Clinical trials: Digestive Comfort
Digestion, Happiness
Parental Notions and Clinical Experiences About Child's Gut Comfort, Overall Satisfaction and Sense of Well-being When Consuming a New Toddler Milk
This is a prospective, open-label, single-arm study in a real-world setting of healthy Chinese toddlers provided with new toddler milk for a total of 4 weeks (28 days).
- Conditions
- Digestion, Happiness, Temperament
- Trial name
- NCT04768933
- Testing
- Toddler Milk
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Digestive Health, Quality of Life
Effect of a Fermented Dairy Protein With Prebiotic Fiber on GI Complaints
A positive impact of a fermented dairy protein with prebiotic fiber supplement on self-reported GI complaints and wellbeing has been suggested (Wardenaar et al. 2024).
- Trial name
- NCT06946017
- Testing
- Fermented dairy protein with prebiotic fiber supplement
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Palliative Care, Constipation
The Effect of Constipation Insoles on the Management of Constipation
Constipation is a common symptom among patients receiving palliative care and significantly affects their quality of life. Effective management of constipation requires both pharmacological and non-pharmacological approaches.
- Trial name
- NCT07339293
- Testing
- constipation insole, Walk
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Quality of Recovery, Urology
Postoperative Recovery and Comfort in Patients Undergoing Urologic Robotic Surgery
Previously published studies show that adding intrathecal morphine to general anesthesia can reduce the postoperative pain and length of stay (LOS) in varies types of surgery.
- Conditions
- Quality of Recovery, Urology, Pain, PONV
- Trial name
- NCT04694950
- Testing
- Usual care
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University
Endoscopic Submucosal Dissection
Endoscopic Submucosal Dissection (ESD)- Master Slave Robotic System - Human Study
The purpose of this study is to evaluate the feasibility, ease and safety of flexible endoscopic robotic system to treat early gastric cancer in humans.
- Trial name
- ESD (NCT01394861)
- Testing
- ESD using Master Slave Robotic System
- Where
- India
- Volunteers
- 3 people
- Sponsor
- Asian Institute of Gastroenterology, India
Liver Tumor
Is Thoracic Paravertebral Block a Better Option Than Conscious Sedation for PRFA of Liver Tumors
Percutaneus radiofrequency ablation (RFA) of liver tumors causes acute pain during the periooperative setting. In order to facilitate tumor access, patient should collaborate with a surgeon during the procedurę, therefore should…
- Trial name
- NCT04241887
- Testing
- thoracic paravertebral blockade, local anaesthesia
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- University of Warmia and Mazury
Short Bowel Syndrome (SBS)
Efficacy and Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome
The purpose of this study is to understand the safety and efficacy of twice weekly glepaglutide 10 mg in adult patients with short bowel syndrome (SBS), who were previously enrolled in the EASE SBS 2 or EASE SBS 3 trials.
- Trial name
- EASE SBS 6 (NCT07228403)
- Testing
- Glepaglutide 10 mg
- Where
- 16 sites in United States, Belgium and 5 more
- Volunteers
- 28 people
- Sponsor
- Zealand Pharma
Reflux, Gastroesophageal, Abdominal Pain
The Effect of Abdominal Massage Applied After Surgery
This research is carried out by research assistant Semiha Kurt under the supervision of Associate Professor Nuray TURAN. In this research aimed to examine the effect of abdominal massage applied after surgical ıntervention on…
- Conditions
- Reflux, Gastroesophageal, Abdominal Pain, Constipation, Diarrhea
- Trial name
- NCT05750186
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istanbul University
Healthy, Gastrointestinal Diseases
Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function
Human Milk Oligosaccharides (HMOs) are the third most abundant class of nutrients in human milk. Studies investigating the effects of dietary HMOs in infants have shown various health and developmental benefits such as the…
- Trial name
- NCT06094153
- Testing
- HMO 1, HMO 2
- Where
- Singapore
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kyowa Hakko Bio Co., Ltd.
Instrumental Delivery; Nec, Affecting Fetus or Newborn
Neonatal Outcomes in Instrumental Delivery
The aim of this study is to compare the impact of instrumental delivery on newborn head mark and newborn comfort over the impact of non-instrumental delivery.
- Trial name
- NCT03337880
- Testing
- instrumental delivery
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Poitiers University Hospital
Nausea, Emergency Department Patients
Effect of Antiemetic Timing on Nausea Severity and Patient Comfort in the Emergency Department
Nausea is a common symptom among patients presenting to the emergency department and can negatively affect patient comfort and clinical outcomes.
- Trial name
- ANTI-ED (NCT07523230)
- Testing
- Antiemetic Timing
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- muzeyyen ataseven
Inhalation; Oil
Effect of Peppermint Oil Inhalation on Postoperative Nausea, Vomiting and Comfort
Nausea and vomitting related to drugs and anesthetic methods are among the important postoperative problems. Nausea and vomitting causing illlness feeling of patient are frequent after surgical interventions, cause increased…
- Trial name
- NCT05585086
- Testing
- Peppermint Oil Inhalation
- Volunteers
- 60 people
- Sponsor
- Gümüşhane Universıty
Intubation Complication, Cold
The Effect of Cold Vapor on Intubation-Related Symptoms and Comfort in the Early Postoperative Period
Endotracheal Intubation (EI) is performed in order to monitor the effectiveness of anesthesia and to control the patient's breathing during the surgery under general anesthesia.
- Conditions
- Intubation Complication, Cold, Sore Throat, Cough
- Trial name
- NCT05317156
- Testing
- Cold vapor
- Volunteers
- 120 people
- Sponsor
- Istanbul Medeniyet University
Radio Dermatitis, Mucositis Oral
Using Red Light Therapy to Ease Skin Side Effects and Mouth Side Effects, in Children and Young People Aged 0 to 16 Years Old, Receiving Radiotherapy
The goal of this interventional study is to see if the daily use of red light therapy called photobiomodulation can help sore skin and sore mouths in children having radiotherapy.
- Conditions
- Radio Dermatitis, Mucositis Oral, Oesophagitis
- Trial name
- RADIANT (NCT07183267)
- Testing
- Photobiomodulation
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- The Christie NHS Foundation Trust
Training, Colonoscopy
The Impact of Remote Training on Colonoscopy KPIs
Colonoscopy is a complex, highly operator dependent, practical skill. The consistent attainment of key performance indicators (KPIs) by endoscopists depends primarily upon training.
- Conditions
- Training, Colonoscopy, Colorectal Cancer
- Trial name
- NCT06101836
- Testing
- Training intervention
- Where
- Belgium
- Volunteers
- 6 people
- Sponsor
- University Hospital, Ghent
Internal Hemorrhoids
Study About Patient Comfort and Long-term Outcome After Stapled Hemorrhoidopexy
The purpose of this study was to determine the influence on Patient comfort after Stapled Hemorrhoidopexy versus Milligan Morgan (two surgical procedures)in third degree circular hemorrhoids.
- Trial name
- NCT01533363
- Testing
- Stapled hemorrhoidopexy, Milligan Morgan
- Volunteers
- 130 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Short Bowel Syndrome
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension Trial
This trial is an extension trial to EASE SBS 2. The study looks at whether glepaglutide is a safe treatment for participants with Short Bowel Syndrome (SBS), as well as how well effectiveness is maintained during long term…
- Trial name
- EASE SBS 3 (NCT04881825)
- Testing
- Glepaglutide
- Where
- 19 sites in United States, Belgium and 6 more
- Volunteers
- 84 people
- Sponsor
- Zealand Pharma
Cholecystitis, Stress
The Effect of the Stress Ball Applied Before Colocystectomy Surgery on Patients; Surgical Fear, Anxiety and Comfort.
Cholecystectomy is the most common major abdominal surgical procedure in western countries. Patients may experience fear and anxiety before surgery.
- Conditions
- Cholecystitis, Stress, Fear, Comfort
- Trial name
- NCT06345768
- Testing
- Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Pelvic Organ Prolapse, Rectocele
Impact of Defecation Posture on Ease of Bowel Movements in Patients With a Rectocele
The study aims to determine if defecation posture, when using a defecation posture modification device (DPMD), will improve ease of bowel movements in patients with pelvic organ prolapse, specifically rectoceles.
- Conditions
- Pelvic Organ Prolapse, Rectocele, Bowel Dysfunction
- Trial name
- NCT06252714
- Testing
- Defecation Posture Modification Device
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- TriHealth Inc.
Spinal Surgery
Effects of Three Different Methods Applied to Patients After Spine Surgery on Nausea, Thirst and Comfort
The aim of this study was to determine the effects of postoperative methods on nausea, thirst and comfort levels of patients undergoing spinal surgery.
- Trial name
- NCT06857760
- Testing
- Ice cube, Mouth wash, Menthol lozenge
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ondokuz Mayıs University