Clinical trials: Dilation
Gastric Dilation, Bowel Distention
Effect of Mask Ventilation on Surgical Field View in Robotic Colorectal Surgery
The goal of this clinical trial is to demonstrate the effects of pressure-controlled mask ventilation and non-mask ventilation during anaesthesia induction on gastric insufflation, gastric dilatation, increased bowel movements…
- Conditions
- Gastric Dilation, Bowel Distention, Surgical Procedure, Unspecified
- Trial name
- NCT07097129
- Testing
- Mask Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Koç University
Dyslipidemia
Study of Trilipix Effects on Lipids and Arteries
Fibrates reduce atherosclerosis and cardiovascular disease events. A major mechanism of this benefit appears to be their ability to raise plasma high density lipoprotein cholesterol (HDL-C), especially in patients with high…
- Trial name
- NCT01025492
- Testing
- Trilipix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obstruction of Esophagus, Respiratory Complication
Hemodynamic and Respiratory Effects of Esophageal Dilation in Children
The aim of this study compares hemodynamic and respiratory changes and complications in children who undergoing endoscopy for esophageal balloon dilatation and endoscopy for only control.
- Conditions
- Obstruction of Esophagus, Respiratory Complication, Hemodynamic Instability
- Trial name
- NCT02512770
- Testing
- endoscopic dilatation
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Asthma Control
OptimAIR: Towards Right Care in Asthma Through Point-of-care Phenotyping, Guideline-based Assessment and Management Optimalisation Using the AsthmaOptimiser in Primary Care
Asthma is mainly managed in primary care, yet disease control remains suboptimal. Many patients experience ongoing symptoms, exacerbations, and frequent short-acting β₂-agonist use, while underestimating the severity of their…
- Trial name
- OptimAIR (NCT07390669)
- Testing
- AsthmaOptimiser-supported structured asthma review
- Where
- 3 sites in Argentina, Chile and 1 more
- Volunteers
- 746 people
- Sponsor
- General Practitioners Research Institute
Eye Disease, Eye Care
Tailored Messages to Increase Eye Examination Behavior
The purpose of this project is to test two different types of health messages, one that is developed for a specific group (targeted) and the other that is more personalized to individuals (tailored), to see which is better at…
- Trial name
- NCT00649766
- Testing
- tailored newsletter, targeted newsletter
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Obesity
Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass
It is estimated that up to 20% of patients who have Roux-en-Y Gastric Bypass (RYGB) surgery will not meet their weight loss goal, or may even regain some of the weight they initially lost.
- Trial name
- NCT00394212
- Testing
- Transoral Suturing
- Where
- 10 sites in United States
- Volunteers
- 77 people
- Sponsor
- C. R. Bard
Wounds
Carbon Dioxide Infusion:Clinical and Histological Appraisal in Chronic Wounds
Carbon dioxide infusion is a non surgical procedure applied via percutaneous, transdermal and subcutaneous. Increase in the concentration of carbon dioxide decreases pH activating local nitric oxide that stimulates collateral…
- Trial name
- NCT01864967
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Institute of Assistance in Plastic Surgery, Sao Paulo
Coronary Artery Disease (CAD), Ischemic Heart Disease
Essential Pro PMCF Study ( rEPIC04E )
Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Essential Pro to meet EU Medical Device regulation (MDR) requirements in all the…
- Trial name
- rEPIC04E (NCT05292092)
- Testing
- Essential pro
- Where
- 7 sites in Spain
- Volunteers
- 161 people
- Sponsor
- Fundación EPIC
Acute Myocardial Infarction, Ischemic Cardiomyopathy
Long-term Evaluation of Patients Receiving Bone Marrow-derived Cell Administration for Heart Disease
This study will provide follow-up information and care of patients who have undergone autologous intracoronary bone marrow cell administration at our institution.
- Conditions
- Acute Myocardial Infarction, Ischemic Cardiomyopathy, Dilated Cardiomyopathy, Heart Failure
- Trial name
- BMC registry (NCT00962364)
- Testing
- autologous bone marrow-derived cells
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Procedural Sedation
A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures.
Very often patients receive medications before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation.
- Trial name
- NCT00327392
- Testing
- AQUAVAN® (fospropofol disodium) Injection
- Where
- 15 sites in United States
- Volunteers
- 123 people
- Sponsor
- Eisai Inc.
Corneal Ectasia
Evaluating Risk Factors of Post-LASIK Ectasia
Ectasia after refractive surgery is a relatively rare complication which can lead to sight-threatening complications if not detected and treated in time.
- Trial name
- NCT03708575
- Volunteers
- 25 people
- Sponsor
- Assiut University
Aortic Disease
Dosing of Amicar and Measure of Fibrinolysis by TEG During Cardiac Surgery
This study hopes to determine the optimal antifibrinolytic dosing to decrease bleeding and blood transfusion after cardiac surgery without increasing adverse events
- Trial name
- EACA (NCT01965730)
- Testing
- epsilon-aminocaproic acid (EACA)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
Cardiovascular Disease (CVD), Heart Failure
Study of the Progression of Chronic Cardiovascular Conditions
This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.
- Conditions
- Cardiovascular Disease (CVD), Heart Failure, Aortic Stenosis, Aortic Stenosis Disease
- Trial name
- OCORO (NCT07420907)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Prolaio
COPD Patients, Healthy
Determinants of the Vascular Response to Training in Chronic Obstructive Pulmonary Disease (COPD) Patients
Vascular comorbidities constitute a major burden in COPD patients. The atherosclerosis process is preceded by the onset of an endothelial dysfunction (assessed by the flow-mediated dilatation (FMD)), which is a risk factor for…
- Trial name
- cDysEndoBPCO (NCT03774238)
- Testing
- FMD analysis
- Where
- 2 sites in France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Preterm Birth
Labor Characteristics and Maternal-Infant Outcomes in Preterm Primiparous Women
This retrospective observational study evaluates labor characteristics in primiparous women with spontaneous preterm birth at different gestational ages and examines their associations with maternal and neonatal outcomes.
- Trial name
- NCT07844499
- Testing
- Gestational Age at Delivery
- Where
- China
- Volunteers
- 436 people
- Sponsor
- Maternal and Child Health Hospital, Jiading District
Legally Induced Abortion Without Mention of Complication
Mifepristone Versus Osmotic Dilators in Conjunction With Misoprostol for Cervical Preparation Prior to D&E at 14-19 Weeks
Dilation and evacuation (D\&E) is a common surgical procedure in the U.S. Adequate pre-operative preparation of the uterine cervix is an important part of preventing complications of the procedure.
- Trial name
- NCT02679092
- Testing
- Misoprostol, Mifepristone, Hygroscopic cervical dilators
- Where
- United States
- Sponsor
- Stanford University
Abortion Early
Dry vs Wet Misoprostol for Cervical Dilation in First Trimester Abortion
This study aims to verify whether the moisture of 400 µg of misoprostol pre uterine evacuation increases the dilatation of uterine cervix compared to dry misoprostol
- Trial name
- MisoWet (NCT02522078)
- Testing
- dry misoprostol, wet misoprostol
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cardiovascular Physiology
Effects of Tart Cherry and Aronia Extract Supplementation on Selected Physiological Parameters in Endurance-Trained Men
This study will evaluate the effects of four weeks of oral supplementation with a double-standardized tart cherry (Prunus cerasus) and aronia (Aronia melanocarpa) extract on cardiovascular regulation and exercise performance in…
- Trial name
- NCT07885098
- Testing
- Standardized Tart Cherry and Aronia Extract
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Cardiomyopathy, Dilated, 3B
CRT-P or CRT-D in Dilated Cardiomyopathy
The ICD-Reality study is a non-commercial, investigator-led, multicenter, prospective, randomized, controlled trial. We aim to determine the effect of CRT-D or CRT-P implantation in non-ischemic cardiomyopathy and heart failure…
- Trial name
- CRT-REALITY (NCT04139460)
- Testing
- CRT-D, CRT-P
- Where
- Czechia
- Volunteers
- 924 people
- Sponsor
- University Hospital Olomouc
Hereditary Hemorrhagic Telangiectasia, Idiopathic Vascular Ectasia
Pomalidomide in Hereditary Hemorrhagic Telangiectasia and Transfusion-Dependent Vascular Ectasia: a Phase I Study
This study will evaluate patients > 18 years of age with transfusion-dependent gastrointestinal bleeding due to documented gastrointestinal vascular ectasia with or without concurrent hereditary hemorrhagic telangiectasia (HHT).
- Trial name
- NCT02287558
- Testing
- Pomalidomide
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The Cleveland Clinic