Clinical trials: Digital Ulcer
Diabetic Foot Ulcers (DFUs)
Evaluation of the Clinical Efficacy and Feasibility of Digital Foot Care Intervention Strategies With Different Intensities in the Prevention of Diabetic Foot Ulcers.
For people with diabetes who are at risk of foot ulcers, this study compares three digital foot care strategies (with different levels of intensity) to see which one is more effective at preventing ulcers and easier to use.
- Trial name
- NCT07185048
- Testing
- Conventional Foot Care Control Group, Digital Foot Care (Low-Intensity), Digital Foot Care (Moderate-Intensity)
- Volunteers
- 1,512 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Scleroderma, Scleroderma, Systemic
Telerehabilitation on Hand-Affected Scleroderma
Telerehabilitation Approach on Individuals with Hand-Affected Scleroderma
- Conditions
- Scleroderma, Scleroderma, Systemic, Scleroderma Associated Digital Ulcer, Hand Rheumatism
- Trial name
- NCT04684225
- Testing
- Hand Therapy via Telerehabilitation, Hand Therapy via home-exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University
Systemic Sclerosis Patients With Digital Ulcers
Effect and Safety of Local Injection of Botulinum Toxin Type B Against Digital Ulcer in Systemic Sclerosis
Efficacy and safety of local infusion of botulinum toxin type B in patients with systemic sclerosis (SSc) with digital ulcer is evaluated by a randomized, double-blind study.
- Trial name
- NCT03007004
- Testing
- Botulinum toxin type B (2500 units / vial), Physiological saline
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Gunma University
Active Digital Ulcers
Sildenafil for Treatment of Digital Ulcers in Patients With Systemic Sclerosis
This is a pilot study analyzing the effect of sildenafil therapy on digital ulcers in systemic sclerosis. We want to analyze ulcer healing by measuring the size of digital ulcers and their count and analyze the effect of…
- Trial name
- Sildenafil (NCT00624273)
- Testing
- Sildenafil therapy
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- Charite University, Berlin, Germany
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Crohn's Disease, Ulcerative Colitis
Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease
The bidirectional effects between psychological distress and inflammatory bowel disease (IBD) activity mean that not only does increased IBD activity trigger psychological distress, but psychological distress triggers increased…
- Conditions
- Crohn's Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
- Trial name
- DMBI (NCT06510296)
- Testing
- Digital Mind Body Intervention mobile application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Systemic Sclerosis, Raynaud Phenomenon
Rheopheresis for Raynaud's and Digital Ulcers in Systemic Sclerosis
In this feasibility study, we aim to explore therapeutic Rheopheresis (RheoP) as a novel treatment option for SSc-associated Raynaud's phenomenon and/or digital ulcers and compare it to the standard of care treatment (intravenous…
- Conditions
- Systemic Sclerosis, Raynaud Phenomenon, Digital Ulcer, Scleroderma
- Trial name
- RHEACT (NCT05204784)
- Testing
- Rheopheresis treatment, Intravenous Infusion
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Peter Korsten
Diabetic Foot Ulcer (DFU), Diabetes Mellitus
DiaFootCare to Promote Self-Care of Diabetic Foot Ulcers in Oman
This study aims to evaluate DiaFootCare, a mobile health application designed to support self-care and monitoring among adults with diabetic foot ulcers.
- Trial name
- DiaFootCare (NCT07815275)
- Testing
- DiaFootCare Mobile Application, Usual Diabetic Foot Care
- Where
- Oman
- Volunteers
- 139 people
- Sponsor
- Oman Ministry of Health
Digital Ulcers, Systemic Sclerosis
Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With Scleroderma
In an earlier clinical trial, RAPIDS-1, conducted in scleroderma patients with or without digital ulcers at baseline, bosentan significantly reduced the number of new digital ulcers versus placebo.
- Trial name
- RAPIDS-2 (NCT00077584)
- Testing
- Bosentan 62.5 mg, Bosentan 125 mg
- Volunteers
- 188 people
- Sponsor
- Actelion
Pressure Injury, Simulation Based Learning
Digital Twin-Haptic Integrated Mixed Reality Simulation
The responsibility for the management of pressure injuries belongs to nurses; the development of pressure injuries indicates that nursing care is not adequate.
- Conditions
- Pressure Injury, Simulation Based Learning, Nursing
- Trial name
- DT-HIMRS (NCT07310160)
- Testing
- Digital Twin-Haptic Integrated Simulation, High-Fidelity Simulation
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- NEBAHAT BORA GÜNEŞ
Scleroderma, Digital Ulcer
Effectiveness of Bosentan Therapy in Patients With Systemic scleRosis and Progressive Digital ulcEr Disease.
Digital Ulcers (DEs), are painful open sores on the fingers and toes and are due to limited perfusion of blood vessels in patients with Scleroderma.
- Conditions
- Scleroderma, Digital Ulcer, Autoimmune Diseases, Diffuse Cutaneous Systemic Sclerosis
- Trial name
- CURE (NCT05168215)
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Inflammatory Bowel Diseases, Anxiety
Digital Support for Mental Health Intervention in Patients With Inflammatory Bowel Disease
This is a small, exploratory study that will investigate using an artificial intelligence (AI) and virtual reality (VR), digital wellness application (app) to deliver a mental health support session in outpatient and hospitalized…
- Conditions
- Inflammatory Bowel Diseases, Anxiety, Depression, Ulcerative Colitis
- Trial name
- NCT06575660
- Testing
- Mental health support session
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Chicago
Ulcer, Scleroderma
Ozone Therapy in the Treatment of Digital Ulcers in Patients With Systemic Sclerosis
Digital ulcers (DUs) in scleroderma result from recurrent Raynaud's phenomenon (RP) and microtrauma with high impact on quality of life, management of DUs is a great challenge for clinicians.
- Trial name
- NCT02733978
- Testing
- the ozone generator device (Human Pro medic, German)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Digital Ulcers
Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients
The DUAL-2 study is designed as a multicenter, double-blind two-period study with an initial fixed 16-week Period 1, followed by a Period 2 of variable duration.
- Trial name
- DUAL-2 (NCT01474122)
- Testing
- Macitentan 3 mg, Macitentan 10 mg
- Volunteers
- 265 people
- Sponsor
- Actelion
Scleroderma, Systemic, Digital Ulcer
Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis
This study is performed to consider the safety and healing ability of diosmin in patients with systemic sclerosis (scleroderma) and open sores on their fingers (digital ulcers).
- Trial name
- NCT06256575
- Testing
- Diosmin
- Where
- 5 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Primus Pharmaceuticals
Raynaud Disease, Systemic Sclerosis
Treatment of Digital Ulcers in Korean Patients With Systemic Sclerosis: a Prospective Cohort Study
This study evaluates the efficacy and safety of routine medical treatments of digital ulcers in patients with systemic sclerosis in a prospective cohort study.
- Conditions
- Raynaud Disease, Systemic Sclerosis, Digital Ulcer
- Trial name
- NCT02642146
- Testing
- Calcium Channel Blockers, Phosphodiesterase Inhibitors, Endothelin receptor blocker
- Where
- South Korea
- Volunteers
- 71 people
- Sponsor
- Seoul National University Hospital
Raynaud's Phenomenon, Digital Ulcers
A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma
Raynaud's phenomenon (RP) associated with scleroderma is a difficult problem to treat. Many patients develop ischemic digital ulcers due to severe RP that causes considerable morbidity and adversely affects the quality of life.
- Conditions
- Raynaud's Phenomenon, Digital Ulcers, Scleroderma
- Trial name
- NCT01117298
- Testing
- Tadalafil
- Where
- 4 sites in India
- Volunteers
- 66 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Irritable Bowel Syndrome, Inflammatory Bowel Diseases
A Personalized Approach to Abdominal Pain in Irritable Bowel Syndrome
Apart from its use to provide insight in IBS disease courses and in clinical research, ESM can provide patients with feedback about individual triggers of their symptoms, and thereby function as part of a personalized therapeutic…
- Conditions
- Irritable Bowel Syndrome, Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- PERCEPTIvE (NCT05998577)
- Testing
- ESM and Traqq
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Maastricht University Medical Center
Type2diabetes, Rheumatoid Arthritis
Understanding Ayurveda Disease Conditions and Treatment Responses
The goal of this observational study is to assess Prakriti \& Vikriti in patients visiting OPD of IIISM department, SRM hospital.
- Conditions
- Type2diabetes, Rheumatoid Arthritis, Osteo Arthritis Knee, Skin Diseases
- Trial name
- NCT06167226
- Testing
- Personalized Ayurveda treatment protocol
- Where
- India
- Volunteers
- 497 people
- Sponsor
- Ayurai Private Limited
Pressure Injury
Telemedicine Wounds
This study aims to explore the effectiveness of the flipped education model applied to distance digital learning in enhancing the pressure injury staging interpretation skills of long-term care nursing staff.
- Trial name
- Staging (NCT06827925)
- Testing
- Distance Digital Learning
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Asia University