, Stomach Neoplasms
Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Improvements to treatment strategies for patients upper gastrointestinal cancers have produced an increasing population of people who remain free from disease recurrence in the long term.
- Conditions
- Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, Malnutrition
- Trial name
- NCT02385617
- Testing
- Octreotide
- Where
- 2 sites in Ireland, Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Multiple Primary Lung Cancer, Microbial Colonization
Exploratory Study of the Microbiome of Upper Gastrointestinal in the Pathogenesis of Multiple Primary Lung Cancer
This is an exploratory, single-center, being conducted at Beijing Haidian Hospital in order to detect the relationship between microbiome of upper gastrointestinal and pathogenesis of multiple primary lung cancer.
- Trial name
- NCT06973499
- Testing
- Microbiome Profiling and Symptom Assessment
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beijing Haidian Hospital
Upper Respiratory Tract Infection, Gut Microbiota
The Effect of Synbiotics on the Upper Respiratory Tract Infection
Gut microbiome manipulation to alter the gut-lung axis may potentially protect humans against respiratory infections. However, clinical trials of synbiotics, one of the microbiota-targeted intervention, in this regard is few.
- Conditions
- Upper Respiratory Tract Infection, Gut Microbiota, Immune Function
- Trial name
- NCT04960878
- Testing
- Synbiotic
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Esophagitis, Inflammation
Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule
The purpose of this research is to study the level of acid exposure above the gastroesophageal junction and the distal esophagus in patients with reflux symptoms using a capsule type acid measurement system.
- Conditions
- Esophagitis, Inflammation, Gastritis, Abdominal Pain
- Trial name
- NCT00579410
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cystic Fibrosis
Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Cystic Fibrosis
The primary aim of the study is to evaluate upper extremity exercise capacity, muscle oxygenation, balance and physical activity level in patients with cystic fibrosis..
- Trial name
- NCT04803643
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Type 2 Diabetes
Intraluminal Imaging of Duodenal Layer Morphometry in Patients With and Without Type 2 Diabetes
This observational study is conducted to determine how the duodenal layer thicknesses (mucosa, submucosa, and muscularis) vary with several factors in patients with and without type 2 diabetes.
- Trial name
- NCT02688920
- Testing
- EUS and OCT imaging
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Victoria Gomez
Upper Gastrointestinal Bleeding
Detection of Upper Gastrointestinal (GI) Bleeding Using a Novel Bleeding Sensor Capsule -Healthy Volunteers Study
The objective of the investigation is to evaluate the feasibility of detecting blood in healthy volunteers after ingestion of autologous blood mixed with water.
- Trial name
- NCT05631652
- Testing
- PillSense System
- Where
- Czechia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- EnteraSense Limited
Symptoms and Signs, Malignancy
Correlation of Endoscopic Findings and Symptoms in Patients Undergoing the First Upper Gastrointestinal Endoscopy
Endoscopy is the best means of finding early stage of upper gastrointestinal diseases, especially early cancer and benign ulcers.
- Conditions
- Symptoms and Signs, Malignancy, Ulcer Peptic
- Trial name
- NCT03736824
- Testing
- endoscopy
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Cancer Esophagus, Pancreatic Cancer
Effect of Chewing Gum on Postoperative Bowel Function Following Upper GI Tract Cancer Surgery
Every patient undergoing surgery in the abdomen will experience temporary paralysis of bowel function. This study evaluates whether chewing gum can reduce the bowel paralysis after surgery in patients undergoing either esophageal…
- Trial name
- NCT02260128
- Testing
- Chewing gum
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Michael Bau Mortensen
Gastric Lesion, Gastritis
Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities.
- Conditions
- Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia
- Trial name
- NCT06848400
- Testing
- AI-integrated Capsule Gastroscopy (ACG) examination, Electronic gastroduodenoscopy (EGD) examination
- Where
- 12 sites in China, Hong Kong and 1 more
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Upper Respiratory Tract Infections, Gastrointestinal Infection
Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children
this is a double-blind randomized placebo controlled clinical trial. 200 healthy children aged 12-48 months, attending day care or preschool for at least 5 days a week, regularly checked by the family pediatrician (FP) involved…
- Conditions
- Upper Respiratory Tract Infections, Gastrointestinal Infection, Children, Only
- Trial name
- FERCT19 (NCT05484102)
- Testing
- milk fermented with lactobacillus paracasei CBA L74
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bari
Disorder of Upper Digestive Tract
Near Infrared Optical Coherence Tomography of the Upper Aero-Digestive Tract
The Optical Coherence Tomography is a minimally-invasive diagnostic tool in both the office and operating room settings can identify sources of airway obstruction and effective surgical interventions.
- Trial name
- NCT00544427
- Testing
- Optical coherence tomography
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Gastric Cancer, Esophagus Cancer
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis
This study constitutes a case-control investigation employing a retrospective approach. Plasma samples from individuals with esophageal cancer, benign esophageal diseases, gastric cancer, benign gastric diseases, and a healthy…
- Trial name
- NCT06278064
- Testing
- Gastric Cancer, Esophagus Cancer
- Where
- 3 sites in China
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Upper Respiratory Tract Infections, Rhinopharyngitis
Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Upper Respiratory Tract Infections, Rhinopharyngitis, Sore Throat, Sinusitis
- Trial name
- NCT01315418
- Testing
- 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), 2-Non fermented dairy product (control)
- Where
- France
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Upper Gastrointestinal Bleeding (UGIB), Emergency Department Patient
A New Risk Score for the Emergency Department in Patients With Upper Gastrointestinal Bleeding
Abstract Background: The aim of this study was to develop a simpler, more practical, and highly effective risk scoring system for patients presenting to the emergency department with upper gastrointestinal bleeding.
- Conditions
- Upper Gastrointestinal Bleeding (UGIB), Emergency Department Patient, Risk Scores
- Trial name
- NCT06878183
- Testing
- Routine laboratory tests of the patients were examined (such as hemogram, biochemistry, bleeding parameters).
- Where
- Turkey (Türkiye)
- Volunteers
- 589 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Gastrointestinal Disease
Feasibility of Remote MCE for Upper GI Tract Examination Under Five-generation Network
With the combination of robotic and 5G network communication technology, telemedicine becomes more and more feasible and efficient.
- Trial name
- NCT04670692
- Testing
- 5G-MCE examination, MCE examination
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital