Clinical trials: Discomfort
Ocular Discomfort
Evaluation of the VisuXL® Performance on Ocular Surface Discomfort
VisuXL® is a medical device that is effective in various ocular surface disorders (ocular dryness, changes in the continuity of the corneal and conjunctival surface, environmental stress, exposure to UV and ionizing radiation…
- Trial name
- NCT03844737
- Testing
- VisuXL®
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- VISUfarma SpA
Hospitalism
Immersive Sensory Projections for Hospitalized Patients
The purpose of this study is to assess the impact of adding three sensory elements (visual, auditory, olfactory) on reducing discomfort in patients hospitalized in the intensive care unit/continuing care unit.
- Trial name
- IHP (NCT06577870)
- Testing
- Hospitalization in intensive care or continuing care unit
- Where
- France
- Volunteers
- 208 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Covid19
Self- Versus Conventional-swabbing for COVID-19 Screening (COVISWAB)
Self-swabbing requires less personal protective equipment and could allow to test more people and even to do quick self-diagnosis if antigenic tests are available.
- Trial name
- COVISWAB (NCT04831853)
- Testing
- nasopharyngeal swabbing procedure (self swabbing first), nasopharyngeal swabbing procedure (conventionnal swabbing first)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Nurse-Patient Relations
Research Project on the Risk of Discomfort, Pain, Alteration of Skin Condition in Bedpan Use by Patients and Caregivers
The hypothesis is that the current bedpan is not adapted to the diversity of patients encountered. It is necessary to collect the opinions of patients themselves on the current pool in different departments in order to validate…
- Trial name
- RIDAECUBA (NCT06332495)
- Testing
- Questioning the patient during hygiene care
- Where
- 5 sites in France
- Volunteers
- 300 people
- Sponsor
- Nantes University Hospital
Empathy, Discomfort
Effect of 'Empathy Dress' and Exercise on Midwifery Students' Discomfort, Empathy and Compassionate Love Levels
To investigate the effect of the exercise program with the 'Empathy Dress' applied to midwifery students on the Levels of physical discomfort, empathy and compassionate love in the midwifery department of Amasya University.
- Conditions
- Empathy, Discomfort, Love
- Trial name
- NCT05731921
- Testing
- The exercise program with the 'Empathy Dress'
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Amasya University
Pain
Novel Technique for Botulinum Toxin Injection to Minimize Patient Discomfort
This single blinded randomized pilot study was performed on 21 Caucasian females to determine if injections through follicular openings were less painful than traditional injections for cosmetic botulinum toxin type A injections.
- Trial name
- NCT00628472
- Testing
- botulinum type a
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Pleural Effusion
Impact of Pleural Manometry on Chest Discomfort After Therapeutic Thoracentesis
This randomized controlled trial attempts to determine whether the measurement of pleural pressures during therapeutic thoracentesis affects the development of chest discomfort after the procedure.
- Trial name
- NCT02677883
- Testing
- Manometry-guided thoracentesis, Symptom-guided thoracentesis
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Upper Gastric Discomfort
Effect of Consumption of Dairy Product on Upper Gastric Discomfort
The purpose of this study is to determine whether the consumption of test dairy products is effective in reducing upper gastric discomfort after 2 weeks of product consumption.
- Trial name
- NCT01422980
- Testing
- 1- Test dairy product containing specific ingredients, 2- Control dairy product without specific ingredients
- Where
- Argentina
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Patients Undergoing Diagnostic EGD
Meperidine for Patients Expected to Have Poor Tolerance During Diagnostic Esophagogastroduodenoscopy.
Our pilot results showed that meperidine reduce patient discomfort during EGD (esophagogastroduodenoscopy). But many patients can tolerate EGD well without any sedative agents.
- Trial name
- NCT01948921
- Testing
- Meperidine
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Dalin Tzu Chi General Hospital
Stress Urinary Incontinence
Sexual Fonction and Discomfort in Women After Midurethral Sling Surgery, Using PPSSQ
Evaluation of the sexual quality of life of women who had a sub-urethral sling several years ago, using a recently validated questionnaire: the PPSSQ (Pelvi-Perineal Surgery Sexuality Questionnaire).
- Trial name
- SEXBSU (NCT05527665)
- Testing
- Midurethral sling surgery
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Overactive Bladder
Procedural Discomfort Related to Number of Intradetrusor Botox Injections
Injection of intradetrusor OnabotulinumtoxinA (BTX-A) is a highly efficacious therapy with a reliable safety profile and demonstrable improvements in subjective and objective measures for overactive bladder (OAB) symptom control.
- Trial name
- BIND (NCT05652036)
- Testing
- Intradetrusor Botox Injections
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- The Methodist Hospital Research Institute
Urinary Catheter-Related Discomfort, Pressure Injury
Impact of Urinary Catheter Fixation on Meatal Pressure Injury in Male Patients in the Intensive Care Unit
Meatal pressure injury refers to the injury and ulceration of the head and shaft of the penis resulting from the constant pressure of an indwelling catheter.
- Trial name
- NCT06967116
- Testing
- Procedure Steps
- Where
- Turkey (Türkiye)
- Volunteers
- 248 people
- Sponsor
- Merve Zorlu
Needlestick Injuries
The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic
The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection.
- Trial name
- NCT02086292
- Testing
- 2 ml 1% Lidocaine, 1 ml 2% Lidocaine
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Urinary Bladder, Overactive, Pain
Myrbetriq™ (Mirabegron) to Reduce Pain and Discomfort Following Ureteral Stent Placement
The objective of this pilot study is to assess whether Myrbetriq™ will improve post-operative ureteral pain and discomfort, reduce bladder storage symptoms and increase quality of life following ureteral stenting.
- Conditions
- Urinary Bladder, Overactive, Pain, Lower Urinary Tract Symptoms
- Trial name
- NCT02462837
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Southern Illinois University
Musculoskeletal Diseases or Conditions
Ergonomic Benefits From Robotically Assisted Laparoscopy for Hysterectomies and Other Indications
This is a prospective, single-center, observational clinical trial at the Department of Women's Health of the University Hospital Tübingen.
- Trial name
- ERCON (NCT06109753)
- Testing
- Robotically Assisted Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- Germany
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Menstrual Discomfort
Probiotic and Gastrointestinal Symptoms Due to Menstruation in Healthy Women
In this double blind, parallel study, female participants who are on an oral contraceptive will consume either a probiotic or placebo supplement for approximately 8 weeks.
- Trial name
- NCT04457401
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Florida
Unidentified Gastrointestinal Discomfort Following Dairy Consumption
The Effect of Pasteurized; Pasteurized and Homogenized and UHT Treated Homogenized Cow's Milk on Gastrointestinal Symptoms in Sensitive Adults
This study aims to investigate differences in digestion rates and gastrointestinal problems caused by pasteurized; pasturized and homogenized as well as UHT-treated homogenized cow's milks in healthy adults by diary of symptoms…
- Trial name
- NCT03010904
- Testing
- Dietary intervention
- Where
- 2 sites in Finland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Turku
Joint Discomfort, Musculoskeletal Pain
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of resO™ Bone and Joint Support Postbiotic on Physical Function, Pain Interference, and Mobility in Adults With Joint Discomfort
This randomized, double-blind, placebo-controlled study evaluates the effects of resO™ Bone and Joint Support Postbiotic on physical function, pain interference, mobility, and recovery in adults aged 18-75 years experiencing…
- Conditions
- Joint Discomfort, Musculoskeletal Pain, Mobility Limitation
- Trial name
- RESO101 (NCT07602426)
- Testing
- Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Mammography, Breast Cancer
Self-compression Mammography in Clinical Practice
Every year millions of mammograms are performed worldwide, representing the primary examination for the early diagnosis of breast cancer.
- Trial name
- Pristina2/TR (NCT04009278)
- Testing
- Self compression arm
- Where
- Italy
- Volunteers
- 502 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS