Clinical trials: Disability
Substance Use Disorders
Efficacy of the Individual Placement and Support (IPS) Model
Hypothesis 1. Consumers with disabilities and co-occurring SUD receiving IPS will be more likely to be competitively employed (defined as 1 or more days of work over the past 30 days) at 3, 6 and 12 months following the…
- Trial name
- NCT01048346
- Testing
- Individual Placement and Support Model
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Wright State University
Fragile X Syndrome, FXS
A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome
This is a single-center, randomized, double-blind, 2-period crossover study to explore the effects of BPN14770 on cognitive function and behavior in subjects with Fragile X Syndrome.
- Conditions
- Fragile X Syndrome, FXS, Fra(X) Syndrome
- Trial name
- NCT03569631
- Testing
- BPN14770
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tetra Discovery Partners
Aging
Role of Exercise in Reversal of Hospitalization-associated Disability in Elderly
The proposed preliminary study from this interdisciplinary team will provide important information about the feasibility and safety of bedside low intensity pedaling exercise during hospitalization.
- Trial name
- NCT01901939
- Testing
- exercise
- Where
- United States
- Sponsor
- Palo Alto Veterans Institute for Research
Autism, Infant Development
Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement
The goal of this project is to measure the clinical utility of an objective and quantitative eye-tracking assay collected on a standalone, mobile investigational device to accurately screen 9-month-old infants for autism spectrum…
- Trial name
- NCT05916430
- Testing
- EarliPoint Investigational Device
- Where
- 2 sites in United States
- Volunteers
- 2,120 people, healthy volunteers welcome
- Sponsor
- Emory University
Lumbar Radiculopathy
Effects Of Spinal Mobilization With Leg Movement on Pain And Disability in Patients With Lumbar Radiculopathy
This study will be a Randomized Control Trial in which Both Genders with Age between 20 to 50 Years who had diagnosed with lumbar radiculopathy will be recriuted in to two groups.group A will be recieving spinal mobilzation with…
- Trial name
- NCT05955781
- Testing
- Spinal Mobilization With Leg Movement, Spinal Mobilization, Conventional treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Brain Diseases, Memory Disorders
Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation
The goal of this clinical trial is to investigate the impact of low intensity focused ultrasound pulsation (LIFUP) to two different brain regions, the amygdala and entorhinal cortex, in older adults.
- Conditions
- Brain Diseases, Memory Disorders, Learning Disabilities, Cognitive Impairment
- Trial name
- LIFUPMEMEMOT (NCT03717922)
- Testing
- Low Intensity Focused Ultrasound Pulsation to Amygdala, Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Spastic Cerebral Palsy, Dysarthria
Lateral Cord Magnetic Stimulation For Refractory Spastic Cerebral Palsy
Lateral cord stimulation (LCS) was discovered by the author as the producer of an average threshold increase for abnormal muscle contraction responses, in experimental pathological conditions, as described and referred.
- Trial name
- NCT03676439
- Testing
- Magnetic Spinal Stimulation
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- Sociedad Argenttina de Neuromodulación
Whiplash Injury of Cervical Spine
Ultrasound-guided Percutaneous Neuromodulation of the Accessory Nerve in Patients With Whiplash Injury
This study evaluates the improvement of patients with whiplash injury by comparing two statistical groups: a control group with exercise alone and an experimental group with exercise and percutaneous musculoskeletal…
- Trial name
- NCT07577037
- Testing
- Exercise, Ultrasounded Percutaneous Neuromodulation
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- CEU San Pablo University
Chronic Hip Pain, Worries; Pain or Disability
Effects of a Peri-operative Brief Mindfulness-based Intervention on Post-operative Pain and Disability
This study evaluates the effectiveness of a brief mindfulness-based intervention on post-operative pain and disability among anxious patients with chronic pain undergoing total hip arthroplasty.
- Conditions
- Chronic Hip Pain, Worries; Pain or Disability, Quality of Life
- Trial name
- CALM (NCT02861170)
- Testing
- Brief Mindfulness-Based Intervention
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Cervical Radiculopathy
Association Between Neck Disability Index Categories and Multidirectional Range of Motion in Patient With Cervical Radiculopathy
This study aims to investigate the association between NDI categories (None, Mild, Moderate, Severe) and ROM in six directions: flexion, extension, right and left side bending, and right and left rotation.
- Trial name
- NCT07152522
- Testing
- cross sectional observational
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fragile X Syndrome
Neurophysiological and Acute Pharmacological Studies in FXS Patients
The aim of this study is to utilize neurophysiologic assessments, behavioral measures and clinical measures to assess how much deficits associated with Fragile X Syndrome from pre-dose to post-dose using pharmacology.
- Trial name
- NCT02998151
- Testing
- Acamprosate, Lovastatin, Minocycline
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Fragile X Syndrome
Study of SPG601 in Adult Men With Fragile X Syndrome
This Phase 2 study described herein will evaluate the safety, efficacy, tolerability, pharmacokinetics and pharmacodynamics of SPG601 in adult men with Fragile X syndrome.
- Trial name
- NCT06413537
- Testing
- SPG601
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Spinogenix
Rotator Cuff Tendinopathy
Effects of TNT on Pain, ROM and Disability in Patients With RC Tendinopathy
EFFECTS OF TENDON NEUROPLASTIC TRAINING ON PAIN, RANGE OF MOTION AND DISABILITY IN PATIENTS WITH ROTATOR CUFF TENDINOPATHY
- Trial name
- NCT06707857
- Testing
- tendon neuroplastic training, conventional training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Low Back Pain
Effectiveness of Dry Needling in Patients With Chronic Nonspecific Low Back Pain
Low back pain is a major health problem that affects psychosocial, economical, functional and physical aspects of the patients' life.
- Trial name
- NCT05100381
- Testing
- dry needling
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Iran University of Medical Sciences
Low Back Pain
Low Back Pain in Mothers of Children With Disabilities
This is a cross-sectional study that aims to determine the prevalence of low back pain in mothers of children with disabilities following the COVID-19 pandemic and to describe its relationship with exposure to the virus, handgrip…
- Trial name
- NCT07106905
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Selvin BALKİ
Prader-Willi Syndrome
Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome
This Phase 3 study is designed to test the effectiveness of intranasal carbetocin (LV-101) in participants with Prader-Willi syndrome (PWS). Carbetocin is an oxytocin analog (a man-made chemical that is like oxytocin).
- Trial name
- CARE-PWS (NCT03649477)
- Testing
- 3.2 mg intranasal carbetocin, 9.6 mg intranasal carbetocin
- Where
- 24 sites in United States, Australia and 1 more
- Volunteers
- 130 people
- Sponsor
- Levo Therapeutics, Inc.
Neck Pain Chronic
Factors Associated With Pain Threshold in Young Adults With Chronic Neck Pain
The aim of this study was to determine which factors affect treatment expectations in individuals with chronic neck pain.
- Trial name
- NCT06946875
- Testing
- Pain Threshold
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- KTO Karatay University
Cervical Radiculopathy
Effects of Mulligan Belt Traction Versus Fisted Traction in Patients With Lower Cervical Spine Radiculopathy
Individuals with a lower cervical spine radiculopathy diagnosis will undergo screening to determine their eligibility based on inclusion and exclusion criteria. Eligible participants will be asked for their informed consent
- Trial name
- NCT07628439
- Testing
- muligan belt traction, Fisted traction
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Dementia, Cognitive Decline
Ammonia Levels and Cognitive Impairment
The purpose and objective of this study is to determine the prevalence of elevated ammonia levels in subjects with cognitive impairment, and to observe if treating the cause of the elevated ammonia level improves mental status.
- Conditions
- Dementia, Cognitive Decline, Cognitive Impairment, Developmental Delay
- Trial name
- NCT02059356
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Upper Crossed Syndrome
Effects of Post Isometric Relaxation and Janda's Approach in Patient With Shoudler Girdle Crossed Syndrome
Shoulder girdle crossed syndrome referred as upper crossed syndrome. In this syndrome, tightness of the upper trapezius and levator scapula on the dorsal side crosses with tightness of the pectoralis major and minor.
- Trial name
- NCT07064031
- Testing
- Neck Isometrics , TENS and Hot pack
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University