Clinical trials: Dilation
Thrombosis, Menopause
Exercise Training and Thrombotic Risk in Post-menopausal Women
At menopausal transition, the risk of cardiovascular diseases increases. This is partly due to aging, but largely also the loss of estrogen, which has many positive effects on the circulation and protects against cardiovascular…
- Conditions
- Thrombosis, Menopause, Exercise Training, Vascular Dilation
- Trial name
- TIME (NCT04596501)
- Testing
- Early and late postmenopausal women
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Wounds
Carbon Dioxide Infusion:Clinical and Histological Appraisal in Chronic Wounds
Carbon dioxide infusion is a non surgical procedure applied via percutaneous, transdermal and subcutaneous. Increase in the concentration of carbon dioxide decreases pH activating local nitric oxide that stimulates collateral…
- Trial name
- NCT01864967
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Institute of Assistance in Plastic Surgery, Sao Paulo
Myocardial Infarction (MI), Hypertrophic Cardiomyopathy (HCM)
The Application of T1 Mapping in Real-World
The goal of this observational study is to create a comprehensive real-world spectrum of T1 mapping measurements across different heart conditions.
- Conditions
- Myocardial Infarction (MI), Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM), Arrhythmogenic Cardiomyopathy
- Trial name
- NCT07354646
- Testing
- Magnetic Resonance Imaging with Contrast
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Effect of Meperidine or Drotaverine on Effacement and Dilatation of the Cervix During Labor in Full Term Primigravidae
Meperidine Versus Drotaverine Regarding the Effect on the Duration of the First Stage of Labor in Full Term Primigravidae
Comparison Between Meperidine and Drotaverine Regarding the Effect on the Duration of the First Stage of Labor in Full Term Primigravidae
- Trial name
- NCT01236651
- Testing
- Meperidine, Drotaverine
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Renal Failure
Evaluation of Endothelial Dysfunction Using the "Flow Mediated Dilation" Test in a Population of Chronic Renal Failure Patients at Different Stages, and Evaluation of the Role of Antiphospholipid Antibodies
The vascular endothelium is an organ in its own right, playing, among other things, a primordial role in the control of vascular tone.
- Trial name
- NCT06347029
- Testing
- Urine sampling, Blood sampling, Flow mediated dilatation test
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Pain
Electrical Stimulation Over Acupuncture Points in Reduction of Rectal Discomfort Distension
Colonoscopy is a stressful and unpleasant procedure especially during the passage of the endoscope through angulations of colon. Electro-acupuncture is one of the alternative to reduce colorectal discomfort.
- Trial name
- NCT01551654
- Testing
- Transcutaneous Electrical Nerve Stimulation (ITO Company )
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Endothelial Dysfunction, Oxidative Stress
Creatine Monohydrate Supplementation and Vascular Endothelial Health
To determine the effects of 4 weeks of creatine monohydrate supplementation on markers of macrovascular and microvascular function, cognitive performance, and physical performance.
- Trial name
- NCT05014659
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Florida State University
Pain
Pupil Dilation and Analgesia Nociception Index
Pain assessment is crucial in clinical practice. Currently, subjective self-report is considered the most appropriate method to evaluate pain.
- Trial name
- NCT03280238
- Testing
- Measurement of pupil dilation and analgesia nociception index
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Sarcoidosis, Dilated Cardiomyopathy
Cardiac Sarcoidosis and FDG-PET
Sarcoidosis is a multi-systemic inflammatory disorder of unknown cause characterized by the formation of non-caseating granulomas in involved organs. Its cardiac involvement may be potentially fatal.
- Trial name
- NCT00958087
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kurume University
Hypertension
Neural Mechanism of Aldosterone-induced Insulin Resistance
Patients with high aldosterone hormone have higher blood glucose than normal people. This study is being done to understand how aldosterone hormone affects the nerve activity that controls blood flow in the muscles and blood…
- Trial name
- NCT02102243
- Testing
- DEFINITY® infusion, Human Recombinant Regular Insulin infusion, Dextrose infusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wanpen Vongpatanasin
HIV/AIDS
People Living With HIV/AIDS, Nitrate, Endotelial Function, Arterial Stiffness and Skeletal Muscle Oxygenation
Administration of antiretroviral therapy has brought benefits for infective human immunodeficiency virus-1 (HIV-1)-patients, reducing the number of AIDS-related morbidity and mortality.
- Trial name
- NCT03485248
- Testing
- Beetroot Juice
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Hysteroscopic Surgery, Pain, Postoperative
A Trial for Peroperative Procedure and Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine Administration
Dilatation of the cervix is necessary before operative hysteroscopic procedures. This dilatation with Hegar dilators has certain difficulties and is associated with pain.
- Trial name
- NCT03359655
- Testing
- Misoprostol, Hyoscine butyl bromide
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Abortion Late, Pain
Paracervical Block for Pain Control With Osmotic Dilator Placement
Cervical dilators are frequently used for preparation prior to second trimester surgical abortion. While their use decreases complications associated with surgical abortion, their placement is often uncomfortable for the patient.
- Trial name
- NCT02354092
- Testing
- Local anesthetic for tenaculum placement, Paracervical Block, Dilator Placement
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obstetrics, Labor
Clinical Evaluation of New Computerized Labor Monitoring System
The study is an open label feasibility study. The purpose of the study is to evaluate the ease of use of the Cervical ITR in terms of duration of attachment and number of detachments.
- Trial name
- CLM (NCT00496899)
- Where
- Israel
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Barnev Ltd
Laparoscopic Cholecystectomy, Abdominal Distention
Effects of Warm Water on GI System in Laparoscopic Cholecystectomy Patients
Objective: The study was carried out to determine the effect of drinking warm water on GIS functions in patients who underwent laparoscopic cholecystectomy surgery.
- Trial name
- LCSS (NCT06154928)
- Testing
- Drinking Warm Water Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- İslam Elagöz
Cardiovascular Physiology
Effects of Tart Cherry and Aronia Extract Supplementation on Selected Physiological Parameters in Endurance-Trained Men
This study will evaluate the effects of four weeks of oral supplementation with a double-standardized tart cherry (Prunus cerasus) and aronia (Aronia melanocarpa) extract on cardiovascular regulation and exercise performance in…
- Trial name
- NCT07885098
- Testing
- Standardized Tart Cherry and Aronia Extract
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Postural Tachycardia Syndrome (POTS)
Effect of Dietary Sodium Intake on Vascular Endothelium
The investigators will test the hypothesis that markers of vascular endothelial dysfunction will be exaggerated acutely with an extreme high sodium diet compared to an extreme low-sodium diet.
- Trial name
- NCT01550315
- Testing
- Pulsitile Arterial Tonometry (PAT) Protocol, Calf Blood Flow in Reactive Hyperemia (CBF-RH), Evaluation of Forearm-Mediated Dilation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
SLE, Cardiovascular Diseases
Flow Mediated Dilation in Association With Hyperuricemia
Assess cardiovascular affection and subclinical atherosclerosis in patients with systemic lupus using the non invasive flow mediated dilation.
- Conditions
- SLE, Cardiovascular Diseases, Atherosclerosis
- Trial name
- NCT05342285
- Testing
- Flow mediated dilation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
PCOS
Exogenous Ketone Supplementation in Females with Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) affects 1 in 5 females of reproductive age. Commonly characterized as a disorder of infertility, PCOS is often accompanied by 3 potent cardiovascular disease (CVD) risk factors: insulin…
- Trial name
- NCT06155708
- Testing
- Ketone, Water
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGill University
Pre Diabetes, Vascular Stiffness
Dietary Exchanges With Avocado and Mango in Pre-diabetes
The research is designed as a randomized, 2-arm, parallel, controlled, human clinical trial to investigate the effects of avocado and mango consumption for 8 weeks on indices of macro- and micro- vascular function in individuals…
- Conditions
- Pre Diabetes, Vascular Stiffness, Vascular Dilation, Cognitive Change
- Trial name
- AVMa (NCT05353790)
- Testing
- Meals + snacks: control, Meals + snacks: Avocado mango
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology